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GS Paper: GS3-17.Awareness in the fields of IT, Space, Computers, Robotics, Nano-technology, Bio-technology and issues relating to Intellectual Property Rights.

  • Genome sequencing of Coronavirus

    Scientists across the world are trying to develop a line of treatment and a possible vaccine for COVID-19. However, with the most optimistic timelines we don’t see a line of treatment or vaccine arriving before next year.

    Genome sequencing of Coronavirus

    • A global effort is on to collect and analyse the genetic composition of the new virus, which would be key to developing a cure and a vaccine.
    • Genome sequence is the unique code of genetic material of any organism, and determines the characteristic of any organism.
    • Whole genome sequencing is the process of determining the complete DNA sequence of an organism’s genome at a single time.
    • The gene composition of novel coronavirus, for instance, is different from that of the influenza virus. Every organism has a unique genome sequence.
    • Laboratories in various countries have been isolating and sharing the genome sequences of the virus on an international platform.

    Why are so many genome sequences being isolated?

    • When viruses multiply, or reproduce, there is a copying mechanism that transfers the gene information to the next generation.
    • However, no copying mechanism is perfect. When the virus multiplies, there will be small changes, which are called mutations.
    • These mutations accumulate over time, and after prolonged periods, are responsible for evolution into new organisms.
    • Within a single reproduction, the changes are extremely minor. More than 95 per cent of the gene structure remains the same.

    How it helps scientists?

    • However, the small changes that occur are crucial to understanding the nature and behaviour of the organism.
    • In this case, for example, the small changes could provide scientists with information about the origin, transmission, and impact of the virus on the patient.
    • It could also hold clues to the differing effects the virus could have on patients with different health parameters.

    How many genome sequences are required?

    • India has far fewer positive cases compared to China, South Korea, Iran, Italy, or even the US.
    • Patients who have been infected with the virus in similar conditions are unlikely to show any significant changes in the genome sequences.
    • Patients with existing medical conditions could be other candidates from where genome sequences of this virus could be isolated.
    • This could help scientists to look for clues to possible impact of virus amidst those existing medical conditions.

    Currently, what is the most effective medication?

    • As of now, there is none such. Right now, drugs are being repurposed, meaning old drugs for similar diseases are being checked for their efficacy against COVID-19.
    • These drugs, if they work, will require clinical trials, and then can be made widely available for people.
    • In most cases, symptomatic treatment for fever, body ache, and cough will be sufficient. More severe cases will require oxygen and respiratory support.
  • How plants dissipate excess sunlight as heat?

    Photosynthesis is a life-sustaining process by which plants store solar energy as sugar molecules. However if sunlight is in excess it can lead to leaves being dehydrated and damaged.

    What is Photosynthesis?

    • Photosynthesis is the process used by plants, algae and certain bacteria to harness energy from sunlight and turn it into chemical energy.
    • There are two types of photosynthetic processes: oxygenic photosynthesis and anoxygenic photosynthesis.
    • The general principles of anoxygenic and oxygenic photosynthesis are very similar, but oxygenic photosynthesis is the most common and is seen in plants, algae and cyanobacteria.
    • During oxygenic photosynthesis, light energy transfers electrons from water (H2O) to carbon dioxide (CO2), to produce carbohydrates.
    • Ultimately, oxygen is produced along with carbohydrates. Oxygenic photosynthesis is written as follows:

    6CO2 + 12H2O + Light Energy → C6H12O6 + 6O2 + 6H2O

    Here, six molecules of carbon dioxide (CO2) combine with 12 molecules of water (H2O) using light energy. The end result is the formation of a single carbohydrate molecule (C6H12O6, or glucose) along with six molecules each of breathable oxygen and water.

    How do plants dissipate heat?

    • To prevent such damage, plants dissipate extra light as heat.
    • While this was known there has been a debate over the past several decades over how plants actually do so.
    • Now for the first time researchers have directly observed one of the possible mechanisms through which plants dissipate extra sunlight.
    • The new research has been able to determine–by using a highly sensitive type of spectroscopy–that excess energy is transferred from the pigment chlorophyll, which gives leaves their green colour, to other pigments called carotenoids.
    • The carotenoids then release the energy as heat. After the carotenoids accept excess energy, most of it is released as heat, thus preventing damage to the cells.

    Why does plant dissipate light?

    • During photosynthesis, light-harvesting complexes play two seemingly contradictory roles.
    • They absorb energy to drive water-splitting and photosynthesis, but at the same time, when there’s too much energy, they have to also be able to get rid of it.
    • Plants quickly adapt to changes in sunlight intensity. Even in very sunny conditions, only 30 per cent available sunlight is converted into sugar, and the rest is released as heat.
    • The excess energy, if not released, leads to the creation of free radicals that can damage proteins and other important cellular molecules.

    Significance of the research

    • So far, it had been difficult to observe the heat dissipation phenomenon, given that it occurs on a very fast time scale, in femtoseconds or quadrillionths of a second.
    • Using the new technique, researchers could observe that chlorophylls absorb red light and carotenoids absorb blue and green light, thus being able to monitor energy transfer.
  • N95 Mask

    In a new mandate to curb unnecessary demand, the Maharashtra Food and Drug Administration said that chemists cannot sell N95 masks without a doctor’s prescription. The FDA also warned that serious action would be taken against those who are found selling masks at high prices or hoarding them.

    Why such a move?

    • Personal Protective Equipment (PPE) kits and N95 masks are being sold at very high prices in medical shops. The State has received many complaints about the same.
    • It has also been found that many are making bulk purchases and hording PPE kits and N95 masks.
    • Since the COVID-19 outbreak in China, shortage of PPE gear and masks has been reported from across the world.
    • While the Indian government has currently banned exports of N95 masks, the manufacturers are focussed on making other surgical marks to get good returns from exports.

    N95 mask

    • A disposable N95 mask (respirator) is a safety device that covers the nose and mouth and helps protect the wearer from breathing in some hazardous substances.
    • An N95 respirator is designed to achieve a very close facial fit and very efficient filtration of airborne particles.
    • The ‘N95’ designation means that when subjected to careful testing, the respirator blocks at least 95 percent of very small (0.3 micron) test particles.
    • If properly fitted, the filtration capabilities of N95 respirators exceed those of face masks. However, even a properly fitted N95 respirator does not completely eliminate the risk of illness or death.
  • [pib] Quantum coin or ‘qubit’ and Entanglement Theory

    Researchers from Raman Research Institute (RRI), an autonomous institution under the Dept. of Science & Technology, have devised a new test for fairness of quantum coin or ‘qubit’ using entanglement theory. The Qubit is the basic unit of information in a quantum computer.

    Entanglement Theory

    • It is a special type of correlation that exists in the quantum world with no classical counterpart.
    • The researchers from RRI made use of this quantum resource to arrive at a test for fairness of a quantum coin (a qubit).
    • Their strategy, which makes use of entanglement, enables better discrimination between quantum states. Such advantage is valuable in quantum sensors.
    • This work is a significant contribution to the domain of quantum state discrimination, which is an essential aspect of quantum information science.
    • It brings out the crucial role of entanglement in improving our ability to discriminate quantum states.
    • In this work the researchers concretely implemented the theoretical idea on the simulation facility of the IBM quantum computer.

    Quantum coins

    • By repeated trials, one can determine the fairness of a classical coin with a confidence which grows with the number of trials.
    • A quantum coin can be in a superposition of heads and tails.
    • Given a string of qubits representing a series of trials, one can measure them individually and determine the state with a certain confidence.
    • The team has shown that there is an improved strategy which measures the qubits after entangling them, which leads to a greater confidence.

    Significance

    • This is a significant contribution to quantum state discrimination, an essential aspect of quantum information science which is expected to influence quantum sensing.
    • The domain of Quantum Information and Quantum Computing Technology is a growing area of research which is expected to influence Data Processing, which in turn, plays a central role in our lives in this Information Age.
    • For instance, bank transactions, online shopping and so on crucially depend on the efficiency of information transfer.
    • Thus the recent work on quantum state discrimination is expected to be valuable in people’s lives in the current era.
  • [pib] Polymer Electrolyte Membrane Fuel Cells (PEMFC)

    Scientists at International Advanced Research for Powder Metallurgy & New Materials (ARCI), Hyderabad have developed Polymer Electrolyte Membrane fuel cells (PEMFC).

    Polymer Electrolyte Membrane Fuel Cells

    • Proton-exchange membrane fuel cells, also known as polymer electrolyte membrane (PEM) fuel cells (PEMFC) are a type of fuel cell being developed mainly for transport applications, as well as for stationary fuel-cell applications and portable fuel-cell applications.
    • Their distinguishing features include lower temperature/pressure ranges (50 to 100 °C) and a special proton-conducting polymer electrolyte membrane.
    • PEMFCs generate electricity and operate on the opposite principle to PEM electrolysis, which consumes electricity.
    • They are a leading candidate to replace the aging alkaline fuel-cell technology, which was used in the Space Shuttle.

    Working

     

    • The PEMFC uses a water-based, acidic polymer membrane as its electrolyte, with platinum-based electrodes.
    • The protons pass through the membrane to the cathode side of the cell while the electrons travel in an external circuit, generating the electrical output of the cell.

    Applications in disaster management

    • Emergency Operation Centres (EOC) backed with 10 kW systems is being planned as a natural disaster management measure.
    • Tamil Nadu is generally affected by five to six cyclones every year, of which two to three are severe and is followed by frequent power cuts.
    • ARCI is now planning to set up a PEMFC system for Tamil Nadu to operate the systems like early warning systems, VHF set, IP phone, BSNL Ethernet and office equipment like scanner, computers, printers, phone, FAX and normal requirements like lighting and fan.
  • NASA’s new Mars rover: Perseverance

    NASA has named its next Mars rover ‘Perseverence’.

    About Perseverance

    • The Perseverance rover weighs less than 2,300 pounds and is managed by NASA’s Jet Propulsion Lab.
    • The rover’s mission will be to search for signs of past microbial life. It will also collect samples of Martian rocks and dust, according to the release.
    • The rover will also be tasked with studying the red planet’s geology and climate.
    • All of NASA’s previous Mars rovers — including the Sojourner (1997), Spirit and Opportunity (2004) and Curiosity (exploring Mars since 2012) — were named in this way.
  • Media Access Control (MAC) Binding

    After seven months, the use of social media was allowed in Jammu and Kashmir with an order laying down the latest rules for the use of the Internet in the UT.  Among various conditions, the order says Internet connectivity will be made available “with mac-binding”.

    What is Mac-binding?

    • Every device has a Media Access Control (MAC) address, a hardware identification number that is unique to it. While accessing the Internet, every device is assigned an IP address.
    • Mac-binding essentially means binding together the MAC and IP addresses, so that all requests from that IP address are served only by the computer having that particular MAC address.
    • In effect, it means that if the IP address or the MAC address changes, the device can no longer access the Internet.
    • Also, monitoring authorities can trace the specific system from which a particular online activity was carried out.

    Permitted connections

    • The Internet can be accessed on all postpaid devices, and those using Local Area Networks (LAN).
    • While the postpaid SIM card holders shall continue to be provided access to the Internet, these services shall not be made available on prepaid SIM cards unless verified as per the norms applicable for postpaid connections.
    • Apart from this, special access terminals provided by the government will continue to run.
    • It is further directed that the access/communication facilities provided by the government, viz. e-terminals/Internet kiosks apart from special arrangements for tourists, students, traders etc shall continue.

    Only 2G permitted

    • Internet speed in J&K is still restricted to 2G.
    • This means very slow services — pictures will take a long time to be sent or downloaded, videos will be nearly impossible to share, and there will be a long loading time for most websites.
    • It also means that although in theory, the “whitelist system” — where people could only access some websites pre-approved by the government — has been removed, some sites designed for a 4G Internet experience will hardly work.

    Have curbs been lifted?

    • Not exactly. The latest order is to remain in force till March 17 unless modified earlier.
    • The government has been relaxing Internet and phone usage in the UTs in phases.
  • Unguarded X hypothesis

    Men outnumbered women by 37 million in the 2011 Census of India, but among those over the age of 60, there were more than 1 million more women than men. In general, men live shorter lives than women worldwide. This is due to the chromosomal differences between the two, points’ new study.

    What are Chromosomes?

    • The human body is made up of cells, and in the centre of each cell is the nucleus. Chromosomes, which are located inside the nucleus, are structures that hold the genes.
    • It is the genes that determine the various traits of an individual including eye colour, blood type — and sex.
    • The human cell has 23 pairs of chromosomes. One pair is of the sex chromosomes, named X and Y, which determine whether an individual is male or female.
    • A female has two X chromosomes (XX) while a male has one X and one Y (XY).

    Unguarded X hypothesis

    • This hypothesis suggests that the Y chromosome in XY is less able to to protect an individual from harmful genes expressed on the X chromosome.
    • In a male, as the Y chromosome is smaller than the X chromosome, it is unable to “hide” an X chromosome that carries harmful mutations, which may later expose the individual to health threats.
    • On the other hand, the hypothesis goes, there is no such problem in a pair of X chromosomes (XX) in a female.
    • If one of the X chromosomes has genes that have suffered mutations, then the other X chromosome, which is healthy, can stand in for the first, so that the harmful genes are not expressed.
    • This maximizes the length of life, according to the hypothesis. And this is what the UNSW researchers set out to examine.

    Testing the hypothesis

    • In a statement issued by UNSW, PhD student and study first author Zoe Xirocostas said the
    • Unguarded X hypothesis appears to stack up, after examining the lifespan data available on a wide range of animal species.
    • Researchers studied lifespan data in not just primates but mammals and birds, but also reptiles, fish, amphibians, arachnids, cockroaches, grasshoppers, beetles, butterflies and moths among others.
    • It was found that across that broad range of species, the heterogametic sex (XY in humans) does tend to die earlier than the homogametic sex (XX in humans).
  • [pib] Amendment to the Export Policy of APIs and formulations made from these APIs

    The Government has made amendments in the export policy and restricted export of specified APIs (Active Pharmaceutical Ingredients) and formulations made from these APIs.

    Active Pharmaceutical Ingredients (APIs)

    • All drugs are made up of two core components: the API, which is the central ingredient, and the excipients, the substances other than the drug that helps deliver the medication to your system.
    • The API is the part of any drug that produces its effects.
    • Excipients are chemically inactive substances, such as lactose or mineral oil.
    • The quality of APIs has a significant effect on the efficacy and safety of medications.

    The notification covers the following APIs and formulations made from these APIs:

    • Paracetamol
    • Tinidazole
    • Metronidazole
    • Acyclovir
    • Vitamin B1
    • Vitamin B6
    • Vitamin B12
    • Progesterone
    • Chloramphenicol
    • Erythromycin Salts
    • Neomycin
    • Clindamycin Salts
    • Ornidazole
  • New forces in orbit

    Context

    As it looks at the growing role of the private sector and the effort by nations like the UAE and Luxembourg, Delhi needs to move quickly towards a new model for India’s space activity.

    Growing presence in the outer space

    • Outer space no longer a preserve of a few: When you think of outer space, you think of big powers like the United States, Russia and China.
      • You might also note the collective European effort under the European Space Agency as well as the impressive national space programmes of India and Japan.
      • Strategic or symbol of national pursuit: Space programmes have for long been viewed as either strategic or symbols of national prestige for big countries that are prepared to invest significant resources in the pursuit of a credible presence in outer space.
    • Two small countries challenging the narrative: Two small countries, the United Arab Emirates in the Gulf and the Grand Duchy of Luxembourg in Europe have begun to demonstrate that the outer space need not be the playing ground for big powers alone.
      • Sceptics might think it is pretentious for the UAE with its native population of barely one million and Luxembourg with 600,000 people to think of a place for themselves in space.

    UAE’s presence in the space

    • Reminder for India: The interesting path these two countries have set for themselves in outer space is a reminder that Delhi needs to adapt to the rapidly changing dynamic in outer space.
    • Hope Mars Mission: That size is not a constraint is reflected in the UAE’s plan to launch its Mars mission, “Hope”, later this year in partnership with a range of organisations across the world — including three universities in the US.
      • Japan is scheduled to launch the UAE Mars probe this year.
      • India’s own ISRO is also working with the UAE on its Mars mission.
    • Last year, the first Emirati Astronaut, Hazza al-Mansouri spent more than a week in the US-Russian space station.
    • What are the reasons for the UAE’s space strategy? It is about cornering a slice of the rapidly growing commercial space industry — part of a major effort to diversify the UAE economy away from its reliance on hydrocarbons.

    How Luxembourg is increasing its presence in the outer space

    • Commercial space as a major opportunity: Over the years, Luxembourg moved away from its past reliance on the steel industry to become a centre of European banking and finance.
      • It is now looking at commercial space as a major opportunity.
    • Regulatory steps: Luxembourg has taken a number of regulatory steps to create a vibrant ecosystem for space companies ranging from satellite operations to future extraction of resources from asteroids and other space objects.
    • Expansion of the space sector: At the moment, the space sector accounts for nearly 2 per cent of Luxembourg’s GDP.
      • There are more than 50 companies and two public research organisations that are driving the expansion of space sector in Luxembourg.
      • It entered the space sector only in the middle of the last decade. It is also driven by the need for economic diversification.
    • Leveraging new ideas: UAE and Luxembourg do have a reputation for leveraging new ideas to transcend the limitations of their size in the world.
      • But their space adventure was not possible without the structural changes that are reshaping the global space activity.

    How space industry underwent a change over the years

    • Preserve of national programs: Through the second half of the 20th century, outer space was the sole preserve of national space programmes driven by government-funding, direction and management.
    • The emergence of the private sector: As military uses of space and prestige projects like Moon-landing emerged, major private sector entities already in the aviation industry like Boeing and Lockheed won space contracts in the US.
      • Collaboration with government: The Pentagon and the National Aeronautics and Space Administration (NASA) told these companies what to do.
    • Expansion: The last decades of the 20th century saw significant expansion of satellite-based telecommunication, navigation, broadcasting and mapping, and lent a significant commercial dimension to the space sector.
      • As the digital revolution in the 21st century transformed the world economy, the commercial space sector has begun to grow in leaps and bounds.
      • The global space business is now estimated to be around $ 400 billion and is expected to easily rise to at least trillion dollars by 2040.
    • Rise of SpaceX: One example of the rise of private sector companies in the space sector is SpaceX run by the US entrepreneur Elon Musk.
      • Hired for a resupply mission for the space station, it now launches more rockets every year than NASA.
      • The entry of the private sector has begun to drive down the cost-per-launch through innovations such as reusable rockets.

    Scope of the expansion of the space industry

    • Decrease in launch cost and rise in ambition: As launch costs came down, the private sector has become more ambitious.
      • Internet through space: SpaceX plans to launch hundreds of satellites into the low-earth orbit to provide internet services. Amazon has plans to build a network of more than 3,000 satellites in the low-earth orbit.
      • Space tourism: Musk and Amazon’s Jeff Bezos have plans to develop space tourism and build human settlements on the Moon and on Mars.
      • Small private companies in the fray: It is not just big companies that are aiming for the Moon. Last year, a private company in Israel sent a lunar lander to the Moon. Although the lander crashed, much like India’s Vikram, the private sector has begun to do things that were once the monopoly of national agencies.

    India not in synch with the global changes

    • Not adapting to the change: India, however, is quite some distance away from adapting to the unfolding changes in the global space business.
      • In its early years, India’s space programme that was constrained by lack of resources found innovative ways of getting ahead in space.
    • Space sector dominated by the government: Although the ISRO encourages private sector participation in the national space programme, its model is still very 20th century — in terms of governmental domination.

    Conclusion

    As it looks at the growing role of the private sector and the effort by nations like the UAE and Luxembourg, India needs to move quickly towards a new model for India’s space activity. It needs a regulatory environment that encourages a more dynamic role for the private sector and promotes innovation.