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Distribution: yearly

  • Egypt attains WHO ‘Gold Tier’ status in Hepatitis C Elimination

    Central Idea

    • Egypt has become the first country to achieve the World Health Organization’s “gold tier” status on the path to elimination of Hepatitis C.

    About Hepatitis

    Hepatitis A Hepatitis B Hepatitis C
    Causative Virus Hepatitis A Virus (HAV) Hepatitis B Virus (HBV) Hepatitis C Virus (HCV)
    Transmission Fecal-oral route (contaminated food/water) Blood and body fluids (unsafe sex, sharing needles) Blood-to-blood contact (sharing needles, transfusions)
    Vaccine Available Yes Yes Yes
    Chronic Infection No (usually acute) Yes (can become chronic) Yes (often becomes chronic)
    Symptoms Mild flu-like symptoms, jaundice Variable, from none to severe symptoms Often asymptomatic, but can lead to liver damage
    Chronic Complications None Cirrhosis, liver cancer Cirrhosis, liver cancer
    Preventable by Vaccine Yes Yes No
    Treatment Supportive care Antiviral medications Antiviral medications

     Egypt’s “Gold Tier” Status

    • Stringent Criteria: To reach the “gold tier,” Egypt fulfilled specific criteria, including ensuring 100% blood and injection safety, providing a minimum of 150 needles/syringes annually for people who inject drugs, diagnosing over 80% of individuals with chronic hepatitis C virus (HCV), treating over 70% of diagnosed HCV patients, and establishing a surveillance program for hepatitis sequelae, including liver cancer.
    • Exemplary Results: Egypt has diagnosed 87% of its hepatitis C patients and provided curative treatment to 93% of those diagnosed, surpassing the WHO’s gold tier targets.

    How did Egypt achieve this?

    • “100 Million Healthy Lives” Initiative: Egypt’s ambitious initiative led to a substantial reduction in hepatitis C prevalence, from 10% in 2016 to 5% in 2018 and an estimated less than 1% in 2019, as reported by the Africa CDC.
    • Leadership Role: Egypt extends support to other African countries, aiming to replicate its success in hepatitis C elimination, including enhancing access to affordable treatment.

    Try this PYQ:

    Which one of the following statements is not correct?

    (a) Hepatitis B virus is transmitted much like HIV.

    (b) Hepatitis B, unlike Hepatitis C, does not have a vaccine.

    (c) Globally, the number of people infected with Hepatitis B and C viruses are several times more than those infected with HIV.

    (d) Some of those infected with Hepatitis B and C viruses do not show the symptoms for many years.

     

    [wpdiscuz-feedback id=”q4k2t2jv1z” question=”Please leave a feedback on this” opened=”1″]Post your answers here.[/wpdiscuz-feedback]

  • India-Sri Lanka Ferry Service

    India-Sri Lanka Ferry Service

    Central Idea

    • PM Modi inaugurated an international, high-speed passenger ferry service in Palk Strait between Nagapattinam in Tamil Nadu, India, and Kankesanthurai, near Jaffna in Sri Lanka.

    India-Sri Lanka Ferry

    • The service is operated by the Tamil Nadu Maritime Board and Shipping Corporation of India.
    • It will operate daily, covering the 60-nautical mile (110-km) journey in approximately 3.5 hours.
    • Passengers are entitled to a 50kg free baggage allowance.
    • The Indo-Ceylon Express or Board Mail used to operate between Chennai and Colombo via Thoothukudi port.
    • However, this was stopped in 1982 due to the civil war in the island country.

    About Palk Strait

    Location Narrow water body separating Tamil Nadu, India, and Sri Lanka.
    Name Origin Named after Robert Palk, a British Raj-era governor of Madras Presidency (1755-1763).
    Geographic Boundaries Southern boundaries include Pamban Island (India), Adam’s Bridge (shoals), Gulf of Mannar, and Mannar Island (Sri Lanka).
    Connection Connects the Bay of Bengal in the northeast with the Gulf of Mannar in the southwest.
    Alternate Name Southwestern part of the strait is known as Palk Bay.
    Dimensions Width varies from 40 to 85 miles (64 to 137 km), length is approximately 85 miles, and depth is less than 330 feet (100 meters).
    River Inflows Vaigai River in Tamil Nadu flow into the Palk Strait.

  • Disruption in Earth’s Water Cycle

    water cycle

    Central Idea

    • The World Meteorological Organization (WMO) issued a report highlighting the significant impact of climate change and human activities on Earth’s water circulation systems.
    • This has direct consequences leading to droughts, extreme rainfall events, and disruptions in water cycles.

    What is the Water Cycle?

    • The water cycle, also known as the hydrologic cycle, is the continuous movement of water on, above, and below the Earth’s surface.
    • It involves various processes that allow water to circulate between the atmosphere, land, oceans, and other bodies of water:
    Evaporation Sun’s heat turns surface water into vapor.
    Condensation Vapor forms clouds as it cools in the atmosphere.
    Precipitation Clouds release moisture as rain, snow, or hail.
    Runoff & Infiltration Water flows over land or seeps into the ground.
    Transpiration Plants absorb and release water vapor.
    Sublimation Ice transforms directly into vapor in specific conditions.
    Transport Winds move moisture globally.
    Collection Water gathers in oceans, lakes, and underground sources.

     Why is it under stress?

    • Diverse Impact: Climate change and human activities have led to an erratic hydrological cycle, resulting in both droughts and extreme rainfall events, causing widespread disruptions affecting livelihoods and economies.
    • Melting Snow and Glaciers: Ongoing melting of snow, ice, and glaciers further exacerbates the risk of extreme weather events, such as floods, posing long-term threats to water security, particularly for millions already facing severe water scarcity.

    Global Impact

    • Global Deviations: Over 50% of global catchment areas experienced deviations from normal river discharge conditions in 2022, primarily due to climate anomalies, such as heatwaves, droughts, La Nina, and El Nino events.
    • Horn of Africa Drought: Severe drought in the Horn of Africa led to reduced river discharge, affecting food security for 21 million people, while other regions, like the Niger Basin, saw above-average discharge and major floods.
    • Water Reservoirs Affected: More than 60% of major water reservoirs experienced below-normal inflow, posing challenges to water availability in a changing climate.

    Impact on Asian Water Tower

    • The term “Asian Water Tower (AWT)” typically refers to the vast network of high mountain regions across Asia, particularly in countries like India, China, Nepal, Bhutan, and parts of Central Asia.
    • These high mountain regions are the source of many major rivers in Asia, such as the Ganges, Brahmaputra, Yangtze, Mekong, Indus, and Amu Darya.
    • The melting snow and glaciers in these mountains provide a continuous supply of freshwater to downstream areas.
    • This AWT witnessed substantial glacial melting in 2022.
    • Rising temperatures accelerate water cycle disruptions, leading to heavier precipitation, flooding, and intensified droughts, significantly impacting the water balance.

  • India seeks inclusion of Traditional Medicine on WHO’s ICD List

    Central Idea

    • The Centre seeks to include traditional Indian medicines in the 11th revision of the World Health Organisation’s International Classification of Diseases (ICD).
    • The traditional Indian medicine system is categorized into Ayurveda, Siddha, Unani and Yoga, Naturopathy, and Homoeopathy

    About International Classification of Diseases (ICD)

    Purpose Standardized system for classifying and coding diseases, health conditions, and related information.
    Established 1893, by International Statistical Institute (WHO’s predecessor)
    Authority Developed and maintained by the World Health Organization (WHO).
    Scope Covers a wide range of diseases, health conditions, injuries, and health-related factors.
    Coding System Assigns unique alphanumeric codes to each health condition for consistent recording and reporting.
    Global Applicability Internationally recognized and used for health data collection, analysis, and reporting.
    Updates Periodically updated to reflect advances in medical knowledge and changing health trends.
    Latest Version ICD-11 became effective in January 2022.
    Uses Clinical diagnosis, health record documentation, research, health policy, and resource allocation.

    India’s quest to update ICD-11

    • Universal Language: The ICD provides a universal language that enables healthcare professionals worldwide to share standardized information.
    • Traditional Medicine Module: The 11th revision includes a module dedicated to traditional medicine conditions, offering a standardized way to collect and report data on these conditions internationally.
    • Formal Recognition: Ayurveda and related Indian traditional healthcare systems are formally recognized and widely practised in India, making a strong case for their inclusion.
    • Chinese Medicine Inclusion: After a decade of consultations, ICD-11 included Module-1, covering traditional medicine conditions originating in ancient China.

  • Centre launches Green Credit Program (GCP)

    Green Credit Program (GCP)

    Central Idea

    • The Centre has introduced a Green Credit Program (GCP) that allows individuals and entities to earn Green Credits, which can be traded on a dedicated exchange.

    What is the Green Credit Program (GCP)?

    • Objective: Aims to establish a competitive, market-based approach encouraging diverse stakeholders to undertake environmental actions.
    • Nodal Agency: Ministry of Environment, Forest, and Climate Change.

    Mechanics of Green Credit

    • Voluntary Participation: Reflects inclusivity, as engagement in the program is entirely voluntary.
    • Entities: The program extends to a diverse range of entities, encompassing individuals, industries, farmer producer organizations (FPOs), urban local bodies (ULBs), gram panchayats, and private sectors.
    • Tradability: Tradable, fostering participation in a proposed domestic market platform.
    • Certificates: Upon approval, applicants receive Green Credit certificates.

    Covered Activities

    • Qualifying Activities: The program includes various activities such as tree plantation, water conservation, sustainable agriculture, waste management, air pollution reduction, mangrove conservation, eco-mark initiatives, sustainable building, and infrastructure development.
    • Registration and Verification: Participants must register their activities on the program’s website, which will undergo verification by a designated agency.

    How are Green Credits computed?

    • Equitable Calculation: Green Credits are determined based on resource equivalence, scalability, scope, size, and other relevant parameters, aiming to achieve desired environmental outcomes.
    • Credit Registry: A dedicated Green Credit Registry will oversee the tracking and management of these credits.
    • Trading Platform: An administrator will establish and maintain a trading platform for the exchange of Green Credits within the domestic market.

    Alignment with Legal Obligations

    • Non-Tradable for Legal Compliance: Green Credits obtained for legal compliance purposes will not be tradable, ensuring adherence to existing laws.
    • Independent from Carbon Credit Scheme: The GCP operates separately from the Carbon Credit Trading Scheme, 2023, established under the Energy Conservation Act, 2001.
    • Additional Climate Benefits: Activities generating Green Credits may also yield climate-related advantages, such as carbon emissions reduction, potentially resulting in the acquisition of carbon credits.

  • CAR-T Cell Therapy approved for Cancer

    car-t

    Central Idea

    • The Drug Controller General of India (DCGI) has granted market authorization to CAR-T (Chimeric Antigen Receptor-T) cell therapy, a groundbreaking cancer treatment developed by ImmunoACT, an IIT-Bombay spin-off.
    • This authorization paves the way for its commercial introduction in India.

    About CAR-T Cell Therapy

    What is it?
    • CAR-T cell therapy stands for chimeric antigen receptor T cell therapy.
    • It is a type of cancer immunotherapy that uses the patient’s own T cells, genetically modified in a laboratory to enhance their ability to locate and destroy cancer cells.

    How does it work?
    • T cells are white blood cells responsible for identifying and fighting illness and infection.
    • Each T cell has a receptor that can recognize antigens (proteins or molecules recognized by the immune system).
    • Cancer cells may have antigens that the immune system does not recognize as abnormal, allowing cancer to evade the immune response.
    • CAR-T cells are genetically engineered in the lab to express a new receptor that can bind to cancer cells and effectively kill them.

    Therapy Process

    		 The process involves several steps, including:

    1. Collecting T Cells: Blood is drawn from the patient’s arm, and T cells are separated from the blood using an apheresis machine.

    2. Engineering T Cells: In a laboratory, the T cells are modified by adding a manufactured CAR, and they are allowed to multiply and grow.

    3. Infusing CAR-T Cells: Once enough CAR-T cells are prepared, they are injected back into the patient’s arm.

    • Chemotherapy may be recommended before CAR-T cell infusion to enhance treatment effectiveness.
    • The process can take place in an outpatient infusion center or a hospital setting.

    Cancers Treated
    • CAR-T cell therapy is effective against certain types of cancer, especially when other treatments are ineffective.
    • It is currently FDA-approved for treating haematological malignancies, including leukemia, lymphoma, and multiple myeloma.

  • Diverse Epigenetic Epidemiology Partnership (DEEP)

    Central Idea

    • CSIR-Centre for Cellular and Molecular Biology (CCMB) is spearheading a groundbreaking research endeavour called the “Diverse Epigenetic Epidemiology Partnership (DEEP)”.
    • This integrated genomics and epigenomics study aims to unravel the genetic underpinnings of NCD’s prevalent in diverse populations, including South Asians.

    Diverse Epigenetic Epidemiology Partnership (DEEP)

    • DEEP is an integrated genomics and epigenomics study focused on understanding the genetic factors behind Non-Communicable Diseases (NCDs) in diverse populations, including South Asians.
    • The project spans five years.
    • It aims to uncover the impact of genomic and environmental diversity on disease risk observed in people worldwide, including those in Asia, Africa, North America, and South America.
    • It will study individuals from various genetic and environmental contexts to identify DNA methylation patterns contributing to disease risk in each context.
    • It will develop software, infrastructure, and conduct advanced statistical analyses to create new resources.
    • This will complement international health and genetics databases and examine trends in DNA methylation variation.

    DNA Methylation

    • DNA methylation is a process in which chemical groups attach to DNA, regulating the activation and deactivation of genes.
    • This epigenetic modification helps the body respond to environmental signals and contributes to overall health and disease status.
    • Understanding the relationships between DNA methylation, genetics, and the environment is crucial for comprehending the pathways governing health, disease, and their consequences.

    Significance of this initiative

    • This research will enable the identification of disease-causing mechanisms that are common worldwide and those which are unique to particular groups or regions.
    • It will help with answering questions such as whether medicines developed in one part of the world will be effective for all.
    • Ultimately the DEEP study hopes to enable targeted interventions or treatments and reduce global health disparity and inequity.

  • Abortion Rights in India: Legal Complexities and Ethical Dilemmas

    abortion

    Central Idea

    • CJI DY Chandrachud said that India’s abortion law was liberal, pro-choice and far ahead of other countries.
    • SC is hearing the case of a married woman who wants to medically terminate her 26-week pregnancy.
    • This raises critical questions about a woman’s autonomy in deciding to abort and the existing legislative framework.

    Woman’s Perspective

    • Unplanned Pregnancy: A 27-year-old married woman, already a mother of two, contends that her pregnancy was unplanned.
    • Financial Strain: She argues that her family’s income is inadequate to support another child, and she is undergoing treatment for postpartum depression after her second child’s birth.

    Court Decisions and AIIMS Report

    • Initial Approval: A two-judge Bench initially allowed the termination, reasoning that an unplanned pregnancy due to contraceptive failure is akin to a forced pregnancy, permitting abortion up to 24 weeks.
    • AIIMS Concern: AIIMS, Delhi, raised questions about whether foeticide (stopping the foetal heart) could be performed before termination since the foetus is currently viable.
    • Three-Judge Bench: The case was transferred to a three-judge Bench, led by Chief Justice of India (CJI) D Y Chandrachud, which called for a fresh medical report to assess the foetus’s health and the woman’s medical condition.

    Understanding the Abortion Law

    • Medical Termination of Pregnancy Act (MTP Act): The MTP Act allows termination of pregnancy in three stages.
      1. Termination up to 20 weeks with the advice of one doctor.
      2. Pregnancy at 20-24 weeks requires the opinion of two registered medical practitioners, under specific conditions.
      3. After 24 weeks, a medical board in approved facilities assesses the termination based on substantial foetal abnormalities.

    Court’s History of Allowing Late-Term Abortion

    • Several Precedents: The court has previously permitted terminations beyond 26 weeks in various cases, often in cases of rape or consensual relationships.
    • Marital Status Factor: The current case distinguishes itself by the woman’s marital status, implying that the conception is consensual and not a forced pregnancy.

    Balancing Rights: Woman vs. Unborn Child

    • Ongoing Debate: The CJI-led Bench oscillates between prioritizing a woman’s rights over abortion and the need to balance the rights of the unborn child.
    • Liberal Approach: India’s law on abortion is considered liberal and pro-choice, with courts often favouring the woman’s autonomy.

    Comparisons with International Standards

    • Foetal Viability: The concept of “foetal viability” as a benchmark for abortion approval is relatively new in India. It aligns with international standards.
    • US Roe v Wade: The landmark 1973 US Supreme Court case, Roe v Wade, allowed abortion until foetal viability. In 1973, viability was at 28 weeks, now lower due to scientific advancements.
    • Criticism of Indian Law: Some critics argue that India’s law lacks clarity as the decision to terminate after 20 weeks falls on doctors rather than the women, leading to frequent court interventions.

    Autonomy vs. Unborn Child’s Rights

    • Legislative Gap: While the Indian legal framework supports a woman’s autonomy in reproductive decisions, gaps persist, especially concerning last-minute interventions.
    • Ethical Debate: The Indian law leans toward women’s autonomy, but ethical dilemmas arise regarding the rights of the unborn child.
    • Legal Precedents: Cases like Nand Kishore Sharma versus Union of India have debated the constitutionality of the MTP Act concerning the right to life of an unborn child.

    Conclusion

    • The ongoing Supreme Court case highlights the intricate legal and ethical considerations surrounding abortion in India.
    • While the law supports a woman’s right to choose, the challenge lies in finding a delicate balance between individual autonomy and the rights of the unborn child.
    • As the court grapples with this complex case, it underscores the need for continued legal discourse and potential legislative amendments to address evolving reproductive rights issues.

  • No restriction on Laptop Imports: Centre

    Central Idea

    • In August, the centre announced its intention to subject laptops, tablets, computers, and related products to a licensing regime starting from November 1.
    • However, it has now clarified that India will not impose licensing requirements on laptop and computer imports but will instead monitor their inbound shipments.

    Lapop Import Restrictions: A Backgrounder

    • Import Restrictions: In August, India imposed import restrictions on various IT hardware products to promote domestic manufacturing and reduce imports, particularly from countries like China.
    • Industry Concerns: The IT hardware industry expressed concerns following the initial licensing announcement.
    • Security and Domestic Manufacturing: The government cited security concerns and the desire to stimulate domestic manufacturing as the reasons for the licensing conditions.

    Import Statistics

    • Import Values: India imports approximately $7-8 billion worth of IT hardware products annually.
    • Recent Trends: Import values for personal computers, including laptops, decreased from $7.37 billion in 2021-22 to $5.33 billion in 2022-23. Imports of certain data processing machines also saw a decline.
    • Production-Linked Incentive Scheme: In May, the government approved the Production Linked Incentive Scheme 2.0 for IT Hardware with a budgetary outlay of ₹17,000 crore. A similar scheme for IT hardware was approved in February 2021.

    India’s Dependency on China

    • Critical Dependency: According to a report by the Global Trade Research Initiative (GTRI), India has significant dependency on China for various products, including laptops and mobile phones.
    • Government Initiatives: To reduce this dependency, the government has introduced measures such as the production-linked incentive scheme and increased customs duties on electronic components.

    Conclusion

    • India’s decision to shift from a licensing regime to monitoring for laptop and computer imports aims to balance its goals of reducing import dependency and promoting domestic manufacturing.
    • However, there is a need to ensure smoother transition for businesses and trade.

  • Large Ozone Hole detected over Antarctica

    ozone

    Central Idea

    • Satellite measurements conducted over Antarctica have unveiled a gigantic hole in the ozone layer.
    • Termed an “ozone-depleted area,” this region spans 26 million square kilometers (10 million square miles), approximately three times the size of Brazil.

    Ozone Layer and Ozone Hole

    Location Stratosphere, approximately 10-30 km above Earth’s surface.
    Composition Composed of ozone (O3) molecules.

    Unit of measurement: Dobsob Unit (DU)
    Function Acts as a protective shield, absorbing and blocking a significant portion of harmful ultraviolet (UV) radiation from the sun.
    Importance Essential for protecting life on Earth by preventing excessive UV radiation, which can harm living organisms and the environment.
    Ozone-depleting Substances Threatened by ODS like chlorofluorocarbons (CFCs), halons, and other synthetic compounds commonly used in refrigeration, air conditioning, and aerosol propellants.
    Montreal Protocol An international treaty adopted in 1987 to phase out the production and consumption of ODS, resulting in significant recovery of the ozone layer.
    Current Status The ozone layer is in the process of recovery due to the success of the Montreal Protocol.
    Environmental Impact Protects ecosystems, prevents skin cancer, cataracts, and other health issues in humans.
    Additional Facts • The size of the ozone hole over Antarctica varies annually, opening in August and closing in November or December.

    • Special winds caused by the Earth’s rotation create a unique climate over Antarctica, preventing mixing with surrounding air.

    • When these winds subside, the hole closes.

    Potential Causes of the Giant Ozone Hole

    • Volcanic Eruption in Tonga: Scientists speculate that the extensive ozone hole this year may be linked to volcanic eruptions in Hunga Tonga, Tonga, between December 2022 and January 2023. These eruptions released water vapor and other elements into the stratosphere, impacting the ozone layer through chemical reactions.
    • Human-Induced Ozone Holes: In the 1970s, scientists discovered that human activities, primarily the use of chlorofluorocarbons (CFCs), led to significant ozone depletion. These chemicals released chlorine in the stratosphere, depleting the ozone layer.
    • Effective Mitigation: The Montreal Protocol, established in 1987, aimed to combat ozone depletion by phasing out ozone-depleting substances. This international agreement successfully reduced the size of ozone holes over the years.

    Ozone Depletion and Climate Change

    • Not a Primary Climate Change Cause: Ozone depletion is not a leading contributor to global climate change.
    • Impact of Rising Temperatures: However, rising global temperatures may influence ozone holes. Extreme fires, such as those in southeastern Australia in 2020 and 2021, injected smoke into the stratosphere, potentially contributing to ozone depletion.
    • Changing Seasons: Ozone holes can alter the progression of seasons, as they extend the duration of polar vortexes, thereby extending winter periods.