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Subject: Science and Technology

  • Community Cord Blood Banking

    Community Cord Blood Banking, a stem cell banking initiative, has recently helped save the life of a girl child making it India’s first dual cord blood transplant through an unrelated donor.

    Must read:

    What is Cord Blood Banking?

    • Community Banking is a new sharing economy model of stem cell banking that was pioneered by LifeCell in India.
    • Parents who choose to store their child’s cord blood in a community bank will have access, in the event of medical need, to all of the other cord blood units in the bank.
    • A community bank is like a public cord blood bank in that the members are supporting each other, but it is also like a private bank because the members pay for this service and outsiders cannot participate.
    • It can fill an unmet health need in a country like India, where there is no national network of public banks and the population has unique genetics that are not covered by banks elsewhere in the world.
    • It is different from “hybrid” banking where both public and family banks share a laboratory, because in hybrid banks the pubic and family sides operate separately.
    • In a community bank the public and family functions are blended.

    Benefits of cord blood

    • It gives protection to a baby against all conditions treatable using stem cells (own & donor).
    • It gives protection to the baby’s siblings, parents and grandparents (maternal & paternal) by providing unrelated donor stem cells.

    Back2Basics: Stem Cell Therapy

    • It is a type of treatment option that uses a patient’s own stem cells to repair damaged tissue and repair injuries.
    • It is used to treat more than 80 disorders including neuromuscular and degenerative disorders. Eg. Bone-marrow transplant is used in Leukemia (blood cancer), sickle-cell anemia, immunodeficiency disorders.
    • Stem cells are usually taken from one of the two areas in the patient’s body: bone marrow or adipose (fat) tissue in their upper thigh/abdomen.
    • Because it is common to remove stem cells from areas of stored body fat, some refer to stem cell therapy as “Adipose Stem Cell Therapy” in some cases.
  • Needed, a policy framework in step with technology

    The changing realm of technology requires a change in the policy framework. The article discusses the issue of the impact of technology and the required changes in the policy framework.

    Adoption of information-based technologies

    • The expansion of computing power has driven the pace of information gathering and analysis.
    • The new currency drives processes and decision-making across a wide array of products and services, making them more efficient and value accretive for consumers.
    • These information-based technologies have been widely adopted across a broad range of industries and products that traditionally have not been perceived as electronic or software based.
    •  A modern automobile has 40% of its component value from electronic-based products.
    • This is a paradigm shift as the amount of “value add” from intangible technology services as opposed to physical objects, even in traditional goods, is being transformed by information.
    • Information and electronics are becoming all-pervasive, ensuring that we set boundaries to control quality or the uptime of the equipment.
    • Information availability drives efficiency and creates value for customers by providing greater control over the product
    • There is increasing digitisation and electronification of industrial activities, products and services, influencing the evolving skill sets in industry.

    Need for holistic views in policies

    • To address the needs of various stakeholders, governments have tended to build specialised departments and designed policies that govern those areas.
    • Over time, as each of these departments grew, they have tended to operate in silos.
    • The recent developments in technology have, however, blurred standard boundaries that dictate policy framework in most governments.
    • As technology is driving an increasing share of the value add coming from digitisation and data analytics, there needs to be a way of encouraging capital formation by way of intangibles in traditionally tangible industries.
    • There is a need to have a holistic view of policies for economic development as technology is becoming a significant enabler in most industries.
    • A change in policy framework regarding economic development that enables various ministries to work together is essential.

    Way forward

    • A nourishing ecosystem for industry, including the hard infrastructure and softer areas such as education, skilling, technical institutions, laboratories, testing centres, etc., has to be cultivated.
    • The creation of clusters of companies in adjacent but complementary areas could constitute such an ecosystem that encourages multi and cross-disciplinary learning and spur innovation and economic development.
    • Moreover, this type of ecosphere could also attract investment and capital formation.
    • There is also the larger issue of a shift of value between manufacturing and services as technology changes.
    • The policy, by and large, promotes and gives incentives for manufacturing, whereas the share of intangibles are not adequately covered in industrial policies.
    • It is important to include these to encourage innovation and technological development.
    • It is important that there is close cooperation and alignment between the Centre and State to ensure effective implementation on the ground.

    Conclusion

    Some of these thoughts could help us navigate through an ecosystem that is changing with technology.

  • What is mRNA vaccine?

    The Moderna and Pfizer vaccines which recently announced their success use the same technology, based on messenger RNA, or mRNA.

    Try this PYQ first:

    Q.‘RNA interference (RNAi)’ technology has gained popularity in the last few years. Why?

    1. It is used in developing gene silencing therapies.
    2. It can be used in developing therapies for the treatment of cancer.
    3. It can be used to develop hormone replacement therapies.
    4. It can be used to produce crop plants that are resistant to viral pathogens.

    Select the correct answer using the code given below:

    (a) 1, 2 and 4

    (b) 2 and 3

    (c) 1 and 3

    (d) 1 and 4 only

    What is mRNA?

    • Messenger RNA (mRNA) is a single-stranded RNA (Ribo Nucleic Acid) molecule that is complementary to one of the DNA strands of a gene.
    • The mRNA is an RNA version of the gene that leaves the cell nucleus and moves to the cytoplasm where proteins are made.
    • During protein synthesis, an organelle called a ribosome moves along the mRNA, reads its base sequence, and uses the genetic code to translate each three-base triplet, or codon, into its corresponding amino acid.

    What is the mRNA vaccine?

    • Such vaccines make use of the messenger RNA molecules that tell the body’s cells what proteins to build.
    • The mRNA, in this case, is coded to tell the cells to recreate the spike protein of the coronavirus SARS-CoV-2, which causes Covid-19.
    • It is the spike protein — which appears as spikes on the surface of the coronavirus — that initiates the process of infection; it allows the virus to penetrate cells, after which it goes on to replicate.
    • A coronavirus vaccine based on mRNA, once injected into the body, will instruct the body’s cells to create copies of the spike protein.
    • In turn, this is expected to prompt the immune cells to create antibodies to fight it.
    • These antibodies will remain in the blood and fight the real virus if and when it infects the human body.

    Back2Basics: Ribo Nucleic Acid (RNA)

    • RNA is an important biological macromolecule that is present in all biological cells.
    • It is principally involved in the synthesis of proteins, carrying the messenger instructions from DNA, which itself contains the genetic instructions required for the development and maintenance of life.
    • In some viruses, RNA, rather than DNA, carries genetic information.
    • The type of RNA dictates the function that this molecule will have within the cell.
    • Aside from the coding region of messenger RNA (mRNA) molecules that will be translated into proteins, other cellular RNA elements are involved in different processes.
  • Leonid Meteor Shower

    The Leonid meteor showers are currently making their yearly appearance and will reach their peak in India on November 17 and 18.  In August this year, there was another meteor called Perseids Shower.

    Try this question from CSP 2014:

    Q.What is a coma, in the content of astronomy?

    (a) Bright half of material on the comet

    (b) Long tail of dust

    (c) Two asteroids orbiting each other

    (d) Two planets orbiting each other

    What is Leonid Meteor Shower?

    • Meteor showers are named after the constellation they appear to be coming from.
    • The Leonids originate from the constellation Leo the Lion– the groups of stars which form a lion’s mane.
    • They emerge from the comet Tempel-Tuttle, which requires 33 years to revolve once around the Sun.
    • These meteors are bright and among the fastest moving– travelling at speeds of 71 km per second.
    • During this year’s showers, peaks of around 10 to 15 meteors are expected to be seen every hour.
    • The Leonid showers include fireballs– bright and large meteors than can last longer than average meteors, and “earthgazers”– meteors which appear close to the horizon with colourful and long tails.

    What is a meteor shower?

    • On its journey around the Sun, the Earth passes through large swathes of cosmic debris.
    • The debris is essentially the remnants of comets — great frigid chunks of matter that leave behind dirty trails of rocks and ice that linger long after the comets themselves have passed.
    • As the Earth wades through this cloud of comet waste, the bits of debris create what appears from the ground to be a fireworks display in the sky — known as a meteor shower.
    • Several meteor showers can be seen around the year. According to NASA, over 30 meteor showers occur annually and are observable from the Earth.

    Back2Basics:

  • SpaceX-NASA’s Crew-1 Mission

    SpaceX’s Crew Dragon spacecraft will lift off carrying a crew of four people to the International Space Station (ISS) on a six-month-long mission.

    What is the Crew-1 Mission?

    • The mission is part of NASA’s Commercial Crew Program, whose objective is to make access to space easier in terms of its cost.
    • This will carry four astronauts on NASA missions, maintaining a space station crew of seven to maximize time dedicated to scientific research on the orbiting laboratory.
    • With this, the cargo and crew can be easily transported to and from the ISS, enabling greater scientific research.
    • At the ISS, the crew will join the members of Expedition 64, the space station crew currently in residence at the ISS.

    Mission goals

    • The goals of the mission are the same as that of Expedition 1 that lifted off 20 years ago.
    • NASA has called both of these ISS missions “historic”.
    • At the ISS, the Crew-1 team will join members of Expedition 64 and conduct microgravity studies and deliver new science hardware to ISS.
    • Once in orbit, NASA astronauts will collect samples to provide data to scientists back on Earth so that they can continue to study how dietary changes affect his body.
    • The crew will also study the effects of dietary improvements on immune function and the gut microbiome and how those improvements can help crews adapt to spaceflight.

    The term micro-g environment is more or less synonymous with the terms weightlessness and zero-g, but with an emphasis on the fact that g-forces are never exactly zero—just very small.

  • Thirty Metre Telescope (TMT)

    With regime change in the US, hopes have been raised for the Thirty Meter Telescope (TMT) in Hawaii. India is one of the partners in the ambitious next-generation observatory project along with the US, Canada, China and Japan.

    Try this PYQ:

    Q.“Event Horizon” is related to:

    (a) Telescope

    (b) Black hole

    (c) Solar glares

    (d) None of the above

    Thirty Metre Telescope

    • The TMT is a proposed astronomical observatory with an extremely large telescope (ELT) that has become the source of controversy over its planned location on Mauna Kea on the island of Hawaii.
    • It is being built by an international collaboration of government organisations and educational institutions, at a cost of $1.4 billion.
    • “Thirty Metre” refers to the 30-metre diameter of the mirror, with 492 segments of glass pieced together, which makes it three times as wide as the world’s largest existing visible-light telescope.
    • The larger the mirror, the more light a telescope can collect, which means, in turn, that it can “see” farther, fainter objects.
    • It would be more than 200 times more sensitive than current telescopes and would be able to resolve objects 12 times better than the Hubble Space Telescope.

    Utility of the telescope

    • One of its key uses will be the study of exoplanets, many of which have been detected in the last few years, and whether their atmospheres contain water vapour or methane — the signatures of possible life.
    • For the first time in history, this telescope will be capable of detecting extraterrestrial life.
    • The study of black holes is another objective.
    • While these have been observed in detail within the Milky Way, the next galaxy is 100 times farther away; the Thirty Metre Telescope will help bring them closer.
  • GRACE-FO Mission

    The GRACE-FO mission has mapped deviation in Earth’s surface mass and spatial variations in the rate of sea-level rise between 1993 and 2018 using altimetric and gravimetric analysis.

    Try this MCQ:

    Q.NASA’s VIPER mission sometimes seen in news is related to the study of-

    a)Moon

    b)Venus

    c)Sun

    d)None of these

    GRACE-FO Mission

    • The Gravity Recovery and Climate Experiment Follow-On (GRACE-FO) mission launched in 2018 is a partnership between NASA and the German Research Centre for Geosciences (GFZ).
    • It is a successor to the original GRACE mission, which orbited Earth from 2002-2017.
    • It carries on the extremely successful work of its predecessor while testing a new technology designed to dramatically improve the already remarkable precision of its measurement system.

    How did NASA measure this?

    (1) Altimetric Study

    • Altimetry missions are used to know the ocean surface topography — the shape and height of the ocean’s peaks and valleys.
    • Radar altimeters continually send out pulses of radio waves (microwaves) that bounce off the surface of the ocean and reflect back toward the satellite.
    • The instrument calculates the time it takes for the signal to return, while also tracking the precise location of the satellite in space. From this, scientists can derive the height of the sea surface directly underneath the satellite.

    (2) Gravimetric Study

    • Gravimetry is a process of using ice’s gravitational pull on a pair of satellites. It helps estimate ice loss and its contribution to sea-level rise.
    • The twin satellites in each mission detect subtle shifts in Earth’s gravity field.
    • The strength of gravitational forces is determined by mass, so changes in Earth’s gravity field indicate a change or redistribution in mass.
  • What is Einstein’s Eclipse?

    This newscard is an excerpt from the original article published in the DownToEarth.

    Einstein’s Eclipse

    • Albert Einstein’s prediction of the bending of light by the gravity of the Sun, one of the components of his general theory of relativity, can be tested during a solar eclipse.
    • Following an unsuccessful attempt to validate this prediction during the Solar eclipse of June 8, 1918, two expeditions were made to measure positions of stars during this eclipse.
    • The eclipse presented a rare chance to verify one of the essential consequences of general relativity, the bending of light by gravity.
    • Einstein’s theory predicted that rays of light passing near a massive body in space would be visibly bent as they followed the curve in space-time created by the body’s mass.
    • In the case of a ray of light originating from a distant star and passing near the edge of the Sun, Einstein calculated a deflection of about 1.75 arc seconds.

    Try this PYQ:

    Q.Consider the following phenomena:

    1. Light is affected by gravity.
    2. The Universe is constantly expanding.
    3. Matter warps its surrounding space-time.

    Which of the above is/are the predictions of Albert Einstein’s General Theory of Relativity, often discussed in media?

    (a) 1 and 2 only

    (b) 3 only

    (c) 1 and 3 only

    (d) 1, 2 and 3

    What was studied during the eclipse?

    • Einstein published his theory and predictions in 1915, and in 1919 the British physicist Sir Arthur Eddington took advantage of a total solar eclipse to attempt to detect the shifting images of stars near the limb of the sun.
    • The problem was that during totality the sky does not get perfectly dark, and only a handful of stars were visible near the sun from which to make the measurement.
    • The darkness of an eclipse, though, would allow the astronomers to observe and photograph the field of stars around the Sun.
    • By comparing the photographs with reference images taken at night, it would be possible to measure how much the presence of the Sun had bent the stars’ light.
    • Conveniently, a cluster of bright stars known as the Hyades would appear near the Sun during the eclipse.

    Significance

    • After several months of analysis, researchers announced in November that their findings supported the theory of general relativity.
    • Media coverage tended to dwell on the recondite nature of Einstein’s work, emphasizing that there were only a handful of people in the world who could understand it.
    • It could be argued that 1919 was the year when Einstein’s name became a byword for superhuman intellectual ability—making possible the small industry of Einstein-themed merchandise that still exists today.

    Back2Basics: General Relativity

    • Einstein’s theory proposes that gravity is not an actual force, but is instead a geometric distortion of space-time not predicted by ordinary Newtonian physics.
    • The more mass you have to produce the gravity in a body, the more distortion you get.
    • This distortion changes the trajectories of objects moving through space, and even the paths of light rays, as they pass close-by the massive body.
    • Even so, this effect is very feeble for an object as massive as our own sun, so it takes enormous care to even detect that it is occurring.
    • General Relativity predicts how much of this bending of light you should see given the mass of the object.
    • Called ‘gravitational lensing’ it has been detected on the cosmological scale as entire clusters of galaxies distort the light from more distant galaxies behind them as this image from the Hubble Space Telescope shows.
  • What is a Fast Radio Burst (FRB)?

    NASA has reported that it observed a mix of X-ray and radio signals never observed before in the Milky Way.

    Such news makes us think about alien and extraterrestrial life at the first. Do not get carried away with such thoughts. Its simply a space based phenomena.

    What is an FRB?

    • The first FRB was discovered in 2007, since when scientists have been working towards finding the source of their origin.
    • Essentially, FRBs are bright bursts of radio waves (radio waves can be produced by astronomical objects with changing magnetic fields).
    • Its durations lie in the millisecond-scale, because of which it is difficult to detect them and determine their position in the sky.

    Who discovered it?

    • The X-ray portion of the simultaneous bursts was detected by several satellites, including NASA’s Wind mission.
    • Further, a NASA-funded project called Survey for Transient Astronomical Radio Emission 2 (STARE2) also detected the radio burst.

    Why are they significant?

    • First noticed in 2018 by the Canadian observatory the waves have created ripples across the globe for one reason — they arrive in a pattern.
    • This gave birth to theories that they could be from an alien civilization.
    • Initially, it was believed that the collision of black holes or neutron stars triggers them.
    • But the discovery of repeating FRBs debunked the theory of colliding objects.

    What is the origin of the FRB detected in April?

    • The source of the FRB detected in April in the Milky Way is a very powerful magnetic neutron star, referred to as a magnetar.
    • Magnetar is located in the constellation Vulpecula and is estimated to be between 14,000-41,000 light-years away.
    • The FRB was part of one of the magnetar’s most prolific flare-ups, with the X-ray bursts lasting less than a second.

    What is a magnetar?

    • A magnetar is a neutron star, “the crushed, city-size remains of a star many times more massive than our Sun.”
    • The magnetic field of such a star is very powerful, which can be over 10 trillion times stronger than a refrigerator magnet and up to a thousand times stronger than typical neutron stars.
    • Neutron stars are formed when the core of a massive star undergoes gravitational collapse when it reaches the end of its life.
  • Kawasaki Disease

    Children in the world over have shown to be affected by either Kawasaki Disease (KD) since the reopening of schools.

    Try this PYQ:

    Q.H1N1 virus is sometimes mentioned in the news with reference to which one of the following diseases?

    (a) AIDS

    (b) Bird flu

    (c) Dengue

    (d) Swine flu

    What is Kawasaki Disease?

    • Kawasaki disease is an illness that causes blood vessels to become inflamed, almost always in young children.
    • Its cause is yet unknown. It is one of the leading causes of heart disease in kids.
    • But doctors can treat it if they find it early. Most children recover without any problems.

    Symptoms

    Kawasaki disease comes on fast, and symptoms show up in phases. Signs of the first phase of Kawasaki disease include:

    • High fever that lasts more than 5 days
    • Swelling and redness in hands and bottoms of feet
    • Red eyes
    • Swollen glands, especially in the neck
    • Irritated throat, mouth, and lips

    In the second phase, symptoms include:

    • Joint pain
    • Stomach trouble, such as diarrhoea and vomiting
    • Peeling skin on hands and feet