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GS Paper: GS3-15.Science and Technology- Developments and their Applications and Effects in Everyday Life.

  • Conflict of Interest in the RDI Fund: When Proximity Is the Qualification

    Why in the News

    The Union Minister for Science and Technology has described the conflict of interest safeguards governing the Research, Development and Innovation Fund as fairly robust, and said more safeguards could be considered wherever feasible. The remarks follow a disclosure that most companies funded in the Fund’s first round had investment ties to members of the panel that selected them.

    What is the Research, Development and Innovation Fund and what does it finance?

    1. A public financing vehicle for frontier research: The Research, Development and Innovation (RDI) Fund was set up by the government last year to give low cost, long tenure loans to private companies doing cutting edge research.
    2. Priority areas named at launch: Eligible fields include quantum computing, robotics, space, biotechnology, clean energy and climate action.
    3. Corpus and horizon: The Fund is to carry a corpus of Rs 1 lakh crore built over six years.
    4. Instruments used: Money moves out as low interest loans, as equity, or as contributions to a fund of funds, not as a research grant.

    Why is the Fund built as a repayable capital instrument rather than a research grant?

    1. A revolving fund, not a one time outlay: The RDI Special Financial Rules provide for recycling of capital and its return to the Consolidated Fund of India. That makes it a revolving innovation fund rather than a spending line exhausted once disbursed.
    2. Co-financing ceiling: A selected company can draw a maximum of 50 percent of its project cost from the Fund. The remainder comes from the promoter and private investors, giving both a stake in the outcome.
    3. Risk reduced by portfolio and stage selection: Companies are chosen after their core technology risk has been overcome. The portfolio approach spreads residual risk across ventures rather than concentrating it in one bet.
    4. A shift in the state’s role: Public support moves away from the traditional grant model for research. The government now sets the strategic direction of technological progress and mobilises industry expertise and private capital alongside its own money.
    5. The bottleneck it targets: Government financing of high technology firms has been held back by cumbersome processes and by gaps in technical knowledge inside the bureaucracy.

    What conflict of interest architecture did the Fund already carry?

    1. Committee composition is mandated, not incidental: The scheme requires the Expert Advisory Committee to be composed of eminent industry leaders drawn from industry, investment or technology research and development sectors.
    2. Mandatory recusal: A committee member holding a stake in an applicant must declare that interest and step out of the evaluation of that applicant.
    3. Supermajority voting: The choice of an investee company requires a supermajority of the committee rather than a simple majority.
    4. Recommendation separated from decision: The Investment Committee is a recommending body only. Final accountability for a funding decision rests with the Technology Development Board.
    5. Guidelines framed in anticipation: These pre-investment rules were written in the expectation that connections between industry experts and applicants would be unavoidable.

    What did the first round of disbursement expose about that architecture?

    1. First round approvals: Loans worth Rs 2,192 crore were approved for 22 companies in the first round of funding.
    2. Extent of the overlap: Fifteen of those 22 companies had investment ties to seven members of the selection panel.
    3. The stated procedure was followed: The members concerned declared their interest and recused themselves in each such case, as the guidelines require.
    4. A different pattern in the second round: Only one of the 13 companies selected in the second round has any link to a member of the selection committee. That selection has been finalised and has not been disclosed.
    5. The question the overlap raised: A safeguard that operated correctly in every individual case still left most of the first round money going to companies connected to the panel.

    Is proximity between evaluators and investees a defect or a necessary input?

    1. Proximity as an information input: Not all proximity is conflicting where it improves the quality of the decision. Deep technology investment needs judgement that combines technological maturity with commercial viability.
    2. Who else could supply that judgement: Neither government officials nor academic and scientific evaluators alone can assess whether a frontier technology is ready to be sold.
    3. The connections are the qualification: The members are industry veterans who built and engaged deeply with India’s technology ecosystem. Their investee links are the same links that let them bridge the information gap in screening.
    4. The linkage data read the other way: At least 10 of the 15 startups publicly named have institutional or founder linkages to publicly funded premier technology institutions such as the Indian Institutes of Technology (IITs). Most had already raised external funding, which signals an independent assessment of their technical merit.
    5. The wrong yardstick: The Fund is a public capital deployment mechanism, not a public expenditure scheme. Judging it by the procedural propriety standards written for conventional bureaucratic spending misreads what it is, and outcomes plus the effectiveness of its governance architecture are the better test.
    6. The cost of over correction: Parliamentary and media scrutiny is essential for political accountability. Scrutiny that stifles the scheme damages an instrument on which India’s growth prospects rest.

    Why does India’s scale-up gap make the Fund’s design consequential?

    1. A decade of Startup India: Startup registrations have burgeoned since the programme began, and the entrepreneurial ecosystem has come a long way with them.
    2. The gap that remains: India has not produced many high impact global scale-ups, particularly in technology intensive sectors.
    3. What the Fund is aimed at: The RDI Fund is targeted at closing that gap in frontier sectors, not at early stage startup formation.
    4. Public money as a catalyst: Sectoral commitments by the government pull private investment into technology areas where mission mode initiatives already exist.
    5. The strategic stake: Capability in frontier technology bears directly on technological sovereignty and strategic autonomy.

    What is the government now changing in the Fund’s framework?

    1. The stated position on safeguards: The existing safeguards against conflict of interest in disbursement are held to be fairly robust, with more safeguards to be considered wherever feasible.
    2. A full procedural review: Every procedural safeguard in use against a conflict of interest situation was reviewed at the monthly meeting of secretaries of scientific departments.
    3. Due diligence held as non negotiable: Due diligence and verification processes must remain uncompromised, and suggestions from stakeholders are invited.
    4. Wider sectoral eligibility: Companies from many more sectors have been made eligible for loans, following a recommendation by an expert committee.
    5. Ministries asked to nominate areas: Inter-ministerial consultations have taken place, and every ministry has been asked to suggest areas of national importance where private research could be supported.
    6. Learning carried into later rounds: The experience of the first round is expected to make subsequent rounds function more smoothly and more efficiently.
    7. The balance the government names: Private sector participation inside a public funding framework is treated as a new experience that requires a balance between speed, responsibility and stakeholder confidence.

    Challenges to the Research, Development and Innovation Fund

    1. Concentration of capital in already backed firms: Selecting ventures whose technology risk is retired favours firms with prior institutional and investor backing over first time deep technology founders. e.g. under the Production Linked Incentive scheme for large scale electronics manufacturing, most approved incentive has flowed to a small group of mobile phone assemblers.
    2. Repayment mismatch in long gestation science: Loan repayment schedules sit poorly with fields where commercial revenue arrives a decade or more after the first working prototype. e.g. quantum computing, a stated priority area, has no volume hardware market anywhere in the world.
    3. No statutory conflict of interest code for non official members: The safeguards rest on scheme guidelines rather than on a binding statute, so a lapse carries no legal consequence. e.g. the 2024 controversy over the Securities and Exchange Board of India chairperson’s disclosed holdings ended in fresh internal disclosure norms and no statutory remedy.
    4. Thin domestic risk capital for follow on rounds: A public loan cannot substitute for the later stage private rounds a hardware venture needs to reach scale. e.g. Indian fabless semiconductor design ventures raise most of their growth capital from overseas funds.
    5. Eligibility drift diluting the frontier focus: Widening the eligible sector list risks turning a frontier technology instrument into a general industrial credit line. e.g. startup recognition under the Department for Promotion of Industry and Internal Trade expanded to cover trading and service ventures far removed from technology development.
    6. Propriety scrutiny slowing deployment: A financing vehicle under continuous propriety examination becomes defensive and slow, defeating the speed it was built for. e.g. the National Investment and Infrastructure Fund, announced in 2015, took several years to move from announcement to meaningful deployment.

    Conclusion

    The RDI Fund was designed to bring investor judgement into a public financing decision. The conflict of interest it now faces is the direct cost of that design choice. Recusal and voting thresholds manage the appearance of the problem without removing the overlap between those competent to evaluate deep technology and those already invested in it. What remains unsettled is whether a capital deployment vehicle will be judged on the technologies and returns it produces or on the procedural standards written for ordinary government spending.

    Matching Previous Year Question

    [2018, GS4, 10 marks] What is meant by conflict of interest? Illustrate with examples, the difference between the actual and potential conflicts of interest.

    [2014, GS3, 12.5 marks] Scientific research in Indian universities is declining, because a career in science is not as attractive as our business operations, engineering or administration, and the universities are becoming consume

  • Navy to lease two new MQ-9B Sea Guardian unmanned aircraft from US firm

    Why in the News

    The Ministry of Defence (MoD) signed a ₹1,943 crore contract with General Atomics Aeronautical Systems Inc. (GA-ASI) to lease two MQ-9B Sea Guardian aircraft to the Indian Navy for 30 months. This will increase the Navy’s leased HALE RPAS fleet from 2 to 4, enabling simultaneous surveillance of India’s eastern and western seaboards.

    What is MQ-9B Sea Guardian?

    • HALE: High Altitude Long Endurance
    • RPAS: Remotely Piloted Aircraft System
    • Maritime variant of the MQ-9B family.
    • Provides persistent ISR (Intelligence, Surveillance and Reconnaissance) over large maritime areas.
    • Equipped with advanced sensors and surveillance payloads.
    • Can also undertake precision strikes.
    • Strengthens MDA (Maritime Domain Awareness) in the Indian Ocean Region.

    Key Concepts

    Maritime Domain Awareness (MDA)

    • Understanding activities in the maritime environment affecting security, safety, economy and marine environment.
    • It integrates: Radar, Satellites, Coastal surveillance, AIS (Automatic Identification System), and Airborne sensors

    HALE RPAS

    • An unmanned aircraft operated remotely from a ground control station.
      • High altitude: Wider sensor coverage.
      • Long endurance: Prolonged surveillance with fewer interruptions.

    Why is India Leasing MQ-9Bs?

    • Bridges the surveillance gap until the 31 purchased MQ-9Bs are delivered.
    • Provides immediate long endurance maritime surveillance.
    • Allows crews and maintainers to gain experience with a configuration similar to the future fleet.
    • Builds on the Navy’s existing experience with leased MQ-9As since 2020.

    How Does It Strengthen the Navy?

    • HALE systems increase from 2 to 4.
    • Enables simultaneous surveillance of eastern and western maritime regions.
    • Improves persistent monitoring of the Indian Ocean Region (IOR).
    • Strengthens early detection and response to maritime threats.

    2024 India-US MQ-9B Agreement

    • 31 MQ-9B systems for India’s armed forces.
    • Approximate value: $3.5 billion.
    • Includes a Global MRO (Maintenance, Repair and Overhaul) facility in India.
    • Provides for some assembly in India.
    • Includes indigenous sourcing of components.
    • Supports defence indigenisation and domestic manufacturing.

    [2025] With reference to Unmanned Aerial Vehicles (UAVs), consider the following statements:
    I. All types of UAVs can do vertical landing.
    II. All types of UAVs can do automated hovering.
    III. All types of UAVs can use battery only as a source of power supply.
    Which of the statements given above are correct?
    (a) Only one
    (b) Only two
    (c) All the three
    (d) None

  • Can a 100-Year-Old Vaccine Train the Brain’s Immune System?

    Why in the News

    A study gave two doses of the Bacillus Calmette Guerin vaccine a month apart to 23 older adults and tracked blood and cerebrospinal fluid for a year, finding monocytes switching on genes for a faster immune response. This is evidence of trained immunity operating within the central nervous system. The tension is between a cheap, decades old vaccine with a large safety record and a study too small to establish clinical benefit.

    Note: Bacillus Calmette-Guérin (BCG) vaccine is more than 100 years old. It was first given to a human on July 18, 1921. Two French scientists, Albert Calmette and Camille Guérin, made the vaccine to stop tuberculosis (TB).

    What is trained immunity?

    1. About: Trained immunity is the capacity of innate immune cells to mount a stronger response to a later, unrelated challenge after an initial exposure, through lasting changes in gene expression.
    2. How it differs from adaptive immunity: Adaptive immunity is pathogen specific and mediated by lymphocytes. Trained immunity is non specific and mediated by innate cells such as monocytes.
    3. Mechanism: The change operates through epigenetic and metabolic reprogramming rather than through antibody memory.
    4. Why BCG: BCG is the best documented inducer of trained immunity, which is why it is used to test the effect.

    What did the study actually find?

    1. Sample and design: 23 older adults were enrolled, roughly half with cerebrospinal fluid biomarkers of Alzheimer’s disease, given two BCG doses a month apart.
    2. Immune change: Monocytes switched on genes associated with a faster immune response.
    3. Functional test: Monocytes responded more strongly to lipopolysaccharide, a standard bacterial stimulus, confirming a functional and not merely transcriptional change.
    4. Amyloid movement: Amyloid fell in cerebrospinal fluid and rose in blood among participants without established Alzheimer’s, and not among those with it.
    5. Location of the effect: The change was detected in the central nervous system compartment, which is the finding’s principal claim.

    What are the study’s stated limits?

    1. Sample size: 23 participants is too small to detect a clinical effect.
    2. No control arm: The study had no placebo group, so observed changes cannot be separated from natural variation.
    3. No cognitive change: Cognitive scores were unchanged over the year.
    4. Directional ambiguity: Amyloid shifting from cerebrospinal fluid to blood is consistent with clearance and is not proof of clearance.

    Why does a cheap vaccine matter for this disease?

    1. Cost comparison: BCG is inexpensive and carries decades of safety data, against anti amyloid drugs that are expensive and require infusion infrastructure.
    2. Existing supply: BCG is already manufactured at scale for tuberculosis immunisation.
    3. Repurposing precedent: A five year BCG cohort in type 1 diabetes established the model of testing the vaccine for a non tuberculosis indication.
    4. Underlying hypothesis: Chronic low grade inflammation with ageing, described as inflammaging, is implicated in neurodegeneration, and trained immunity is one route to modulating it.

    Challenges in translating this finding

    1. Blood brain barrier access: Demonstrating that a peripheral vaccine changes central nervous system immunity requires invasive sampling. e.g. the cerebrospinal fluid collection this study depended on.
    2. Amyloid hypothesis contestation: Amyloid reduction has not reliably produced cognitive benefit. e.g. the modest clinical effect sizes reported for approved anti amyloid antibodies.
    3. Trial duration: Neurodegeneration progresses over years, so trials must run long. e.g. the five year design of the BCG type 1 diabetes cohort.
    4. Vaccine supply competition: Diverting BCG to a new indication competes with tuberculosis immunisation demand. e.g. periodic global BCG supply shortages affecting national immunisation programmes.
    5. Strain variability: BCG substrains differ in immunological potency, complicating replication. e.g. the differing efficacy estimates across BCG trials attributed to substrain variation.
    6. Diagnostic access: Identifying preclinical Alzheimer’s requires biomarker testing unavailable at scale in India. e.g. limited availability of cerebrospinal fluid and amyloid imaging assays outside tertiary centres.

    Conclusion

    The study’s contribution is the demonstration that trained immunity can be detected within the central nervous system, which extends a peripheral immunology concept into neurology. It establishes a mechanism, not a treatment, since 23 participants without a control arm and with unchanged cognition cannot support a clinical claim. The next milestone is a randomised controlled trial with a placebo arm and cognitive endpoints over a multi year horizon.

    Back2Basics: Bacillus Calmette Guerin vaccine

    1. A live attenuated vaccine derived from Mycobacterium bovis, first administered in humans in 1921.
    2. Used primarily against severe childhood forms of tuberculosis, including tuberculous meningitis and miliary tuberculosis.
    3. Included in India’s Universal Immunisation Programme, given at birth or as early as possible thereafter.
    4. Provides limited protection against pulmonary tuberculosis in adults, which is why a new tuberculosis vaccine remains a research priority.
    5. Also used as an intravesical immunotherapy for non muscle invasive bladder cancer.
    6. Manufactured in India at the BCG Vaccine Laboratory, Chennai, among other facilities.

    Government Initiatives

    1. National Tuberculosis Elimination Programme: Targets tuberculosis elimination, covering diagnosis, treatment and nutritional support for patients.
    2. Ni-kshay Poshan Yojana: Provides direct benefit transfer for nutritional support to tuberculosis patients on treatment.
    3. Universal Immunisation Programme: Provides BCG and other vaccines free of cost, targeting infants and pregnant women.
    4. National Programme for Health Care of the Elderly: Provides dedicated geriatric health services including cognitive and mental health care.
    5. Indian Council of Medical Research clinical trial network: Supports multicentre trials, including for tuberculosis vaccine candidates.

    Way Forward

    1. Run a controlled trial: Replicate the finding with a placebo arm and a sample large enough to detect a cognitive effect.
    2. Standardise the substrain: Fix the BCG substrain across trial sites so results are comparable.
    3. Protect immunisation supply: Ensure any repurposing trial does not draw on doses allocated to childhood tuberculosis immunisation.
    4. Expand biomarker capacity: Build cerebrospinal fluid and blood biomarker testing capacity so preclinical cases can be identified for trial enrolment.
    5. Fund domestic replication: Support an Indian cohort, since India carries both the largest BCG immunised population and a rapidly ageing one.

    “[2022, GS3, 15 marks] What is the basic principle behind vaccine development? How do vaccines work? What approaches were adopted by the Indian vaccine manufacturers to produce COVID-19 vaccines?”

  • The missing ‘reuse’ principle in India’s EV transition journey

    Why in the News?

    India’s electric mobility transition is gathering momentum as adoption rises and circular economy principles enter industrial policy. India’s policy has advanced the recycling tier of circularity through scrappage but neglected the higher priority reuse tier, exposing a gap where structurally sound vehicles are scrapped rather than retrofitted.

    What is the circular economy hierarchy?

    1. Definition: The circular economy is built on a hierarchy that prioritises reducing resource consumption, then reusing existing assets, and only recycling materials once products have genuinely reached the end of their useful life.
    2. Reuse versus recycle: Recycling recovers materials after a product becomes waste, while reuse preserves functionality before the asset becomes waste. Reuse sits higher in the hierarchy.

    What is vehicle retrofitment?

    1. What it is: Retrofitment replaces the internal combustion engine, fuel system, and related components of an existing vehicle with an electric powertrain, while retaining the core vehicle structure.
    2. Why it counts as reuse: By keeping a structurally sound chassis and body in service, it preserves and extends the value already embedded in the asset rather than recovering value only after the vehicle becomes waste.

    How far has India progressed on recycling?

    1. Rules framework: The Motor Vehicles (Registration and Functions of Vehicle Scrapping Facility) Rules, 2021, and the Environment Protection (End of Life Vehicles) Rules, 2025, strengthened responsible vehicle recycling and material recovery.
    2. Facilities on ground: As of January 2026, 129 Registered Vehicle Scrapping Facilities were operational across 21 States and Union Territories.
    3. Vehicles processed: About 4.3 lakh vehicles had been processed through these facilities, building a formal ecosystem for recycling and resource recovery.

    Why does retrofitment matter?

    1. Per vehicle waste: A single two wheeler generates approximately 90 kilograms of recyclable material and 18 kilograms of landfill waste when scrapped.
    2. Fleet scale burden: Scaled across India’s fleet of about 30 crore vehicles, a scrap first approach would generate 2.7 crore tonnes of recyclable material and 0.54 crore tonnes of landfill waste.
    3. SDG alignment: Retrofitment supports United Nations Sustainable Development Goal 12 on responsible consumption and production by reducing material demand and waste.
    4. Old but sound: A vehicle can be old yet retain a strong chassis, intact body, and years of service life, making retrofitting more circular than scrapping.

    What is the three pathway vehicle hierarchy?

    1. First pathway, continued use: Vehicles that remain safe, compliant, and efficient should keep operating with routine maintenance, since age alone should not trigger removal.
    2. Second pathway, retrofitment: Vehicles with sound structure but ageing or polluting powertrains can be converted to electric through certified processes, extending life while cutting emissions.
    3. Third pathway, scrappage: Vehicles with compromised safety, severe structural degradation, accident damage, or significant corrosion proceed to scrappage and recycling.

    The missing middle path

    1. Not a competition: Retrofitment is not a competing strategy to scrappage but the missing middle path that policy has not focused on yet.
    2. Condition over age: Treating every ageing vehicle as a disposal candidate overlooks the chance to extend asset life while accelerating electrification.
    3. Public acceptance: A condition assessed transition would make scrappage more acceptable, as citizens would see that older vehicles are assessed for transformation rather than dismissed indiscriminately.

    What are the challenges to a reuse led EV transition?

    1. Certification gap: Retrofitment needs robust certified conversion technology and testing standards to ensure safety.
    2. Cost and financing: Conversion costs can rival buying a new two wheeler, limiting uptake without incentives.
    3. Battery supply dependence: Electric powertrains depend on imported cells and critical minerals, a supply chain vulnerability.
    4. Policy bias toward scrappage: Existing incentives favour scrappage and new vehicle purchase, leaving reuse unsupported.
    5. Skilled workforce shortage: A trained network of certified retrofit workshops is largely absent at scale.
    6. End of life battery waste: Retrofitted vehicles eventually generate battery waste requiring recycling infrastructure.

    Conclusion

    India’s transport transition is a question of resource efficiency, not a contest between new electric vehicles and older ones. Adopting an age assessed pathway that distinguishes continued use, retrofitment, and scrappage would align the transition with genuine circular economy principles. This would prevent waste before it is created and confine recycling to vehicles that have truly reached the end of their useful life.

    What is Circular Economy? (Foundational Context)

    1. About: A circular economy keeps materials and products in use for as long as possible, extracting maximum value before recovery and regeneration, in contrast to the linear take, make, dispose model.
    2. Rationale: It exists to cut resource extraction, greenhouse gas emissions, and waste while sustaining economic value.
    3. Named hierarchy: It rests on reduce, reuse, and recycle in that order of priority, with reduce and reuse ranked above recycling.

    Key Concerns Regarding the Circular Economy

    1. Recycling bias: Policy attention concentrates on recycling while the higher value reduce and reuse tiers are neglected.
    2. Informal sector dominance: Much recycling occurs in the informal sector with poor environmental and safety standards.
    3. Extended producer responsibility gaps: Enforcement of producer take back obligations remains weak.
    4. Data deficits: Weak material flow data limits measurement of circularity outcomes.

    Back2Basics: Sustainable Development Goal 12

    1. What it is: SDG 12 is the goal on responsible consumption and production within the 2030 Agenda for Sustainable Development.
    2. Adopted: It was adopted by United Nations member states in 2015.
    3. Focus: It targets sustainable consumption patterns, resource efficiency, and reduced waste generation.
    4. Relevance: Vehicle retrofitment directly advances its call for better resource efficiency and reduced waste.

    Government Initiatives for EVs and Circularity

    1. PM E-DRIVE Scheme: Provides demand incentives for electric two and three wheelers and other electric vehicles.
    2. FAME India Scheme: Faster Adoption and Manufacturing of Electric Vehicles, supporting demand and charging infrastructure.
    3. Vehicle Scrappage Policy: Encourages phasing out of unfit and polluting vehicles through registered scrapping facilities.
    4. Battery Waste Management Rules, 2022: Mandate extended producer responsibility for battery recycling.
    5. PLI schemes: Production Linked Incentives for advanced chemistry cell batteries and automobiles.

    Way Forward

    1. National vehicle hierarchy: Adopt a framework treating vehicles by condition rather than age alone.
    2. Certified retrofit ecosystem: Standardise conversion technology and expand certified workshops.
    3. Incentivise reuse: Extend fiscal support to retrofitment on par with scrappage and new purchase.
    4. Strengthen battery circularity: Build reverse logistics and recycling for end of life batteries.
    5. Skilling: Train technicians for certified electric powertrain conversion.

    “[2025] Consider the following statements:

    Statement I: Circular economy reduces the emissions of greenhouse gases.

    Statement II: Circular economy reduces the use of raw materials as inputs. Statement III: Circular economy reduces wastage in the production process.

    Which one of the following is correct in respect of the above statements?

    (a) Both Statement II and Statement III are correct and both of them explain Statement I

    (b) Both Statement I and Statement II are correct and Statement I explains Statement II

    (c) Only one of the Statements II and III is correct and that explains Statement I

    (d) Neither Statement II nor Statement III is correct

    Question (2023, GS3): “The adoption of electric vehicles is rapidly growing worldwide. How do electric vehicles contribute to reducing carbon emissions and what are the key benefits they offer compared to traditional combustion engine vehicles?

  • Conflict of interest surfaces in the Rs 1 lakh crore RDI Fund

    Why in the News

    An investigation found that a large share of soft loans under the Research, Development and Innovation (RDI) Fund went to firms linked to the fund’s own selection panel. The tension is between fast tracking private deep tech financing and preserving impartial public fund governance.

    What is the Research, Development and Innovation (RDI) Fund?

    1. Corpus: A Rs 1 lakh crore fund to provide low cost, long tenure financing for private research and deep technology.
    2. Anchor body: It operates under the Anusandhan National Research Foundation (ANRF) framework, with the Technology Development Board (TDB) disbursing loans.

    What is the conflict of interest concern?

    1. Panel linkage: Members of the selection panel had financial ties to firms that received public funding.
    2. Concentration: A majority of the sanctioned loans went to entities connected to those approving them.

    What safeguards does the government cite?

    1. Super majority: Approvals require a super majority of the selection committee.
    2. Stake disqualification: Members holding a stake above a threshold are barred from that decision.
    3. Cost cap: Public funding is capped at a share of total project cost.
    4. Disclosure: Members must declare any negative interest before voting.

    Why does the safeguard design still draw scrutiny?

    1. Small expert pool: India’s narrow deep tech expert base makes overlaps between funders and funded hard to avoid.
    2. Verification gap: Declared interests need independent audit to prevent capture.
  • Indian Scientists Develop a Protocol to Densify Quantum Networks

    Why in the News

    Indian scientists have developed a new routing protocol called General Concurrence Percolation (GCP) to improve the efficiency and connectivity of quantum networks, marking a significant advance in quantum communication.

    What is the General Concurrence Percolation (GCP) Protocol?

    • Innovation: A routing protocol designed to strengthen quantum entanglement across a quantum network.
    • Approach: Uses localized geometric routing to identify the shortest communication paths.
    • Key feature: Preserves intermediate network nodes instead of disconnecting them, improving network stability.
    • Outcome: Simulations show the protocol reduces the minimum entanglement required to connect an entire quantum network.

    What is Quantum Entanglement?

    • Definition: A quantum phenomenon in which two or more particles remain correlated so that the state of one is intrinsically linked to the state of the other, regardless of distance.
    • Challenge: Entanglement weakens over long distances, making reliable quantum communication difficult.
    • Importance: It is the foundation of quantum communication, quantum cryptography, and quantum computing.

    Why is the Development Significant?

    • Improves the efficiency of long distance quantum communication.
    • Reduces the amount of entanglement needed for network connectivity.
    • Makes future quantum internet infrastructure more robust and scalable.
    • Supports secure communication through quantum encryption technologies.
    • Strengthens India’s capabilities in advanced quantum technologies.

    [2026] Which of the following statements with regard to the National Quantum Mission (NQM) is/are correct?
    1. It aims at developing intermediate-scale quantum computers with 50 – 1000 physical qubits.
    2. Its implementation includes setting up of four Thematic Hubs (T-Hubs) in academic and national R&D institutes across India.
    Select the answer using the code given below :

    [A] 1 only

    [B] 2 only

    [C] Both 1 and 2

    [D] Neither 1 nor 2

  • Government Strengthens Rules Against AI Generated Deepfakes

    Why in the News

    The Government has strengthened the regulatory framework against AI generated deepfakes by amending the Information Technology (Intermediary Guidelines and Digital Media Ethics Code) Rules, 2021.

    What are the New Amendments?

    • Legal framework: Amendments have been made to the Information Technology (Intermediary Guidelines and Digital Media Ethics Code) Rules, 2021, framed under the Information Technology Act, 2000.
    • New definition: Introduces the concept of Synthetically Generated Information (SGI), covering deepfakes and other AI generated content.
    • Mandatory labelling: Platforms must clearly label synthetic content and embed traceable metadata to identify AI generated material.
    • User declaration: Significant Social Media Intermediaries (SSMIs) must obtain a declaration from users on whether uploaded content is synthetic.
    • Verification tools: SSMIs are required to deploy tools to verify user declarations.
    • Harmful content: The framework specifically targets:
      • Child Sexual Abuse Material (CSAM)
      • Non consensual intimate imagery
      • AI enabled impersonation and fraud

    What is a Deepfake?

    • Definition: Deepfakes are AI generated synthetic media in which a person’s face, voice, or likeness is created or manipulated using deep learning techniques.
    • Uses: Can be used for entertainment, education and content creation, but also for misinformation, identity theft, financial fraud and cybercrime.

    [2020] With the print state of development, Artificial Intelligence can effectively do which of the following?
    1. Bring down electricity consumption in industrial units
    2. Create meaningful short stories and songs
    3. Disease diagnosis
    4. Text -to -Speech Conversion
    5. Wireless transmission of electrical energy
    Select the correct answer using the code given below:

    [A] 1, 2, 3 and 5 only

    [B] 1, 3 and 4 only

    [C] 2, 4 and 5 only

    [D] 1, 2, 3, 4 and 5

  • All four dengue virus serotypes found co-circulating nationally, ICMR-VRDL study finds

    Why in News?

    A two year Indian Council of Medical Research-Virus Research and Diagnostic Laboratory (ICMR-VRDL) surveillance study finds all four dengue virus serotypes co-circulating nationally, raising hyperendemicity concerns and complicating future vaccine rollout.

      Key Highlights

      1. Study duration: Conducted over two years through nationwide surveillance.
      2. Conducting body: ICMR-Virus Research and Diagnostic Laboratory (VRDL) Network.
      3. Key concern: Simultaneous circulation of all serotypes indicates hyperendemicity, increasing the risk of severe dengue and complicating vaccine strategies.
        • Note: A serotype is a distinct subgroup or variation of a microorganism (such as a bacterium or virus) classified by the specific antigens found on its surface

      What is Dengue?

      1. Dengue is a viral disease caused by the dengue virus (DENV).
      2. It is transmitted by the female Aedes aegypti mosquito (also Aedes albopictus).
      3. The virus has four distinct serotypes: DENV-1, DENV-2, DENV-3 and DENV-4.
      4. Infection with one serotype provides lifelong immunity only against that serotype and temporary protection against the others.

      What is Hyperendemicity?

      1. Hyperendemicity refers to the simultaneous circulation of multiple serotypes of the same pathogen in a region.
      2. It increases the likelihood of secondary infections, which can lead to severe dengue due to Antibody-Dependent Enhancement (ADE).

      About the ICMR-VRDL Network

      • Established by the Indian Council of Medical Research (ICMR).
      • Functions as a nationwide network for diagnosis, surveillance and research on viral diseases.
      • Supports early detection and monitoring of emerging and re-emerging viral infections.

      [2017] Consider the following statements:
      1. In tropical regions, Zika virus disease is transmitted by the same mosquito that transmits dengue.
      2. Sexual transmission of Zika virus disease is possible.
      Which of the statements given above is/are correct?

      [A] 1 only

      [B] 2 only

      [C] Both 1 and 2

      [D] Neither 1 nor 2

    1. ‘Unprecedented’: OpenAI system acts on its own & hacks startup

      Why in the News?

      An OpenAI model reportedly acted autonomously and accessed Hugging Face’s systems using stolen credentials during an internal model evaluation, marking a significant development in AI safety and autonomous AI governance.

      Key Highlights

      1. The incident occurred during an internal OpenAI model evaluation to assess advanced AI capabilities and safety.
      2. The AI model reportedly used stolen credentials to gain unauthorized access to Hugging Face’s systems without direct human instruction.
      3. The episode has intensified global debates on AI safety, autonomous AI agents, and cybersecurity governance.

      Back2Basics

      AI Agent

      • An AI agent is an AI system that can perceive its environment, make decisions, and perform tasks autonomously to achieve defined goals.

      Model Evaluation & Red Teaming

      • Model Evaluation: Testing AI models for accuracy, safety, robustness, and alignment.
      • Red Teaming: Simulated adversarial testing to identify vulnerabilities before deployment.

      Key AI Terms

      • Large Language Model (LLM): A deep learning model trained on massive text datasets to understand and generate human-like language.
      • Hallucination: AI generating false or fabricated information.
      • Data Poisoning: Malicious manipulation of training data to influence model behaviour.
      • Prompt Injection: Attempts to bypass an AI system’s safeguards through crafted inputs.

      Hugging Face

      • An AI company and open-source platform hosting machine learning models, datasets, and AI tools.
      • Headquartered in New York, USA.

      Global AI Governance

      • Bletchley Declaration (2023): International cooperation on frontier AI safety.
      • Global Partnership on AI (GPAI): Promotes responsible AI; India is a founding member.

      [2026] Which of the following statements with regard to Large Language Models (LLMs) used in machine learning is/are correct?
      1. LLMs assign probabilities to the next possible words and then pick the one with the highest probability.
      2. LLMs process data through mathematical optimization to minimise prediction errors.
      3. LLMs produce unbiased outputs.
      Select the answer using the code given below :

      [A] 1 only

      [B] 1 and 2 only

      [C] 2 and 3 only

      [D] 1, 2 and 3

    2. GLP-1 Drugs and Their Effects on Skin, Hair & Nails

      Why in News?

      Growing use of GLP-1 receptor agonists for obesity and Type 2 Diabetes Mellitus (T2DM) has highlighted their effects on skin, hair, and nails.

      What is GLP-1?

      • GLP-1: Glucagon-Like Peptide-1
      • An incretin hormone that stimulates insulin secretion, reduces glucagon release, slows gastric emptying, and Suppresses appetite, aiding weight loss.
      • Common Drugs: Semaglutide, Liraglutide, Dulaglutide, and Tirzepatide (dual GIP/GLP-1 agonist).
      • Emerging Role: Early studies suggest benefits in: Psoriasis and Hidradenitis Suppurativa (HS). However, GLP-1 drugs are not yet approved as standard dermatological treatments.

      Dermatological Effects

      • Skin: Facial fat loss (“Ozempic Face”), loose skin, pigmentation, fungal infections.
      • Hair: Temporary hair shedding (Telogen Effluvium) due to rapid weight loss or nutritional deficiencies.
      • Nails: Brittle, slow-growing or peeling nails linked to nutritional deficiencies.

      Prelims Facts

      • GLP-1: Glucagon-Like Peptide-1
      • T2DM: Type 2 Diabetes Mellitus
      • GIP: Glucose-Dependent Insulinotropic Polypeptide
      • HS: Hidradenitis Suppurativa
      • PCOS: Polycystic Ovary Syndrome
      • Telogen Effluvium: Temporary hair shedding triggered by physiological stress or rapid weight loss.

      [2024] Which one of the following is synthesised in human body that dilates blood vessels and increases blood flow

      [A] Nitric oxide

      [B] Nitrous oxide

      [C] Nitrogen dioxide

      [D] Nitrogen pentoxide