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GS Paper: GS3-17.Awareness in the fields of IT, Space, Computers, Robotics, Nano-technology, Bio-technology and issues relating to Intellectual Property Rights.

  • Reimei: World’s 1st Hybrid Quantum Supercomputer goes Online

    Why in the News?

    Japan has officially launched the world’s first hybrid quantum supercomputer, integrating a 20-qubit quantum processor, Reimei, into Fugaku, the world’s sixth-fastest supercomputer.

    About Reimei

    • Reimei is a 20-qubit trapped-ion quantum computer developed by Quantinuum and integrated into Fugaku, the world’s sixth-fastest supercomputer, at Riken, Japan.
    • It is the first fully operational hybrid quantum supercomputer, combining quantum and classical computing for advanced problem-solving.
    • Key Features:
      • Trapped-Ion Qubits: Unlike superconducting qubits, Reimei uses trapped-ion technology, offering higher stability, longer coherence times, and stronger qubit connectivity.
      • Hybrid Integration: Works alongside Fugaku to solve complex calculations faster than classical supercomputers.
      • Ion Shuttling: Enables physical movement of qubits, allowing for more complex quantum algorithms.
      • Error Correction: Uses logical qubits, reducing error rates 800 times lower than standard qubits.
    • Applications:
      • Physics & Chemistry Research: Used for molecular simulations, material science, and high-energy physics.
      • Quantum Cryptography & AI: Enhances cybersecurity and artificial intelligence models.
      • Optimization & Machine Learning:  Solves large-scale optimization problems.
    • Significance:
      • Bridges classical and quantum computing, serving as a transition to fully scalable quantum systems.
      • Paves the way for real-world quantum applications, accelerating scientific and technological advancements.

    PYQ:

    [2022] Which one of the following is the context in which the term “qubit” is mentioned?

    (a) Cloud Services
    (b) Quantum Computing
    (c) Visible Light Communication Technologies
    (d) Wireless Communication Technologies

     

  • [pib] Nationwide Mass Drug Administration (MDA) Campaign for Lymphatic Filariasis (LF) Elimination 

    Why in the News?

    Union Minister for Health and Family Welfare has launched the Annual Nationwide Mass Drug Administration (MDA) Campaign to eliminate Lymphatic Filariasis (LF).

    About Lymphatic Filariasis (LF):

    • Lymphatic Filariasis (LF), or “Hathi Paon”, is a mosquito-borne parasitic disease caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori.
    • It affects the lymphatic system, leading to swelling of limbs (lymphoedema) and scrotal swelling (hydrocele), causing permanent disability.
    • LF spreads through repeated mosquito bites, making it a major public health challenge in tropical regions, including India.
    • India aims to eliminate LF by 2027, ahead of the 2030 Sustainable Development Goal (SDG) target.

    What is Mass Drug Administration (MDA)?

    • MDA is a large-scale public health campaign where anti-filarial medicines are administered to all eligible individuals in endemic areas to stop LF transmission.
    • Medication Regimens:
      • Double Drug Therapy (DA): Diethylcarbamazine Citrate (DEC) + Albendazole
      • Triple Drug Therapy (IDA): Ivermectin + DEC + Albendazole
    • Key Features of MDA
      • Door-to-door supervised drug administration ensures high coverage.
      • Drugs are safe, free, and given twice a year in targeted districts.
      • MDA is crucial for eliminating LF, as it reduces parasite transmission and protects millions from disability.
    • EXCEPTIONS: Children below 2 years, pregnant women, and seriously ill individuals.

    PYQ:

    [2017] Consider the following statements:

    1. In tropical regions, Zika virus disease is transmitted by the same mosquito that transmits dengue.

    2. Sexual transmission of Zika virus disease is possible.

    Which of the statements given above is/are correct?

    (a) 1 only

    (b) 2 only

    (c) Both 1 and 2

    (d) Neither 1 nor 2

     

  • Genotype D1.1

    Why in the News?

    The US Department of Agriculture has confirmed a new spillover of H5N1 avian flu genotype D1.1 into dairy cattle in the United States.

    What is Genotype D1.1?

    • Genotype D1.1 is a strain of the H5N1 highly pathogenic avian influenza (HPAI) virus, primarily found in poultry and wild birds.
    • It is part of the H5 clade 2.3.4.4b, which has been responsible for multiple outbreaks worldwide.
    • It was recently confirmed in dairy herds in Churchill County, Nevada, USA.
    • Symptoms in Cattle: Includes fever, reduced milk production, coughing, sneezing, and nasal discharge.
    • Differences from B3.13: Genotype B3.13, the previous dominant H5N1 strain in cattle, caused milder infections in humans, whereas D1.1 has led to more severe cases.

    Bird Flu (Avian Influenza) Spillover of H5N1 Virus

    • A spillover event occurs when a virus jumps from its natural host species (wild birds) to other animals or humans.
    • It spreads through wild bird migration routes, carrying the virus across continents.
    • The virus has been detected in unpasteurized milk from infected cows, raising concerns about worker exposure.

    Impacts on India

    • Although genotype D1.1 has not been detected in India, the growing spread of H5N1 in cattle and humans abroad raises concerns for public health and livestock industries in India.
    • India is part of major bird migration routes (Central Asian Flyway & East Asian-Australasian Flyway), making it vulnerable to H5N1 spread from infected wild birds.
    • With India being the world’s largest milk producer, a spillover of H5N1 into dairy cattle could severely impact milk production and exports.
    • While human cases remain rare, a mutation allowing human-to-human transmission could lead to a pandemic-like scenario.
    •  India poultry products exports to Middle Eastern and Asian markets; an H5N1 outbreak could lead to bans and economic losses.

    PYQ:

    [2015] H1N1 virus is sometimes mentioned in the news with reference to which one of the following diseases?

    (a) AIDS

    (b) Bird flu

    (c) Dengue

    (d) Swine flu

     

  • What is Brucellosis?

    Why in the News?

    An 8-year-old girl in Kerala, recently succumbed to brucellosis, a bacterial infection primarily caused by the consumption of unpasteurised milk.

    About Brucellosis

    • Brucellosis is a bacterial infection caused by Brucella species, primarily affecting cattle, goats, sheep, swine, and dogs.
    • Humans contract it through direct contact with infected animals, consuming contaminated animal products, or inhaling airborne agents.
    • According to the World Health Organization (WHO), the most common cause is the ingestion of unpasteurised milk or cheese from infected livestock.
    • Symptoms and Risk Factors:
      • Symptoms: Fever, weakness, weight loss, and general discomfort. The incubation period is 1-2 months, but most cases develop within 2-4 weeks.
      • At-Risk Groups: Farmers, butchers, veterinarians, hunters, and laboratory personnel handling infected animal tissues.
    • Treatment and Prevention:
      • Treatment: Doxycycline (100 mg, twice daily for 45 days) and Streptomycin (1 g daily for 15 days) as per medical advice.
      • Prevention: Vaccination of livestock, pasteurisation of milk, and public awareness campaigns to discourage the consumption of unpasteurised dairy products.

  • Second National Gene Bank

    Why in the News?

    As part of the Union Budget 2025-26, Finance Minister announced the establishment of a second National Gene Bank in India.

    About the First National Gene Bank

    • Established in 1996 by the Indian Council of Agricultural Research-National Bureau of Plant Genetic Resources (ICAR-NBPGR) in New Delhi.
    • Functions as India’s primary facility for preserving plant genetic resources (PGRs) to safeguard biodiversity.
    • Operates through 12 regional stations across the country for collection and storage of vital crop germplasms.
    • Preserves 0.47 million accessions (plant material for breeding and research) as of January 15, 2025.
    • Maintains genetic resources using four conservation methods:
      • Seed Genebank (-18°C) – Stores seeds for long-term conservation.
      • Cryogenebank (-170°C to -196°C) – Preserves plant tissues in liquid nitrogen.
      • In-vitro Genebank (25°C) – Maintains plant cultures in controlled environments.
      • Field Genebank – Conserves live plants for breeding and research.
    • Protects diverse crop groups, including cereals, millets, legumes, oilseeds, and vegetables.

    About the Second National Gene Bank

    • It aims to store over 10 lakh germplasm lines to strengthen food and nutritional security.
    • It will complement the first National Gene Bank and expand genetic conservation capacity.
    • It is designed to support both public and private sectors in conserving genetic diversity.
    • Features and Significance:  
      • Largest conservation facility in India, expanding germplasm storage capacity beyond the existing 0.47 million accessions in the first gene bank.
      • Ensures germplasm accessibility for future generations, preventing genetic erosion due to habitat loss or overexploitation.
      • Protects India’s agricultural heritage by preserving native, traditional, and rare plant varieties.
      • Aligns with global conservation efforts, including India’s Seed Vault in Chang La (Ladakh) and the Svalbard Global Seed Vault (Norway).
      • Promotes ex-situ conservation, ensuring crop diversity for future breeding, research, and sustainable farming.

    PYQ:

    [2021] What are the research and developmental achievements in applied biotechnology? How will these achievements help to uplift the poorer sections of society?

  • Asteroid Bennu Samples hold Secrets of Life’s Origins

    Why in the News?

    NASA’s OSIRIS-REx (Origins, Spectral Interpretation, Resource Identification, Security–Regolith Explorer) mission has delivered samples from asteroid Bennu, revealing amino acids, nucleobases, and signs of ancient saltwater, key components in the origins of life.

    Key Findings of the Study:

    • 14 out of 20 amino acids essential for proteins on Earth were found.
    • All five nucleo-bases used in DNA and RNA were detected, indicating prebiotic chemistry beyond Earth.
    • Ammonia & Formaldehyde compounds can react under suitable conditions to form complex organic molecules.
    • It thus supports the idea that asteroids delivered key building blocks for life to early Earth.
    • Calcite, halite, sylvite, and trona were found, indicating prolonged exposure to liquid water.
    • Similar briny conditions have been observed on Ceres and Enceladus, suggesting the solar system had widespread environments suitable for organic chemistry.
    • Life on Earth exclusively uses left-handed amino acids, but Bennu samples show an equal mix, raising questions about why life evolved with this preference.

    About Asteroid Bennu  

    • Asteroid Bennu is a carbon-rich asteroid that orbits between Earth and Mars.
    • It is believed to be a primitive remnant of the early solar system, holding clues to the origins of life.
    • The asteroid is porous, with up to 60% empty space, affecting its collision potential with Earth in the distant future.
    • It periodically ejects material, classifying it as an active asteroid.
    • OSIRIS-REx was NASA’s first asteroid sample-return mission, launched in 2016 to study and collect material from Bennu’s surface.
      • The spacecraft arrived at Bennu in 2018, mapped its surface for two years, and collected samples in 2020.
      • It successfully returned the material to Earth in 2023.
    • The mission aimed to analyze Bennu’s composition, understand its water history, and study the organic molecules that may have played a role in the origin of life.

    Significance of the Study:

    • It strengthens the theory that asteroids contributed to life’s origins by delivering organic molecules and water to early Earth.
    • It confirms that essential ingredients for life were widespread in the early solar system, increasing the possibility of life beyond Earth.
    • It helps refine planetary defense strategies, as Bennu has a small chance of impacting Earth in the future.

    PYQ:

    [2011] What is the difference between asteroids and comets?

    1. Asteroids are small rocky planetoids, while comets are formed of frozen gases held together by rocky and metallic material.
    2. Asteroids are found mostly between the orbits of Jupiter and Mars, while comets are found mostly between Venus and Mercury.
    3. Comets show a perceptible glowing tail, while asteroids do not.

    Which of the statements given above is/are correct?

    (a) 1 and 2 only
    (b) 1 and 3 only
    (c) 3 only
    (d) 1, 2 and 3

  • Labrys portucalensis F11

    Why in the News?

    A research team has discovered that Labrys portucalensis F11, a strain of aerobic bacteria from the Xanthobacteraceae family, can break down and transform multiple types of per- and polyfluoroalkyl substances (PFAS), a group of persistent environmental pollutants.

    About Labrys portucalensis F11

    • It is a type of bacteria that can break down harmful chemicals known as PFAS (Per- and Polyfluoroalkyl Substances).
    • It was first found in contaminated soil at an industrial site in Portugal.
    • Scientists have discovered that it can remove fluorine from certain chemical pollutants, making them less toxic.
    • PFAS are known as “forever chemicals” because they do not break down easily in nature.
    • Labrys portucalensis F11 can digest PFAS, helping to clean up polluted soil and water.

    How does it work?

    • It attacks the strong chemical bonds in PFAS, removing fluorine atoms.
    • It uses carbon from PFAS as food, helping it grow while reducing pollution.
    • It survives in oxygen-rich environments, making it ideal for cleaning up industrial waste sites.
    • In 100 days, it broke down 90% of PFOS, one of the most harmful PFAS chemicals.
    • Unlike most bacteria, it can also break down PFAS leftovers, making them even safer.

    Back2Basics: Per- and Polyfluoroalkyl Substances (PFAS)

    • Per- and Polyfluoroalkyl Substances (PFAS) are a group of synthetic chemicals widely used in industrial and consumer products for their waterproof, grease-resistant, and non-stick properties.
    • PFAS are commonly found in non-stick cookware (Teflon), waterproof clothing, food packaging, fire-fighting foams, and industrial applications.
    • These chemicals are known for their high resistance to heat, water, and oil, making them useful but also environmentally persistent.
    • Common Uses:
      • Non-stick cookware (Teflon), waterproof fabrics, stain-resistant coatings, and fire-fighting foams.
      • Industrial applications such as metal plating, food packaging, and electronics manufacturing.
    • Environmental and Health Concerns:
      • PFAS are often called “forever chemicals” because they do not naturally degrade and persist in soil, water, and living organisms.
      • Exposure to PFAS has been linked to cancer, liver damage, immune system disruption, and hormonal imbalances.
    • Regulatory Actions:
      • In 2023, the U.S. Environmental Protection Agency (EPA) designated PFOS (a type of PFAS) as a hazardous substance, requiring strict monitoring and clean-up efforts.
      • Governments worldwide are phasing out PFAS use and funding research into bioremediation technologies like the F11 bacteria-based clean-up approach.
      • In 2020, the Bureau of Indian Standards (BIS) adopted international criteria for sampling and testing certain PFAS compounds, such as perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS).
        • However, comprehensive policies to regulate or ban PFAS are still lacking.

     

    PYQ:

    [2013] Which of the following can be found as pollutants in the drinking water in some parts of India?

    1. Arsenic
    2. Sorbitol
    3. Fluoride
    4. Formaldehyde
    5. Uranium

    Select the correct answer using the codes given below:

    (a) 1 and 3 only
    (b) 2, 4 and 5 only
    (c) 1, 3 and 5 only
    (d) 1, 2, 3, 4 and 5

  • What is Guillain-Barre Syndrome (GBS)?

    Why in the News?

    In an alarming move, the Guillain-Barre Syndrome (GBS) cases rise to 110 in Pune.

    What is Guillain-Barré Syndrome (GBS)?

    • GBS is an autoimmune disorder where the immune system attacks peripheral nerves, causing muscle weakness and, in severe cases, paralysis.
    • It is rare, affecting 1–2 per 100,000 people annually.
    • It is more common in adults and males.
    • It is often triggered by viral or bacterial infections, especially Campylobacter jejuni (a cause of gastroenteritis), influenza, Epstein-Barr virus, Zika virus, or, in rare cases, vaccinations.
    • Its Symptoms: 
      • Early signs: Tingling, weakness in legs spreading to the upper body, pins-and-needles sensation, back pain.
      • Severe cases: Paralysis, breathing difficulties, loss of speech, vision problems.
      • Complications: Can affect the autonomic nervous system, leading to irregular heartbeat, blood pressure fluctuations, and potential respiratory failure.

    Treatment and Recovery:

    • No definitive cure, but treatments include:
      • Plasma Exchange (Plasmapheresis): Removes harmful antibodies attacking nerves.
      • Intravenous Immunoglobulin (IVIG) Therapy: Injects healthy antibodies to counteract immune attacks.
    • Supportive care: Some patients require ventilator support, physical therapy, and months to years of rehabilitation.

    PYQ:

    [2022] In the context of vaccines manufactured to prevent COVID-19 pandemic, consider the following statements:

    1. The Serum Institute of India produced COVID-19 vaccine named Covishield using mRNA platform.
    2. Sputnik V vaccine is manufactured using vector-based platform.
    3. COVAXIN is an inactivated pathogen-based vaccine.

    Which of the statements given above are correct?

    (a) 1 and 2 only
    (b) 2 and 3 only
    (c) 1 and 3 only
    (d) 1, 2 and 3

  • What is Stargardt Disease?

    Why in the News?

    Researchers have created a gene-editing tool to fix ABCA4 gene mutations, offering hope for treating Stargardt disease, a rare condition that causes progressive vision loss.

    What is Stargardt Disease?

    • Stargardt Disease is a rare inherited eye disorder that causes progressive vision loss, primarily affecting the central part of the retina, called the macula.
    • It is typically caused by mutations in the ABCA4 gene, which disrupts the body’s ability to use Vitamin A, leading to an excessive buildup of lipofuscin (yellowish-brown pigment) in retinal cells.
    • The disease commonly begins in childhood or early adulthood and is usually bilateral, involving both eyes.
    • Currently, there is no cure for Stargardt Disease.

    Symptoms of Stargardt Disease

    • Progressive vision loss, particularly affecting central vision.
    • Difficulty seeing in low light (night blindness).
    • Blurred or distorted vision, with colors appearing less vivid.
    • Appearance of dark spots or areas of vision loss in the central visual field.
    • Gradual deterioration of visual acuity, leading to potential legal blindness.

    Present Scenario in India

    • According to a 2023 study by L.V. Prasad Eye Institute, Hyderabad:
      • The disease predominantly affects males and typically manifests during the second decade of life.
      • Estimated prevalence: 1 in 8,000 to 10,000 individuals.
      • 10.79% of patients had a family history of Stargardt disease, while 10.69% were from consanguineous marriages.
    • In India, Stargardt disease is a not uncommon hereditary condition, with limited treatment options available.

  • What is Dark Oxygen?

    Why in the News?

    Deep-sea researchers have initiated a groundbreaking project to explore dark oxygen, a form of oxygen produced in complete darkness on the ocean floor.

    What is Dark Oxygen?

    • Dark oxygen refers to oxygen produced at extreme ocean depths without the involvement of photosynthesis.
    • This process occurs in total darkness on the ocean floor, challenging the traditional understanding that sunlight is necessary for oxygen generation.
    • It was first discovered in 2024 by researchers studying deep-sea environments.
    • The strange nodules found at a depth of 13,000 feet act like natural batteries, splitting water molecules into oxygen and hydrogen using electrical charges.
    • These nodules function in areas where light does not penetrate, under extreme pressure and low-temperature conditions.
    • Occurrence:
      • Found in specific deep-sea zones, particularly in regions characterized by unique electrochemical activity.
      • Occurs in places previously considered incapable of supporting oxygen production.

    Features and Significance of Dark Oxygen:

    • Unlike traditional oxygen production, dark oxygen does not rely on photosynthesis or sunlight.
    • It is driven by electrochemical reactions occurring naturally in the ocean floor.
    • Strange nodules on the ocean floor possess an electric charge, enabling them to split water molecules into oxygen and hydrogen.
    • The process releases hydrogen, which could potentially serve as an energy source for microbial life in these regions.

    PYQ:

    [2012] Which one of the following sets of elements was primarily responsible for the origin of life on the Earth?

    (a) Hydrogen, Oxygen, Sodium

    (b) Carbon, Hydrogen, Nitrogen

    (c) Oxygen, Calcium, Phosphorus

    (d) Carbon, Hydrogen, Potassium