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Type: Prelims Only

  • Human Outer Planet Exploration (HOPE)

    Why in the News?

    India has taken a significant step towards interplanetary human missions with the launch of the Human Outer Planet Exploration (HOPE) analogue station at Tso Kar, Ladakh.

    hope

    About HOPE (Human Outer Planet Exploration):

    • Purpose: Simulates Moon and Mars conditions to prepare for future human missions.
    • Developer: Built by Protoplanet (Bengaluru); partially funded by ISRO.
    • Location: Tso Kar, Ladakh (14,500 ft) — chosen for its lunar/Martian-like terrain.
    • Features: Enables isolation research, tech trials, and crew training; 1 of 33 such stations globally.
    • First Mission (2025): Two scientists (Rahul Mogalapalli, Yaman Akot) conducted a 10-day simulation focusing on resilience and mental health.
    • Significance:
      • Boosts India’s human spaceflight readiness.
      • Supports goals like Bharatiya Antariksh Station (2035) and Moon mission (2040).

    India’s Astronomical Assets in Ladakh:

    • Location: Indian Astronomical Observatory (IAO), at Mt. Saraswati (4,500 m), Hanle; run by Indian Institute of Astrophysics.
    • Key Instruments:
      • Himalayan Chandra Telescope (optical/infrared)
      • HAGAR (gamma rays, with Tata Institute of Fundamental Research)
      • MACE (Cherenkov telescope, with Bhabha Atomic Research Centre)
    • Stargazing hubs: Hanle, Nubra Valley, Pangong, Tso Moriri.
    • Advantages & Recognition:
      • 270+ clear nights; low humidity; dark skies.
      • Declared India’s 1st Dark-Sky Reserve (2022) to curb light pollution.
    [UPSC 2012] The world’s highest ground based telescopic observatory is located in

    Options: (a) Colombia (b) India* (c) Nepal (d) Switzerland

     

  • Biologics & Biosimilars: The next frontier in Affordable Medicines

    Why in the News?

    While most medicines are small molecule drugs with simple structures, a newer class—biologics and biosimilars—is reshaping modern medicine with their complex, targeted action.

    What are Small Molecule Drugs?

    • Definition: Chemically synthesised, low molecular weight compounds.
    • Features: Fixed structure, chemically stable, easy to replicate, patent-protected.
    • Cost Dynamics: Expensive while under patent; affordable generics post-expiry (e.g., Sovaldi dropped from $84,000 to $1,000).

    About Biologics & Biosimilars:

    • Biologics-
      • Overview: Large, complex drugs made from living cells or organisms.
      • Examples: Insulin (~5,800 daltons), Remicade (~150,000 daltons).
      • Nature: Slight structural variations possible; used for cancer, autoimmune diseases, hormone therapy.
    • Biosimilars-
      • Overview: Near-identical versions of biologics, made after patent expiry.
      • Not Generics: Due to complex cell-based production, they’re similar but not identical.
      • Use: Offer lower-cost alternatives to high-end biologics.

    Regulation and Reform:

    • Current Barriers: Biosimilars need costly trials (animal + clinical), unlike generics.
    • Global Moves: UK and USA are easing animal trial norms (organ-on-chip, human models).
    • India: Still follows older norms; waivers under review, but clinical trials still mandatory.

    Significance for India:

    • Access: Generic small molecules transformed Indian healthcare.
    • Opportunity: Affordable biosimilars can do the same for chronic and rare diseases.
    • Urgency: Regulatory reform is key to reduce costs, speed up access, and widen healthcare coverage.
    [UPSC 2020] What is the importance of using Pneumococcal Conjugate Vaccines in India?

    (1) These vaccines are effective against pneumonia as well as meningitis and sepsis. (2) Dependence on antibiotics that are not effective against drug-resistant bacteria can be reduced. (3) These vaccines have no side effects and cause no allergic reactions.

    Options: (a) 1 only (b) 1 and 2 only* (c) 1 and 3 only (d) 1, 2 and 3

     

  • 71st National Film Awards announced

    Why in the News?

    The Ministry of Information and Broadcasting has announced the 71st National Film Awards.

    About National Film Awards:

    • Establishment: Instituted in 1954, administered by the Directorate of Film Festivals (DoFF) under the Ministry of Information and Broadcasting, Government of India.
    • Purpose:
      • To encourage the production of films of aesthetic and technical excellence.
      • Promote films that reflect the cultural and social fabric of India.
      • Recognize and reward cinematic achievements across languages and formats.
    • Award Components:
      • Swarna Kamal (Golden Lotus): Includes medallion, certificate, and cash prize. Given in top categories.
      • Rajat Kamal (Silver Lotus): Awarded in various other categories.
    • Main Categories:
      • Feature Films: For artistic and technical excellence across Indian languages.
      • Non-Feature Films: For documentaries, shorts, and socially relevant content.
      • Best Writing on Cinema: For books and critics advancing understanding of cinema.
    • Eligibility Criteria:
      • Films must be produced in India.
      • Makers must be Indian nationals.
      • Must be certified by CBFC between Jan 1 and Dec 31.
      • Foreign co-productions have specific eligibility conditions.
    • Jury and Selection:
      • Independent juries for each category.
      • No governmental or commercial influence in the selection process.

    About Dadasaheb Phalke Award:

    • Part of NFA.
    • India’s highest cinematic honour.
    • Instituted in 1969 to commemorate Dhundiraj Govind Phalke, India’s first filmmaker.
    • Consists of:
      • Swarna Kamal
      • ₹10 lakh cash prize
      • Certificate, silk roll, and shawl
    • First recipient: Devika Rani Roerich

     

  • Age Cap for Surrogacy in India

    Why in the News?

    The Supreme Court of India has reserved its judgment (i.e. final decision is pending) in a set of petitions challenging the age-related eligibility criteria under the Surrogacy (Regulation) Act, 2021.

    These cases involve couples who had initiated the surrogacy process prior to the enactment of the law on January 25, 2022, but are now disqualified due to the new age limits.

    About the Surrogacy (Regulation) Act, 2021

    • Objective: To regulate surrogacy in India, prohibit commercial surrogacy, and promote ethical, altruistic surrogacy based on medical necessity.
    • Scope:

    Key Provisions:

    • Type Permitted: Only altruistic surrogacy (unpaid surrogate mother) is allowed; commercial surrogacy is banned.
    • Eligibility Criteria for Intending Couples:
      • Legally married for at least 5 years.
      • Woman must be 23–50 years of age; man must be 26–55 years.
      • Must not have any living biological, adopted, or surrogate child.
    • Eligibility for Single Women:
      • Only widows or divorcees between 35–45 years are eligible.
      • Unmarried women are not eligible (currently under challenge).
    • Surrogate Mother Criteria:
      • Must be a close relative, married, and have at least one biological child.
      • Age: 25–35 years.
    • Certification Requirement: A Certificate of Essentiality is required, including:
      • Proof of infertility
      • Court order for parentage and custody
      • Insurance for the surrogate mother
    • Penalties: Commercial surrogacy invites imprisonment (up to 10 years) and fines (up to ₹10 lakh).
    • Regulatory Structure:
      • National Surrogacy Board at the central level.
      • State Surrogacy Boards at the state level.

    Issues Highlighted by the Supreme Court:

    • No Transitional Provision: The Act lacks a grandfather clause to protect couples who began the surrogacy process (e.g., embryo freezing) before the law came into effect in January 2022.
    • Rigid Age Limits: The court questioned the fairness of disqualifying couples solely on age grounds, especially when natural pregnancies at older ages are not prohibited.
    • Violation of Fundamental Rights: Petitioners argued the age restrictions violate Article 14 (equality before law) and Article 21 (right to reproductive autonomy and personal liberty).
    • Exclusion of Unmarried Women: The law permits only widows or divorcees (35–45 years) to pursue surrogacy, which the court noted may be arbitrary and discriminatory.
    • Law’s Intent vs. Impact: The court stressed that while the law aims to prevent commercial surrogacy, it should not unreasonably prevent genuine intending parents from having children.
    [UPSC 2020] In the context of recent advances in human reproductive technology, “Pronuclear Transfer” is used for:

    Options: (a) fertilization of egg in vitro by the donor sperm (b) genetic modification of sperm producing cells (c) development of stem cells into functional embryos (d) prevention of mitochondrial diseases in offspring*

     

  • What is Darwin Tree of Life (DToL) Project?

    Why in the News?

    Researchers in Britain & Ireland are aiming to sequence all animals, fungi and plants under the Darwin Tree of Life (DToL) Project.

    About Darwin Tree of Life (DToL) Project:

    • Objective: To sequence the genomes of all ~70,000 known eukaryotic species (whose cells contain a nucleus and other membrane-bound organelles) found in Britain and Ireland.
    • Initiated: In 2019 as a UK–Ireland contribution to the Earth BioGenome Project.
    • Geographic Focus: Great Britain and Ireland, chosen for their well-documented and accessible biodiversity.

    Key Features:

    • Phases:
      • Pilot Phase (2019–2022): Focused on collecting 8,000 species; targeted 2,000 genome assemblies.
      • As of 2025: ~8,000 species collected; over 2,000 genomes sequenced.
    • Approach:
      • Systematic specimen collection and species verification.
      • High-quality genome sequencing using advanced tools and curated pipelines.
    • Public Access: All genome data is released openly via the DToL portal and public archives.
    • Scientific Significance:
      • Enhances understanding of evolution, adaptation, and species relationships.
      • Supports conservation efforts amid growing biodiversity threats.
    • Applications: Informs conservation biology, medicine, agriculture, and climate adaptation.
    [UPSC 2011] At present, scientists can determine the arrangement or relative positions of genes or DNA sequences on a chromosome. How does this knowledge benefit us?

    1. It is possible to know the pedigree of livestock.

    2. It is possible to understand the causes of all human diseases.

    3. It is possible to develop disease-resistant animal breeds.

    Options: (a) 1 and 2 only (b) 2 only (c) 1 and 3 only* (d) 1, 2 and 3

     

  • Patalpani-Kalakund Heritage Railway

    Why in the News?

    The 155-year-old Patalpani–Kalakund heritage train services has resumed after a temporary halt.

    About the Patalpani–Kalakund Heritage Line:

    • Route: 9.5 km metre-gauge section between Patalpani and Kalakund in Madhya Pradesh.
    • Section: Part of the Dr. Ambedkar Nagar (Mhow)–Khandwa route.
    • Restoration Year: Revived in 2018 as a heritage line after being excluded from gauge conversion due to difficult terrain.
    • Operational Details:
      • Average speed: 5–10 km/h.
      • Features scenic gorges, tunnels, embankments, Patalpani waterfall, and natural springs.
    • Historical Origins:
      • Proposed by Maharaja Tukoji Rao Holkar II in 1870.
      • First constructed as part of Holkar State Railways, completed in 1878.
      • Became part of Rajputana–Malwa Railway in 1881–82.
    • Cultural Significance:
      • Patalpani station named after Tantia Bhil, a tribal revolutionary.
      • Kalakund station named after a local sweet delicacy.

    Other Heritage Railways of India:

    Name & Route Details
    Darjeeling Himalayan Railway
    • Location: West Bengal
    • UNESCO Status: World Heritage Site (1999)
    • Built: 1879–81
    • Highlights: Batasia Loop, zigzags, colonial-era steam engines
    • Route: New Jalpaiguri to Darjeeling (88 km, narrow gauge)
    Nilgiri Mountain Railway
    • Location: Tamil Nadu
    • UNESCO Status: World Heritage Site (2005)
    • Highlights: Only rack-and-pinion railway in India, steep climbs, vintage locomotives
    • Route: Mettupalayam to Ooty (46 km, metre gauge)
    Kalka–Shimla Railway
    • Location: Himachal Pradesh
    • UNESCO Status: World Heritage Site (2008)
    • Built: 1898–1903
    • Highlights: 102 tunnels, 800+ bridges; access to British summer capital
    • Route: Kalka to Shimla (96 km, narrow gauge)
    Matheran Hill Railway
    • Location: Maharashtra
    • UNESCO Status: Tentative World Heritage Site
    • Built: 1907
    • Highlights: Zigzags, tight curves, eco-sensitive, vehicle-free destination
    • Route: Neral to Matheran (21 km, narrow gauge)
    Kangra Valley Railway
    • Location: Himachal Pradesh
    • UNESCO Status: Tentative World Heritage Site
    • Highlights: 971 bridges, 2 tunnels; scenic Dhauladhar views, access to ancient temples
    • Route: Pathankot to Joginder Nagar (163 km, narrow gauge)

     

    [UPSC 2009] Recently, which one of the following was included in the UNESCO’s World Heritage list?

    Options: (a) Dilwara Temple (b) Kalka-Shimla Railway* (c) Bhiterkanika Mangrove Area (d) Vishakhapatnam to Araku Valley railway line

     

  • Piprahwa Relics of Buddha

    Why in the News?

    The Union Culture Ministry has successfully retrieved the sacred ‘Piprahwa’ Buddhist relics, which were set to be auctioned in Hong Kong.

    Piprahwa Relics of Buddha

    About the Piprahwa Relics:

    • Discovery: Unearthed in 1898 by William Claxton Peppe, a British engineer, at Piprahwa (Siddharthnagar, Uttar Pradesh), near the Nepal border.

    • Historical Significance: Identified as ancient Kapilavastu, capital of the Shakya republic, where Prince Siddhartha (Buddha) lived before renunciation.

    • Findings at the Site: A buried stupa yielded a large stone coffer containing:

      • Bone fragments believed to be Buddha’s relics
      • Caskets made of soapstone and crystal
      • A sandstone coffer
      • Over 1,800 ornaments: pearls, rubies, sapphires, gold sheets

    • Legal Custody:

      • The British Crown claimed the relics under the Indian Treasure Trove Act, 1878.
      • Most artifacts were transferred to the Indian Museum, Kolkata.

    Stupas with Buddha’s Relics:

    • After the Buddha’s death (Mahaparinirvana), his cremated relics were divided among 8 kingdoms and a Brahmin named Drona, who coordinated their distribution.
    • Each recipient built a Stupa to enshrine their share of the relics, creating important pilgrimage sites and early centers of Buddhist worship.
    • The 9 stupas were located in Rajagriha, Vaishali, Kapilavastu, Allakappa, Ramagrama, Vethadipa, Pava, Kushinagar, and Pippalivana.
    • Emperor Ashoka (3rd century BCE) redistributed the relics from these stupas into thousands of new stupas across his empire.
    • The stupa at Ramagrama is unique because it is believed to remain untouched and still holds the original relics.
    • A typical early Buddhist stupa included a hemispherical mound (anda), a square railing (harmika), a central pillar (yashti) with umbrellas (chatra), and a path for circumambulation (pradakshinapatha).
    [UPSC 2023] With reference to ancient India, consider the following statements:

    1. The concept of Stupa is Buddhist in origin.

    2. Stupa was generally a repository of relics.

    3. Stupa was a votive and commemorative structure in Buddhist tradition. How many of the statements given above are correct?

    Options: (a) Only one (b) Only two* (c) All three (d) None

     

  • IMF releases World Economic Outlook (WEO)

    Why in the News?

    The International Monetary Fund (IMF) has released the July 2025 update to its World Economic Outlook (WEO).

    IMF releases World Economic Outlook (WEO)

    About World Economic Outlook (WEO):

    • Published By: International Monetary Fund (IMF)
    • Frequency: Biannual (April, October) + updates in January and July
    • Purpose: Provides global forecasts on GDP, inflation, trade, and policy trends
    • Data Sources: IMF consultations with member nations and internal models
    • Audience: Governments, institutions, investors, researchers
    • July 2025 Update Title: “Global Economy: Tenuous Resilience amid Persistent Uncertainty”

    Key Highlights – July 2025 Update:

    • Global Growth Projections:
      • 2025: 3.0% (↑ from 2.8% in April)
      • 2026: 3.1% (↑ from 3.0%)
    • Despite multiple shocks—COVID-19, the Ukraine war, tariff increases—global growth continues.
      However, resilience remains fragile due to:

      • US–China tariff tensions and rising protectionism
      • Conflicts in Ukraine and the Middle East
      • High public debt in advanced economies is raising interest rates
    • Country Forecasts for 2025:  United States: 1.9%,  China: 4.8% (↑ from 4.0%),  Euro Area: 1.0%,  Germany: 0.1%,  United Kingdom: 1.2%,  Japan: 0.7%,  Russia: 0.9%,  Pakistan: 2.7%.

    India – The Bright Spot:

    • Growth Rate: 2023: 9.2%;  2024: 6.5%;  2025: 6.4% (strongest among major economies).
    • Drivers of Growth:
      • Robust domestic demand
      • Strong services and manufacturing output
      • Effective inflation and monetary policy management
    • Strategic Position:
      • Set to overtake several advanced economies in GDP size
      • Viewed globally as a “bright spot” amid persistent uncertainties
    [UPSC 2014] Which of the following organisations brings out the publication known as ‘World Economic Outlook?

    Options: (a) The International Monetary Fund * (b)The United Nations Development Programme (c) The World Economic Forum (d) The World Bank

     

  • What are Skill Impact Bonds (SIB)?

    Why in the News?

    Skill Impact Bonds (SIB) were recently highlighted by the Skill Development Ministry.

    About the Skill Impact Bond:

    • Launched: November 2021
    • Nature: India’s first Development Impact Bond (DIB) focused on employment-linked skill development
    • Lead Agency: National Skill Development Corporation (NSDC), under the Ministry of Skill Development and Entrepreneurship
    • Collaborators: British Asian Trust, HSBC India, Michael & Susan Dell Foundation
    • Target: Train and place 50,000 youth over 4 years, with 62% women participation
    • How it Works:
      • Risk Investors: Provide upfront capital to training providers
      • Training Providers: Deliver skill training and ensure job placements
      • Outcome Funders: Repay investors only if job outcomes are achieved
      • Evaluators: Independently assess outcomes via CATI surveys and document verification

    Key Features:

    • Outcome-Focused Approach: Measures success by certification, placement, and 3-month retention, not just enrolment
    • Eligibility Criteria:
      • Age: 18–40 years; Education: Undergraduate or below
      • Status: Unemployed or earning below ₹15,000/month, or household income below ₹25,000/month
    • Sectoral Coverage: Retail, Healthcare, Apparel, Logistics, Information Technology & IT-enabled Services, Banking, Financial Services & Insurance.
    • Women-Focused Design: Ensures 62% female participation to bridge the gender employment gap
    [UPSC 2018] With reference to Pradhan Mantri Kaushal Vikas Yojana, consider the following statements:

    1. It is the flagship scheme of the Ministry of Labour and Employment.

    2. It, among other things, will also impart training in soft skills, entrepreneurship, financial and digital literacy.

    3. It aims to align the competencies of the unregulated workforce of the country to the National Skill Qualification Framework.

    Which of the statements given above is/are correct?

    Options: (a) 1 and 3 only (b) 2 only (c) 2 and 3 only* (d) 1, 2 and 3

     

  • [pib] Digital Payments Index (DPI)

    Why in the News?

    According to the Reserve Bank of India (RBI), digital payments registered a 12.6% year-on-year rise as of March 31, 2024, as measured by the RBI’s Digital Payments Index (DPI).

    About RBI’s Digital Payments Index (DPI):

    • Launched by: Reserve Bank of India (RBI) in January 2021
    • Purpose: Measures the extent of digital payment adoption across India
    • Base Period: March 2018 (Index value = 100)
    • Release Frequency: Semi-annually (with a 4-month lag)
    • Objective: Track usage, infrastructure, and growth in digital payments
    • Key Parameters (with Weightage): These evaluate infrastructure readiness, transaction volume, user adoption, and innovation.
      1. Payment Enablers – 25%
      2. Payment Infrastructure – Demand Side – 10%
      3. Payment Infrastructure – Supply Side – 15%
      4. Payment Performance – 45%
      5. Consumer Centricity – 5%

    Growth Highlight:

    • Growth Trends in RBI-DPI: DPI grew nearly 5 times from 100 in March 2018 to 493.22 in March 2025, reflecting India’s rapid digital payment adoption.
    • Nearly 5× increase from the base value in 7 years
    • Driven by rapid expansion of Unified Payments Interface (UPI), mobile wallets, and QR code infrastructure
    [UPSC 2024] Consider the following countries:

    I. United Arab Emirates II. France III. Germany IV. Singapore V. Bangladesh

    How many countries amongst the above are there other than India where international merchant payments are accepted under UPI?”

    Options: (a) Only two (b) Only three* (c) Only four (d) All the five

    Answer: (b) Only three (UAE, France, Singapore)