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  • What is Next Generation Sequencing (NGS)?

    • To speed up testing as well as improve the accuracy of testing COVID-19, the CSIR is working on developing “mega labs” where large machines, called Next Generation Sequencing machines (NGS), will be used for sequencing human genomes.
    • It is repurposed to sequence 1,500-3,000 viral genomes at a go for detecting the SARS-CoV-2 novel coronavirus.

    Try this PYQ:

    What is Cas9 protein that is often mentioned in news? (CSP 2018)

    (a) A molecular scissors used in targeted gene editing

    (b) A biosensor used in the accurate detection of pathogens in patients

    (c) A gene that makes plants pest-resistant

    (d) A herbicidal substance synthesized in genetically modified crops

    What is NGS?

    • DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA.
    • It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine.
    • The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery.
    • Next-generation sequencing (NGS), also known as high-throughput sequencing, is the catch-all term used to describe a number of different modern sequencing technologies.
    • These technologies allow for sequencing of DNA and RNA much more quickly and cheaply than the previously used Sanger sequencing, and as such revolutionized the study of genomics and molecular biology.

    Benefits

    • The genome sequencing machines can substantially detect the possible presence of the virus even in several instances where the traditional RT-PCR tests miss out on them.
    • This is primarily because the RT-PCR test identifies the SARS-CoV-2 virus by exploring only specific sections of the virus.
    • Having an edge, the genome method can read a bigger chunk of the virus genome and thereby provide more certainty that the virus in question is indeed the particular coronavirus of interest.
    • It can also trace the evolutionary history of the virus and track mutations more reliably.

    Back2Basics:

    PCR Test for Diagnosis of the COVID-19

  • abscisic acid (ABA)

    A team of researchers at the Indian Institute of Science Education and Research (IISER), Bhopal, has conducted a study on seed germination that could have a major impact on agriculture.

    What is the study about?

    • The study aims to determine the optimum timing of seed germination and thus ensure high plant yields.
    • It focused on the interplay between plant hormones like abscisic acid (ABA) which inhibit the sprouting of the seed and environmental cues like light (which promotes the sprouting process) and darkness.

    Note the following plant hormones and their functions:

    Hormone

    Function
    Ethylene Fruit ripening and abscission
    Gibberellins Break the dormancy of seeds and buds; promote growth
    Cytokinins Promote cell division; prevent senescence
    Abscisic Acid Close the stomata; maintain dormancy
    Auxins Involved in tropisms and apical dominance

    What is Abscisic Acid? 

    • Humans have glands that secrete hormones at different times to stimulate body processes such as growth, development, and the breaking down of sugars.  
    • Plants also have hormones that stimulate processes that are necessary for them to live.  
    • Abscisic acid is a plant hormone involved in many developmental plant processes, such as dormancy and environmental stress response.  
    • Abscisic acid is produced in the roots of the plant as well as the terminal buds at the top of the plant. 

    Function of Abscisic Acid 

    Abscisic acid is involved in several plant functions.  

    • Plants have openings on the bottom side of their leaves, known as stomata. Stomata take in carbon dioxide and regulate water content. Abscisic acid has been found to function in the closing of these stomata during times when the plant does not require as much carbon dioxide or during times of drought when the plant cannot afford to lose much water through transpiration. 
    • One of the crucial functions of abscisic acid is to inhibit seed germination. Abscisic acid has been found to stop a seed from immediately germinating once it has been placed in the soil. It actually causes the seed to enter a period of dormancy.  
    • This is of great benefit to the plants because most seeds are formed at the end of the growing season, when conditions would not be favorable for a new plant to sprout. The abscisic acid causes the seed to wait until the time when conditions are more favorable to grow. This ensures greater success in the plant’s ability to grow and reproduce successfully. 
    • ABA functions in many plant developmental processes, including seed and bud dormancy, the control of organ size and stomatal closure. It is especially important for plants in the response to environmental stresses, including drought, soil salinity, cold tolerance, freezing tolerance, heat stress and heavy metal ion tolerance.

  • SPT0418-47: The Baby Milky Way

    SPT0418-47, a golden halo glinting 12 billion light-years away is the farthest galaxy resembling our Milky Way was recently spotted by astronomers.

    Try this PYQ:

    Which of the statements about black holes in space is/are correct?  (CSP 2016)

    1. It is a region in space where the pulling force of gravity is so strong that light is not able to escape.
    2. It can result from the dying stars.

    Select the correct answer using the code given below:

    (a) 1 only

    (b) 2 only

    (c) Both 1 and 2

    (d) Neither 1 nor 2

    SPT0418-47

    • The galaxy, called SPT0418-47, is so far away that it took billions of years for its light to reach Earth and so our image of it is from deep in the past.
    • It was picked up by the powerful Alma radio telescope in Chile using a technique called gravitational lensing, where a nearby galaxy acts as a powerful magnifying glass.
    • This was when the Universe was 1.4 billion years old — just 10% of its current age — and galaxies were still forming.
    • It has features similar to our Milky Way — a rotating disc and a bulge, which is the high density of stars packed tightly around the galactic centre.

    What makes it special?

    • This is the first time a bulge has been seen this early in the history of the Universe, making SPT0418-47 the most distant Milky Way look-alike.
    • Thus the infant star system challenges our understanding of the early years of the Universe.
    • Researchers expect these young star systems to be chaotic and without the distinct structures typical of mature galaxies like our Galaxy.
    • This unexpected discovery suggests the early Universe may not be as chaotic as once believed and raises many questions on how a well-ordered galaxy could have formed so soon after the Big Bang.

    Back2Basics: Milky Way

    • The Milky Way is the galaxy that contains our Solar System, with the name describing the galaxy’s appearance from Earth.
    • It appears like a hazy band of light seen in the night sky formed from stars that cannot be individually distinguished by the naked eye.
    • From Earth, the Milky Way appears as a band because its disk-shaped structure is viewed from within.
    • Galileo Galilei first resolved the band of light into individual stars with his telescope in 1610.
    • Until the early 1920s, most astronomers thought that the Milky Way contained all the stars in the Universe.
    • Following the 1920 Great Debate between the astronomers Harlow Shapley and Heber Curtis, observations by Edwin Hubble showed that the Milky Way is just one of many galaxies.

  • Species in news: Great Indian Hornbill

    A study based on satellite data has flagged a high rate of deforestation in a major hornbill habitat in Arunachal Pradesh.

    Try this PYQ:

    Q. In which of the following regions of India are you most likely to come across the ‘Great Indian Hornbill’ in its natural habitat? (CSP 2016)

    (a) Sand deserts of northwest India

    (b) Higher Himalayas of Jammu and Kashmir

    (c) Salt marshes of western Gujarat

    (d) Western Ghats

    About Great Indian Hornbill

    IUCN status: Vulnerable (uplisted from Near Threatened in 2018), CITES: Appendix I

    • The great hornbill (Buceros bicornis) also known as the great Indian hornbill or great pied hornbill, is one of the larger members of the hornbill family.
    • The great hornbill is long-lived, living for nearly 50 years in captivity.
    • It is predominantly fruit-eating, but is an opportunist and preys on small mammals, reptiles and birds.
    • Its impressive size and colour have made it important in many tribal cultures and rituals.
    • A large majority of their population is found in India with a significant proportion in the Western Ghats and the Nilgiris.
    • The nesting grounds of the birds in the Nilgiris North Eastern Range are also believed to support some of their highest densities.

    Their ecological significance

    • Referred to as ‘forest engineers’ or ‘farmers of the forest’ for playing a key role in dispersing seeds of tropical trees, hornbills indicate the prosperity and balance of the forest they build nests in.

    Threats

    • Hornbills used to be hunted for their casques — upper beak — and feathers for adorning headgear despite being cultural symbols of some ethnic communities in the northeast, specifically the Nyishi of Arunachal Pradesh.
    • Illegal logging has led to fewer tall trees where the bird’s nest.

    Back2Basics: Hornbill Festival

    • The Hornbill Festival is a celebration held every year from 1 – 10 December, in Kohima, Nagaland.
    • The festival was first held in the year 2000.
    • It is named after the Indian hornbill, the large and colourful forest bird which is displayed in the folklore of most of the state’s tribes.
    • Festival highlights include the traditional Naga Morungs exhibition and the sale of arts and crafts, food stalls, herbal medicine stalls, flower shows and sales, cultural medley – songs and dances, fashion shows etc.

  • 13th August 2020| Daily Answer Writing Enhancement

    Important Announcement:  Topics to be covered on 14th August-

    GS-1 Social empowerment, communalism, regionalism and secularism

    GS-4 Case Studies

    Question 1) 

    Chola bronze sculptures had set a new benchmark in the history of art and metallurgy”. Elucidate. 10 marks

    Question 2)

    Examine the role of the Supreme Court as the guardian of the Constitution with reference to the provisions in the Constitution. What are the challenges judiciary faces? 10 marks

     

    Question 3)

    How helpful the PMFBY has been to the farmers in fending off the risks? Assess the success of PMFBY and reasons for changes made in it by the roll-out of PMFBY 2.0. 10 marks

    Question 4)  

    “A man can live and be healthy without killing animals for food and on the contrary if he eats meat, he participates in killing animal merely for the sake of his appetite and to act so is immoral.” Do you agree with this view? Critically examine. 10 marks

     

     

    Reviews will be provided in a week. (In the order of submission- First come first serve basis). In case the answer is submitted late the review period may get extended to two weeks.

    *In case your answer is not reviewed in a week, reply to your answer saying *NOT CHECKED*. If Parth Sir’s tag is available then tag him.

    For the philosophy of AWE and payment, check  here: Click2Join

  • Perseids Meteor Shower

    The Perseids meteor shower is going to be active from August 17-26.

    Try this question from CSP 2014:

    Q.What is a coma, in the content of astronomy?

    (a) Bright half of material on the comet

    (b) Long tail of dust

    (c) Two asteroids orbiting each other

    (d) Two planets orbiting each other

    What is the Perseids meteor shower?

    • The Perseids meteor shower peaks every year in mid-August. It was first observed over 2,000 years ago.
    • The Perseids occur as the Earth runs into pieces of cosmic debris left behind by the comet Swift-Tuttle.
    • The cloud of debris is about 27 km wide, and at the peak of the display, between 160 and 200 meteors streak through the Earth’s atmosphere every hour as the pieces of debris.
    • They travel at the speed of some 2.14 lakh km per hour; burn up a little less than 100 km above the Earth’s surface.

    What are Meteor Showers?

    • Meteors are bits of rock and ice that are ejected from comets as they manoeuvre around their orbits around the sun.
    • As meteors fall towards the Earth, the resistance makes the space rocks extremely hot and, as meteorites pass through the atmosphere, they leave behind streaks of glowing gas that are visible to the observers and not the rock itself.
    • Meteor showers, on the other hand, are witnessed when Earth passes through the trail of debris left behind by a comet or an asteroid.
    • When a meteor reaches the Earth, it is called a meteorite and a series of meteorites, when encountered at once, is termed as a meteor shower.
    • According to NASA, over 30 meteor showers occur annually and are observable from the Earth.

    Where do the Perseids come from?

    • The comet Swift-Tuttle, which was discovered in 1862 by Lewis Swift and Horace Tuttle, takes 133 years to complete one rotation around the sun.
    • The last time it reached its closest approach to the sun was in 1992 and will do so again in 2125.
    • Every time comets come close to the sun, they leave behind dust that is essentially the debris trail, which the Earth passes through every year as it orbits around the Sun.

    Back2Basics:

     

  • 12th August 2020 | Prelims Daily with Previous Year Questions

    [WpProQuiz 500]

    [WpProQuiz_toplist 499]

  • Making sense of population growth of India

    The article analyses and explains the declining trend in India’s total fertility rate. The aspirational revolution in the parents explains such decline. 

    What the projections say

    • A new study was published in The Lancet, and prepared by the Seattle-based Institute for Health Metrics and Evaluation (IHME).
    • It argues that while India is destined to be the largest country in the world, its population will peak by mid-century.
    • And as the 21st century closes, its ultimate population will be far smaller than anyone could have anticipated, about 1.09 billion instead of approximately 1.35 billion today.
    • It could even be as low as 724 million, the study projects.
    • Until 2050, the IHME projections are almost identical to widely-used United Nations projections.
    •  It is only in the second half of the century that the two projections diverge with the UN predicting a population of 1.45 billion by 2100, and the IHME, 1.09 billion.

    Present trends in India’s fertility rate

    •  In the 1950s, India’s Total fertility rate (TFR) was nearly six children per woman; today it is 2.2.
    •  Between 1992 and 2015, it had fallen by 35% from 3.4 to 2.2.
    • It is even below the replacement rate in 18 States and Union Territories.

    What explains the trends

    • One might attribute it to the success of the family planning programme.
    • But family planning has long lost its primacy in the Indian policy discourse.
    • Punitive policies include denial of maternity leave for third and subsequent births, limiting benefits of maternity schemes and ineligibility to contest in local body elections for individuals with large families.
    • However, these policies are mostly ignored in practice.

    Aspirational revolution

    •  It seems highly probable that the socioeconomic transformation of India since the 1990s has played an important role.
    • Over the years parents began to rethink their family-building strategies.
    • Smaller families when compared with a bigger family with same income level, invest more money in their children by sending them to private schools and coaching classes.
    • It is not aspirations for self but that for children that seems to drive fertility decline.

    Consider the question “Examine the factors responsible for the declining trends in the total fertility rate for India. What are its implications for country?”

    Conclusion

    Demographic data suggest that the aspirational revolution is already under way. What we need to hasten the fertility decline is to ensure that the health and family welfare system is up to this challenge and provides contraception and sexual and reproductive health services that allow individuals to have only as many children as they want.

  • RBI revises guidelines for opening Current Accounts

    The article explains the salience of the RBI’s recent restriction on the opening of current accounts by the companies.

    Context

    • RBI has put restrictions on who can open a current account with which bank.

    What are the restrictions and why it matters

    • A company that has borrowed from a bank cannot open a current account with another bank.
    • It can open a current account with its lending banks under some circumstances.
    • Otherwise such company is encouraged to use the cash credit and overdraft facilities under which it has borrowed.

    Let’s understand why it matters

    • Firms borrow from PSU banks, but open current accounts with private or foreign banks.
    • When transactions move to current account of banks other than the lending bank, it loses visibility on end use of the funds.
    • Basically the PSU bank has no idea where the money has gone.
    • For example, when a firm gets money from its customers, instead of parking it with the lending bank it puts it in the current account with another bank.
    • The lending bank has no way of knowing if the loan is going bad wilfully or otherwise.

    Why private banks may oppose the move

    • Easy revenue source has got blocked.
    • They can, of course, start lending to firms to retain this business but that would mean taking risk.
    • It would be far safer to be with retail customers who have neither power nor lawyers to defend them against sharp banking practices.

    Why it matters to bank customers

    • Vanishing money raises the cost of funds to the bank and results in higher lending rates and lower deposit rates for us.
    • For taxpayers, it means regular use of our funds to recapitalize the banking system that periodically goes bankrupt due to loans gone bad.
    • So, an overall tightening of the system is great news.

    Conclusion

    For too long have the citizens been punished with greater scrutiny, tighter rules, higher costs and fewer benefits as compared to the suits. We should let the banks hand-wring, but celebrate the closure of each loophole as it happens.

    Back2Basics: What is the current account?

    • A current account is like a savings bank account, but with many facilities for swift and multiple transactions, overdraft facilities and it carries no interest.
    • Banks like to sell these accounts as they enjoy huge floats, or money that just sits with the bank waiting to be used by the depositing firms.

  • A candid chat with Raunak Agarwal, AIR 13, UPSC 2019 | UNHERD: Civilsdaily’s Topper series | Video inside

    Dear students,

    You all know Raunak Agarwal, the topper, AIR 13 in UPSC CSE 2019. But do you know how he thinks, what his thought process is and how he executes?

    Raunak Agarwal here in a frank conversation with Sukanya ma’am from Civilsdaily shared his thought process which drove him to AIR 13 in UPSC 2019. He even revealed many of his UPSC hacks ranging from 10 mins nap to the Prelims Grid system and more. Raunak was kind enough to share his poem on Women Empowerment as well (and yes he is awesome). Watch the video to know more about him.

    About Raunak Agarwal:

    He is academically accomplished, a topper throughout, he scored AIR 5 in CA finals, AIR 2 in IPCC, AIR 10 in CPT. Raunak is a B.Com graduate (of course, a gold medalist) from St. Xavier, Kolkata with an all-time highest CGPA (yeah that is still a record). He hails from Kolkata and will now be serving the country as an IAS. Raunak is an essayist, poet, and has been a teacher as well.

    Civilsdaily is proud of Raunak and wishes him the very best for his future.

    Unherd Topper Talk series is a Civilsdaily’s initiative. We want to highlight what makes these toppers, their approach and strategy different from the herd. And you will also be getting a sneak peek into the moments of their lives that are unheard of.

    Civilsdaily’s Samanvaya form for IAS exam 2020-21: https://bit.ly/Samnvya (We’ll call you)

    Want to see your name in the final list but facing issues like figuring out a successful strategy, or have no guidance, or lack discipline.

    Aspirants, be it at any stage of preparation have a number of questions like: How to start? When to start writing answers? How and from where to cover current affairs? When to start mains? and a lot more of them.

    Well, Don’t keep these questions with you. We are here for you. Let’s talk and discuss.

    Fill this Civilsdaily’s Samanvaya form for IAS exam 2020-21: https://bit.ly/Samnvya (We’ll call you)

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