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GS Paper: GS3-17.Awareness in the fields of IT, Space, Computers, Robotics, Nano-technology, Bio-technology and issues relating to Intellectual Property Rights.

  • Kuaizhou-11 Rocket

    China’s 19th launch of 2020, the Kuaizhou-11 rocket, failed in its mission.

    Try this question from CSP 2014:

    Q.Which of the following pair is/are correctly matched?

    Spacecraft Purpose
    1. Cassini-Huygens Orbiting the Venus and transmitting data to the Earth
    2. Messenger Mapping and investigating the Mercury
    3. Voyager 1 and 2 Exploring the outer solar system

    Select the correct answer using the code given below.

    a) 1 only

    b) 2 and 3 only

    c) 1 and 3 only

    d) 1, 2 and 3

    The Kuaizhou-11

    • Kuaizhou, meaning “fast ship” in Chinese, was operated by the commercial launch firm Expace and was originally scheduled for 2018 after being developed three years earlier.
    • Also known as KZ-11, it had a lift-off mass of 70.8 tonnes, and was designed to launch low-Earth and Sun-synchronous orbit satellites.
    • It was carrying two satellites — the first being a remote sensing satellite that would provide data to clients on a commercial basis for forecasting and managing geological disasters.
    • It would also provide the information required for natural resource exploration. The second was part of a series of satellites for low-Earth orbit navigation.
    • Both satellites were built by Changguang Satellite Co. Ltd., a commercial entity born out of the state-owned firms.
  • Rare Comet ‘C/2020 F3 Neowise’

    The C/2020 F3 comet also dubbed NEOWISE will be visible with the naked eye for around 20 minutes every day for 20 days across India.

    Try this question from CSP 2014:

    Q.What is a coma, in the content of astronomy?

    (a) Bright half of material on the comet

    (b) Long tail of dust

    (c) Two asteroids orbiting each other

    (d) Two planets orbiting each other

    What are Comets?

    • Comets or “dirty snowballs” are mostly made of dust, rocks and ice, the remnants from the time the solar system was formed over 4.6 billion years ago.
    • The word comet comes from the Latin word “Cometa” which means “long-haired” and the earliest known record of a comet sighting was made by an astrologer in 1059 BC.
    • Comets can range in their width from a few miles to tens of miles wide.
    • While there are millions of comets orbiting the sun, there are more than 3,650 known comets as of now, according to NASA.

    How do they illuminate?

    • Comets do not have the light of their own and what humans are able to see from Earth is the reflection of the sun’s light off the comet as well as the energy released by the gas molecules after it is absorbed from the sun.
    • The visibility cannot be precisely predicted since a lot depends on the way the “outbursts” of gas and dust play out determining how much of a “good show” the comet will put out for observers.
    • As they orbit closer to the sun, they heat up and release debris of dust and gases that form into a “glowing head” that can often be larger than a planet.

    Why do they get close to the sun?

    • Comets may be occasionally pushed into orbits closer to the sun and the Earth’s neighbourhood due to forces of gravity of other planets.
    • The appearance of some comets, like those that take less than 200 years to orbit around the sun is predictable since they have passed by before.
    • These may be referred to as short-period comets and can be found in the Kuiper belt, where many comets orbit the sun in the realm of Pluto, occasionally getting pushed into orbits that bring them closer to the sun.
    • One of the most famous short-period comets is called Halley’s Comet that reappears every 76 years. Halley’s will be sighted next in 2062.
    • Comets in this cloud can take as long as 30 million years to complete one rotation around the sun.

    Significance of the comets

    • NASA tracks all Near Earth Objects (NEOs) that includes comets and asteroids using telescopes placed all around the Earth, as part of its NEO Observation Program.
    • Comets hold important clues about the formation of the solar system and it is possible that comets brought water and other organic compounds, which are the building blocks of life to Earth.

    Back2Basics

  • Carbon enrichment of the Universe

    A recent study has provided new insights on the origins of the carbon in our galaxy.

    Try this question from CSP 2016:

    Q.Consider the following:

    1. Photosynthesis
    2. Respiration
    3. Decay of organic matter
    4. Volcanic action

    Which of the above add carbon dioxide to the carbon cycle on earth?

    (a) 1 and 4 only

    (b) 2 and 3 only

    (c) 2, 3 and 4 only

    (d) 1, 2, 3 and 4

    Why study Carbon?

    • Carbon is essential for life: It is the simple building block of all the complex organic molecules that organisms need.
    • It is known that all the carbon in the Milky Way came from dying stars that ejected the element into their surroundings.
    • What has remained debated, however, is what kind of stars made the major contribution.
    • The study shows the analysis of white dwarfs — the dense remnants of a star after its death.

    How does carbon come from stars?

    • Most stars — except the most massive ones — are doomed to turn into white dwarfs.
    • When the massive ones die, they go with a spectacular bang known as the supernova.
    • Both low-mass and massive stars eject their ashes into the surroundings before they end their lives.
    • And these ashes contain many different chemical elements, including carbon.

    How is it synthesized?

    • Both in low-mass stars and in massive stars carbon is synthesized in their deep and hot interiors through the triple-alpha reaction that is the fusion of three helium nuclei.
    • In low-mass stars, the newly synthesized carbon is transported to the surface [from the interiors] via gigantic bubbles of gas and from there injected into the cosmos through stellar winds.
    • Massive stars enrich the interstellar medium with carbon mostly before the supernova explosion, when they also experience powerful stellar winds.

    Findings of the news research

    • It was earlier debated that whether the carbon in the Milky Way originated from low-mass stars before they became white dwarfs or from the winds of massive stars before they exploded as supernovae.
    • The new research suggests that white dwarfs may shed more light on carbon’s origin in the Milky Way.
    • The researchers measured the masses of the white dwarfs, derived their masses at birth, and from there calculated the “initial-final mass relation”.
    • The IFMR is a key astrophysical measure that integrates information of the entire life cycles of stars.
    • They found that the relationship bucked a trend — that the more massive the star at birth, the more massive the white dwarf left at its death.
    • So far, stars born roughly 1.5 billion years ago in our galaxy were thought to have produced white dwarfs about 60-65% the mass of our Sun.

    What explains this?

    • From an analysis of the initial-final mass relation around the little kink, the researchers drew their conclusions about the size range for the stars that contributed carbon to the Milky Way.
    • Stars more massive than 2 solar masses, too, contributed to the galactic enrichment of carbon.
    • Stars less massive than 1.65 solar masses did not. In other words 1.65-Msun [1.65 times the mass of the Sun] represents the minimum mass for a star to spread its carbon-rich ashes upon death.
  • Who was Herbert Kleber?

    With today’s doodle, Google is remembering Dr Herbert David Kleber, who reframed the field of addiction treatment.

    Try this question from CSP 2016:

    A recent movie titled The Man Who Knew Infinity is based on the biography of-

    (a) S. Ramanujan
    (b) S. Chandrasekhar
    (c) S. N. Bose
    (d) C. V. Raman

    Herbert Kleber

    • Born on June 19, 1934, in Pittsburgh, Pennsylvania, Dr Kleber studied medicine, where he discovered that psychology was his calling.
    • He viewed addiction as a medical condition rather than a moral failure.
    • He spent years treating people with drug addiction and realized that the treatment needed a new approach backed by scientific research.
    • His new methods of treatment gained an appreciation and he was appointed as the deputy director for demand reduction at the Office of National Drug Control Policy by the then U.S. President George H. W. Bush.
    • He headed many projects on developing new methods to treat individuals with alcohol, cocaine, heroin and alcohol addictions.
  • What is Raman Spectroscopy?

    Mumbai-based researchers have turned to Raman Spectroscopy to detect RNA viruses present in saliva samples.

    Try this question from CSP 2017
    Q.Which Indian astrophysicist and Nobel laureate predicted rapidly rotating stars emit polarized light?
    (a) Subrahmanyan Chandrasekhar
    (b) CV Raman
    (c) Ramanujan
    (d) Amartya Sen

    The Raman Spectroscopy

    • Raman spectroscopy is an analytical technique where scattered light is used to measure the vibrational energy modes of a sample.
    • In 1928, Raman discovered that when a stream of light passes through a liquid, a fraction of the light scattered by the liquid is of a different colour.
    • While Raman was returning from London in a 15-day voyage, he started thinking about the colour of the deep blue Mediterranean.
    • He wasn’t convinced by the explanation that the colour of the sea was blue due to the reflection of the sky.
    • As the ship docked in Bombay, he sent a letter to the editor of the journal Nature, in which he penned down his thoughts on this.
      Subsequently, Raman was able to show that the blue colour of the water was due to the scattering of the sunlight by water molecules.
    • By this time he was obsessed with the phenomenon of light scattering.

    How does it work?

    • The Raman Effect is when the change in the energy of the light is affected by the vibrations of the molecule or material under observation, leading to a change in its wavelength.
    • Significantly, it notes that the Raman effect is “very weak” — this is because when the object in question is small (smaller than a few nanometres), the light will pass through it undisturbed.
    • But a few times in a billion, light waves may interact with the particle. This could also explain why it was not discovered before.
    • In general, when light interacts with an object, it can either be reflected, refracted or transmitted.
    • One of the things that scientists look at when light is scattered is if the particle it interacts with is able to change its energy.

    Applications

    • Raman spectroscopy is used in many varied fields – in fact, any application where non-destructive, microscopic, chemical analysis and imaging is required.
    • Whether the goal is qualitative or quantitative data, Raman analysis can provide key information easily and quickly.
    • It can be used to rapidly characterize the chemical composition and structure of a sample, whether solid, liquid, gas, gel, slurry or powder.
  • Decoupling pharmaceutical industry from China should be strategic

    Abrupt ban on import from China would harm the India pharmaceutical industry and disrupt the supply of several essential medicines. Any attempt at reducing the dependence on China for APIs should be strategies, argues the author.

    Dependence of Indian pharma industry on China

    •  India is the third-largest producer of finished drugs in the world.
    • However, India relies significantly on China for supplies of active pharmaceutical ingredients APIs.
    • An estimated 70 per cent of API requirements of India’s pharmaceutical industry are sourced from China.
    • For some drugs, such as paracetamol and ibuprofen, this dependence is almost 100 per cent.
    • This import reliance has been fuelled by environmental controls in India and competition with China, which has higher volumes of production and lower costs.

    Implications of banning import from China

    • Restricting or banning the import of APIs would cause significant disruption to the Indian pharmaceutical industry
    • The pharmaceutical industry had $40 billion in revenues in 2018-19, according to Pharmexcil.
    • Such a prospect is especially of concern to potential patients.
    •  Indian pharmaceutical industry annually exports $20 billion worth of medicine.
    • An ad hoc or reactive decoupling could disrupt the production of a wide range of medicines in India and globally.
    • Such disruption could affect the availability of Dexamethasone and painkillers, such as paracetamol and ibuprofen, as well as antibiotics, such as penicillin.
    • The impacts would be especially high in low and middle-income countries.
    • In many African countries, in fact, India supplies almost 50 per cent of the medicines in value terms.

    Lessons from the past: Policy initiative matters

    • Market share of foreign-owned multinationals in India was 80-90 per cent in 1970 in the pharmaceutical industry.
    • It fell to 50 per cent by the early 1980s, and down to 23 per cent today.
    • The prices of medicines in India fell from being amongst the highest in the world to amongst the lowest.
    • But this did not happen through sudden decoupling from foreign multinationals or a complete boycott or ban on imports.
    •  The 1970 Indian Patent Act removed product patent protection in pharmaceuticals.
    • So, the 1970 Patent Act is widely lauded for facilitating the growth of India’s industry.
    • India also benefited from the 1973 Foreign Exchange Regulation Act (FERA) and the subsequent New Drug Policy (1978).
    • Thus, a series of policy initiatives succeeded in tilting the balance in favour of Indian-owned firms.

    But does it mean we have to depend on China forever?

    • No, but reducing dependence on China will not be easy to achieve.
    • In India, any decoupling from China must be strategic, with significant policy support.
    • It will take time for a paced indigenisation.

    Government moves to reduce dependence for API

    • In March, the government announced Rs 3,000 crore to develop three bulk drug parks.
    • The government also announced Rs 6,940 crore to manufacturers of 53 bulk drugs over the next eight years.
    • Planning ahead towards greater domestic production of APIs, as well as reduced dependence on China, is an understandable and sensible policy objective.
    • Despite a decline in recent decades, India has a stronger starting point than most countries given the continued presence of some API production capabilities.
    • Indian firms have capacities, for instance, to produce COVID-19 treatments, including Remdesivir.

    Consider the question “What are the APIs? Why India depends on other countries for it and what are implications of it? Suggest ways to reduce this dependence.”

    Conclusion

    In the short run, boycotts or bans would be counter-productive for the Indian industry, while also affecting access to much-needed medicines to India’s citizens and beyond. In the long run, however, reducing dependence on China would be strategically prudent.


    Back2Basics: What are APIs?

    • Active pharmaceutical ingredient (API), is the term used to refer to the biologically active component of a drug product (e.g. tablet, capsule).
    • Drug products are usually composed of several components.
    • The API is the primary ingredient.
    • Other ingredients are commonly known as “excipients” and these substances are always required to be biologically safe, often making up a variable fraction of the drug product.
    • The procedure for optimizing and compositing this mixture of components used in the drug is known as “formulation.”
  • Phobos: The closest and biggest moon of Mars

    The Mars Colour Camera (MCC) onboard ISRO’s Mars Orbiter Mission (MOM) has captured the image of Phobos, the closest and biggest moon of Mars.

    Try this question from CSP 2017:

    Q.Which region of Mars has a densely packed river deposit indicating this planet had water 3.5 billion years ago?

    (a) Aeolis Dorsa (b) Tharsis (c) Olympus Mons (d) Hellas

    About Phobos

    • Phobos is the innermost and larger of the two natural satellites of Mars, the other being Deimos.
    • Both moons were discovered in 1877 by American astronomer Asaph Hall.
    • Phobos is a small, irregularly shaped object with a mean radius of 11 km and is seven times as massive as the outer moon, Deimos.
    • Phobos is largely believed to be made up of carbonaceous chondrites.
    • The violent phase that Phobos has encountered is seen in the large section gouged out from a past collision (Stickney crater) and bouncing ejecta.

    Back2Basics: Mars Orbiter Mission (MOM)

    • The MOM also called Mangalyaan is a space probe orbiting Mars since 24 September 2014. It was launched on 5 November 2013 by the Indian Space Research Organisation (ISRO).
    • It aims at studying the Martian surface and mineral composition as well as scans its atmosphere for methane (an indicator of life on Mars).
    • It is India’s first interplanetary mission and it made it the fourth space agency to reach Mars, after Roscosmos, NASA, and the European Space Agency.
    • It made India the first Asian nation to reach Martian orbit and the first nation in the world to do so on its maiden attempt.
    • It was initially meant to last six months, but subsequently, ISRO had said it had enough fuel for it to last “many years.”
  • Gold Nanoparticles and their applications

    Indian researchers have successfully synthesized gold nanoparticles (GNPs) using psychrotolerant Antarctic bacteria through a non-toxic, low-cost, and eco-friendly way.

    Nanotechnology is a pathbreaking technology which can create many new materials and devices with a wide range of applications, such as in nanomedicine, nanoelectronics etc.   GNPs are another distinct development.

    What are Gold Nanoparticles?

    • Metallic NPs have been efficiently exploited for biomedical applications and among them, GNPs are found to be effective in biomedical research.
    • And NPs are those materials that are at least one dimension smaller than 100 nanometers.
    • NPs have a high surface-to-volume ratio and they can provide the tremendous driving force for diffusion, especially at elevated temperatures.
    • GNPs are melted at much lower temperatures (300 °C) than bulk gold (1064 °C).
    • NPs have been found to impart various desirable properties to different day-to-day products.
    • For example, GNPs are found to have greater solar radiation absorbing ability than the conventional bulk gold, which makes them a better candidate for use in the photovoltaic cell manufacturing industry.

    Properties of GNP

    1) Biomedical

    • Genotoxicity describes the property of a chemical agent that is capable of damaging the genetic information of DNA and thus causing the mutation of the cell, which can lead to cancer.
    • The study revealed the genotoxic effect of GNPs on a sulphate reducing bacteria (SRB).
    • These GNPs can be used as composite therapeutic agent clinical trials, especially in anti-cancer, anti-viral, anti-diabetic, and cholesterol-lowering drugs.

    2) Optical

    • GNPs have unique optical properties too. For example, particles above 100 nm show blue or violet colour in the water, while the colour becomes wine red in 100 nm gold colloidal particles.
    • They can thus be used for therapeutic imaging.

    3) Electronics

    • GNPs are also found to be useful in the electronics industry.
    • Scientists have constructed a transistor known as NOMFET (Nanoparticles Organic Memory Field-Effect Transistor) by embedding GNPs in a porous manganese oxide.
    • NOMFETs can mimic the feature of the human synapse known as plasticity or the variation of the speed and strength of the signal going from neuron to neuron.
    • These novel transistors can now facilitate better recreation of certain types of human cognitive processes, such as recognition and image processing and have their application in AI.
  • What is Gynandromorphism?

    Recently, a rare biological phenomenon called Gynandromorphism was observed in dragonflies at Kole wetlands of Kerala.

    Gynandromorphism is a core biology concept. We can expect a prelims question in a rare scenario.

    Try this question from CSP 2013:

    Q.Improper handling and storage of cereal grains and oilseeds result in the production of toxins known as aflatoxins which are not generally destroyed by normal cooking process. Aflatoxins are produced by

    (a) Bacteria (b) Protozoa (c) Moulds (d) Viruses

    Gynandromorphism

    • Gynandromorphs are individual animals that have both genetically male and female tissues and often have observable male and female characteristics.
    • They may be bilateral, appearing to divide down the middle into male and female sides, or they may be mosaic, with patches characteristic of one sex appearing in a body part characteristic of the other sex.
    • Gynandromorphs occur in insects, spiders, crustaceans, and other arthropods as well as in birds, but they are extremely rare, and discovering one in the field or in the laboratory is a major event.
    • Estimating how frequently they occur is difficult because they usually go unnoticed in species where sexual dimorphism is less pronounced.
    • Gynandromorphs have been reported in mosquitoes, fruit flies, and in other insects, but they are most dramatic in those butterfly species in which the male and female wing colours and patterns are dramatically different.
  • Statistics Day and P.C. Mahalanobis

    Statistics Day will be celebrated today on 29th June 2020 to popularize the use of Statistics in everyday life and sensitize the public as to how Statistics helps in shaping and framing policies.

    Try this question from CSP 2016:

    A recent movie titled The Man Who Knew Infinity is based on the biography of-

    (a) S. Ramanujan
    (b) S. Chandrasekhar
    (c) S. N. Bose
    (d) C. V. Raman

    Who was P.C. Mahalanobis?

    • Prasanta Chandra Mahalanobis (29 June 1893 – 28 June 1972) was an Indian scientist and statistician.
    • He is best remembered for the Mahalanobis distance, a statistical measure, and for being one of the members of the first Planning Commission of free India.
    • He made pioneering studies in anthropometry (the science of obtaining systematic measurements of the human body) in India.
    • He founded the Indian Statistical Institute and contributed to the design of large-scale sample surveys.
    • For his contributions, Mahalanobis has been considered the father of modern statistics in India.