Innovations in Biotechnology and Medical Sciences

Researchers one step closer to cracking Alzheimer’s puzzle

  1. Alzheimer’s disease is a progressive form of dementia that is characterised by loss of short-term memory, deterioration in behaviour and intellectual performance.
  2. It may occur in middle age or in old age.
  3. Scientists have caught a glimpse of the molecule during its attempt to enter a cell membrane, using a new method involving laser light and fat-coated silver nanoparticles.
  4. It is a rare protein and is difficult to probe.
  5. It was slightly fortuitous that we found it, using a modified version of Raman Spectroscopy.
  6. Usually the signal from this is weak, but we mimicked the cell’s outer layer by encasing silver nanoparticles in a fat membrane.

What is Raman Spectroscopy?

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