With reference to monoclonal antibodies, consider the following

With reference to monoclonal antibodies, consider the following:
I. They are man-made proteins.
II. They stimulate the patient’s immune system to fight the specific disease.
III. They are produced using animal cells only.
Which of the statements given above are correct?

(a)

I and II only

(b)

II and III only

(c)

I and III only

(d)

All the three

Answer:

(d)

Moderate

Application Based

Core Books/NCERT

Explanation

Statement I is correct: They are man-made proteins • Correct. Monoclonal antibodies are laboratory-produced molecules engineered to serve as substitute antibodies that can restore, enhance, or mimic the immune system’s attack on cells. 2. Statement II is correct: They stimulate immunological function due to their ability to bind to specific antigens • Correct. Monoclonal antibodies are designed to bind to specific antigens, such as those found on cancer cells or viruses, thereby triggering an immune response. 3. Statement III is correct: They are used in treating viral infections like that of Nipah virus • Correct. Monoclonal antibodies have been explored and used in the treatment of viral infections, including Ebola and Nipah virus. For instance, monoclonal antibodies like m102.4 have shown potential against Nipah virus in experimental settings. Therefore, all three statements are correct: (d) I, II and III.