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GS Paper: GS3-16.Achievements of Indians in Science & Technology

  • International Thermonuclear Experimental Reactor (ITER) Project

    The heavy engineering division of L&T dispatched a giant Cryostat lid, to International Thermonuclear Experimental Reactor (ITER) site in France from its Hazira unit in Gujarat.

    Try this MCQ:

    Q.With reference to International science projects, consider the following:

    1. Large Hadron Collider (LHC)– The God Particle
    2. Thirty Metre Telescope (TMT) – The World’s Most Advanced Telescope
    3. International-Thermonuclear-Experimental-Reactor (ITER) – Fusion Energy
    4. Facility for Antiproton and Ion Research (FAIR) – Antiproton and Ion Research

    Which of the above projects have India’s active participation?

    a) 1 only

    b) 2 and 3 only

    c) 1, 3 and 4 only

    d) All of them

    ITER Project

    • ITER is international nuclear fusion research and engineering megaproject, which will be the world’s largest magnetic confinement plasma physics experiment.
    • The goal of ITER is to demonstrate the scientific and technological feasibility of fusion energy for peaceful use.

    Minutes of the project

    • The project is funded and run by seven member entities—the European Union, India, Japan, China, Russia, South Korea and the United States.
    • The EU, as host party for the ITER complex, is contributing about 45 per cent of the cost, with the other six parties contributing approximately 9 per cent each.
    • Construction of the ITER Tokamak complex started in 2013 and the building costs were over US$14 billion by June 2015.

    How does it work?

    • ITER is the most complex science project in human history. The ITER aims to use a strong electric current to trap plasma inside a doughnut-shaped enclosure long enough for fusion to take place.
    • Hydrogen plasma will be heated to 150 million degrees Celsius, ten times hotter than the core of the Sun, to enable the fusion reaction.
    • The process happens in a doughnut-shaped reactor, called a tokamak 1, which is surrounded by giant magnets that confine and circulate the superheated, ionized plasma, away from the metal walls.
    • The superconducting magnets must be cooled to -269°C (-398°F), as cold as interstellar space.
    • Scientists have long sought to mimic the process of nuclear fusion that occurs inside the sun, arguing that it could provide an almost limitless source of cheap, safe and clean electricity.
    • Unlike in existing fission reactors, which split plutonium or uranium atoms, there’s no risk of an uncontrolled chain reaction with fusion and it doesn’t produce long-lived radioactive waste.

    Back2Basics: Nuclear Fusion

    • Nuclear fusion is the process of making a single heavy nucleus (part of an atom) from two lighter nuclei. This process is called a nuclear reaction.
    • The nucleus made by fusion is heavier than either of the starting nuclei. It releases a large amount of energy.
    • Fusion is what powers the sun. Atoms of Tritium and Deuterium (isotopes of hydrogen, Hydrogen-3 and Hydrogen-2, respectively) unite under extreme pressure and temperature to produce a neutron and a helium isotope.
    • Along with this, an enormous amount of energy is released, which is several times the amount produced by fission.
    • Scientists continue to work on controlling nuclear fusion in an effort to make a fusion reactor to produce electricity.

    How it is different from nuclear fission?

    • Simply put, fission is the division of one atom into two (by neutron bombardment), and fusion is the combination of two lighter atoms into a larger one (at a very high temperature).
    • Nuclear fission takes place when a large, somewhat unstable isotope (atoms with the same number of protons but a different number of neutrons) is bombarded by high-speed particles, usually neutrons.

  • Celebrating the contributors to agriculture

    This article introduces us to the Indian winners of the prize that is considered as the Nobel for research in food. Their contribution has benefited agriculture immensely.Here, we’ll get a brief idea about their work.

    Word Food Prize

    • The World Food Prize is often described as the Nobel for research in food.
    • It was set up by Ñorman Borlaug.
    • Borlaug won the Nobel Peace Prize in 1972 for his work on hybridisation of wheat and rice.
    • His work led to the Green Revolution in the mid-1960s.

    Indian winners of the award

    • The awards to eight Indians of the total of 50 given so far are a tribute to the country’s agricultural university education and research system.
    • The country should celebrate their achievements unabashedly when 7-10 million new productive jobs need to be created annually.
    • And when it accounts for a third of global undernourished.
    • The COVID-19 pandemic has made job creation and improved nutrition and health more urgent than ever.

    Let’s look at the contributions made by these personalities

     Rattan Lal

    • Rattan Lal was awarded for developing and mainstreaming a soil-centric approach to increasing food production.
    • This approach also restores and conserves natural resources and mitigates climate change.
    • His research has shown that growing crops on healthy soils produces more food from less land area, less use of agrochemicals, less tillage, less water, and less energy.

    M S Swaminathan

    • Swaminathan’s vision transformed India from a “begging bowl” to a “breadbasket” almost overnight.
    • His work helped bringing the total crop yield of wheat from 12 million tonnes to 23 million tonnes in four crop seasons.
    • Which helped in ending India’s dependence on grain imports.

    Verghese Kurien

    • Kurien, received the prize in 1989 for India’s white revolution.
    • Under his leadership, milk production increased from 23.3 million tonnes (1968-69) to 100.9 million tonnes (2006-07).
    • And now it is projected to reach 187 million tonnes for 2019-20.
    • This helped in bringing millions of small and marginal farmers, including women into the marketplace.

     Ramlal Barwale

    • Barwale, a small farmer and entrepreneur, received the award in 1996.
    • He made selling seeds of okra and sorghum “hip” and founded the Maharashtra Hybrid Seeds Company.
    • The Crop Science Society of America has called him father of the seed industry in India.
    • He introduced hybrid rice from China to India.

    Surinder Vasal

    • Vasal was given the prize in 2000 for developing quality protein maize (QPM).
    • Integrating cereal chemistry and plant breeding techniques, Vasal and Villegas of Mexico collaborated to work on “opaque-2” maize variety using molecular biology techniques.
    • In the mid-1980s, they produced a QPM germplasm with hard kernel characteristics and taste like that of the traditional grain.
    • But it has much higher quality levels of lysine and tryptophan, thereby enhancing the nutrition value.

    Mododugu Gupta

    • Gupta received the award in 2005 for starting a blue revolution.
    • He developed two exceptional approaches for increasing fish harvests among the very poor.
    • This helped in increasing the protein and mineral content in the diets of over one million of the world’s most impoverished families.
    •  Gupta’s aquaculture technologies boosted Bangladesh’s fish yields from 304 kg per hectare to over 2,500 kg per hectare in less than a year — including 1,000 kg per hectare harvests in the dry season.

    Sanjaya Rajaram

    • Rajaram, who won the prize in 2014.
    • He succeeded Borlaug in leading CIMMYT’s wheat breeding programme.
    • There he went on to develop an astounding 480 varieties that have been widely adopted by both small and large-scale farmers.
    • Rajaram was born near a small farming village in Uttar Pradesh and received his master’s degree from IARI.

    Decreasing government support

    • The awardees all come from the time of the green and rainbow revolutions (of dairy and aqua-culture).
    • It was also the time when India invested heavily in agricultural science education and research and Indian scientists shone brightly in the global galaxy of science.
    • Government support for state agricultural universities, and research conducted by the ICAR and the departments of science and technology and biotechnology has slipped in recent years.
    • Today, not a single Indian university is counted among the top 100 in the world.
    Consider the question asked by the UPSC in 2019 “How was India benefitted from the contributions of Sir M.Visvesvaraya and Dr M. S. Swaminathan in the fields of water engineering and agricultural science respectively?”

    Conclusion

    Students and faculty at ICAR and state agricultural universities can follow in their footsteps and achieve scientific excellence, if they receive the resources and their work is supported with incentives.

  • Nature Index, 2020

    India has ranked twelfth, globally in science research output as per the recently-released Nature Index table 2020. The top five positions have gone to the United States of America, China, Germany, United Kingdom and Japan.

    Note: This nature index has nothing to do with nature conservation. It has only mentioned the rankings of research institutes in natural and physical sciences.

    What is the Nature Index?

    • The Nature Index is a database of author affiliation information collated from research articles published in an independently selected group of 82 high-quality science journals.
    • It serves as an indicator of high-quality research in the Natural and Physical Sciences.
    • The database is compiled by Nature Research, a division of the international scientific publishing company Springer Nature that publishes academic journals.
    • The index provides a close to the real-time proxy of high-quality research output and collaboration at the institutional, national and regional level.

    India’s achievements

    • Globally the top-rated Indian institutions in this list are CSIR, a group of 39 institutions at the 160th position and IISc Bangalore at the 184th
    • Three of the autonomous institutions of the DST have found their place among the top 30 Indian Institutions.
    • Keeping out CSIR, which is a cluster of institutions, IACS Kolkata is among the top three institutions in quality Chemistry Research in India.
    • NCASR Banglore ranks 4th among academic institutions in life sciences, 10th in Chemistry and Physical Sciences, 10th among Indian academic institutions, and 469th in the global ranking.

  • Spirulina Groundnut Chikki to boost immunity

    The Mysuru-based Central Food Technological Research Institute, CFTRI has developed Spirulina groundnut Chikki that can provide micro-nutrients and boost the immunity of people during this time of the pandemic.

    Beware, the Chikki so mentioned has no GI tag. What makes it significant is the Spirulina, a photosynthetic bacteria, which is suitable for human consumption.

    Spirulina Groundnut Chikki

    • It is a snack that provides good micro-nutrients.
    • It has used Spirulina as well as the tasty, nourishing groundnuts to prepare Chikki that is rich in micro-nutrients such as Vitamin A, Beta Carotene and easily digestible algal proteins.
    • Other nutritious snacks of CFTRI such as Nutri mango fruit bar and cardamom flavoured water is also part of the food items supplied to the migrant labourers.
    • The mango bar is rich with carbohydrates, carotene, Vitamin C and Zinc to improve the immunity.
    • Cardamom flavoured water with traditional herbs to have immune booster qualities.

    What is Spirulina?

    • Spirulina is an organism that grows in both fresh and saltwater.
    • It is a type of cyanobacteria, which is a family of single-celled microbes that are often referred to as blue-green algae.
    • It is used as a dietary supplement or whole food. It is also used as a feed supplement in the aquaculture, aquarium, and poultry industries.
    • Just like plants, cyanobacteria can produce energy from sunlight via a process called photosynthesis.

  • Pokhran-II nuclear tests

    Yesterday, May 11 was celebrated as the National Technology Day. It marks the day on which India successfully test-fired its first nuclear bombs in 1998.

    Practice question for mains

    Q. India’s nuclear policy of ‘No First Use’ needs a revamp. Examine.

    India and nuclear weapons

    • India is currently among eight countries in the world that have a publicly known nuclear weapons program.
    • At the time of our independence, leaders were opposed to fully embracing nuclear weapons.
    • Just two years before in 1945, the world had witnessed the horrific nuclear bombings of Hiroshima and Nagasaki.
    • Mahatma Gandhi called the use of nuclear weapons morally unacceptable.

    Why India did equip itself with nuclear arms?

    • Then PM Jawaharlal Nehru was sceptical but kept the door open for future consideration.
    • This future beckoned early, as India’s defeat in the 1962 Sino-Indian War gave rise to legitimate fears about national security.
    • Then in 1974, India conducted its first nuclear test, codenamed “Smiling Buddha”, at Pokhran in Rajasthan.
    • Then-Prime Minister Indira Gandhi called the test a peaceful nuclear explosion.
    • India demonstrated to the world that the country could defend itself in an extreme situation and chose not to immediately weaponize the nuclear device it tested at Pokhran.

     The Pokhran II tests

    • India’s fence-sitting finally ended when it detonated another device in 1998, again at Pokhran.
    • Assigned the code name Operation Shakti, the mission was initiated on May 11, 1998.
    • The tests consisted of 5 detonations, the first being a fusion bomb while the remaining four were fission bombs.
    • One fusion and two fission bombs were tested on May 11, and two more fission bombs on May 13.
    • With the tests, India achieved its objective of building fission and thermonuclear weapons with yields up to 200 kilotons.

    Aftermath

    • After Pokhran-II, Vajpayee had declared India a nuclear state — then the sixth country in the world to join this league.
    • Unlike in 1974, India had this time chosen to actively develop its nuclear capabilities, and the tests followed economic sanctions by the United States and Japan. The sanctions were later lifted.

    Back2Basics: India’s nuclear programme

    • India started its own nuclear programme in 1944 when Homi Jehangir Bhabha founded the Tata Institute of Fundamental Research.
    • Physicist Raja Ramanna played an essential role in nuclear weapons technology research; he expanded and supervised scientific research on nuclear weapons and was the first directing officer of the small team of scientists that supervised and carried out the test.
    • After independence, PM Nehru authorised the development of a nuclear programme headed by Homi Bhabha.
    • The Atomic Energy Act of 1948 focused on peaceful development.
    • India was heavily involved in the development of the Nuclear Non-Proliferation Treaty but ultimately opted not to sign it.
    • In 1954, two important infrastructure projects were commissioned. The first established Trombay Atomic Energy Establishment at Mumbai (Bombay). The other created a governmental secretariat, Department of Atomic Energy (DAE), of which Bhabha was the first secretary.

    Nuclear Suppliers Group (NSG)

    • The NSG is a multilateral export control regime and a group of nuclear supplier countries that seek to prevent nuclear proliferation by controlling the export of materials, equipment and technology that can be used to manufacture nuclear weapons.
    • The NSG was founded in response to the Indian nuclear test in May 1974 and first met in November 1975.
    • It was solely aimed to deny advanced technology, and isolate and contain India.

  • Indigenous antibody test: COVID Kavach ELISA

    Indian Council of Medical Research (ICMR)-National Institute of Virology (NIV) at Pune has developed and validated the indigenous IgG ELISA test “COVID KAVACH ELISA” for antibody detection for COVID-19.

    Our thumb rule suggests that the ELISA test is being used only for the diagnosis of HIV infection. Right?

    But the ELISA test is a broader term to diagnose antibody-antigen interaction after certain virus infection to a person.  UPSC can test your basic knowledge of core biology with a question based on this concept.

    What is ELISA test?

    • ELISA (enzyme-linked immunosorbent assay) is a plate-based assay technique designed for detecting and quantifying substances such as peptides, proteins, antibodies and hormones.
    • Other names, such as enzyme immunoassay (EIA), are also used to describe the same technology.
    • In an ELISA, an antigen must be immobilized on a solid surface and then complexed with an antibody that is linked to an enzyme.
    • Detection is accomplished by assessing the conjugated enzyme activity via incubation with a substrate to produce a measurable product.
    • The most crucial element of the detection strategy is a highly specific antibody-antigen interaction.

    What are antibodies?

    • An antibody is a large, Y-shaped protein produced mainly by plasma cells that are used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.
    • There are five immunoglobulin classes (isotypes) of antibody molecules found in serum: IgG, IgM, IgA, IgE and IgD.
    • They are distinguished by the type of heavy chain they contain.

    Application of ELISA

    • Presence of antigen or the presence of antibody in a sample can be evaluated
    • Determination of serum antibody concentrations in a virus test
    • Used in the food industry when detecting potential food allergens
    • Applied in disease outbreaks- tracking the spread of disease e.g. HIV, bird flu, common, colds, cholera, STD etc

    Significance

    • Robust antibody tests are critical for surveillance to understand the proportion of the population exposed to infection.
    • The test will have the advantage of testing 90 samples together in a single run of 2.5 hours.
    • Moreover, ELISA based testing is easily possible even at the district level as the ELISA kit has an inactivated virus.
    • There are also minimal bio-safety and bio-security requirements as compared to the real-time RT-PCR test.
    • The test has the advantage of having much higher sensitivity and specificity as compared to the several rapid test kits which have recently flooded the Indian market.

    Limitations

    • Since the ELISA test is based on the detection of antibodies, it can only help in knowing if the person has been previously infected by a coronavirus.
    • It takes one-three weeks for the antibodies to develop in response to infection.
    • So, if a person who has been recently infected by the virus is tested during the window period (the time taken to develop antibodies) the result will turn out to be negative.
    • But a repeat test after a couple of weeks will indicate the true infection status.

    How it is different from the PCR test?

    • While the RT-PCR, which detects the RNA of the coronavirus, enables detection of current infection, it will not be useful if the testing is carried out days after the infection clears as the virus will no longer be present.
    • However, antibodies developed in response to the coronavirus infection will be present in the blood for a longer duration and hence the ELISA test can help detect past infection.
    • The maximum time the antibodies will be present in the body is not known for coronavirus.

    Back2Basics: Reverse Transcriptase – Polymerase Chain Reaction (PCR) Test

    • It uses a technique that creates copies of a segment of DNA. ‘Polymerase’ refers to the enzymes that make the copies of DNA.
    • Kary Mullis, the American biochemist who invented the PCR technique, was awarded the Nobel Prize for Chemistry in 1993.
    • The ‘chain reaction’ is how the DNA fragments are copied, exponentially — one is copied into two, the two are copied into four, and so on.
    • However, SARS-COV-2 is a virus made of RNA, which needs to be converted into DNA. For this, the technique includes a process called reverse transcription.
    • A ‘reverse transcriptase’ enzyme converts the RNA into DNA. Copies of the DNA are then made and amplified.
    • A fluorescent DNA binding dye called the “probe” shows the presence of the virus. The test also distinguishes SARS-COV-2 from other viruses.

  • Mobile Virology Research and Diagnostics Laboratory (MVRDL)

    The Defence Research and Development Organisation (DRDO) has developed a mobile virology research lab.

    We can expect a  prelim question on BSL ratings as the term is widely appearing in news these days.

    About the MVRDL

    • The MVRDL is the combination of a bio-safety level (BSL)-3 lab and a BSL-2 lab and was set up in a record time of 15 days.
    • It can process 1,000-2,000 samples a day.
    • The mobile lab will be helpful in carrying out a diagnosis of COVID-19 and in virus-culturing for drug screening, convalescent plasma-derived therapy, comprehensive immune profiling of patients towards vaccine etc.

    What are Biosafety Level (BSL) Ratings?

    • A BSL is a set of biocontainment precautions required to isolate dangerous biological agents in an enclosed laboratory facility.
    • The levels of containment range from the lowest biosafety level 1 (BSL-1) to the highest at level 4 (BSL-4).
    • BSL-1 is suitable for work with well-characterized agents which do not cause disease in healthy humans.
    • BSL- 2 is suitable for work involving agents of the moderate potential hazard to personnel and the environment.
    • BSL-3 is appropriate for work involving microbes which can cause serious and potentially lethal disease via the inhalation route.
    • BSL-4 is the highest level of biosafety precautions and is appropriate for work with agents that could easily be aerosol-transmitted within the laboratory and cause severe to fatal disease in humans for which there are no available vaccines or treatments.

  • [pib] CollabCAD tool to create 3D Computer Aided Designs

    Atal Innovation Mission, NITI Aayog and National Informatics Centre (NIC) jointly launched CollabCAD.

    CollabCAD

    • It is a computer-enabled software system which provides a total engineering solution from 2D drafting & detailing to 3D product design.
    • It helps the user to build models in virtual 3d space and create and engineering drawings for the shop floor which makes it a complete package for smart manufacturing.
    • The aim of this initiative is to provide a great platform to students of Atal Tinkering Labs (ATLs) across the country to create and modify 3d designs with free flow of creativity and imagination.
    • This software would also enable students to create data across the network and concurrently access the same design data for storage and visualization.

    Back2Basics: Atal Innovation Mission (AIM)

    • The Atal Innovation Mission (AIM) is a flagship initiative set up by the NITI Aayog to promote innovation and entrepreneurship across the length and breadth of the country.
    • AlM’s objectives are to create and promote an ecosystem of innovation and entrepreneurship across the country at school, university, research institutions, MSME and industry levels.
    • At the school level, AIM establishes Atal Tinkering Labs (ATL) in all districts across India. ATLs provide tinkering spaces to children to hone their innovative ideas and creativity.
    • At the university, NGO, SME and Corporate industry levels, AIM is setting up world-class Atal Incubators (AICs) that would trigger and enable successful growth of sustainable startups in every sector.

  • Sodium Hypochlorite as Coronavirus disinfectant

    In Uttar Pradesh, migrant workers travelling to their home states, or their belongings, were sprayed with a disinfectant, apparently to sanitise them.  The chemical in the spray was a sodium hypochlorite solution.

    Sodium hypochlorite

    • Sodium hypochlorite is commonly used as a bleaching agent, and also to sanitise swimming pools.
    • As a common bleaching agent, sodium hypochlorite is used for a variety of cleaning and disinfecting purposes.
    • It releases chlorine, which is a disinfectant. Large quantities of chlorine can be harmful.
    • The concentration of the chemical in the solution varies according to the purpose it is meant for.
    • A normal household bleach usually is a 2-10% sodium hypochlorite solution.
    • At a much lower 0.25-0.5%, this chemical is used to treat skin wounds like cuts or scrapes. An even weaker solution (0.05%) is sometimes used as a handwash.

    Note: The common bleaching powder is chemically referred to as Calcium hypochlorite and not Sodium hypochlorite.

    Is the chemical safe?

    • Sodium hypochlorite is corrosive and is meant largely to clean hard surfaces.
    • It is not recommended to be used on human beings, certainly not as a spray or shower. Even a 0.05% solution could be very harmful for the eyes.
    • A 1% solution can cause damage to the skin of anyone who comes in contact with it.
    • If it gets inside the body, it can cause serious harm to lungs.

    Does the chemical get rid of the novel coronavirus?

    • The WHO recommends homemade bleach solutions of about 2-10% concentration to clean hard surfaces to clear them of any presence of the novel coronavirus.
    • Cleaning hard surfaces with this solution can disinfect them not just from novel coronavirus but also help prevent flu, food born illnesses, and more.

  • [pib] Indian Institutes of Information Technology (IIIT) Laws (Amendment) Bill, 2020

    Lok Sabha passed the IIIT Laws (Amendment) Bill, 2020.

    About IIIT Act

    • IIITs are envisaged to promote higher education and research in the field of Information Technology.
    • The IIT Act of 2014 and IIIT (Public-Private Partnership) Act, 2017 are the unique initiatives of the govt. to impart knowledge in the field of IT to provide solutions to the challenges faced by the country.
    • Every Institute shall be open to all persons irrespective of gender, caste, creed, disability, domicile, ethnicity and social or economic background.

    What are the proposed Amendments?

    • Introduction of the Amendment 2020 will amend the principal acts of 2014 and 2017.
    • It will grant statutory status to five IIIT in PPP mode in Gujarat (Surat), Madhya Pradesh (Bhopal), Bihar (Bhagalpur), Tripura (Agartala), and Karnataka (Raichur).
    • It would declare them as Institutions of National Importance along with already existing 15 IIIT under the 2017 Act.