Genetically Modified (GM) crops – cotton, mustards, etc.

Researchers found gene regulating Nitrogen absorption in Plant


From UPSC perspective, the following things are important :

Prelims level: MADS27

Mains level: Not Much

Researchers led by those from the National Centre of Biological Sciences, Tata Institute of Fundamental Research, Bengaluru (NCBS-TIFR), have found a new pathway that regulates nitrate absorption in plants.

Nitrogen in plant nutrition

  • Nitrogen is one of the most important macronutrients needed for development of a plant.
  • It is a part of chlorophyll, amino acids and nucleic acids, among others.
  • It is mostly sourced from the soil where it is mainly absorbed in the form of nitrates and ammonium by the roots.
  • Nitrates also play a role in controlling genome-wide gene expression that in turn regulates root system architecture, flowering time, leaf development, etc.
  • Thus, while a lot of action takes place in the roots to absorb and convert nitrogen into useful nitrates, the absorbed nitrates in turn regulate plant development apart from being useful as a macronutrient.

What is MADS27?

  • The gene MADS27, which regulates nitrate absorption, root development and stress tolerance, is activated by the micro-RNA, miR444, therefore offers a way to control these properties of the plant.
  • The researchers studied this mechanism in both rice (monocot) and tobacco (dicot) plants.

Regulatory switches

  • In addition to this route, several gene regulatory switches that regulate nitrate absorption and root development, such as the micro-RNA, miR444, are known in monocot plants, such as rice.
  • The micro-RNA ‘miR444’ is specific to monocots.
  • When this is not made, its target, MADS27, is produced in higher abundance, and it improves biosynthesis and transport of the hormone auxin, which is key for root development and its branching.
  • This regulatory miR444 switch is known to turn off at least five genes called MADS box transcription factor genes.
  • The speciality of the MADS box transcription factors is that they function like switch boxes of their own.
  • They bind to their favourite specific DNA sequences and they switch the neighbouring genes “on.”

Why is the discovery important?

  • Presence of nitrates is important for the plant development and also for grain production.
  • However, the overuse of nitrates in fertilizers, for instance, can lead to the dumping of nitrates in the soil which leads to accumulation of nitrates in water and soil.
  • This accumulation adds to soil and water pollution and increased contribution to greenhouse gases.
  • Also, since the whole process of nitrate absorption takes place in the roots, a well-developed root system is needed for this to take place optimally.
  • At one level, it is known that the hormone auxin is responsible for well-developed roots across all plants.
  • A number of genes are known to help with auxin production, improved nitrate transport and assimilation in plants.

Significance of MADS27

  • The MADS27 transcription factor has a three-pronged effect on the plant.
  • First, it regulates nitrate absorption by switching “on” proteins involved in this process.
  • Second, it leads to better development of the roots by regulating auxin hormone production and transport.
  • Finally, and somewhat surprisingly to the researchers, it helps in the abiotic stress tolerance by keeping the main stress player proteins “on.”



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