Mother and Child Health – Immunization Program, BPBB, PMJSY, PMMSY, etc.

Ovarian Cancer: Understanding the Silent Killer

Prelims Only | Science Tech | Mains Paper 3: Awareness in various sc and tech fields

Note4Students

From UPSC perspective, the following things are important:

Prelims level: Ovarian Cancer

Why in the News?

In India, Ovarian Cancer ranks among top three cancers affecting women, accounting for 6.6% of all female cancer cases.

- In 2022, India alone reported 47,333 new ovarian cancer cases and 32,978 deaths, emphasizing the critical need for awareness, early detection, and effective treatment.

What is Ovarian Cancer?

	Details
About	Referred to as the “silent killer” due to its subtle symptoms like bloating, pelvic pain, loss of appetite, and frequent urination. Late diagnosis is common.
Common Symptoms	• Bloating • Pelvic/abdominal pain • Loss of appetite • Frequent urination • Indigestion, back pain, fatigue, and weight loss
Cancer Subtypes	• Type I tumours: Less common, early diagnosis, better prognosis • Type II tumours: More common, aggressive, diagnosed at advanced stages
Screening	• No effective screening tests available • CA125 blood test used post-diagnosis but not recommended for routine screening due to limited specificity
Genetic Risk Factors	• Linked to mutations in BRCA1/BRCA2 genes, increasing risk by up to 50% • Genetic testing aids in personalized risk management
Endometriosis	• Associated with a higher risk of certain ovarian cancers, though overall risk remains low
Lifestyle Factors	• Mixed evidence regarding talcum powder usage and its potential link to ovarian cancer • Hair products (dyes, straighteners) may increase risk, though further research is required
HRT & Genetic Counselling	• Hormone replacement therapy (HRT) is linked to a higher risk of ovarian cancer • Genetic counselling helps at-risk individuals with preventive measures

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Indian Army Updates

Exercise Yudh Abhyas, 2024

Prelims Only | Security Issues | Mains Paper 3: Various Security Forces, Agencies & Their Mandates

Note4Students

From UPSC perspective, the following things are important:

Prelims level: Exercise Yudh Abhyas

Why in the News?

The 2024 edition of the India-U.S. Army bilateral exercise Yudh Abhyas has begun at the Mahajan field firing ranges in Rajasthan.
- Concurrently, Phase-II of the Indian Air Force’s (IAF) largest multilateral exercise, Tarang Shakti, is underway in Jodhpur, with eight countries participating, including India.

About Exercise Yudh Abhyas

	Details
Type	Bilateral joint military exercise between India and the United States
Inception Year	2004
Frequency	Annual
Primary Objective	Enhance military cooperation and joint operational capabilities, particularly focusing on counter-terrorism and counter-insurgency operations.
Location	Held alternately in India and the USA
Earlier Edition (2023)	Held at Fort Wainwright, Alaska, focusing on cold-weather operations and high-altitude warfare
Focus	Counter-terrorism operations in semi-desert and desert terrains Urban warfare (FIBUA – Fighting in Built-Up Areas)
Participating Forces in 2024	Indian Army: 600 troops from the RAJPUT Regiment US Army: 1-24 Battalion of the 11th Airborne Division, Alaska
Tactical Drills in 2024	Joint planning sessions Joint responses to terrorist actions Combined field training exercises
Significance	Reflects the growing military partnership between India and the US Enhances interoperability and strengthens strategic defence ties

PYQ:

[2024] Which of the following statements about the Exercise Mitra Shakti-2023 is/ are correct?

This was a joint military exercise between India and Bangladesh.
It commenced in Aundh (Pune).
Joint response during counter-terrorism operations was a goal of this operation.
Indian Air Force was a part of this exercise.

Select the answer using the code given below:

(a) 1, 2 and 3

(b) 1 and 4

(d) 2, 3 and 4

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Air Pollution

India’s first ‘Teal Carbon’ study

Prelims Only | Enviro & Biodiversity | Mains Paper 3: Conservation, Environmental Pollution & Degradation, Eia

Note4Students

From UPSC perspective, the following things are important:

Prelims level: Teal Carbon

Why in the News?

India’s first study on teal carbon was conducted at Keoladeo National Park (KNP) in Rajasthan’s Bharatpur district.

Highlights of the Study

The study at KNP aimed to develop holistic solutions for climate change by understanding the potential of teal carbon in mitigating its effects.
It highlighted that degraded wetlands could release harmful methane and carbon dioxide into the atmosphere, further exacerbating climate challenges.
It suggested the use of biochar, a lightweight black residue comprising carbon and ashes.
- This biochar can help reduce methane discharges and improve wetland conservation.
Specialized instruments like the LI-COR device would be required for real-time measurements of greenhouse gases to further the research.

What is Teal Carbon?

	Details
Definition	Carbon stored in non-tidal freshwater wetlands, including in vegetation, microbial biomass, and organic matter.
Key Sources	Peatlands, freshwater swamps, natural freshwater marshes.
Global Storage	Approximately 500.21 petagrams of carbon (PgC).
Threats	Pollution, land-use changes, water extraction, and degradation of wetlands.
Comparison	Distinct from black and brown carbon, which are produced by incomplete combustion of organic matter.
Benefits of Teal Carbon Ecosystems	Greenhouse gas reduction Increase in groundwater levels Flood mitigation Heat island reduction Urban adaptation
Conservation Importance	Effective conservation of wetlands can enhance teal carbon pools, contributing to climate regulation and environmental sustainability.

PYQ:

[2021] What is blue carbon?

(a) Carbon captured by oceans and coastal ecosystems.

(b) Carbon sequestered in forest biomass and agricultural soils.

(d) Carbon present in atmosphere.

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Innovations in Biotechnology and Medical Sciences

PresVu: India’s First Eye Drop for Presbyopia

Prelims Only | Science Tech | Mains Paper 3: Awareness in various sc and tech fields

Note4Students

From UPSC perspective, the following things are important:

Prelims level: PresVu

Why in the News?

Mumbai-based Entod Pharmaceuticals has announced that the Drug Controller General of India (DCGI) has approved its new eye drop, PresVu, aimed at reducing the dependency on reading glasses for individuals with presbyopia.

What is Presbyopia?

Presbyopia is an age-related condition where the eyes gradually lose the ability to focus on nearby objects, typically developing after the age of 40.
Spectacles are one of the most commonly recommended solutions for managing presbyopia.

How does PresVu work?

The active ingredient in PresVu is pilocarpine, a compound that contracts the iris muscles, controlling the size of the pupil and helping individuals focus better on nearby objects.
PresVu also uses an advanced dynamic buffer technology to adapt to the pH levels of tears, ensuring consistent efficacy and safety for extended use over the years.
However, PresVu’s effects are temporary, typically lasting between four to six hours, and it is prescription-only.

PresVu should not be used by individuals with iris inflammation.
Regular use may lead to side effects such as:
- Itching and redness
- Eyebrow pain
- Muscle spasms in the eyes

Is this a Novel Therapy?

Although Entod claims PresVu is novel, the main compound, pilocarpine, has been available in India for decades and is commonly used as a first-line therapy for cataracts.
Pilocarpine’s ability to temporarily improve the depth of focus has been explored in other countries, including the United States, where the FDA approved a pilocarpine eye drop for presbyopia in 2021.
In India, the government regulates the ceiling price of pilocarpine in 4% and 2% concentrations, whereas PresVu contains 1.25%.

PYQ:

[2018] Appropriate local community-level healthcare intervention is a prerequisite to achieve ‘Health for All’ in India. Explain.

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Goods and Services Tax (GST)

[pib] Recommendations during 54th meeting of GST Council

Prelims Only | Economics | Mains Paper 3: Indian Economy

Note4Students

From UPSC perspective, the following things are important:

Prelims level: 54th meeting of GST Council

Why in the News?

The 54th GST Council meeting, chaired by Union Finance Minister was held recently.

Recommendations from the 54th GST Council Meeting:

GST Rate Changes for Goods
Namkeens and Savory Products	GST on extruded/expanded savoury products reduced from 18% to 12%; 5% GST on un-fried or uncooked snack pellets continues.
Cancer Drugs	GST on cancer drugs like Trastuzumab Deruxtecan, Osimertinib, and Durvalumab reduced from 12% to 5%.
Metal Scrap	Reverse Charge Mechanism (RCM) introduced for metal scrap supplies by unregistered persons; 2% TDS applied on B2B metal scrap supplies by registered persons.
RMPU Air Conditioning Machines	RMPU air conditioning machines for railways classified under HSN 8415, attracting a 28% GST rate.
Car and Motorcycle Seats	GST on car seats (HSN 9401) increased from 18% to 28%, aligning with the rate for motorcycle seats.
GST Rate Changes for Services
Life and Health Insurance	Group of Ministers (GoM) to be constituted to study GST issues related to life and health insurance. Report expected by October 2024.
Transport by Helicopters	GST on passenger transport by helicopters (seat share basis) set at 5%; 18% GST continues for charter helicopter services.
Flying Training Courses	DGCA-approved flying training courses conducted by Flying Training Organizations (FTOs) will be exempt from GST.
Preferential Location Charges	Preferential Location Charges (PLC) in construction services to be taxed as composite supply.
Affiliation Services	Affiliation services provided by boards like CBSE taxable; services provided to government schools by state/central boards will be exempt.
Import of Services by Branches	Import of services by foreign airlines’ branch offices from related persons will be exempt from GST if made without consideration.
Compliance Measures
B2C E-invoicing	Pilot project for B2C e-invoicing introduced to improve business efficiency and environmental sustainability.
Invoice Management System (IMS)	Invoice Management System to allow taxpayers to accept, reject, or keep invoices pending for claiming Input Tax Credit (ITC).
Waiver of Interest/Penalty	Special procedure to waive interest/penalty for tax demands from FY 2017-18, 2018-19, and 2019-20 under section 73 of CGST Act.
Clarifications via Circulars	Clarifications on place of supply for advertising services, ITC on demo vehicles, and place of supply for data hosting services to be issued.

PYQ:

[2018] Consider the following items:

1. Cereal grains hulled

2. Chicken eggs cooked

3. Fish processed and canned

4. Newspapers containing advertising material

Which of the above items is/are exempted under GST (Goods and Services Tax)?

(a) 1 only

(b) 2 and 3 only

(d) 1, 2, 3 and 4

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International Space Agencies – Missions and Discoveries

BepiColombo Mission

Prelims Only | | Mains Paper 3: Awareness in various sc and tech fields

Note4Students

From UPSC perspective, the following things are important:

Prelims level: BepiColombo Mission

BepiColombo

Why in the News?

On Thursday, the ESA-Japan spacecraft “BepiColombo” made its closest approach to Mercury, capturing detailed images of its sunrise-lit surface and revealing the planet’s south pole.

Highlights of the Latest Flyby:

- BepiColombo uses flybys of Earth, Venus, and Mercury to slow down and enter orbit around Mercury. This approach gives scientists new information about Mercury’s south pole and its unusual peak ring craters, which haven’t been studied much before.
Note: Flybys are close passes of a spacecraft near a planet or celestial body

About BepiColombo Mission:

	Details
Collaboration	European Space Agency (ESA) and Japan Aerospace Exploration Agency (JAXA)
Launch Date	October 20, 2018 Expected to enter Mercury’s orbit by late 2026.
Launch Vehicle	Ariane 5 Rocket
Objectives	Study Mercury’s magnetic field Investigate surface composition and geology Analyze Mercury’s interaction with solar wind Study exosphere and geological history
Spacecraft Components	ESA’s Mercury Planetary Orbiter (MPO): Focus on surface and interior study JAXA’s Mercury Magnetospheric Orbiter (MIO): Focus on magnetic field and surrounding space
Planned Flybys	6 (Flybys of Earth, Venus, and Mercury) Ongoing, with 4 out of 6 Mercury flybys completed
Craters Studied	Vivaldi Crater, Stoddart Crater
Significance	Second mission ever to orbit Mercury (after NASA’s Messenger, 2004)
Challenges	Mercury’s proximity to the Sun accelerates spacecraft, requiring multiple flybys to slow down Thruster issues causing mission delay

PYQ:

[2008] What is the purpose of the US Space Agency’s Themis Mission, which was recently in the news?

(a) To study the possibility of life on Mars.

(b) To study the satellites of Saturn.

(d) To build a space laboratory to study the stellar explosions.

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International Space Agencies – Missions and Discoveries

What is Helium and why is it used in Rockets?

Prelims Only | Science Tech | Mains Paper 3: Awareness in various sc and tech fields

Note4Students

From UPSC perspective, the following things are important:

Prelims level: Helium

Why in the News?

Two NASA astronauts aboard Boeing’s Starliner will remain on the International Space Station (ISS) for an extended period due to issues with a faulty propulsion system, including helium leaks.

helium

About Helium

Helium is inert, meaning it does not react or combust when exposed to other substances.
This makes it ideal for pressurization and cooling systems in rockets and spacecraft.
With an atomic number of 2, Helium is second lightest element after hydrogen, helping to keep the rocket’s weight low, which is crucial for achieving the necessary speeds and altitudes to reach orbit.
It has an extremely low boiling point (-268.9°C), allowing it to stay in a gaseous state in super-cold environments, where many rocket fuels are stored.
Though non-toxic, helium cannot be inhaled on its own as it displaces oxygen, which is vital for human respiration.

How is Helium used for space applications?

Fuel Tank Pressurization: Helium pressurizes fuel tanks, ensuring a consistent flow of fuel to the rocket’s engines, even as the fuel is burned.
Cooling Systems: It also plays a key role in cooling systems, particularly in environments where rocket fuel and oxidizer need to be stored at extremely low temperatures.
Maintaining Tank Pressure: As fuel and oxidizer are consumed, helium fills the empty space left behind, ensuring the overall pressure inside the tanks remains stable.

Is Helium prone to leaks?

Helium’s small atomic size and low molecular weight make it prone to leaking through tiny gaps or seals in storage tanks and fuel systems.
Since helium is rare in Earth’s atmosphere, even minor leaks are easily detectable, making it a valuable tool for spotting potential faults in spacecraft fuel systems.

Examples of Leaks:

- In May, hours before Boeing’s Starliner spacecraft attempted its first astronaut launch, sensors detected a small helium leak in one of its thrusters.
- After Starliner launched in June, additional leaks were found in space, prompting NASA to return the spacecraft to Earth without its crew.

Alternatives to Helium

Argon and Nitrogen: Some rocket launches have experimented with other inert gases like argon and nitrogen, which are sometimes cheaper, but helium remains the industry standard.
Ariane 6’s Novel System: Europe’s new Ariane 6 rocket abandoned helium in favor of a pressurization system that converts small amounts of its liquid oxygen and hydrogen into gas for pressurizing the fuel.
- However, during Ariane 6’s debut launch, this system failed in space, adding to the global rocket industry’s pressurization challenges.

PYQ:

[2012] A team of scientists at Brookhaven National Laboratory included those from India created the heaviest anti-matter (anti-helium nucleus). What is/are the implication/implications of the creation of anti-matter?

1. It will make mineral prospecting and oil exploration easier and cheaper.

2. It will help prove the possibility of the existence of stars and galaxies made of anti-matter.

3. It will help understand the evolution of the universe.

Select the correct answer using the codes given below:

(a) 1 only

(b) 2 and 3 only

(d) 1, 2 and 3

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International Space Agencies – Missions and Discoveries

What is the Principle of Planetary Protection?

Prelims Only | Science Tech | Mains Paper 3: Awareness in various sc and tech fields

Note4Students

From UPSC perspective, the following things are important:

Prelims level: Principle of Planetary Protection

Why in the News?

Planetary protection is a crucial principle in space missions that travel from Earth to other planetary bodies, such as the Moon or Mars.
- The goal is to preserve both Earth’s biosphere and the planetary body’s environment from contamination by alien microbial life.

About Planetary Protection:

	Details
Definition	Safeguarding Earth’s biosphere and other planetary bodies from microbial contamination during space missions.
Objective	Prevent contamination of Earth’s environment and other planets by alien microbes or Earth-origin microorganisms.
Legal Basis	Article IX of Outer Space Treaty (1967) mandates avoiding harmful contamination in space exploration.
Importance	Protects integrity of scientific research on other planets. Prevents potential biological threats to Earth.
Methods of Implementation	Spacecraft sterilization (e.g. baking in a dry room at 120°C for 3 days). Planning missions to avoid cross-contamination.
Key Applications	Missions to Mars, Moon, Europa and other celestial bodies where contamination may disrupt research or pose risks.
Challenges	Increased costs and technical demands for maintaining sterile spacecraft and environments.
Recent Example	China’s Tianwen-3 Mars sample-return mission (2028) confirmed adherence to planetary protection principles.
Global Cooperation	International space agencies follow planetary protection guidelines for sustainable and safe space exploration.

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Land Reforms

Enemy Properties in India

Prelims Only | Governance | Mains Paper 2: Government Scheme/Policies

Note4Students

From UPSC perspective, the following things are important:

Prelims level: Enemy Property Act, 1968

Why in the News?

The Union Home Affairs Ministry has notified the auction of land in Uttar Pradesh previously owned by the family of former Pakistan President Pervez Musharraf.

Enemy Properties in India

	Details
Definition	Assets (movable and immovable) and properties of individuals or entities from countries at war with India, vested with CEPI.
History	Concept initiated after India-Pakistan wars (1965 & 1971) and the 1962 Sino-Indian war.
Legislation	Enemy Property Act, 1968; Enemy Property (Amendment and Validation) Act, 2017.
Custodian	Custodian of Enemy Property for India (CEPI), under the Ministry of Home Affairs.
Total such Properties	12,611 enemy properties; 12,485 from Pakistani nationals, 126 from Chinese citizens.
States with Highest Properties	Uttar Pradesh (6,255), followed by West Bengal, Delhi, Goa, Maharashtra, and Telangana.
Movable Assets	Includes shares, gold, etc. Government has earned over ₹3,400 crore from the disposal of these assets.
Immovable Properties	No immovable enemy property has been sold so far.
Significant Court Cases
Raja of Mahmudabad Case (2005)	Supreme Court ruled in favor of the son of the Raja, allowing him to claim enemy properties. This led to multiple claims by heirs.
2010 Ordinance	In response to the 2005 judgment, the government issued an ordinance to prevent the transfer of enemy properties to legal heirs.
2016 Amendment & Ordinance	The 2016 Enemy Property (Amendment and Validation) Ordinance nullified previous court orders, ensuring enemy properties remain with the Custodian.

PYQ:

[2017] With reference to the ‘Prohibition of Benami Property Transactions Act, 1988 (PBPT Act)’, consider the following statements:

1. A property transaction is not treated as a benami transaction if the owner of the property is not aware of the transaction.

2. Properties held benami are liable for confiscation by the Government.

3. The Act provides for three authorities for investigations but does not provide for any appellate mechanism.

Which of the statements given above is/are correct?

(a) 1 only

(b) 2 only

(d) 2 and 3 only

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Tiger Conservation Efforts – Project Tiger, etc.

National Tiger Conservation Authority (NTCA)

Prelims Only | Enviro & Biodiversity | Mains Paper 3: Conservation, Environmental Pollution & Degradation, Eia

Note4Students

From UPSC perspective, the following things are important:

Prelims level: NTCA

Why in the News?

The National Tiger Conservation Authority (NTCA), the apex body responsible for tiger conservation, recently issued directives urging 19 States to prioritize the relocation of villagers residing in core tiger zones.

NTCA’s Directive:

According to the NTCA, 591 villages, comprising 64,801 families, reside in the core tiger zone, posing a significant concern for tiger conservation.
The core zone refers to the part of a tiger reserve where human activities such as hunting and forest produce collection are PROHIBITED, and tribals CANNOT reside.
- Outside the core zone is the buffer zone, where certain activities are allowed but regulated.

About National Tiger Conservation Authority (NTCA):

	Details
Constitution	Statutory body under MoEFCC, constituted under Wildlife (Protection) Act, 1972.
Chairmanship	Chaired by the Minister for Environment and Forests.
Structure	• 8 experts in wildlife conservation and tribal welfare. • 3 MPs. • Inspector General of Forests as ex-officio Member Secretary.
Objectives	• Provide statutory authority to Project Tiger. • Enhance Centre-State accountability in managing Tiger Reserves. • Provide parliamentary oversight. • Address livelihood concerns of local communities.
Powers and Functions	• Approve state-prepared tiger conservation plans. • Prevent unsustainable land use in Tiger Reserves. • Set standards for tourism and tiger conservation guidelines. • Conduct tiger censuses (via M-STrIPES app). • Support biodiversity conservation through eco-development and people’s participation.
Key Initiative	• Project Tiger, a Centrally Sponsored Scheme for in-situ conservation of tigers, launched on April 1, 1973.

PYQ:

[2014] Consider the following statements:

1. Animal Welfare Board of India is established under the Environment (Protection) Act, 1986.

2. National Tiger Conservation Authority is a statutory body.

3. National Ganga River Basin Authority is chaired by the Prime Minister.

Which of the statements given above is/ are correct?

(a) 1 only

(b) 2 and 3 only

(d)1, 2 and 3

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Type: Prelims Only

Why in the News?

What is Ovarian Cancer?

Why in the News?

About Exercise Yudh Abhyas

PYQ:

Why in the News?

Highlights of the Study

What is Teal Carbon?

PYQ:

Why in the News?

What is Presbyopia?

How does PresVu work?

Is this a Novel Therapy?

PYQ:

Why in the News?

Recommendations from the 54th GST Council Meeting:

GST Rate Changes for Goods

GST Rate Changes for Services

Compliance Measures

PYQ:

Why in the News?

Highlights of the Latest Flyby:

About BepiColombo Mission:

PYQ:

Why in the News?

About Helium

How is Helium used for space applications?

Is Helium prone to leaks?

Alternatives to Helium

PYQ:

Why in the News?

About Planetary Protection:

Why in the News?

Enemy Properties in India

Significant Court Cases

PYQ:

Why in the News?

NTCA’s Directive:

About National Tiger Conservation Authority (NTCA):

PYQ: