Why in the News?
- Renewed focus due to World Health Organization resolution on improving care access and awareness on World Haemophilia Day
What is Haemophilia
- Haemophilia is a genetic bleeding disorder
- Caused by: Deficiency of clotting factors:
- Factor VIII (Haemophilia A)
- Factor IX (Haemophilia B)
Key Characteristics
- Blood does not clot properly
- Leads to:
- Prolonged bleeding
- Internal bleeding (joints, muscles)
- Severe cases:
- Spontaneous bleeding episodes
Causes and Inheritance
- Genetic Nature Inherited as: X-linked recessive disorder
- Affected Population: Mostly males are affected, and Females are carriers.
- Mutation Cases: ~1/3 cases: Occur due to spontaneous mutations
| [2009] In the context of genetic disorders, consider the following: A woman suffers from colour blindness while her husband does not suffer from it. They have a son and a daughter. In this context, which one of the following statements is most probably correct? (a) Both children suffer from colour blindness. (b) Daughter suffers from colour blindness while son does not suffer from it. (c) Both children do not suffer from colour blindness. (d) Son suffers from colour blindness while daughter does not suffer from it. |
