Innovations in Biotechnology and Medical Sciences

Endocrine Disruptors in Plastic Waste

Why in the News?

Microplastics and endocrine-disrupting chemicals (EDCs) are infiltrating the human body, affecting everything from reproduction to cancer risk, metabolism, and child development.

About Endocrine-Disrupting Chemicals:

  • What They Are: Endocrine-Disrupting Chemicals interfere with the body’s hormone system, affecting growth, reproduction, mood, and metabolism.
  • How They Work: They mimic or block natural hormones like estrogen, testosterone, thyroid hormones, and cortisol, leading to disrupted hormonal signals.
  • Why They’re Dangerous: Even low-level exposure during pregnancy or puberty can cause lasting harm.
  • How We’re Exposed: Through eating contaminated food, inhaling polluted air, or skin contact with certain plastics or cosmetics.
  • Where They’re Found: In plastic bottles (Bisphenol A), toys and cosmetics (phthalates like Di(2-ethylhexyl) phthalate), food wrappers (Per- and Polyfluoroalkyl Substances), and pesticides (dioxins, Polychlorinated Biphenyls).
  • Hidden Harm: They act silently, with long-term effects such as fertility loss, hormonal disruption, or cancer.

Impact on Human Health:

  • Reproductive Harm: Reduced sperm quality disrupted menstrual cycles, and increased miscarriage risk. Found in semen, placenta, and breast milk.
  • Hormonal Disruption: Chemicals like Bisphenol A trigger early puberty, thyroid issues, and hormonal imbalances.
  • Cancer Risk: Linked to cancers of the breast, uterus, testicles, and prostate. Several are labeled probable carcinogens by global health agencies.
  • Metabolic Effects: Interfere with insulin, promote obesity and type 2 diabetes. PFAS chemicals are linked to liver and heart disease.
  • Brain and Behavior: Associated with ADHD, learning issues, and lower IQ in children, especially when exposure happens early in life.
  • Across Generations: May cause gene expression changes that affect health in future generations—even without direct exposure.
[UPSC 2020] Why is there a great concern about the ‘microbeads’ that are released into environment?

Options: (a) They are considered harmful to marine ecosystems * (b) They are considered to cause skin cancer in children (c) They are small enough to be absorbed by crop plants in irrigated fields. (d) They are often found to be used as food adulterants.

 

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