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Subject: Basic Sciences

  • ‘Kamala’ and ‘Pusa DST Rice 1’ GM Rice

    Why in the News?

    India’s Agriculture Minister has introduced ‘Kamala’ and ‘Pusa DST Rice 1’, the country’s first genome-edited rice varieties, developed by ICAR. These are also the world’s first genome-edited rice varieties.

    About ‘Kamala’ and ‘Pusa DST Rice 1’:

    • Kamala (DRR Dhan 100): Developed by ICAR-IIRR Hyderabad, derived from Samba Mahsuri; shows higher yield, early maturity, drought tolerance.
    • Pusa DST Rice 1: Developed by ICAR-IARI Delhi, based on MTU1010; improves drought and salinity tolerance.
    • Agencies involved: Indian Council of Agricultural Research (ICAR), ICAR-IIRR, ICAR-IARI.
    • They were created using CRISPR-Cas9-based genome editing, specifically Site Directed Nuclease 1 (SDN1). It has NO foreign DNA inserted.
    • It has been approved by Institutional Biosafety Committees (IBC) and Review Committee on Genetic Manipulation (RCGM) under relaxed genome-edit rules.

    Specific Benefits Offered:

    • Yield boost:
      • Kamala: +19% over Samba Mahsuri (avg. 5.37 t/ha, max. up to 9 t/ha).
      • Pusa DST Rice 1: +9.6% to +30.4% over MTU1010 under stress conditions.
    • Climate resilience:
      • Kamala: Drought tolerance, early maturity.
      • Pusa DST: Salt and drought tolerance for saline/alkaline/coastal soils.
    • Water saving: Kamala matures 20 days early → saves 3 irrigations, i.e., 7,500 million m³ water.
    • Emission reduction: Cultivation over 5 million ha may reduce 32,000 tonnes GHG emissions (20% drop).
    • Food security support: Improved paddy output enhances India’s average yield, critical for 40% of total foodgrain basket.
    [UPSC 2018] With reference to the Genetically Modified mustard (GM mustard) developed in India, consider the following statements:

    1. GM mustard has the genes of a soil bacterium that give the plant the property of pest-resistance to a wide variety of pests.

    2.GM mustard has the genes that allow the plant cross-pollination and hybridization.

    3.GM mustard has been developed jointly by the IARI and Punjab Agricultural University.

    Which of the statements given above is/are correct?

    Options: (a) 1 and 3 only (b) 2 only* (c) 2 and 3 only (d) 1, 2 and 3

     

  • ITER Tokamak Reactor

    Why in the News?

    Scientists working on the world’s largest nuclear fusion project ITER has completed its main magnet system with India playing a key role in building critical infrastructure.

    About ITER (International Thermonuclear Experimental Reactor):

    • ITER is the world’s largest nuclear fusion research project, aimed at demonstrating that nuclear fusion can be a safe, carbon-free, and sustainable energy source.
    • It involves 35 nations, including the EU, US, China, India, Japan, South Korea, and Russia.
    • It uses deuterium and tritium (hydrogen isotopes) to undergo fusion at temperatures over 150 million °C, 10 times hotter than the sun’s core, producing large amounts of energy.
    • Its goal is to achieve a fusion gain (Q) of 10, producing 500 megawatts of fusion power from just 50 megawatts of input heating power, a 10x gain.
    • Launched in 1985 and officially founded in 2006, the project began construction in 2007 and is expected to start its operations in 2033.
    • The tokamak is a doughnut-shaped magnetic fusion device used to contain the hot plasma required for nuclear fusion.
    • It uses powerful superconducting magnets to confine plasma and prevent it from touching the reactor walls.

    India’s Role in ITER/Tokamak:

    • India has been a full partner in ITER since 2005, contributing expertise and technology to key aspects of the project.
    • It has designed and manufactured the cryostat, a 30-meter-high, 30-meter-diameter vacuum shell made of stainless steel that houses the ITER tokamak and maintains the ultra-cold environment needed for superconducting magnets.
    • It has developed in-wall shielding to protect ITER’s components from heat generated during fusion reactions.
    • It provides cryogenic systems to cool the superconducting magnets and RF heating systems to heat the plasma to fusion temperatures.
    • It has contributed to developing the superconducting magnets, which are essential for plasma confinement inside the tokamak.

    Note:

    • India manages ITER-India, a project under the Institute for Plasma Research (IPR), overseeing key contributions, including diagnostics, power supplies, and other infrastructure.
    • It is also working on the development of a tritium breeding module for future fusion reactors, ensuring self-sufficiency in this critical fuel.

     

    [UPSC 2016] India is an important member of the ‘International Thermonuclear Experimental Reactor’. If this experiment succeeds, what is the immediate advantage for India?

    Options: (a) It can use thorium in place of uranium for power generation (b) It attain a global role in satellite-navigation (c) It can drastically improve the efficiency of its fission reactors in power generation (d) It can build fusion reactors for power generation*

     

  • New RNA-Based Approach to Combat Plant Viruses

    Why in the News?

    Recently, a team of scientists from Germany reported a breakthrough in combating the cucumber mosaic virus (CMV) through an innovative RNA-based antiviral agent.

    About Cucumber Mosaic Virus (CMV):

    • CMV is one of the most widespread and destructive plant viruses, affecting over 1,200 plant species, including important food crops such as cucumbers, melons, and cereals.
    • The virus is transmitted by aphids, tiny insects that spread the virus as they feed on plants, making outbreaks difficult to control.
    • In India, CMV causes significant yield losses in crops like bananas, pumpkins, and cucumbers, leading to mosaic discoloration, stunted growth, and unviable fruits.
    • The economic impact of CMV includes both direct financial losses from reduced crop yields and the indirect costs of pest management.

    RNA Silencing Methods discussed (HIGS vs SIGS): 

    RNA silencing is a natural defense mechanism that plants use to protect themselves from viral infections.

    Two RNA-based technologies, Host-Induced Gene Silencing (HIGS) and Spray-Induced Gene Silencing (SIGS), have been developed to enhance plant immunity against diseases like CMV.

    [1] Host-Induced Gene Silencing (HIGS):

    • HIGS involves genetically modifying plants to produce dsRNA, which activates the plant’s immune system to fight off the virus.
    • This method provides continuous protection and long-term immunity throughout the plant’s lifecycle.
    • However, it faces challenges such as regulatory issues, high production costs, and the potential for viruses to evolve resistance over time.

    [2] Spray-Induced Gene Silencing (SIGS):

    • SIGS, unlike HIGS, does not require genetic modification. Instead, plants are treated with RNA sprays containing dsRNA that targets specific viruses.
    • This method is cost-effective, non-GMO, and can be applied to a variety of crops.
    • However, SIGS provides short-term protection, may be ineffective due to random RNA mixtures, and its effectiveness can be reduced by environmental factors such as sunlight, rain, and soil microbes.
    [UPSC 2019] RNA interference (RNAi)’ technology has gained popularity in the last few years. Why?

    1. It is used in developing gene silencing therapies.

    2. It can be used in developing therapies for-the treatment of cancer.

    3. It can be used to develop hormone replacement therapies.

    4. It can be used to produce crop plants that are resistant to viral pathogens.

    Select the correct answer using the code given below:

    Options: (a) 1, 2 and 4* (b) 2 and 3 (c) 1 and 3 (d) 1 and 4 only

     

  • Role of Lipids in Protein Function and Co-Evolution

    Why in the News?

    New research by CSIR-Centre for Cellular and Molecular Biology, Hyderabad suggest that lipids (along with DNA), particularly in mitochondrial membranes, are not just structural elements but play an integral role in the function and evolution of proteins.

    About Lipids and RC1 in Cells:

    Lipids:

    • Lipids, including fats, phospholipids, and sterols, make up to 30% of the dry weight of cells.
    • They are crucial for membrane integrity and various biological processes.
    • They vary in fatty acid composition and length, influenced by genetics, diet, and environmental factors.
    • They form a bilayer in membranes, with hydrophilic heads facing outward and hydrophobic tails inward, providing stability and enabling protein function.
    • Role of Lipids in Cells:
      • Lipids form the bilayer, providing flexibility and stability for membrane proteins that perform functions like receptor binding and ion channelling.
      • They like cardiolipin stabilize RC1 and other respiratory complexes, aiding energy production.

    RC1 (Respiratory Complex 1):

    • RC1 is a protein complex in the mitochondrial membrane, crucial for cellular respiration and energy production.
    • It is composed of 44 proteins, some synthesized in the cytoplasm and others in mitochondria.
    • Mutations in RC1 lead to diseases due to its vital role in respiration.

    Lipid-Protein Co-evolution as per new Research:

    • New research highlights the co-evolution of proteins and lipids, especially in mitochondrial membranes, where proteins interact with specific lipids from their own kingdom (plant or animal).
    • Plant lipids, richer in polyunsaturated fatty acids, are more flexible, aiding stress resistance, while animal lipids evolve differently to meet their needs.
    • Lipid-protein co-evolution adds complexity to cellular evolution, with implications for human health and disease treatment.
    [UPSC 2001] Which of the following cell organelles play the most significant role in protein synthesis?

    Options: (a) Lysosome and Centrosome (b) Endoplasmic reticulum and Ribosome* (c) Golgi apparatus and Mitochondria (d) Lysosome and Mitochondria

     

  • Recycling Perovskite Solar Cells

    Why in the News?

    Recent advancements in recycling perovskite solar cells have led to a new water-based solution, offering a more sustainable and efficient approach to solar energy production.

    About Perovskite Solar Cells:

    • Perovskite solar cells are made using a perovskite crystal structure, offering high power conversion efficiencies and low manufacturing costs compared to traditional silicon-based panels.
    • They are lightweight, flexible, and made from inexpensive materials, making them a promising alternative in the solar energy market.
    • While efficient, they have a shorter lifespan and contain toxic materials like lead, posing environmental risks during disposal.
    • Used in solar power generation, electric vehicles, and energy storage systems due to their affordability and performance.

    The New Recycling Method:

    • Researchers have developed a water-based recycling solution, replacing harmful organic solvents with a non-toxic approach.
    • The process uses three salts: sodium acetate, sodium iodide, and hypophosphorous acid, to dissolve and regenerate perovskite crystals, recovering high-quality material for reuse.
    • This method maintains nearly the same efficiency as fresh materials, even after five rounds of recycling, recovering 99% of the layers.
    • It promotes a circular economy, reducing waste and supporting the environmentally friendly recycling of perovskite solar cells.
    [UPSC 2014] With reference to technologies for solar power production, consider the following statements:

    1. ‘Photovoltaics’ is a technology that generates electricity by direction conversion of light into electricity, while ‘Solar Thermal’ is a technology that utilizes the Sun’s rays to generate heat which is further used in electricity generation process.

    2. Photovoltaics generate Alternating Current (AC), while solar Thermal generates Direct Current (DC).

    3. India has manufacturing base for Solar Thermal technology, but not for Photovoltaics.

    Which of the statement(s) given above is/are correct?

    Options:

    (a) 1 only* (b) 2 and 3 only (c) 1, 2 and 3 (d) None

     

  • India’s first-ever Seed Germination Database

    Why in the News?

    On April 16, 2025, the Ecological Restoration Alliance-India (ERA-I) has released a first-of-its-kind seed germination database aimed at enhancing the success of growing native plants for ecological restoration.

    About the Seed Germination Database:

    • It was launched by the Ecological Restoration Alliance-India (ERA-I).  ERA was formed in July 2021, as an informal collective between practitioners, ecologists and individuals.
    • ERA-I collaborated with organizations like Auroville Botanical Gardens, NCF, and Wildlife Trust of India.
    • It features over 1,000 germination techniques for 465 native plant species found across India.
    • It aims to help restoration practitioners, nursery managers, and native plant enthusiasts improve success rates in growing plants for ecological restoration.
    • It is a free-access database and offers valuable information on germinating native plants crucial for restoration projects.
    • Native Plants Included:
      • The database features a diverse array of native plant species. These species are key to restoring balance in degraded ecosystems.
      • They are – Aegle marmelos (Wood apple), Bauhinia racemosa (Beedi leaf tree), Ficus benghalensis (Banyan), Withania somnifera (Ashwagandha), Ziziphus mauritiana (Indian jujube), Knema attenuata (Wild nutmeg), Lawsonia inermis (Henna), Madhuca longifolia (Mahua), Vachellia nilotica (Babool).

    Significance:

    • Native plants are essential for creating climate-resilient ecosystems.
    • Such database plays a vital role in ecological restoration.
    • It provides 1,000+ techniques for growing native plants, enhancing the success of restoration projects.
    • The database supports India’s Bonn Challenge commitment to restore 26 million hectares of degraded land by 2030.
    [UPSC 2016] In the context of food and nutritional security of India, enhancing the ‘Seed Replacement Rates’ of various crops helps in achieving the food production targets of the future. But what is/are the constraint/constraints in its wider/greater implementation?

    1. There is no National Seeds Policy in place.

    2. There is no participation of private sector seed companies in the supply of quality seeds of vegetables and planting materials of horticultural crops.

    3. There is a demand-supply gap regarding quality seeds in case of low value and high volume crops. Select the correct answer using the code given below:

    Options: (a) 1 and 2 only (b) 3 only * (c) 2 and 3 only (d) None of the above

     

  • China halts export of Rare Earth Magnets

    Why in the News?

    China has suspended exports of a wide range of critical minerals and magnets after US’s tariff embargo.

    What Are Rare Earth Elements (REEs) and RE Magnets?

    • REEs are a group of 17 elements in the periodic table, including Lanthanum (La), Neodymium (Nd), Europium (Eu), and Ytterbium (Yb).
    • Though not rare, they are found in low concentrations, making extraction challenging and costly.
    • Classification:
      • Light REEs (LREEs): Elements 57-63, such as La, Ce, Nd, and Sm.
      • Heavy REEs (HREEs): Elements 64-71, like Gd, Tb, Dy, and Er.
      • Scandium and Yttrium: Classified with HREEs due to similar chemical properties.
    • Rare Earth Magnets are powerful permanent magnets made from elements like Neodymium (Nd), Samarium (Sm), and Dysprosium (Dy).
    • They are far stronger and more efficient than traditional magnets, crucial for high-tech electronic applications.

    Global Supply Chain of REEs:

    • REEs are abundant but difficult to extract economically.
    • China alone dominates, producing 70% of the global supply and controlling 80% of the refining capacity. REEs are primarily mined from China’s Bayan Obo mine.
    • Australia, USA, Brazil, and Russia also contribute, though less significantly.
    • Refining also is largely controlled by China, though other nations are working to build their own refining capabilities to reduce dependency.
    [UPSC 2022] Consider the following statements:

    1. Monazite is a source of rare earths. 2. Monazite contains thorium. 3. Monazite occurs naturally in the entire Indian coastal sands in India. 4. In India, Government bodies only can process or export monazite.

    Which of the statements given above are correct?

    (a) 1, 2 and 3 only (b) 1, 2 and 4 only* (c) 3 and 4 only (d) 1, 2, 3 and 4

     

  • KATRIN Experiment

    Why in the News?

    The KATRIN (Karlsruhe Tritium Neutrino Experiment) has made a groundbreaking achievement by measuring neutrino mass with a new precision.

    About the KATRIN Experiment:

    • The KATRIN is located at the Karlsruhe Institute of Technology (KIT), specifically on its Campus North site in Karlsruhe, Germany.
    • It is aimed at measuring the mass of the electron antineutrino with sub-eV precision.
    • It has measured the mass of neutrinos by studying the beta decay of tritium, a radioactive form of hydrogen.
    • The mass was inferred by analyzing the energy of the emitted electrons.
    • Technological Setup:
      • A 70-meter-long beamline with a powerful tritium source.
      • A 10-meter-wide spectrometer to measure the energy of emitted electrons with high precision.
    • Key Findings:
      • KATRIN has set a new upper limit for neutrino mass at less than 0.45 eV/c² (8 × 10⁻³⁷ kg), nearly twice as precise as previous measurements from 2022.
      • Data Collection was based on five campaigns from 2019-2021, totalling 250 days of data.

    Neutrinos and Their Properties

    • Neutrinos are extremely light subatomic particles that rarely interact with matter, making them difficult to detect.
    • They are found in cosmic rays and solar radiation.
    • Properties:
      • Mass: Their small mass influences cosmic structure formation, such as galaxies and clusters.
      • Weak Interaction: They interact via the weak nuclear force, allowing them to pass through vast amounts of matter.
    • They are essential in particle reactions and play a key role in galaxy formation and the study of dark matter.

     

    [UPSC 2010] India-based Neutrino Observatory is included by the planning commission as a mega-science project under the 11th Five-year plan. In this context, consider the following statements:

    1.Neutrinos are chargeless elementary particles that travel close to the speed of light.

    2.Neutrinos are created in nuclear reactions of beta decay.

    3.Neutrinos have a negligible, but non-zero mass.

    4.Trillions of Neutrinos pass through the human body every second.

    Which of the statements given above are correct?

    (a) 1 and 3 only  (b) 1, 2 and 3 only  (c) 2, 3 and 4 (d) 1, 2, 3 and 4

     

  • Novel Silicon Photonics Breakthrough

    Why in the News?

    In a major breakthrough, Indian researchers have developed a new type of laser that can be placed directly onto silicon chips, a key component of modern computers.

    What is Silicon Photonics?

    • Silicon photonics is a technology that uses light (photons) instead of electrical signals to transmit data inside computer systems.
    • Light can carry more data at higher speeds with less energy than electricity, making it a promising technology for future computing and data transfer.
    • Traditional silicon chips struggle to produce light, requiring external lasers, which were inefficient and costly.
    • Silicon photonics can significantly enhance data transfer speed and efficiency, benefiting industries like data centers and telecommunications.

    About the Miniaturized Laser Technology

    • Indian researchers have successfully integrated a laser directly onto a silicon chip, eliminating the need for separate lasers.
    • The laser is made using gallium arsenide (where 20% of gallium atoms had been replaced with indium to achieve optimal light emission), which helps silicon emit light, a crucial step since silicon alone cannot produce light efficiently.
    • It uses minimal power, ideal for high-performance, energy-efficient computers.
    • Direct integration reduces costs, making the technology scalable for mass production.
    • This innovation boosts computing power, particularly in data centers where fast data transfer is critical.
    • Efforts are underway to enhance its durability, especially at higher temperatures, for broader industrial use.
    [UPSC 2008] Which one of the following laser types is used in a laser printer?

    (a) Dye laser (b) Gas laser (c) Semiconductor laser (d) Excimer laser

     

  • [pib] Cu-Phen Metallo-Nanozymes and its Applications

    Why in the News?

    Researchers from the CSIR-Central Leather Research Institute (CLRI), Chennai has developed a new nanozyme, Cu-Phen, using a catalyst-by-design strategy. A nanozyme is a type of synthetic enzyme made from nanomaterials (extremely tiny particles) that can mimic the function of natural enzymes in biological systems.

    About the Metallo-Nanozymes 

    • Cu-Phen (Copper-Phenylalanine) is a type of metallo-nanozyme developed by Indian researchers.
    • It is a synthetic enzyme that mimics the functions of natural enzymes in the body, particularly in controlling the flow of energy at the cellular level.
    • It is made by combining copper ions (Cu²⁺) with phenylalanine, an amino acid, using a special design method called “catalyst-by-design”.
    • It forms a self-assembled nano-structure with a well-defined active site, which is where the enzyme’s function occurs.
    • This structure helps Cu-Phen control the electron transfer process, which is important for many biological functions.
    • Unlike traditional nanozymes, which often have poorly defined active sites, Cu-Phen has a precisely structured active site, allowing it to work more efficiently like natural enzymes in the body.
    • Cu-Phen interacts with cytochrome c, a protein that plays a key role in the electron transport chain, which is part of how our body generates energy.
    • It helps reduce oxygen to water without producing harmful substances called reactive oxygen species (ROS), which can damage cells.

    Potential Applications

    • Cu-Phen could be used to make energy systems more efficient, like in bioenergy (energy from living things), by mimicking natural energy-making processes.
    • It could help treat diseases like neurodegenerative diseases and cancer by controlling energy production in cells and reducing harmful effects on the body.
    • These nanozymes can help clean water and make energy systems work better, while reducing pollution and harmful by-products.
    • Cu-Phen can also be used in factories to help make useful products like medicines and chemicals by working like artificial enzymes.
    • This new nanozyme is a step forward in creating artificial enzymes that could be used in many areas like medicine, energy, and manufacturing.
    [UPSC 2022] Consider the following statements :

    1. Other than those made by humans, nanoparticles do not exist in nature.

    2. Nanoparticles of some metallic oxides are used in the manufacture of some cosmetics.

    3. Nanoparticles of some commercial products which enter the environment are unsafe for humans.

    Which of the statements given above is/are correct ?

    (a) 1 only (b) 3 only (c) 1 and 2 (d) 2 and 3