Why in the News?
The Government of India has banned manufacture, sale and distribution of oral formulations of Nimesulide above 100 mg with immediate effect under Section 26A of the Drugs and Cosmetics Act, 1940.
About Nimesulide
Nimesulide is a Non Steroidal Anti Inflammatory Drug (NSAID) used for acute pain relief and fever reduction.
Key Features of the Drug
- Pharmacological class: NSAID
• Mechanism of action: Inhibits prostaglandin synthesis by blocking inflammatory chemical mediators
• Therapeutic use: Short term treatment of pain and fever
• Common side effects: Nausea, vomiting, diarrhoea, raised liver enzymes
• Known risk: Hepatotoxicity, especially at higher doses or prolonged use
Reason for the Ban
- Oral doses above 100 mg pose serious risk to liver health
• Increased incidence of drug induced liver injury
• Safer alternative analgesics available
• Action taken under Section 26A, which allows banning drugs harmful to public health
| [2019] Which of the following are the reasons for the occurrence of multi-drug resistance in microbial pathogens in India?
1. Genetic predisposition of some people 2. Taking incorrect doses of antibiotics to cure diseases 3. Using antibiotics in livestock farming 4. Multiple chronic diseases in some people Select the correct answer using the code given below. (a) 1 and 2 (b) 2 and 3 only (c) 1, 3 and 4 (d) 2, 3 and 4 |
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