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  • Innovations in Biotechnology and Medical Sciences

    Zosurabalpin: Antibiotic against Drug-Resistant Bacteria

    5 January 2024 | Prelims Only | Science Tech
    Mains Paper 3: Awareness in various sc and tech fields

    Introduction

    • New Antibiotic Class: Researchers have identified zosurabalpin, a new class of antibiotics showing potential against the drug-resistant bacterium Acinetobacter baumannii.
    • Effective against CRAB: Zosurabalpin has been found effective against carbapenem-resistant Acinetobacter baumannii (CRAB)-induced pneumonia and sepsis in mouse models.

    About Zosurabalpin

    • Development Process: The antibiotic originated from a tethered macrocyclic peptide (MCP) selectively targeting A. baumannii and was optimized for efficacy and tolerability.
    • Novel Mode of Action: Zosurabalpin operates through a previously unknown mechanism, inhibiting the transport of lipopolysaccharide (LPS) in bacteria.
    • Inhibition of LPS Transport: By blocking a protein complex essential for LPS transport to the bacterial surface, zosurabalpin disrupts the outer membrane structure of Gram-negative bacteria, leading to bacterial death.

    Effectiveness and Clinical Trials

    • Laboratory and Animal Studies: Zosurabalpin demonstrated effectiveness against over 100 CRAB clinical samples in the lab and significantly reduced bacterial levels in mice with CRAB-induced pneumonia and sepsis.
    • Phase I Clinical Trials: The antibiotic has undergone evaluation in two phase I clinical trials, marking the initial steps towards potential human use.

    Implications and Future Prospects

    • Addressing Antibiotic Resistance: The discovery of zosurabalpin offers hope in the fight against antibiotic-resistant bacteria, a growing global health concern.
    • Potential Clinical Application: If further trials are successful, zosurabalpin could become a vital tool in treating infections caused by drug-resistant Acinetobacter baumannii.
    • Continued Research: Ongoing and future studies will be crucial to fully understand the antibiotic’s safety, efficacy, and potential resistance mechanisms.

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  • Telecom and Postal Sector – Spectrum Allocation, Call Drops, Predatory Pricing, etc

    [pib] Kochi-Lakshadweep Islands Submarine Optical Fiber Connection (KLI-SOFC) Project

    5 January 2024 | Prelims Only | Economics
    Mains Paper 3: Infrastructure: Energy, Ports, Roads, Airports, Railways Etc.

    kochi

    Introduction

    • The Prime Minister has inaugurated Kochi-Lakshadweep islands submarine optical fiber connection (KLI-SOFC) project.

    About KLI-SOFC Project

    • The KLI-SOFC project extends submarine cable connectivity from Kochi to eleven Lakshadweep Islands, including Kavaratti, Agatti, and Minicoy.
    • The project aims to provide high-speed wireline broadband connectivity through FTTH and 5G/4G Mobile networks to the Lakshadweep Islands population.
    • Funded by the Universal Services Obligation Fund (USOF), Department of Telecommunication.
    • The total link distance of the project is 1,868 kms.
    • Implementing agencies include BSNL as the Project Executing Agency and M/s NEC Corporation India Pvt Ltd for contract work.

    Benefits of the Project

    • Contributes to ‘Digital India’ and ‘National Broadband Mission’, enabling e-governance projects in Lakshadweep.
    • Boosts E-Governance, Tourism, Education, Health, Commerce, and Industries, potentially improving living standards and accelerating social and economic development.
    • The bandwidth created will be available to all Telecom Service Providers (TSPs) to enhance telecom services in the Lakshadweep Islands.

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  • Tiger Conservation Efforts – Project Tiger, etc.

    Tiger Sightings in Buxa National Park

    5 January 2024 | Prelims Only | Enviro & Biodiversity
    Mains Paper 3: Conservation, Environmental Pollution & Degradation, Eia

    buxa

    Introduction

    • Camera traps in the Buxa National Park, West Bengal captured images of a tiger, reigniting hopes among forest officials and experts.
    • The last sighting before December 2021 was 23 years ago, indicating the tiger’s absence from the reserve for decades.

    Buxa Tiger Reserve: Geography and Ecology

    Details
    Location Alipurduar district, West Bengal, India. Near the Bhutan border.
    Establishment Created in 1983 as a tiger reserve; declared a national park in January 1992.
    Area Total area of approx. 760 sq km (core area: 390 sq km, buffer zone: 370 sq km).
    Ecological Significance Part of the Eastern Himalayan subregion, known for its unique biodiversity.
    Geographical Connectivity Shares a northern boundary with Bhutan. Connected with Bhutanese forests, Kochugaon forests, Manas Tiger Reserve, and Jaldapara National Park.

    Reasons for the Tiger’s Return

    • Habitat Improvement: Efforts to reduce human interference, expand grasslands, and increase the prey base have created a more suitable habitat for tigers.
    • Conservation Measures: The introduction of chital (spotted deer) as prey and the creation of watering holes have been part of these efforts.

    Conservation Initiatives and Future Plans

    • Tiger Augmentation Project: Launched in 2018, this project involves the state forest department, Wildlife Institute of India, and the National Tiger Conservation Authority.
    • Village Relocation: Plans to relocate villages from the core area aim to reduce human presence and further improve the habitat.
    • Expert Insights: Scientists note the importance of habitat connectivity between Bhutan and Buxa and the reduction of human disturbances as key factors in attracting tigers back to Buxa.

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  • Labour, Jobs and Employment – Harmonization of labour laws, gender gap, unemployment, etc.

    Maharashtra approves option for Old Pension Scheme

    5 January 2024 | ExplainedPrelims Only | Governance
    Mains Paper 2: Government Scheme/Policies

    pension

    Introduction

    • The Maharashtra Cabinet has approved a proposal allowing certain state government employees to opt for the old pension scheme (OPS).
    • The option is extended to employees who joined the service after November 1, 2005, based on recruitment advertisements issued before that date.

    Transition in Pension Schemes

    • Old Pension Scheme (OPS): The OPS guaranteed a pension of half the last basic salary plus dearness allowance after a minimum of 10 years of service, without employee contributions. It also provided family pension and Death cum Retirement Gratuity (DCRG).
    • New Pension Scheme (NPS): Introduced to address the growing pension bill, the NPS is a market-linked, participatory scheme requiring contributions from both employees and employers.

    Background and Implementation of NPS

    • OASIS Project: Initiated in 1999, it led to the recommendation of the NPS by the Atal Bihari Vajpayee government in 2003.
    • Scheme Details: Employees contribute 10% of their basic salary, matched up to 14% by the employer. The funds are invested in PFRDA-regulated pension funds with market-linked returns.
    • Account Management: NPS provides a Permanent Retirement Account Number (PRAN) for lifelong account management.
    • State Adoption: All states except West Bengal have implemented the NPS. Some opposition-ruled states announced plans to revert to the OPS.

    Rationale Behind NPS Adoption

    • Pension Debt Sustainability: The OPS was a fiscal burden without accumulated funds, whereas the NPS relies on accumulated funds.
    • Addressing Ageing Population: With increasing life expectancy, the OPS became unsustainable.
    • Preventing Early Retirements: The NPS encourages longer service due to its long-term investment fund ideology.
    • Investment and Flexibility: NPS offers flexible investment options and the freedom to switch investment options and fund managers.

    Criticism of NPS

    • Market Risks: The exposure of retirement funds to market uncertainties raises concerns about old age security.
    • Pension Amount Concerns: There is no minimum pension guarantee, and pensions under NPS do not adjust for inflation.
    • Accountability Issues: Questions remain about the security of the invested corpus and accountability in market failures.

    Conclusion

    • State Governments’ Challenge: Reverting to OPS requires careful consideration of financial implications on future generations.
    • Review and Strengthening of NPS: Measures such as introducing inflation-indexed annuities, assuring minimum returns, and ensuring timely registration and contributions can strengthen the NPS.
    • Balanced Approach: A nuanced approach is needed to balance fiscal sustainability with providing adequate social security to retirees.

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  • Capital Markets: Challenges and Developments

    Decoding the Adani-Hindenburg Judgment

    5 January 2024 | Prelims OnlySC Judgements | Economics
    Mains Paper 3: Indian Economy

    Introduction

    • Recent Order: The Supreme Court’s recent order on the Adani-Hindenburg matter focused on the inquiries conducted by the Securities and Exchange Board of India (SEBI).
    • No Regulatory Failure Found: The apex court concluded that there was no regulatory failure on SEBI’s part, negating the need for a Special Investigating Team (SIT).

    SEBI’s Investigations and the Supreme Court’s Stance

    • Status of Investigations: Out of 24 investigations related to the Adani-Hindenburg matter, SEBI has completed 22.
    • Supreme Court’s Trust in SEBI: The court accepted SEBI’s status report without delving into the details of the investigations, trusting SEBI to bring them to a logical conclusion.

    Concerns and Criticisms of the Supreme Court Judgment

    • Lack of Transparency: The findings of the completed SEBI investigations have not been made public, raising questions about the transparency and accountability of the process.
    • ‘Chicken-and-Egg’ Inquiry: The Supreme Court did not address the “chicken-and-egg situation” where SEBI’s inability to identify the ultimate beneficial owners of certain overseas entities has stalled the investigation.
    • Overlooked Statutory Violations: The judgment did not consider the alleged dilution of regulations that could facilitate the concealment of beneficial ownership, which might be violative of the SEBI Act.

    Implications of the Judgment

    • Continued SEBI Investigation: SEBI has been given an additional three months to conclude its inquiry into the alleged violation of minimum shareholding norms by the Adani group companies.
    • Potential Subversion of Ongoing Investigations: The deficiencies in the Supreme Court judgment could potentially undermine the ongoing investigations into the Adani group.
    • Hindenburg and OCCRP Reports: The judgment has seemingly dismissed the reports by Hindenburg and OCCRP as unrelated or inconclusive, despite their revelations about the Adani group’s financial dealings.

    Historical Context and Ongoing Concerns

    • Past Allegations: The Adani group has faced similar allegations of share price manipulation and round-tripping in the past, with SEBI itself filing a criminal complaint 15 years ago.
    • Current Investigations: Despite ongoing investigations for over three years, no criminal complaint has been registered against the Adani promoters for the recent allegations.

    Conclusion

    • Need for Reevaluation: The deficiencies in the Supreme Court judgment warrant a reconsideration in the interest of justice and transparency.
    • Public Interest and Justice: Ensuring that the findings of SEBI’s investigations are made public and acted upon is crucial for upholding regulatory integrity and public trust.
    • Future of Adani Investigations: The outcome of the ongoing SEBI investigations and the handling of the Hindenburg and OCCRP reports will be pivotal in determining the course of justice in this high-profile case.

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  • International Space Agencies – Missions and Discoveries

    [pib] India to participate in Square Kilometer Array (SKA) Project    

    5 January 2024 | Prelims Only | Science Tech
    Mains Paper 3: Awareness in various sc and tech fields

    square kilometer array ska

    Introduction

    • India will contribute Rs 1,250 crore to the multinational Square Kilometer Array (SKA) project, a significant international astronomical collaboration.

    Square Kilometer Array (SKA) Project: An Overview

    • Construction Phases: The SKA project is being built in two phases, with the first phase (SKA1) having commenced in December 2022.
    • Project’s Headquarters: The SKA project is headquartered at the Jodrell Bank Observatory in the UK.
    • Site Location: It involves constructing telescope arrays in Australia and South Africa, aiming to map galaxies and explore the universe with unprecedented detail.
    • Operational Timeline: SKA1 is expected to begin operations by 2029.

    Design and Features of the SKA Telescopes

    • Array Composition: The SKA will consist of 197 parabolic radio antennae in South Africa and 131,072 low-frequency antennae in Australia.
    • Antennae Design: The design includes parabolic dishes and dipole antennae capable of detecting faint radio signals from vast distances.
    • Spatial Arrangement: The dishes and antennae will be strategically placed over large areas to calibrate the origin of observed signals effectively.

    Global Collaboration in the SKA Project

    • Consortium Members: The SKA Observatory (SKAO) includes 16 member countries, such as Australia, South Africa, Canada, China, India, Japan, and several European nations.
    • Frequency Range: The South African array will focus on mid-frequency signals, while the Australian telescope will cover low-frequency ranges.
    • Expansion Plans: Additional dishes are planned in neighbouring African countries to enhance the project’s data triangulation and resolution capabilities.

    Scientific Objectives of the SKA

    • Exploring the Universe: The SKA will observe and map galaxies at the edge of the observable universe, providing insights into galaxy formation and evolution.
    • Studying the ‘Dark Ages’: The telescope will delve into the early universe’s ‘Dark Ages’ and investigate phenomena like dark matter and dark energy.
    • Search for Extraterrestrial Life: The SKA will also contribute to the search for life beyond Earth by examining habitable zones around stars.

    India’s Role  

    • Pathfinder Research Partner: India’s Giant Metrewave Radio Telescope, operated by the National Centre for Radio Astrophysics (NCRA) of Tata Institute of Fundamental Research (TIFR), is a key partner in the project.
    • Consortium Involvement: The SKA India consortium comprises over 20 colleges and universities across India, contributing to various aspects of the project.

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  • Artificial Intelligence (AI) Breakthrough

    How AI is changing what sovereignty means

    5 January 2024 | op-ed snap | Science Tech
    Mains Paper 3: Awareness in various sc and tech fields

     

    The Geopolitics Of Artificial Intelligence

    Central Idea:

    • The global landscape witnesses a complex interplay of power dynamics in AI and frontier technologies. Efforts by international bodies like the United Nations set ethical frameworks for responsible AI development.

    Key Highlights:

    • UN initiatives on AI governance and ethical principles.
    • Rise of “digital sovereignty” challenging traditional notions of territorial sovereignty.
    • Emergence of contrasting “digital empires,” with the US favoring a free market approach and China leaning towards state-driven regulation.
    • Concerns about China’s regulatory model spreading globally due to its technological success and political control.
    • The EU advocating for a human rights-based approach to AI development.

    Key Challenges:

    • Threats to privacy and democracy due to the manipulation of personal information by AI tools.
    • Tension between the free market approach and authoritarian regulatory models.
    • Potential dominance of China’s oppressive regulatory model in the global AI landscape.

    Key Terms:

    • Digital sovereignty
    • Techno-optimism
    • Authoritarian regulatory model
    • Surveillance capitalism
    • Lethal autonomous weapons systems (LAWs)

    Key Phrases:

    • “Digital sovereignty” transforming territorial sovereignty.
    • “Digital empires” in complicity and collision.
    • “Techno-optimism run wild” leading to an appeal for authoritarian regulatory reach.
    • “Surveillance capitalism” and “digital authoritarianism” shaping the uncertain future of the technopolitical.

    Key Quotes:

    • “Privacy, anonymity, and autonomy remain the main casualties of AI’s ability to manipulate choices.”
    • “China’s regulatory model will prevail, normatively and descriptively.”
    • “Whether surveillance capitalism, digital authoritarianism, or liberal democratic values will prevail remains uncertain.”

    Key Examples and References:

    • UNICEF hosting a joint session on AI governance.
    • The US and China as contrasting digital empires.
    • EU Declaration on Development advocating a human rights-based approach.

    Key Facts:

    • Social media industry growth from $193.52 billion in 2001 to $231.1 billion in 2023.
    • Concerns about the impact of China’s technological success combined with political control on global AI governance.

    Way Forward:

    • Continued efforts to humanize AI applications in civil and military contexts.
    • Global collaboration to establish norms and frameworks for responsible AI development.
    • Vigilance against the potential spread of oppressive regulatory models, emphasizing human rights and inclusivity.

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  • Urban Transformation – Smart Cities, AMRUT, etc.

    Breaking new ground the Kerala way

    5 January 2024 | op-ed snap | Economics
    Mains Paper 1: Urbanization, Their Problems & Remedies

    Kerala Cabinet decides to constitute Kerala Urban Policy Commission - The Hindu

    Central Idea:

    • The article discusses the formation of the Kerala Urban Commission in the context of global urbanization trends and the need for a comprehensive approach to urban development.
    • It highlights the challenges faced by urban areas in India and emphasizes the significance of revisiting and re-evaluating urban policies.

    Key Highlights:

    • The article reflects on the historical development phases of urbanization in post-independent India, noting the failures of both Nehruvian centralized planning and the subsequent privatization trends in the 1990s.
    • It underscores the necessity of understanding objective patterns of urbanization, focusing on migration, settlement patterns, and the role of information technology.
    • Governance issues in cities, such as delayed transfer of subjects to municipalities and the debate on having managers instead of elected officials, are highlighted.
    • The article suggests that existing urban missions, like Swachh Bharat and Smart Cities, have failed to produce desired results and may continue to do so.

    Key Challenges:

    • Piecemeal approaches to urban development are criticized for their failure to address the complex realities of urbanization.
    • Governance issues, including the delay in transferring subjects to municipalities and the debate on city affairs management, pose challenges to effective urban governance.
    • The article suggests that existing urban missions, like Swachh Bharat and Smart Cities, have failed to produce desired results and may continue to do so.

    Key Terms:

    • Urban Commission: Refers to the proposed or existing bodies tasked with addressing the challenges and complexities of urban development.
    • Urbanization: The process of population migration from rural to urban areas, leading to the growth and development of cities.
    • Nehruvian Period: Refers to the development era influenced by Jawaharlal Nehru’s centralized planning approach.
    • Privatization: The transfer of control or ownership of public services or assets to private entities.
    • Fifteenth Finance Commission: A reference to the commission responsible for recommending the distribution of financial resources between the central and state governments.

    Key Phrases:

    • “Holistic city approach”: Refers to a comprehensive and integrated strategy for urban development.
    • “Engines of growth”: Describes the shift in cities’ perception from spaces of enlightenment to centers focused on economic development.
    • “Mission mode of development”: Refers to project-oriented approaches like the Jawaharlal Nehru National Urban Renewal Mission and Smart Cities Mission.
    • “Complex processes unfolding”: Highlights the intricate nature of governance and financial structures in urban areas.

    Key Quotes:

    • “Cities were made competitive and termed as ‘engines of growth’ — not spaces of enlightenment, future of dreams, and habitat.”
    • “The urbanisation process cannot be reduced to some mission approaches…”
    • “Kerala Urban Commission can be the lighthouse for other States…”

    Key Statements:

    • “An urban commission is required at the national and State levels to understand some of the interesting objective patterns of urbanisation.”
    • “The period of the 1990s is the one where the abject privatization of cities began…”

    Cabinet clears formation of urban commission- The New Indian Express

    Key Examples and References:

    • Mention of the National Commission on Urbanisation formed by Rajiv Gandhi and its recommendations.
    • Reference to global urbanization trends, including the impact on climate change and unequal city spaces.
    • Examples of failed urban missions like Swachh Bharat and Smart Cities.

    Key Facts:

    • More than half of the world’s population (56%) currently lives in cities.
    • Kerala’s urbanized population is estimated to be around 90%.
    • The Nehruvian period witnessed the construction of around 150 new towns with a centralized planning approach.

    Key Data:

    • The 74th Constitutional Amendment marked a shift towards more private initiative and investment in urban development.
    • The Kerala Urban Commission has a 12-month mandate to address urbanization challenges and lay a roadmap for 25 years of urban development.

    Critical Analysis:

    • The article critically examines the historical phases of urban development in India and highlights the shortcomings of past approaches.
    • It questions the effectiveness of existing urban missions and emphasizes the need for a holistic understanding of urbanization processes.
    • Governance issues and financial centralization are critically discussed as impediments to successful urban development.

    Way Forward:

    • The article suggests that the formation of the Kerala Urban Commission could serve as a model for other highly urbanized states.
    • It advocates for a comprehensive and objective approach to urban development, emphasizing the importance of addressing challenges such as migration, settlement patterns, and information technology.
    • The need for revisiting and relooking at urban policies is underscored for a more successful and sustainable urban future.

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  • Civil society under siege, in India

    5 January 2024 | op-ed snap | Indian Society
    Mains Paper 1: Communalism, Secularism, Regionalism

    COMMUNALISM IN INDIA (KEY POINTS TO REMEMBER) - Achievers IAS Classes

    Central Idea:

    • The article discusses the threats faced by India’s civic space, particularly organizations fighting against communalism. Emphasizes the importance of protecting constitutional freedoms.

    Key Highlights:

    • Constitutional freedoms are under siege in India’s diverse and vibrant civil society.
    • Organizations actively fighting communalism are facing severe attacks, affecting their funding and leadership.
    • The state employs various instruments, including legal charges, amendments to laws, and tax-related measures, to curb civic space.
    • Impact is significant on organizations supporting minority, Dalit, Adivasi rights, and equity promotion.

    Key Challenges:

    • High-intensity attacks leading to financial constraints and imprisonment for leaders of certain NGOs.
    • Shrinking civic space even for neutral or non-communal organizations.
    • Utilization of legal instruments like money laundering charges and investigations to intimidate NGOs.
    • Amendments to laws, such as the FCRA, restricting access to foreign funds for NGOs.
    • Intimidation of domestic donors through tax-related provisions.

    Key Terms/Phrases:

    • Civic space
    • Constitutional freedoms
    • Anti-communal
    • NGOs (Non-Governmental Organizations)
    • FCRA (Foreign Contribution Regulation Act)
    • Money laundering charges
    • Civic mobilization
    • Secularism
    • Adivasi rights
    • Human rights causes

    Key Quotes/Statements:

    • “The last bastion and ray of hope for India’s democracy is its civic space.”
    • “The scale of attack on organizations actively fighting against communalism is alarming.”
    • “The state employs a range of instruments to limit the civic space of various organizations.”

    Key Examples and References:

    • Amnesty International, Centre for Equity Studies, Citizens for Justice and Peace, among others, facing severe attacks.
    • Greenpeace transitioning from high-intensity attacks to a lower level.

    Key Facts/Data:

    • Amendments to the FCRA in 2010 and 2020 impacted around 18,000 NGOs between 2015 and 2022.
    • The 2020 amendments to the Income-Tax Act make renewals of NGO certificates mandatory every five years.
    • The Central Bureau of Investigation (CBI) is empowered to investigate NGOs under the FCRA.

    Critical Analysis:

    • The article presents a critical analysis of the state’s tactics to limit civic space, affecting organizations fighting against communalism.
    • It highlights the severity of attacks and the broader impact on democratic values.

    Way Forward:

    • Strengthening opposition and regional leaders who take a clear secular position.
    • Mobilizing anti-communal and progressive civic space to safeguard democracy.
    • Advocating for the protection of constitutional freedoms and reviewing stringent laws impacting NGOs.
    • Raising awareness about the importance of civic space in preserving India’s democracy.

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  • Mission Clean Ganga

    Project ‘Devika’: North India’s First River Rejuvenation nears completion

    4 January 2024 | Prelims Only | Governance
    Mains Paper 2: Government Scheme/Policies

    Introduction

    • North India’s first river rejuvenation project, ‘Devika’, is nearing completion and will soon be inaugurated by Prime Minister.

    About Project ‘Devika’

    • Initiation: Launched in February 2019 by the PM, the project is modelled after the ‘Namami Ganga’ initiative.
    • Demand: The project, long demanded for renovation and rejuvenation, gained momentum after 2014, marking a significant development in river rejuvenation efforts in North India.
    • Project Execution: The Urban Environmental Engineering Department (UEED) of J&K is responsible for the LWM project’s construction.
    • Cultural Importance: The Devika River, revered as the sister of the sacred Ganges, holds great religious significance, particularly in Udhampur, Jammu & Kashmir.

    Key Features  

    • Liquid Waste Management (LWM): A separate LWM project is being implemented to maintain the river’s sanctity, involving a network of pipes and manholes connecting households.
    • Solid Waste Management (SWM): Alongside LWM, an SWM project is integral to preserving the river’s sanctity.
    • Infrastructure Development: The project includes three sewage treatment plants, a 129.27 km sewerage network, the development of cremation ghats, protection fencing, landscaping, and the establishment of small hydropower and solar power plants.

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