- Alzheimer’s disease is a progressive form of dementia that is characterised by loss of short-term memory, deterioration in behaviour and intellectual performance.
- It may occur in middle age or in old age.
- Scientists have caught a glimpse of the molecule during its attempt to enter a cell membrane, using a new method involving laser light and fat-coated silver nanoparticles.
- It is a rare protein and is difficult to probe.
- It was slightly fortuitous that we found it, using a modified version of Raman Spectroscopy.
- Usually the signal from this is weak, but we mimicked the cell’s outer layer by encasing silver nanoparticles in a fat membrane.
What is Raman Spectroscopy?