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In news: Hematopoietic Stem Cell Transplantations (HSCT)


From UPSC perspective, the following things are important :

Prelims level: Umbilical Cord Blood, Hematopoietic Stem Cell Transplantations (HSCT)

Mains level: Read the attached story

stem cell

Central Idea: A celebrity couple publicly announced that they had chosen to preserve her baby’s cord blood just a few days before her baby girl was born.

What is Hematopoietic Stem Cell Transplantation (HSCT)?

  • What is it? : HSCT is a medical procedure used to treat various disorders affecting the blood, immune system, and metabolism.
  • Source of Hematopoietic Stem Cells: Hematopoietic stem cells, which have the ability to develop into different blood cell types, can be obtained from sources such as bone marrow, peripheral blood, or umbilical cord blood.
  • Autologous, Allogeneic, and Haploidentical Transplantation: HSCT can involve the use of the patient’s own stored cord blood (autologous), stem cells from a compatible donor (allogeneic), or partially matched stem cells from a family member (haploidentical).
  • Procedure Steps: HSCT involves the destruction or suppression of the patient’s abnormal or deficient hematopoietic cells, followed by the infusion of healthy stem cells.
  • Commonly Treated Conditions: HSCT is commonly used to treat conditions such as leukemia, lymphoma, aplastic anemia, inherited immune system disorders, and metabolic disorders.

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