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Subject: Science and Technology

  • Scientists discover ‘Einstein Ring’

    Why in the News?

    The European Space Agency’s (ESA) Euclid Space Telescope has captured a rare Einstein Ring around a galaxy nearly 590 million light-years away from Earth.

    Scientists discover ‘Einstein Ring’

    What is an Einstein Ring?

    • An Einstein Ring is a circular ring of light caused by gravitational lensing, a phenomenon predicted by Einstein’s General Theory of Relativity.
    • It occurs when a massive celestial object (like a galaxy) bends and magnifies light from a more distant background galaxy that lies directly behind it.
    • The recent discovery by ESA’s Euclid telescope identified an Einstein Ring around NGC 6505, located 590 million light-years away, acting as a lens for a distant galaxy 4.42 billion light-years away.
    • Features of an Einstein Ring:
      • Perfect circular shape (only if source, lens, and observer align precisely).
      • Example of strong gravitational lensing, distorting background light.
      • Extremely rare (found in less than 1% of galaxies).
      • Not visible to the naked eye, observed only with advanced space telescopes like Euclid or Hubble.

    Significance of the Discovery:

    • Reveals Dark Matter: Helps indirectly map dark matter, which makes up 85% of the universe.
    • Magnifies Hidden Galaxies: Makes faint, distant galaxies visible for study.
    • Measures Universe’s Expansion: Tracks how light stretches over time, refining cosmological models.
    • Confirms Einstein’s Theory: Proves light bends in curved space-time, supporting gravitational lensing theory.
    • Demonstrates Euclid’s Capabilities: Shows Euclid’s high-resolution potential, promising more discoveries.

    PYQ:

    [2018] Consider the following phenomena:

    1. Light is affected by gravity.
    2. The Universe is constantly expanding.
    3. Matter warps its surrounding space-time.

    Which of the above is/are the prediction/predictions of Albert Einstein’s General Theory of Relativity, often discussed in media?

    (a) 1 and 2 only
    (b) 3 only
    (c) 1 and 3 only
    (d) 1, 2 and 3

     

  • PARAS-2 Spectrograph

    Why in the News?

    Scientists at PRL, Ahmedabad, discovered the exoplanet TOI-6038A b, a dense sub-Saturn-sized planet with a mass of 78.5 Earth masses and a radius of 6.41 Earth radii, using the PARAS-2 spectrograph at Mount Abu Observatory.

    About TOI-6038A b

    • TOI-6038A b is a dense sub-Saturn-sized planet with a mass of 78.5 Earth masses and a radius of 6.41 Earth radii, orbiting a bright, metal-rich F-type star every 5.83 days in a circular orbit.
    • This is the 2nd exoplanet discovery using the PARAS-2 spectrograph.
    • It is also the 5th exoplanet detection combining efforts of PARAS-1 and PARAS-2, showcasing India’s growing expertise in astronomical instrumentation.

    About PARAS-2 Spectrograph:

    • PARAS-2 (PRL Advanced Radial-velocity All-sky Search-2) is a state-of-the-art high-resolution spectrograph designed for exoplanet detection.
    • The development of PARAS-2 began in mid-2018 and was successfully installed at the telescope site in mid-2022.
    • It is the highest-resolution stabilized radial velocity (RV) spectrograph in Asia, operating at a precision level of 30 cm/s.
    • It is installed at PRL’s 2.5-meter telescope at the Mount Abu Observatory, benefiting from high-altitude, clear sky conditions.
    • Key Features of PARAS-2:
      • Operates in the 380-690 nm waveband, making it suitable for studying a wide range of celestial objects.
      • Resolution of ~107,000, the highest in Asia, enabling ultra-precise exoplanetary studies.
      • Ultra-stable temperature and pressure environment: Maintained at 24 ± 0.001 °C and 0.005 ± 0.0005 mbar, ensuring minimal instrumental drift.
      • Uses a Uranium Argon Hollow Cathode Lamp (UAr HCL) for calibration, achieving a velocity precision of better than 2 m/s.
      • Advanced optical fiber system for capturing stellar light and spectral calibration data simultaneously.
    • It uses the radial velocity method, which detects tiny wobbles in a star’s motion caused by the gravitational pull of an orbiting planet.
    • These wobbles cause shifts in the star’s light spectrum, allowing scientists to determine a planet’s presence, mass, and orbital period.
    • It can detect minute stellar movements, making it ideal for finding low-mass exoplanets like super-Earths.

    PYQ:

    [2015] The term ‘Goldilocks Zone’ is often seen in the news in the context of:

    (a) the limits of habitable zone above the surface of the Earth
    (b) regions inside the Earth where shale gas is available
    (c) search for the Earth-like planets in outer space
    (d) search for meteorites containing precious metals

     

  • Reimei: World’s 1st Hybrid Quantum Supercomputer goes Online

    Why in the News?

    Japan has officially launched the world’s first hybrid quantum supercomputer, integrating a 20-qubit quantum processor, Reimei, into Fugaku, the world’s sixth-fastest supercomputer.

    About Reimei

    • Reimei is a 20-qubit trapped-ion quantum computer developed by Quantinuum and integrated into Fugaku, the world’s sixth-fastest supercomputer, at Riken, Japan.
    • It is the first fully operational hybrid quantum supercomputer, combining quantum and classical computing for advanced problem-solving.
    • Key Features:
      • Trapped-Ion Qubits: Unlike superconducting qubits, Reimei uses trapped-ion technology, offering higher stability, longer coherence times, and stronger qubit connectivity.
      • Hybrid Integration: Works alongside Fugaku to solve complex calculations faster than classical supercomputers.
      • Ion Shuttling: Enables physical movement of qubits, allowing for more complex quantum algorithms.
      • Error Correction: Uses logical qubits, reducing error rates 800 times lower than standard qubits.
    • Applications:
      • Physics & Chemistry Research: Used for molecular simulations, material science, and high-energy physics.
      • Quantum Cryptography & AI: Enhances cybersecurity and artificial intelligence models.
      • Optimization & Machine Learning:  Solves large-scale optimization problems.
    • Significance:
      • Bridges classical and quantum computing, serving as a transition to fully scalable quantum systems.
      • Paves the way for real-world quantum applications, accelerating scientific and technological advancements.

    PYQ:

    [2022] Which one of the following is the context in which the term “qubit” is mentioned?

    (a) Cloud Services
    (b) Quantum Computing
    (c) Visible Light Communication Technologies
    (d) Wireless Communication Technologies

     

  • [pib] Nationwide Mass Drug Administration (MDA) Campaign for Lymphatic Filariasis (LF) Elimination 

    Why in the News?

    Union Minister for Health and Family Welfare has launched the Annual Nationwide Mass Drug Administration (MDA) Campaign to eliminate Lymphatic Filariasis (LF).

    About Lymphatic Filariasis (LF):

    • Lymphatic Filariasis (LF), or “Hathi Paon”, is a mosquito-borne parasitic disease caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori.
    • It affects the lymphatic system, leading to swelling of limbs (lymphoedema) and scrotal swelling (hydrocele), causing permanent disability.
    • LF spreads through repeated mosquito bites, making it a major public health challenge in tropical regions, including India.
    • India aims to eliminate LF by 2027, ahead of the 2030 Sustainable Development Goal (SDG) target.

    What is Mass Drug Administration (MDA)?

    • MDA is a large-scale public health campaign where anti-filarial medicines are administered to all eligible individuals in endemic areas to stop LF transmission.
    • Medication Regimens:
      • Double Drug Therapy (DA): Diethylcarbamazine Citrate (DEC) + Albendazole
      • Triple Drug Therapy (IDA): Ivermectin + DEC + Albendazole
    • Key Features of MDA
      • Door-to-door supervised drug administration ensures high coverage.
      • Drugs are safe, free, and given twice a year in targeted districts.
      • MDA is crucial for eliminating LF, as it reduces parasite transmission and protects millions from disability.
    • EXCEPTIONS: Children below 2 years, pregnant women, and seriously ill individuals.

    PYQ:

    [2017] Consider the following statements:

    1. In tropical regions, Zika virus disease is transmitted by the same mosquito that transmits dengue.

    2. Sexual transmission of Zika virus disease is possible.

    Which of the statements given above is/are correct?

    (a) 1 only

    (b) 2 only

    (c) Both 1 and 2

    (d) Neither 1 nor 2

     

  • Genotype D1.1

    Why in the News?

    The US Department of Agriculture has confirmed a new spillover of H5N1 avian flu genotype D1.1 into dairy cattle in the United States.

    What is Genotype D1.1?

    • Genotype D1.1 is a strain of the H5N1 highly pathogenic avian influenza (HPAI) virus, primarily found in poultry and wild birds.
    • It is part of the H5 clade 2.3.4.4b, which has been responsible for multiple outbreaks worldwide.
    • It was recently confirmed in dairy herds in Churchill County, Nevada, USA.
    • Symptoms in Cattle: Includes fever, reduced milk production, coughing, sneezing, and nasal discharge.
    • Differences from B3.13: Genotype B3.13, the previous dominant H5N1 strain in cattle, caused milder infections in humans, whereas D1.1 has led to more severe cases.

    Bird Flu (Avian Influenza) Spillover of H5N1 Virus

    • A spillover event occurs when a virus jumps from its natural host species (wild birds) to other animals or humans.
    • It spreads through wild bird migration routes, carrying the virus across continents.
    • The virus has been detected in unpasteurized milk from infected cows, raising concerns about worker exposure.

    Impacts on India

    • Although genotype D1.1 has not been detected in India, the growing spread of H5N1 in cattle and humans abroad raises concerns for public health and livestock industries in India.
    • India is part of major bird migration routes (Central Asian Flyway & East Asian-Australasian Flyway), making it vulnerable to H5N1 spread from infected wild birds.
    • With India being the world’s largest milk producer, a spillover of H5N1 into dairy cattle could severely impact milk production and exports.
    • While human cases remain rare, a mutation allowing human-to-human transmission could lead to a pandemic-like scenario.
    •  India poultry products exports to Middle Eastern and Asian markets; an H5N1 outbreak could lead to bans and economic losses.

    PYQ:

    [2015] H1N1 virus is sometimes mentioned in the news with reference to which one of the following diseases?

    (a) AIDS

    (b) Bird flu

    (c) Dengue

    (d) Swine flu

     

  • Diagnostic sector requires Regulations

    Why in the News?

    India has around 3,00,000 diagnostic labs, and the number is increasing. However, the sector is largely unregulated, scattered, and concentrated in urban areas.

    What is the significance of India’s Diagnostics Sector?

    • Market Size and Growth: The Indian diagnostics market was valued at approximately US$13 billion in 2023 and is projected to reach US$25 billion by FY28. It is expected to grow at a CAGR of around 14%. Some projections estimate the market could reach US$40 billion by 2034.
    • Essential Component of Healthcare: Diagnostics play a crucial role in disease prevention, early detection, and effective management, making them an essential part of modern healthcare. Doctor recommendations drive a major part of the diagnostic business, with tests being conducted for most patients before prescribing medication.
    • Key Market Segments: The sector is primarily divided into pathology (60%) and radiology (40%). Pathology is further broken down into illness (acute and chronic) and wellness segments.
    • Drivers of Growth: Several factors contribute to the sector’s growth, including increasing life expectancy, a growing middle class, higher penetration of government insurance schemes, rising income levels, and increasing awareness of preventive testing. An aging population and the rise in chronic diseases also fuel the demand for diagnostic services.

    What are the challenges faced by the Diagnostics Sector?

    • Urban-Rural Divide: A significant portion of diagnostics revenue (76%) comes from urban areas, even though 70% of India’s population resides in rural areas.
    • Disparities in Infrastructure: Rural areas have fewer healthcare facilities, with only about 36.5% of the total hospital beds, leading to delayed treatments and poorer health outcomes
    • Regulatory Issues: The Kerala State Clinical Establishments Act faces resistance due to stringent space (300 sq. ft. in rural areas, 500-700 sq. ft. in urban areas) and educational requirements, making compliance unviable for many small labs.
    • Standardization Needs: Lack of uniform testing protocols leads to errors. Example: A government lab in Karnataka reported a platelet count of 0.47 lakh/cmm, but a private lab retest showed 2.2 lakh/cmm, highlighting the need for mandatory NABL accreditation and standard SOPs to ensure diagnostic accuracy.
    • Infrastructure Gaps in Public Sector: Lack of essential upgrades in government labs (e.g., Osmania and Gandhi Hospitals in Hyderabad). Limited operational hours and unavailability of specialists in government hospitals force patients to private facilities.

    What are the present Regulations implemented by the govt for this Sector?

    • Clinical Establishments Act, 2010: This act aims to regulate diagnostic centers but has been adopted by only 12 states and Union Territories, leading to inconsistent regulations across the country.  
    • Medical Devices Rules, 2017: These rules govern medical devices, an integral part of the diagnostics framework, focusing on manufacturing, import, sale, distribution, and quality and safety control. They provide risk-based categorization, establish product standards, and set timelines for obtaining licenses.
    • State-Specific Regulations: Some states like Karnataka and Kerala have separate regulatory frameworks, but enforcement remains inconsistent. Tamil Nadu’s Clinical Establishments (Regulations) Rules, 2018, mandate minimum space requirements for labs.
    • Pricing Regulations for Government-Led Diagnostic Schemes: Limits test costs to reduce out-of-pocket expenses for patients. Example: Telangana’s T-Diagnostics Programme has conducted 18.10 crore tests at subsidized rates, saving ₹1,100 crore for patients.
    • Mandatory Quality Control & External Audits: Enforces periodic inspections to maintain test accuracy. Example: Karnataka’s KPME Act mandates SOPs for sample collection, testing, and reporting, with penalties for non-compliance.

     

    Way forward: 

    • Expand Rural Diagnostic Infrastructure: Strengthen public-private partnerships (PPPs) to enhance diagnostic services in rural areas, improve affordability, and ensure equitable access through mobile labs and telemedicine integration.
    • Enforce Uniform Regulatory Standards: Implement a nationwide mandatory NABL accreditation and standard operating procedures (SOPs) for all diagnostic centers to ensure quality, accuracy, and compliance across states.

    Mains PYQ:

    Q What do you understand by nanotechnology and how is it helping in health sector? (UPSC IAS/2020)

  • Biotechnology for Economy, Environment and Employment (BioE3) Policy

    Why in the News?

    After the BioE3 Policy approval in August 2024, the Department of Biotechnology (DBT) held consultations with State governments on setting up biomanufacturing facilities across India.

    What is the BioE3 Policy?

    • It is a national initiative by the Department of Biotechnology (DBT), Ministry of Science and Technology to promote biomanufacturing and a circular bioeconomy in India.
      • Biomanufacturing involves the industrial production of bio-products such as biopolymers, enzymes, smart proteins, functional foods, precision biotherapeutics, and climate-resilient agricultural products.
    • It focuses on scaling up biotechnology-based industries, enhancing research and innovation, and creating employment opportunities in sustainable bio-based sectors.
    • It aligns with India’s Net Zero carbon commitment and aims to make biomanufacturing a key driver of economic growth.

    Objectives and Features of the BioE3 Policy

    • Promoting Biomanufacturing: Establishing biomanufacturing hubs and biofoundries to produce bio-based chemicals, polymers, and enzymes.
    • Strengthening R&D and Innovation: Encouraging state-driven biotechnology policies, bio-AI hubs, and technology-driven bioindustries.
    • State-Centric Implementation: States will adopt at least two thematic areas under BioE3, focusing on local bio-based industries and sustainable agriculture.
    • Workforce Development: Expanding biotechnology training programs in Tier-II and Tier-III cities to build a skilled workforce.
    • Biosafety and Regulatory Compliance: Ensuring adherence to global biosafety standards and responsible biotechnology innovation.
    • Carbon Capture and Sustainability: Supporting carbon sequestration technologies and climate-resilient agriculture to mitigate climate change impacts.
    • Encouraging Private Sector Investment: Creating a business-friendly environment for biotech startups, public-private partnerships, and global collaborations.

    Programs Implemented Under the BioE3 Policy:

    • State-Centric BioE3 Cells: Dedicated cells will be established in State departments to coordinate investments, research, and policy execution.
    • Precision Biotherapeutics and Functional Foods Initiative: Research into next-generation bio-based medicines, smart proteins, and functional foods.
    • Carbon Capture and Bioeconomy Models: Development of technologies for carbon sequestration and sustainable bio-based industrial processes.
    • Public-Private Partnerships: Collaboration between government, industry, and research institutions to drive biomanufacturing investments and commercialization.

    PYQ:

    [2015] With reference to bio-toilets used by the Indian Railways, consider the following statements:

    1. The decomposition of human waste in the bio-toilets is initiated by a fungal inoculum.

    2. Ammonia and water vapour are the only end products in this decomposition which are released into the atmosphere.

    Which of the statements given above is/are correct?

    (a) 1 only

    (b) 2 only

    (c) Both 1 and 2

    (d) Neither 1 nor 2

  • What is Brucellosis?

    Why in the News?

    An 8-year-old girl in Kerala, recently succumbed to brucellosis, a bacterial infection primarily caused by the consumption of unpasteurised milk.

    About Brucellosis

    • Brucellosis is a bacterial infection caused by Brucella species, primarily affecting cattle, goats, sheep, swine, and dogs.
    • Humans contract it through direct contact with infected animals, consuming contaminated animal products, or inhaling airborne agents.
    • According to the World Health Organization (WHO), the most common cause is the ingestion of unpasteurised milk or cheese from infected livestock.
    • Symptoms and Risk Factors:
      • Symptoms: Fever, weakness, weight loss, and general discomfort. The incubation period is 1-2 months, but most cases develop within 2-4 weeks.
      • At-Risk Groups: Farmers, butchers, veterinarians, hunters, and laboratory personnel handling infected animal tissues.
    • Treatment and Prevention:
      • Treatment: Doxycycline (100 mg, twice daily for 45 days) and Streptomycin (1 g daily for 15 days) as per medical advice.
      • Prevention: Vaccination of livestock, pasteurisation of milk, and public awareness campaigns to discourage the consumption of unpasteurised dairy products.

  • The financial toxicity of cancer care in India

    Why in the News?

    The financial strain of cancer is often ignored but can be the most harmful. It not only impacts the patient but also their family and future generations.

    What is the extent of financial toxicity faced by cancer patients in India?

    • High Treatment Costs: Cancer treatments, especially advanced options like immunotherapy, can be prohibitively expensive. For instance, a patient with oral cancer may face annual costs of approximately ₹10 lakh, adding to previous expenses that can total ₹25 lakh over several years. This financial strain often forces families to deplete savings or sell assets to afford care.
    • Impact on Families: Financial toxicity extends beyond the patient to their families, leading to severe economic consequences. Families may resort to selling properties or skipping meals to manage treatment costs, which can entrap them in a cycle of generational poverty.
    • Out-of-Pocket Expenses: A significant portion of healthcare costs is borne out-of-pocket by patients. For example, outpatient expenses can account for nearly 50% of total healthcare costs, which are not covered by insurance schemes like Ayushman Bharat.

    What are the contributing factors to financial toxicity in cancer care?

    • Inadequate Public Health Funding: India’s public health expenditure has historically been below 2% of GDP, resulting in insufficient healthcare infrastructure and personnel in public hospitals. This leads to delays in diagnosis and treatment, particularly for advanced cancer cases that require more costly interventions.
    • Limited Insurance Coverage: Existing insurance schemes primarily cover inpatient costs, leaving patients responsible for outpatient diagnostics and follow-up treatments. This gap significantly contributes to the financial burden on patients and their families.
    • Economic Disparities: Patients from low and middle-income backgrounds face additional hurdles in accessing cutting-edge treatments due to their high costs and limited availability in public health systems.

    What are the steps taken by the Indian Government? 

    • Health Minister’s Cancer Patient Fund (HMCPF): Established in 2009 under the Rashtriya Arogya Nidhi, this fund provides financial assistance up to ₹5 lakh for cancer treatment at designated Regional Cancer Centers (RCCs).
      • In emergency cases, assistance can go up to ₹15 lakh. The fund aims to support patients living below the poverty line.
    • Ayushman Bharat – Pradhan Mantri Jan Arogya Yojana (PM-JAY): This scheme offers health coverage of up to ₹5 lakh per family per year for secondary and tertiary care hospitalization, including cancer treatments. It is designed for low-income families and is operational across India.
    • State-Specific Schemes: Various states have their own initiatives:
      • Arogyasri Scheme in Andhra Pradesh: Provides free cancer treatment for families with an annual income below ₹5 lakh.
      • Free Chemotherapy in Odisha: Offers free chemotherapy treatment at district hospitals for poor cancer patients.
      • Financial Assistance in Punjab: Up to ₹1.5 lakh is provided for cancer treatment to eligible residents.

    What strategies can be implemented to mitigate financial toxicity? (Way forward)

    • Strengthening Public Healthcare: Increasing government investment in public health could improve access to affordable cancer care.
      • States like Delhi and Kerala have initiated schemes to support direct medical costs, but broader implementation is needed across India.
    • Supportive Measures for Non-Medical Costs: Initiatives such as discounted travel fares for cancer patients can alleviate some financial burdens associated with non-medical expenses. Expanding these programs could provide significant relief.
    • Role of Nonprofits and CSR: Nonprofit organizations play a crucial role in reducing out-of-pocket expenses through various support services. Increased funding from corporate social responsibility (CSR) initiatives could help these organisations expand their reach and impact.
    • Promoting Philanthropy: Encouraging individual philanthropy among wealthier segments of society could provide critical funding for cancer care initiatives and nonprofits focused on assisting low-income patients.
    • Policy Advocacy: Advocating for policies that address the gaps in insurance coverage and promote equitable access to cancer treatments is essential for reducing financial toxicity in the long term.

    Mains PYQ:

    Q What are the research and developmental achievements in applied biotechnology? How will these achievements help to uplift the poorer sections of the society? (UPSC IAS/2021)

  • [pib] GARBH-Ini-DRISHTI: India’s First Ferret Research Facility

    Why in the News?

    India’s first Ferret Research Facility, GARBH-Ini-DRISHTI, was inaugurated at Translational Health Science and Technology Institute (THSTI) in Faridabad to boost vaccine development and infectious disease research.

    About GARBH-INi-DRISHTI

    • GARBH-INi-DRISHTI is a data repository and information-sharing hub designed to provide comprehensive clinical and biological insights into maternal and child health.
    • Developed under the GARBH-INi program, it is one of South Asia’s largest pregnancy cohort datasets, offering access to clinical data, medical images, and bio-specimens.
    • The platform includes data from over 12,000 pregnant women, newborns, and postpartum mothers, enabling extensive research into maternal and neonatal health outcomes.
    • It is a collaborative initiative, involving India’s top research institutions and hospitals, ensuring scientific synergy in maternal healthcare.
    • Aims:
      • To enhance maternal and neonatal healthcare research through large-scale data accessibility.
      • To support global researchers in conducting transformative studies that can improve birth outcomes.
      • To provide early insights into pregnancy-related complications, fostering better diagnostic and preventive measures.
      • To develop predictive tools for conditions like preterm birth, ensuring better maternal health interventions.
    • Features:
      • Comprehensive Data Repository: Houses clinical, imaging, and bio-specimen data from thousands of pregnant women and newborns.
      • Advanced Data Access: Researchers can explore detailed datasets to study pregnancy outcomes, foetal health, and postnatal development.
      • Secure and Controlled Access:  Provides clear guidance on data usage and approvals, ensuring ethical research practices.
      • Global Research Platform: Enables nationwide and international collaboration, allowing researchers to work on common healthcare challenges.
      • Supports Policy and Decision-Making:  The data can be leveraged to shape maternal health policies, improve diagnostic protocols, and design effective interventions.