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Subject: Science and Technology

  • Rising Cancer Cases in India And Economic Burden

    Central Idea

    • Cancer cases in India are predicted to cross the 15 lakh mark by 2025, highlighting concerns about the economic burden of expensive cancer treatments and the accessibility of affordable healthcare for patients.

    Cancer

    • Cancer is a group of diseases that arise when cells in the body begin to grow and divide uncontrollably, leading to the formation of tumors.
    • Normally, cells in the body grow, divide, and die in an orderly fashion, but in cancer, this process goes awry, leading to the accumulation of abnormal cells that can form a mass or tumor.
    • There are many different types of cancer, which can affect any part of the body. Some cancers, such as leukemia, do not form tumors but still involve the uncontrolled growth of abnormal cells.
    • Symptoms of cancer can vary depending on the type and location of the cancer, but common signs include unexplained weight loss, fatigue, pain, and changes in the skin or the appearance of a lump or mass.

    Economic Burden of Cancer Treatment

    1. Inaccessible and Increasing Costs:
    • The average medical expenditure per hospitalization case for cancer treatment was ₹68,259 in urban areas, according to the NSS 2017-18 report.
    • A Parliamentary Standing Committee report expressed concern about the inaccessible and increasing cost of cancer treatment.
    1. Regulatory Challenges:
    • While anti-cancer medicine costs can be regulated, the cost of radiotherapy cannot, as it has not been declared an essential service.
    • Insurance Coverage and Out-of-Pocket Expenses.
    1. Impact on Patients:
    • Cancer often strikes around the retirement age, leading to mounting debt burdens.
    • The average hospital stay for 14.1% of cancer patients is more than 30 days, further increasing bills.

    Insurance Coverage and Out-of-Pocket Expenses

    1. Poor Insurance Penetration: More than 80% of hospital bills are paid out of pocket, as per the NSS 2017-18 report.
    2. Ayushman Bharat Limitations: The Committee observed that the Ayushman Bharat insurance scheme launched in 2018 does not cover entire prescriptions, latest cancer therapies, or many diagnostic tests.
    3. State-Specific Insurance Schemes: The Committee suggested a convergence of State and Central schemes, as some State-specific insurance schemes have been highly beneficial.

    State-wise Variation in Cancer Treatment Expenditure

    • State-wise average medical expenditure per hospitalization case for cancer treatment in government hospitals varies, with the lowest in Tamil Nadu and Telangana, and the highest in northern and north-eastern India.

    Facts for Prelims: CAR T-cell therapy

    • Unlike chemotherapy or immunotherapy, which require mass-produced injectable or oral medication, CAR T-cell therapies use a patient’s own cells.
    • The treatment involves modifying a patient’s own T-cells, which are a type of immune cell, in a laboratory to target and attack cancer cells.
    • CAR stands for chimeric antigen receptor, which refers to the genetically engineered receptor that is added to the patient’s T-cells.
    • The patient’s T-cells are collected and genetically modified in a laboratory to express the CAR.
    • The modified T-cells are then infused back into the patient’s body, where they can seek out and destroy cancer cells that express the antigen targeted by the CAR.
    • The cells are even more specific than targeted agents and directly activate the patient’s immune system against cancer, making the treatment more clinically effective.
    • This is why they’re called living drugs.
    • CAR T-cell therapy has shown promising results in treating certain types of blood cancers, including leukemia and lymphoma.

    Conclusion

    • The rising number of cancer cases in India underscores the need to address the economic burden of expensive cancer treatments and improve the accessibility of affordable healthcare for patients. Converging State and Central insurance schemes, expanding insurance coverage, and exploring ways to regulate treatment costs are essential steps to ensure that patients can access life-saving treatments without facing insurmountable financial challenges.
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  • World’s 1st Sand Battery developed in Finland

    sand

    Finland has successfully installed the world’s first sand battery that can store heat from various energy sources for months.

    What is the Sand Battery System?

    • The battery is a massive steel silo, 7 m tall and 4 m wide with 100 tonnes of sand, and was installed in Finland’s Kankaanpaa town in June 2022.
    • It is connected to the town’s centralised heating network that keeps buildings and public water systems warm.
    • The storage system has three main components:
    1. Sand silo,
    2. Electrical air heater, and
    3. Air-to-water heat exchanger

    Working principle

    • For charging the sand silo, air is heated to 600°C in the electrical air heater.
    • The hot air is then circulated inside the silo using a heat-exchange pipe and blowers to raise the temperature of the sand at the silo’s core to 600°C.
    • When the storage enters the discharging stage, the blowers are used to pump air into the pipe inside the sand silo.
    • Once the air reaches 200°C, it is transferred to the air-to-water heat exchanger, where it is used to boil water.
    • It is then sent to the heating network.

    Electricity Requirements and Capacity of the Battery

    • The storage system requires electricity at all times to charge the battery, monitor the temperature during standby, and run the blowers when the battery is used.
    • The installed battery can store 8 megawatt-hours (MWh) of energy and release heat at 0.1 MW, which is enough to provide heating and hot water for about 100 homes and a public swimming pool.

    Advantages of Sand as a Heat Storage Material

    • The Finnish researchers replaced water with sand in the battery system because of its advantages.
    • Sand can be heated up to 600 degrees Celsius (°C), whereas water starts to boil at 100°C.
    • It also has low heat conductivity, which reduces energy loss.

    Importance of Heat Energy

    • Heat accounts for half of the world’s energy use, followed by transport (30 per cent) and electricity (20 per cent), as per the International Energy Agency (IEA).
    • Currently, 80 per cent of the world’s energy comes from dirty fossil fuels.

     

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  • What is Generative AI?

    generative ai

    Central idea: Google and Microsoft have added generative AI to their search engines and browsers, as well as to consumer products such as Gmail, Docs, Copilot 365, Teams, Outlook, Word, Excel, and more.

    What is Generative AI?

    • Like other forms of artificial intelligence, generative AI learns how to take actions from past data.
    • It creates brand new content – a text, an image, even computer code – based on that training, instead of simply categorizing or identifying data like other AI.
    • The most famous generative AI application is ChatGPT, a chatbot that Microsoft-backed OpenAI released late last year.
    • The AI powering it is known as a large language model because it takes in a text prompt and from that writes a human-like response.

    Generative AI products offered by Google and Microsoft

    generative ai

    • Google and Microsoft have added generative AI to their search engines and browsers, as well as to consumer products such as Gmail, Docs, Copilot 365, Teams, Outlook, Word, Excel, and more.
    • In Google’s Gmail and Docs, generative AI can help users write documents automatically, such as a welcome email for employees.
    • Copilot 365, a feature of Microsoft 365 apps, can generate spreadsheets on command or even write an entire article on Word, depending on the topic.
    • Both companies are making generative AI platforms and models a part of their cloud offerings, Microsoft Azure and Google Cloud.

    What are Google and Microsoft offering?

    • In Google’s Gmail and Docs, generative AI will help users write documents automatically.
    • For instance, an HR executive can simply ask the AI app to write a welcome email for employees, instead of typing out the document.
    • Similarly, Microsoft has ‘Copilot 365’ for its Microsoft 365 apps, which includes Teams, Outlook, Word and Excel.
    • Here, AI could generate a spreadsheet on command, or even write down an entire article on Word (depending on the topic).
    • Copilot can also match entries on Calendar with emails, and generate quick, helpful pointers that a person should focus on in their meetings.

    How can these developments impact human workforce?

    • The technology is currently not very accurate and often provides incorrect responses, despite being popular.
    • During the initial demonstrations of these products, Google and Microsoft were found to give inaccurate responses.
    • While these products may have utility, they are not yet capable of replacing humans in the workplace.
    • Humans are better suited to check information generated by AI.

    Various challenges posed

    • Bias: The data that is used to train generative AI systems can be biased, leading to biased outputs.
    • Misinformation: Since generative AI systems learn from the internet or training data which itself may have been inaccurate, they could increase the spread of misinformation online.
    • Security: Generative AI systems could be used to create deepfakes or other forms of digital manipulation that could be used to spread disinformation or commit fraud.
    • Ethics: There are ethical concerns around the use of generative AI, particularly when it comes to issues like privacy, accountability, and transparency.
    • Regulation: There is a need for regulatory frameworks to ensure that generative AI is used responsibly and ethically, and that it does not have any negative impacts on society.

     

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  • Background Radiation high in Kerala: Study

    Central idea: The article discusses a pan-India study conducted by scientists at the Bhabha Atomic Research Centre (BARC) which found that background radiation levels in parts of Kerala are nearly three times more than what’s been assumed.

    What is Background Radiation?

    • Background radiation is a measure of the level of ionizing radiation present in the environment at a particular location which is not due to deliberate introduction of radiation sources.
    • Background radiation originates from a variety of sources, both natural and artificial.

    Nuclear Radiation and its Types

    radiation

    There are three main types of nuclear radiation: alpha particles, beta particles, and gamma rays.

    1.      Alpha particles are made up of two protons and two neutrons and are essentially helium nuclei. They have a positive charge and are relatively large and heavy, which means they can be stopped by a piece of paper or the outer layer of skin.

    2.      Beta particles are high-energy electrons that are emitted from the nucleus of an atom. They have a negative charge and are much smaller than alpha particles, which means they can penetrate through the skin and into the body.

    3.      Gamma rays are high-energy electromagnetic radiation, similar to X-rays. They are emitted from the nucleus of an atom and have no charge. They are extremely penetrating and can travel long distances through air and most materials, including the human body.

     

    How is it measured?

    • The International Atomic Energy Agency (IAEA) specifies maximum radiation exposure levels and this has also been adopted by India’s atomic energy establishment.
    • Public exposure shouldn’t exceed 1 milli-Sievert every year, those who work in plants or are by virtue of their occupation shouldn’t be exposed to over 30 milli-Sievert every year.
    • Generally it is measured in nanogray per second. A (nGy/s) is a decimal fraction of the SI-derived unit of ionizing radiation absorbed dose rate.

    Natural sources-

    1. Cosmic radiation
    2. Environmental radioactivity from naturally occurring radioactive materials (such as radon and radium)

    Man-made sources-

    1. Medical X-rays,
    2. Fallout from nuclear weapons testing and nuclear accidents.

    Factors affecting such radiation

    • Natural background radiation is all around us.
    • Background radiation varies from place to place and over time, depending on the amount of naturally occurring radioactive elements in soil, water and air.
    • Weather conditions also affect radiation levels, as snow cover may shield these elements, and radioactive particulates can wash out of the air during rain storms.
    • Cosmic radiation from the sun, our galaxy, and beyond is constantly around us and contributes to natural background radiation.
    • Altitude and latitude can also influence the level of background radiation at any one site.

    How threatening is it?

    • All rocks and soils contain some trace amount of natural radioactivity and can sometimes be ingested or inhaled if disturbed.
    • Radon is a gas that can concentrate indoors and be inhaled, along with its decay products.
    • We can also ingest radioactivity from the food we eat and the water we drink.
    • A number of factors determine the annual dose you and your family receive from background radiation.
    • Typically, Gamma rays are a type of such radiation that can pass through matter unobstructed, and are harmless in small doses, but can be dangerous in concentrated bursts.

    Findings of the BARC Study

    • The study found that the average natural background levels of gamma radiation in India was 94 nGy/hr (nano Gray per hour) (or roughly 0.8 millisievert/year).
    • The last study conducted in 1986 computed such radiation to be 89 nGy/hr.
    • The study found that the levels in Kollam district, Kerala were 9,562 nGy/hr, or about three times more than what was assumed.
    • This computes to about 70 milliGray a year, or a little more than what a worker in a nuclear plant is exposed to.
    • This however does not necessarily mean that those at Kollam are being exposed to dangerous levels of radiation, as past studies have not found any higher rates of cancer or mortality.

    Reasons for Higher Radiation Levels in Kerala

    • The higher radiation levels in Kollam are attributed to monazite sands that are high in thorium, which is part of India’s long-term plan to sustainably produce nuclear fuel.
    • Southern India has higher levels of radiation due to the presence of granite and basaltic, volcanic rock, which contains uranium deposits.

     

     

  • Starberry-Sense: A low cost Star Sensor

    star

    Researchers at the Indian Institute of Astrophysics (IIA) have developed a low-cost star sensor for astronomy and small CubeSat class satellite missions.

    What is Starberry-Sense?

    • Based on commercial/off-the-shelf components, this star sensor costs less than 10% of those available in the market.
    • It is made from a single-board Linux computer called Raspberry Pi, which is widely used among electronics hobby enthusiasts.

    Benefits of Starberry-Sense

    • Starberry-Sense can help small CubeSat class satellite missions find their orientation in space.
    • The instrument can be used for CubeSats and other small satellite missions in the future.
    • The position of stars in the sky is fixed relative to each other and can be used as a stable reference frame to calculate the orientation of a satellite in orbit.

    Successful test

    • The star sensor has successfully undergone the vibration and thermal vacuum test that qualifies it for a space launch and operations.
    • These tests were conducted in-house at the environmental test facility located at the CREST Campus of IIA in Hosakote.

     

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  • Low Temperature Thermal Desalination (LTTD) Technology

    desalin-lttd

    The National Institute of Ocean Technology (NIOT) is making efforts to make its ongoing water provision project in Lakshadweep eco-friendly by eliminating emissions in its Low Temperature Thermal Desalination technology.

    What is LTTD Technology?

    • LTTD Technology is a desalination process that uses low-grade thermal energy, typically below 70°C, to evaporate seawater and produce fresh water.
    • The technology is designed to be efficient and cost-effective, and it has been successfully used in various locations worldwide to provide potable water.

    How does LTTD Technology work?

    • LTTD Technology works by using a low-grade thermal source, such as warm seawater, to heat up a chamber containing seawater.
    • As the seawater is heated, it evaporates and produces fresh water vapor.
    • The vapor is then condensed and collected, leaving behind concentrated seawater, which can be discharged back into the ocean.
    • The fresh water produced can be used for various purposes, such as drinking water, irrigation, or industrial applications.

    Benefits of this technology

    • One of the main benefits of LTTD Technology is that it uses low-grade thermal energy, which is readily available in many locations, especially in coastal areas.
    • This makes it a cost-effective and sustainable way of producing fresh water.
    • Additionally, LTTD Technology is modular and can be easily scaled up or down, depending on the water demand.
    • It also has a relatively low environmental impact compared to other desalination technologies.

    Challenges of LTTD Technology

    • One of the main challenges of LTTD Technology is that it requires a constant source of low-grade thermal energy, which can be affected by weather conditions and seasonal changes.
    • Additionally, the technology is relatively new and may require further research and development to optimize its efficiency and performance.

    How is NIOT working to make LTTD Technology emission-free?

    • NIOT is working on making LTTD Technology emission-free by using renewable energy sources, such as solar energy, to power the desalination process.
    • The goal is to reduce the carbon footprint of the technology and make it more sustainable and environmentally friendly.

    Try this MCQ:

    Q. The LTTD technology involves the use of which of the following processes to produce potable water?

    A) Reverse osmosis B) Distillation C) Filtration D) Chlorination

    [wpdiscuz-feedback id=”203h5ffv8o” question=”Please leave a feedback on this” opened=”1″]Post your answer here.[/wpdiscuz-feedback]

     

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  • What is GPT-4 and how is it different from ChatGPT?

    gpt

    Central idea: OpenAI announced GPT-4 as the next big update to the technology that powers ChatGPT and Microsoft Bing.

    What is GPT-4?

    • GPT-4 is a large multimodal model created by OpenAI that accepts images as input, making it a more advanced version of GPT-3 and GPT-3.5.
    • It exhibits human-level performance on various professional and academic benchmarks, and it can solve difficult problems with greater accuracy.

    How is GPT-4 different from GPT-3?

    • GPT-4 is multimodal, allowing it to understand more than one modality of information, unlike GPT-3 and GPT-3.5, which were limited to textual input and output.
    • It is harder to trick than previous models, and it can process a lot more information at a time, making it more suitable for lengthy conversations and generating long-form content.
    • It has improved accuracy and is better at understanding languages that are not English.

    GPT-4’s abilities

    • GPT-4 can use images to generate captions and analyses, and it can answer tax-related questions, schedule meetings, and learn a user’s creative writing style.
    • It can handle over 25,000 words of text, opening up a greater number of use cases that include long-form content creation, document search and analysis, and extended conversations.
    • It significantly reduces hallucinations and produces fewer undesirable outputs, such as hate speech and misinformation.

    Multilingual abilities of GPT-4

    • GPT-4 is more multilingual and can accurately answer thousands of multiple-choice questions across 26 languages.
    • It handles English best, with an 85.5% accuracy, but Indian languages like Telugu aren’t too far behind either, at 71.4%.

    Availability of GPT-4

    • GPT-4 has already been integrated into products like Duolingo, Stripe, and Khan Academy for varying purposes.
    • Image inputs are still a research preview and are not publicly available.
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  • Scientists devise ‘Glowscope’ to bring fluorescent microscopy to schools

    microscope

    Central idea: Researchers at Winona State University, Minnesota, have created a design for a rudimentary fluorescence microscope.

    Why in news?

    • The development can be put together at a cost of $30-50 (Rs 2,500-4,100) using products purchased on online marketplaces.
    • The device aims to democratize access to fluorescence microscopy.

    What is Fluorescence Microscopy?

    • An optical microscope views an object by studying how it absorbs, reflects or scatters visible light.
    • A fluorescence microscope views an object by studying how it reemits light that it has absorbed, i.e. how it fluoresces.
    • The object is illuminated with light of a specific wavelength.
    • Particles in the object absorb this light and reemit it at a higher wavelength.
    • These particles are called fluorophores; the object is infused with them before being placed under the microscope.

    How does it work?

    • The setup consists of two plexiglass surfaces, an LED flashlight, three theatre stage-lighting filters, a clip-on macro lens, and a smartphone.
    • The smartphone (with the lens attached) is placed on one surface that is suspended at a height (say, a foot above).
    • The second sheet is placed below and holds the object.
    • One of the stage-lighting filters is held between the flashlight and the object and the other two were held between the object and the smartphone.
    • The sources of illumination were also LED flashlights emitting light of correspondingly different wavelengths.

    Key observations

    • With this setup, the researchers were able to image the creatures’ brain, spinal cord, heart, and head and jaw bones.
    • They were able to zoom in and out using the smartphone camera and the clip-on lens.

    How accessible is this?

    • Using a ‘glowscope’ still requires access to fluorophores, suitable biological samples, the know-how to combine the two, and some knowledge of physics to work out which LED flashlight to buy.
    • The Foldscope was truly remarkable because all its required components were simple to understand.
    • However, the fact that a simple fluorescent microscope can be set up with a few thousand rupees means researchers can prepare samples and take them to schools, where students can observe them.
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  • In news: Megha Tropiques Satellite

    sat

    ISRO attempted a controlled re-entry of the Megha Tropiques-1 satellite with leftover fuel to lower the orbit and reduce space debris.

    Megha Tropiques Satellite

    • The weather satellite Megha Tropiques-1 was developed as a joint mission by Indian and French space agencies.
    • It was launched aboard a PSLV by the space agency in 2011.
    • And, although the planned mission life of the satellite was only three years, it continued providing data on water cycle and energy exchanges in the tropics for nearly a decade.

    How was the satellite brought down?

    • With over 120kgs of fuel remaining in the satellite even after being decommissioned.
    • ISRO determined that there was enough to attempt a controlled re-entry.
    • When the satellites re-enter the atmosphere, the friction causes it to heat up to extreme high temperatures of thousands of degrees Celsius.
    • Without a heat shield, 99% of a satellite gets burnt up whether in a controlled re-entry or an uncontrolled one.

    Significance of the move

    • This was the first time that ISRO attempted such a manoeuvre to clear out space debris despite the satellite not being built to do so.
    • Usually, satellites are left in their orbit and because of the gravitational pull of the earth, they come down to the atmosphere over years and years.

    Why did ISRO attempt a controlled re-entry?

    • ISRO attempted the control re-entry to demonstrate and understand the process of doing so.
    • Keeping space clean is crucial with multiple spacefaring nations and private entities launching satellites.
    • Thousands of objects are flying around in low earth orbits, including old satellites, parts, and rocket stages.
    • Even small debris can destroy active satellites due to high speeds.
    • Kessler syndrome is a scary scenario where space debris collisions create more debris.

    What happens to satellites usually?

    • A controlled re-entry like the one attempted by Isro earlier this week is possible only for satellites in the low-earth orbit – at about 1,000 kms over the surface of the earth.
    • These manoeuvres, however, are not usually attempted because fuel reserves have to be maintained in the satellite after mission life is over.
    • And, this is impossible for satellites placed in geo-stationary or geosynchronous orbit – where time taken by the satellite to orbit the earth matches Earth’s rotation.
    • Such satellites are at altitudes of nearly 36,000 kms.
    • For attempting to bring down a satellite from such as orbit, a huge fuel reserve would be needed. This will only make the satellite heavier and costlier at launch.

    Also read-

    [Sansad TV] Perspective: Cluttered Space

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  • NASA’s IBEX spacecraft to study Edge of Solar System

    ibex

    NASA has announced that its Interstellar Boundary Explorer (IBEX) spacecraft is fully operational after the mission team successfully reset it.

    Edge of Solar System: Heliopause

    ibex

    The edge of the Solar System, also known as the heliopause, is the point where the solar wind from the Sun meets the interstellar medium. Here are some key points about the edge of the Solar System:

    • The heliopause is the boundary where the Sun’s solar wind is stopped by the interstellar medium.
    • The Voyager 1 spacecraft crossed the heliopause in 2012, becoming the first man-made object to leave the Solar System.
    • The exact location of the heliopause is not well defined and varies based on the strength of the solar wind and the density of the interstellar medium.
    • The interstellar medium beyond the heliopause is composed of plasma, magnetic fields, and cosmic rays from other stars in the Milky Way galaxy.
    • The edge of the Solar System is being studied by NASA’s Interstellar Boundary Explorer (IBEX) mission, which is mapping the boundary region where the solar wind meets the interstellar medium.

    Interstellar Boundary Explorer (IBEX)

    • IBEX is a small NASA spacecraft designed to map the boundary where winds from the Sun interact with winds from other stars.
    • The spacecraft is about the size of a bus tire and its instruments look towards the interstellar boundary while it is on its nine-day orbit around our planet.
    • It was launched in 2008 and has spent nearly 15 years in space already.

    Purpose

    • The purpose of IBEX is to study the interaction between the solar wind and the interstellar medium and to map the boundary of the solar system.

    Technology

    • IBEX uses two neutral atom imaging cameras to detect energetic neutral atoms that are created at the boundary of the heliosphere.
    • The cameras are mounted on a spinning spacecraft, allowing them to scan the sky and build up a map of the boundary.

    Discoveries

    Since its launch, IBEX has made several important discoveries, including:

    • The first direct measurements of the interstellar wind, which flows into the solar system from the direction of the constellation Scorpius.
    • The discovery of a “ribbon” of energetic neutral atoms that stretches across the sky, which may be caused by the interaction between the solar wind and the interstellar medium.

    Current Status

    • IBEX is still in operation and continues to gather data about the interstellar boundary.
    • Its mission has been extended several times, with the most recent extension running until 2023.

    Significance

    • IBEX’s findings have increased our understanding of the interaction between the solar wind and the interstellar medium.
    • It has helped to refine models of the heliosphere and the solar system’s place in the galaxy.
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