Innovations in Biotechnology and Medical Sciences

What is Darwin Tree of Life (DToL) Project?

Why in the News?

Researchers in Britain & Ireland are aiming to sequence all animals, fungi and plants under the Darwin Tree of Life (DToL) Project.

About Darwin Tree of Life (DToL) Project:

  • Objective: To sequence the genomes of all ~70,000 known eukaryotic species (whose cells contain a nucleus and other membrane-bound organelles) found in Britain and Ireland.
  • Initiated: In 2019 as a UK–Ireland contribution to the Earth BioGenome Project.
  • Geographic Focus: Great Britain and Ireland, chosen for their well-documented and accessible biodiversity.

Key Features:

  • Phases:
    • Pilot Phase (2019–2022): Focused on collecting 8,000 species; targeted 2,000 genome assemblies.
    • As of 2025: ~8,000 species collected; over 2,000 genomes sequenced.
  • Approach:
    • Systematic specimen collection and species verification.
    • High-quality genome sequencing using advanced tools and curated pipelines.
  • Public Access: All genome data is released openly via the DToL portal and public archives.
  • Scientific Significance:
    • Enhances understanding of evolution, adaptation, and species relationships.
    • Supports conservation efforts amid growing biodiversity threats.
  • Applications: Informs conservation biology, medicine, agriculture, and climate adaptation.
[UPSC 2011] At present, scientists can determine the arrangement or relative positions of genes or DNA sequences on a chromosome. How does this knowledge benefit us?

1. It is possible to know the pedigree of livestock.

2. It is possible to understand the causes of all human diseases.

3. It is possible to develop disease-resistant animal breeds.

Options: (a) 1 and 2 only (b) 2 only (c) 1 and 3 only* (d) 1, 2 and 3

 

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