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Health Sector – UHC, National Health Policy, Family Planning, Health Insurance, etc.

Vitamin B12 Deficiency & Skin Manifestations 

Why in the news?

According to a study published in Canad­ian Family Physician, Vitamin B12 deficiency often shows early dermatological symptoms—such as pigmentation, dryness, and inflammation—before neurological or hematological complications appear.

What is Vitamin B12?

  • Water-soluble vitamins are essential for: Red blood cell formation, Nerve function, DNA synthesis and Cell growth and repair

Why Skin Shows Early Signs?

  • B12 deficiency → reduced RBC production → low oxygen delivery to skin → visible skin changes.
  • Weak immunity and impaired nerve function further worsen dermatological issues.
High-Risk Groups

More prone to Vitamin B12 deficiency:

  • Vegetarians/vegans
  • Adults > 50 years
  • Individuals with:
    • Gastritis, Crohn’s disease, celiac disease
  • Those taking:
    • Antacids (PPIs/H2 blockers)
    • Metformin
  • People with poor nutrient absorption
Consider the following pairs: Vitamin : Deficiency disease (2014)

1. Vitamin C : Scurvy 

2. Vitamin D : Rickets 

3. Vitamin E : Night Blindness 

Which of the pairs given above is/are correctly matched? 

(a) 1 and 2 only (b) 3 only (c) 1, 2 and 3 only (d) None

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