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GS Paper: GS3-16.Achievements of Indians in Science & Technology

  • Lal Crater on Mars

    Why in the News?

    Back2Basics: International Astronomical Union (IAU)

    • The IAU was founded on July 28, 1919, during the Constitutive Assembly held in Brussels, Belgium.
    • Its creation was prompted by the need for international collaboration in astronomy, especially after the devastation caused by World War I.
    • It aims to promote and safeguard astronomy in all its aspects through international cooperation.
    • IAU is now headquartered in Paris, France.

    Major Activities and Initiatives

    • General Assembly: The IAU holds a general assembly every three years in varying parts of the world at which professional astronomers meet to discuss research, new cooperative ventures, and similar matters of professional interest.
    • Astronomical Nomenclature: IAU standardises the nomenclature of celestial bodies, features, and phenomena. It maintains several working groups dedicated to naming conventions for stars, planets, asteroids, and other objects.
    • Research and Collaboration: It promotes international cooperation in astronomical research and supports initiatives such as observational campaigns, data sharing, and joint projects.
    • Education and Outreach: It is actively involved in promoting astronomy education and public outreach efforts worldwide. It supports educational programs, workshops, and resources for students, teachers, and the general public.

    Membership

    1. IAU membership spans 92 countries. Out of those countries, 85 are National Members.
    2. India is represented by the Astronomical Society of India (ASI).
    3. Its members are professional astronomers from all over the world, at the D. level and beyond, who are active in professional research, education, and outreach in astronomy.

    Crater Names and Significance

    • Lal Crater: Named after Prof. Devendra Lal, former director of PRL, this 65 km wide crater is positioned at -20.98° and 209.34°.
    • Mursan Crater: Named after a town in Uttar Pradesh, India, this ~10 km wide crater is situated on the eastern side of the Lal crater’s rim.
    • Hilsa Crater: Named after a town in Bihar, India, this ~10 km wide crater is positioned on the western side of the Lal crater’s rim.

    Scientific Importance of Lal Crater

    • Lava Coverage: The entire Lal crater area, located in the Tharsis volcanic region on Mars, is covered with lava.
    • Evidence of Water: Geophysical evidence, including a 45-meter thick sedimentary deposit, suggests the presence of water in the subsurface of the Lal crater. This finding supports the theory that Mars once had water flowing on its surface.
    • Infilling Process: Mursan and Hilsa craters, positioned on either side of the Lal crater, offer insights into the infilling process of the Lal crater. Their presence indicates that infilling occurred episodically over time.

    India’s 2nd Quest for Mars

    • The ISRO is expected to launch Mangalyaan-2, or Mars Orbiter Mission 2 (MOM 2), in 2025.
    • The mission will last one year and is aimed at studying the Red Planet.
    • The successor to Mangalyaan-1, or Mars Orbiter Mission 1 (MOM 1), Mangalyaan-2 will consist of only one orbiter and will be launched atop a GSLV Mark III rocket from Satish Dhawan Space Centre.

    Other missions to Mars

    • ExoMars rover (2022): European Space Agency’s mission to explore Mars.
    • Tianwen-1 (2021): China’s Mars Mission aims to explore and study the Martian surface.
    • UAE’s Hope Mars Mission (2021): UAE’s first interplanetary mission focused on studying the Martian atmosphere.
    • NASA’s Mars Insight (2018): A lander designed to study the interior of Mars.
    • NASA’s Curiosity (2012) and Perseverance (2020): Rovers exploring the Martian surface.
    • NASA’s Mars Reconnaissance Orbiter (2005), Mars Odyssey (2001), and MAVEN (2013): Orbiters studying Mars from space.
    • Mars 2 and Mars 3 (1971): Soviet Union’s missions to Mars, which included orbiter and lander components.

     

    PYQ:

    [2016] The Mangalyaan launched by ISRO

    1. is also called the Mars Orbiter Mission.
    2. made India the second country to have a spacecraft orbit the Mars after USA
    3. made India the only country to be successful in making its spacecraft orbit Mars in its very first attempt.

    Which of the statements given above is/are correct?

    (a) 1 only
    (b) 2 and 3 only
    (c) 1 and 3 only
    (d) 1, 2 and 3

  • Portable Optical Atomic Clock for accurate timekeeping at Sea

    Why in the News?

    • Atomic clocks power GPS systems, guiding us in navigation, emergencies, and military operations.
      • Scientists are developing optical atomic clocks to enhance timekeeping accuracy for Navies.

    What are Atomic Clocks?

    • Atomic clocks are accurate timekeeping devices that use the vibrations of atoms as a precise measure of time.
    • They rely on the natural oscillations of atoms, usually Caesium or Rubidium atoms, which are extremely stable and predictable.
    • This stability allows atomic clocks to keep time with extraordinary accuracy, often losing or gaining less than a second over millions of years.
      • However they are big, need a lot of power, and are expensive, so they’re mostly used in big research places.

    Working Principle:

    • Use of Stable Atoms: Atomic clocks use stable atoms like Cs-133 to keep time really accurate.
    • Atom Energy Levels: Atoms have energy levels like steps on a ladder, and they move between these levels when they’re excited.
    • Creating Resonance: Cesium atomic clocks make caesium atoms vibrate by using microwave radiation at a certain frequency.
    • Defining Time: One second is how long it takes for caesium atoms to vibrate a certain number of times, which sets the standard for time.
    • Accuracy Control: Atomic clocks keep themselves accurate by constantly adjusting to make sure they’re vibrating at the right rate.

    Portable Optical Atomic Clocks for Maritime Use

    • New portable optical atomic clocks for ships are more accurate and durable, making them suitable for use at sea.
    • These clocks are the best at sea, which is a big deal for keeping time on ships.

    How Optical Atomic Clocks Are Different?

    • Use of Laser: Optical atomic clocks are even more accurate because they use lasers instead of microwaves.
    • Operating Frequency: They work at higher frequencies, which means they can measure smaller time intervals more precisely.
    • Narrow Linewidths: Optical atomic clocks are really stable because they have a narrow range of frequencies, which helps them stay accurate.

    Testing and Applications of Portable Optical Atomic Clocks

    • Initial Testing: Scientists tested the new clocks and found they were really stable and accurate, which is a big deal for keeping time.
    • Comparative Performance: These new clocks worked better than old ones, showing they could change how we keep time.
    • Sea Trials: Tests at sea showed the clocks worked well even on a moving ship, proving they could be used for navigation and other important tasks.

    Do you know?

    • Three rubidium atomic clocks and six hydrogen maser clocks onboard the Indian Regional Navigation Satellite System (IRNSS) had failed.
    • The failed satellite, IRNSS-1A, is still being used for messaging activities, and the data from other operational satellites will be used to maintain the system’s functionality.

     

    PYQ:

    [2018] Why is Indian Regional Navigational Satellite System (IRNSS) needed? How does it help in navigation?

    [2018] With reference to the Indian Regional Navigation Satellite System (IRNSS), consider the following statements:

    1. IRNSS has three satellites in geostationary and four satellites in geosynchronous orbits.
    2. IRNSS covers entire India and about 5500 sq. km beyond its borders.
    3. India will have its own satellite navigation system with full global coverage by the middle of 2019.

    Which of the statements given above is/are correct?

    (a) 1 only
    (b) 1 and 2 only
    (c) 2 and 3 only
    (d) None

  • What are Coronal Mass Ejections (CMEs)?

    Why in the News?

    • India’s solar mission Aditya-L1 recently captured images of the Sun and it’s Coronal Mass Ejections (CMEs) during a solar storm in May.
      • The Active region AR13664 on the Sun erupted several X-class and M-class flares, which were associated with Coronal Mass Ejections (CMEs).

    Coronal Mass Ejections (CMEs)

    • CMEs were discovered in 1971 and established their importance in solar-terrestrial relations later in the 1980s.
    • It consists of massive clouds of solar plasma and magnetic field lines.
    • It typically accompanies solar flares and filament eruptions.
    • The frequency of CMEs varies with the 11-year solar cycle, with about one a week observed during solar minimum and an average of two to three CMEs per day observed near solar maximum
    • They travel at thousands of km per hour.
    • They can lead to geomagnetic storms, aurorae, and in extreme cases, damage to electrical power grids.
    • Not all CMEs interact with Earth, but those that do can cause disruptions to satellite communications and power grids.
    • Halo CMEs are Earth-directed CMEs visible as rings in white-light coronagraph observations.

    About Aditya-L1:

    • Aditya-L1 mission is India’s first space mission to observe the Sun.
    • It is ISRO’s 2nd space-based astronomy mission after AstroSat, which was launched in 2015.
    • It was launched on September 2nd 2023 to observe the Sun and the solar corona.
    • The L1 point is a location in space where the gravitational forces of two massive objects, such as the Earth and the Sun, balance each other out, allowing a spacecraft to “hover” in a stable orbit.

    Launch Details: 

    • Polar Satellite Launch Vehicle (PSLV) with 7 payloads (instruments) on board.

    The 7 payloads include: 

      1. Visible Emission Line Coronagraph (VELC): Images of the solar corona in visible light to study its structure and dynamics.
      2. Solar Ultraviolet Imaging Telescope (SUIT): Images the solar chromosphere and transition region in ultraviolet light to understand heating and dynamics.
      3. Solar Low Energy X-ray Spectrometer (SoLEXS): Measures solar X-ray spectrum to study solar flares and coronal mass ejections.
      4. High Energy L1 Orbiting X-ray Spectrometer (HEL1OS): Measures high-energy solar X-rays to understand particle acceleration.
      5. Plasma Analyser Package for Aditya (PAPA): Measures solar wind plasma properties to study its interaction with Earth’s magnetosphere.
      6. Aditya Solar Wind Particle Experiment (ASPEX): Measures energetic particle properties in the solar wind to study their effects on Earth’s atmosphere.
    • Solar Irradiance Monitor (SIM): Measures solar irradiance variations and their impact on Earth’s climate.

    Objectives:

    • Aditya L1 will study the coronal heating, solar wind acceleration, coronal magnetometry, origin and monitoring of near-UV solar radiation and continuously observe the photosphere, chromosphere and corona, solar energetic particles and the magnetic field of the Sun.

    Location:

    • Aditya is placed in L1 Halo orbit which is about 1.5 million km from the Earth. The orbit allows the mission to look at the Sun continuously.
    • L1 refers to Lagrangian/Lagrange Point 1, one of 5 points in the orbital plane of the Earth-Sun system.
    • Lagrange Points are positions in space where the gravitational forces of a two-body system like the Sun and Earth produce enhanced regions of attraction and repulsion.

    PYQ:

    [2017] The terms ‘Event Horizon’, ‘Singularity’, ‘String Theory’ and ‘Standard Model’ are sometimes seen in the news in the context of-

    (a) Observation and understanding of the Universe

    (b) Study of the solar and lunar eclipses

    (c) Placing satellites in the orbit of the Earth

    (d) Origin and evolution of living organisms on the Earth

     

    https://www.thehindu.com/sci-tech/science/isro-releases-images-of-sun-captured-by-aditya-l1-during-may-solar-storm/article68273124.ece

  • PraVaHa tool for Aerodynamic Design and Analysis

    Why in the News?

    The Indian Space Research Organisation (ISRO) has launched the Computational Fluid Dynamics (CFD) software named Parallel RANS Solver for Aerospace Vehicle Aero-thermo-dynamic Analysis (PraVaHa).

    About PraVaHa

    • PraVaHa was developed at ISRO’s Vikram Sarabhai Space Centre (VSSC), showcasing India’s prowess in aerospace technology.
    • It can simulate both external and internal flows on various aerospace vehicles, including launch vehicles, and winged, and non-winged re-entry vehicles.
    • It facilitates initial aerodynamic design studies by evaluating numerous configurations, crucial for optimizing vehicle performance and safety.

    Role of Computational Fluid Dynamics (CFD)

    • CFD predicts aerodynamic and aerothermal loads by solving governing equations. It has matured to offer high accuracy and fast simulations, addressing aerospace challenges like high pressure and intense heat flux.

    Integration in Gaganyaan Program

    • Key Applications: PraVaHa plays a pivotal role in the Gaganyaan program, facilitating aerodynamic analysis of human-rated launch vehicles such as HLVM3, Crew Escape System (CES), and Crew Module (CM).
    • Scalability and Collaboration: Designed to leverage both CPU and GPU architectures, PraVaHa ensures compatibility with existing and future supercomputing facilities, fostering collaboration with academic and government institutions.

    PYQ:

    [2010] In the context of space technology, what is “Bhuvan”, recently in the news?

    (a) A mini satellite launched by ISRO for promoting the distance education in India.

    (b) The name given to the next Moon Impact Probe, for Chandrayaan-II.

    (c) A geoportal of ISRO with 3D imaging capabilities of India.

    (d) A space telescope developed by India.

  • Agnibaan Sub Orbital Technology Demonstrator (SOrTeD)

    Why in the News?

    Agnikul Cosmos Private Limited, a space start-up from Chennai, made history by launching the world’s first rocket with a single-piece 3D-printed engine, named Agnibaan Sub Orbital Technology Demonstrator (SOrTeD), from Sriharikota.

    About 3D Printed PS4 Engine

    • The PS4 engine, which forms the uppermost stage of the Polar Satellite Launch Vehicle (PSLV), comprises two Earth-storable liquid engines.
    • It uses a bipropellant combination of nitrogen tetroxide as the oxidizer and monomethyl hydrazine as the fuel, both developed by ISRO’s Liquid Propulsion Systems Centre.
    • This same engine is employed in the Reaction Control System (RCS) of the first stage (PS1) of PSLV.
    • ISRO redesigned the PS4 engine for production using 3D printing technology.
    • The technology helped ISRO bring down the number of parts in the engine from 14 to a single piece.
    • ISRO was able to eliminate 19 weld joints and saved 97% of raw material.
    • It also reduced the overall production time by 60%.

    What is Agnibaan SOrTeD (Suborbital Tech Demonstrator)?

    • Agnibaan SOrTeD is a single-stage launch vehicle powered by Agnikul’s patented Agnilet semi-cryogenic engine.
    • In contrast to traditional sounding rockets, Agnibaan SOrTeD’s vertical take-off and precise trajectory enable orchestrated manoeuvres during flight.

    PYQ:

    [2018] With reference to India’s satellite launch vehicles, consider the following statements:

    1. PSLVs launch the satellites useful for Earth resources monitoring whereas GSLVs are designed mainly to launch communication satellites.
    2. Satellites launched by PSLV appear to remain permanently fixed in the same position in the sky, as viewed from a particular location on Earth.
    3. GSLV Mk III is a four-staged launch vehicle with the first and third stages using solid rocket motors; and the second and fourth stages using liquid rocket engines.

    Which of the statements given above is/are correct?

    (a) 1 only
    (b) 2 and 3
    (c) 1 and 2
    (d) 3 only

  • NISAR Satellite will be able to monitor Tectonic Movements: ISRO chief

    Why in the News?

    The ISRO Chief has confirmed that the NISAR Satellite would be able to monitor the Tectonic Movements of Earth with high precision with a centimeter accuracy.

    • Originally planned for July, the NISAR launch may be delayed to October-November due to issues on the U.S. spacecraft side.

    About NISAR Satellite:

    • NISAR (NASA-ISRO Synthetic Aperture Radar) is a joint satellite mission between NASA and ISRO.
    • It would be a Low Earth Orbit observatory.
    • This mission is aimed at enhancing our understanding of Earth’s natural processes and environmental changes.

    Features of NISAR Satellite:

    • L-band and S-band Radar Frequencies:
        • NASA is responsible for the L-band radar, while ISRO provides the S-band radar.
        • This dual-band capability allows the satellite to monitor and measure Earth’s surface with high precision in all weather conditions and throughout both day and night.
    • Large Deployable Antenna: 
        • It is equipped with a large deployable antenna that measures 12 meters in diameter.
        • This large antenna enhances the satellite’s ability to capture detailed radar images with high resolution.
        • It will have a 39-foot stationary antenna reflector, made of a gold-plated wire mesh to focus radar signals emitted and received by the upward-facing feed on the instrument structure.
    • Rapid Coverage: 
        • NISAR is designed to scan the entire Earth every 12 days.
        • This rapid revisiting is crucial for observing and understanding temporal changes in the environment, such as shifting vegetation patterns, ice dynamics, and other critical parameters.
    • Versatile Monitoring Capabilities: 
      • It will monitor Earth’s ecosystems and dynamics, including forest biomass, ice sheet collapses, and natural hazards such as earthquakes, tsunamis, and volcanic eruptions.
      • Its radar system can penetrate vegetation and soil to provide three-dimensional reconstructions of structures and changes.

    PYQ:

    [2015] The term ‘IndARC’ sometimes seen in the news, is the name of?

    (a) An indigenously developed radar system inducted into Indian Defence.

    (b) India’s satellite to provide services to the countries of Indian Ocean Rim.

    (c) A scientific establishment set up by India in Antarctic region.

    (d) India’s underwater observatory to scientifically study the Arctic region.

  • What is 3D Printing and How does it Work?

    Why in the news?

    • The Indian Space Research Organisation (ISRO) successfully tested a liquid rocket engine made with the help of additive manufacturing technology — commonly known as 3D printing.

    3D Printed PS4 Engine

    • The technology helped ISRO bring down the number of parts in the engine from 14 to a single piece.
    • ISRO was able to eliminate 19 weld joints and saved 97% of raw material.
    • It also reduced the overall production time by 60%.

    What is 3D printing?

    • 3D printing is a process that uses computer-created design to make three-dimensional objects layer by layer.
    • It is an additive process, in which layers of a material like plastic, composites or bio-materials are built up to construct objects that range in shape, size, rigidity, and colour.
    • Common 3D Printing materials include Acrylonitrile Butadiene Styrene (ABS), Carbon Fiber Filaments, Conductive Filaments, Metal Filaments etc.

    How is 3D printing done?

    • To carry out 3D printing, one needs a personal computer connected to a 3D printer.
    • All they need to do is design a 3D model of the required object on computer-aid design (CAD) software and press ‘print’.
    • The 3D printer does the rest of the job.
    • 3D printers construct the desired object by using a layering method, which is the complete opposite of the subtractive manufacturing processes.

    Benefits offered:

    3D printing offers several key advantages over traditional manufacturing, including:

    • Complexity without Extra Cost: Allows for intricate designs without increasing production costs.
    • Rapid Prototyping: Speeds up the development process by quickly producing prototypes from digital designs.
    • Customization: Ideal for producing customized or bespoke items in small quantities.
    • Reduced Waste: Generates minimal waste compared to traditional subtractive methods, making it more sustainable.
    • Cost-Effective for Low Volumes: Avoids the need for expensive tooling and molds, beneficial for small production runs.

    PYQ:

    [2018] “3D printing” has applications in which of the following?

    1. Preparation of confectionery items
    2. Manufacture of bionic ears
    3. Automotive industry
    4. Reconstructive surgeries
    5. Data processing technologies

    Select the correct answer using the code given below:

    (a) 1, 3 and 4 only

    (b) 2, 3 and 5 only

    (c) 1 and 4 only

    (d) 1, 2, 3, 4 and 5

  • Studies Suggest More Water Ice on Moon: ISRO 

    Why in the news?

    A study has revealed evidence for enhanced possibility of sub-surface water ice occurrence in the polar craters of the Moon, according to ISRO.

    Water Ice on Moon: ISRO’s Findings 

    • The research indicates that the amount of sub-surface ice within the first few meters is significantly greater, about 5-8x more, than that found on the lunar surface.
    • Moreover, the study reveals that the Northern Polar region harbors twice as much water ice as the southern polar region.
    • It highlights the necessity of drilling to access this ice for future missions and sustained human presence on the Moon.

    Origin of Water Ice:

    • The study validates the hypothesis that sub-surface water ice in lunar poles originated from out-gassing during volcanic activity in the Imbrian period.
    • It suggests that Lunar Mare Volcanism and preferential impact cratering govern the distribution of water ice on the Moon.

    Methodology:

    • The research team utilized seven instruments aboard the NASA robotic spacecraft Lunar Reconnaissance Orbiter (LRO), including radar, laser, optical, neutron spectrometer, ultra-violet spectrometer, and thermal radiometer. LRO hovers over Lunar South Pole.
    • These instruments provided crucial data to understand the origin and distribution of water ice on the lunar surface.

    Significance of the findings

    • Accurate knowledge of water ice distribution and depth is vital for identifying suitable landing and sampling sites for future lunar missions.
    • The study supports ISRO’s future plans for in-situ volatile exploration on the Moon, aligning with its broader lunar exploration objectives.

    PYQ:

    Q. Discuss India’s achievements in the field of Space Science and Technology. How the application of this technology helped India in its socio-economic development? (2016)

  • [pib] SPACE Testing & Evaluation hub for Sonar Systems

    Why in the news?

    A state-of-the-art SPACE testing and evaluation hub for sonar systems, designed for the Indian Navy, was inaugurated by DRDO.

    About Submersible Platform for Acoustic Characterisation and Evaluation (SPACE)

    • The SPACE is located at the Underwater Acoustic Research Facility in Kulamavu, Idukki, Kerala.
    • It is developed by the Naval Physical & Oceanographic Laboratory of DRDO.
    • It is set to become a premier testing and evaluation hub for sonar systems deployed on various Indian Navy platforms, including ships, submarines, and helicopters.

    Key Features of SPACE:

    • SPACE comprises two distinct components:
    1. Floating Platform on the water surface and
    2. Submersible platform capable of descending to depths of up to 100 meters using winch systems.
    • After completing operations, the submersible platform can be winched up and docked with the floating platform, ensuring efficient utilization of resources.

    Functions and Capabilities:

    • The primary function of SPACE is the evaluation of complete sonar systems, facilitating rapid deployment and retrieval of scientific packages such as sensors and transducers.
    • It will serve for surveying, sampling, and data collection of air, surface, mid-water, and reservoir floor parameters utilizing modern scientific instrumentation.
    • It will address the data processing and sample analysis requirements, ushering in a new era of Anti-Submarine Warfare research capabilities.

    What is SONAR?

    • SONAR stands for “Sound Navigation and Ranging.”
    • It’s a technique used for detecting and locating objects underwater by transmitting sound waves and analyzing the echoes they produce.

    Here’s how it works:

    1. Sound Transmission: A SONAR system sends out pulses of sound waves, typically at frequencies beyond the range of human hearing. These sound waves travel through the water and propagate in all directions.
    2. Object Detection: When the sound waves encounter an object underwater, such as a submarine, seafloor, or marine life, they reflect off the object and return to the SONAR system as echoes.
    3. Echo Reception: The SONAR system receives the echoes of the transmitted sound waves and measures the time it takes for them to return. By knowing the speed of sound in water and the time it takes for the echoes to return, the system can calculate the distance to the object.
    4. Data Analysis: The received echoes are processed and analyzed to create a visual representation of the underwater environment. This information helps operators identify and locate objects of interest, navigate safely, and map the seafloor.

     

    PYQ:

    [2020] “The experiment will employ a trio of spacecraft flying in formation in the shape of an equilateral triangle that has sides one million kilometres long, with lasers shining between the craft,” The experiment in question refers to-

    (a) Voyager-2

    (b) New Horizons

    (c) LISA Pathfinder

    (d) Evolved LISA

  • Crafted in Indian labs, NexCAR19 takes India to next level in Cancer Care

    Why in the News? 

    • President Droupadi Murmu launched India’s first indigenously-developed CAR T-cell therapy, hailing it as a major breakthrough against cancer.
    • This therapy was developed by the Indian Institute of Technology (IIT) Bombay and the Tata Memorial Centre, and it is known as ‘NexCAR19 CAR T-cell therapy’.

    BACK2BASICS:

    What is CAR T cell thearpy? 

    CAR T-cell therapy is a type of immunotherapy that involves modifying a patient’s T cells, a type of white blood cell that plays a crucial role in the immune system, to recognize and attack cancer cells. This therapy is designed to target specific proteins found on the surface of cancer cells, such as CD19, which is commonly found on B cells.

    How are CAR-T cells made?

    Significance of CAR T Thearpy:

    • Promising results:  This therapy has shown promising results in treating some types of blood cancers, including certain kinds of lymphoma, pediatric leukemia, and adult leukemia.  It has shown with approximately 70% of patients responding to the treatment.
    • Less time for treatment: CAR T-cell therapies are generally a single infusion with less than 2 weeks of inpatient care, while stem cell transplants and chemotherapy treatment regimens can take months to complete

    Limitiations of CAR-T Therapy:

    • Risks of CAR-T Therapy: The efficacy of CAR-T therapy varies from person to person, and it is too early to declare it a complete cure. While it has shown remarkable progress in challenging cases, its effectiveness is not universal.
    • High Cost Therapy: NexCAR19 is priced at a fraction of its US counterpart, it remains relatively high for many Indians, ranging from ₹40 to 45 lakh.
    • It’s Side Effects includes:
      • Cytokine Release Syndrome (CRS): CRS is the most common side effect of CAR-T therapy, triggering an ‘Inflammatory Response’ that leads to immune system hyperactivity.
      • Neurotoxicity: Although not observed in early-stage clinical trials, neurotoxicity is a common side effect of CAR-T therapy that can manifest as confusion, seizures, or difficulty speaking or walking.
      • Infections and Blood Cell Counts: Patients undergoing CAR-T therapy may experience infections and low blood cell counts as anticipated side effects.

    Conclusion: India’s is moving towards heralding a breakthrough in Cancer Care Therapy. Despite cost challenges, Government efforts are aimed to enhance accessibility and better outputs in Healthcare Sector.