‘RNA interference (RNAi)’ technology has gained popularity in the last few years. Why

2019

“Genetics,Biotechnology”, Science and Technology

‘RNA interference (RNAi)’ technology has gained popularity in the last few years. Why?

1. It is used in developing gene silencing therapies.
2. It can be used in developing therapies for-the treatment of cancer.
3. It can be used to develop hormone replacement therapies.
4. It can be used to produce crop plants that are resistant to viral pathogens.

Select the correct answer using the code given below.

(a)

1, 2 and 4

(b)

2 and 3

(c)

1 and 3

(d)

1 and 4 only

Answer:

(a)

Newspaper/CA

Explanation

This novel approach opens new avenues for crop improvement by developing disease resistant, abiotic or biotic stress tolerant, and high yielding elite varieties. RNA interference (RNAi) is a mechanism for gene silencing. Such mechanism possesses an unusual ability in targeting cancer-related genes STATEMENT 3 IS INCORRECT. Due to its size and highly polyanionic (containing negative charges at several sites) nature, unmodified Small interfering RNA (siRNA) molecules cannot readily enter the cells through the cell membrane.