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Innovations in Biotechnology and Medical Sciences

Next Generation Nanomedicine for Breast Cancer

Why in the news?

Scientists from Agharkar Research Institute developed a biodegradable nanomedicine platform capable of silencing cancer driving genes in breast cancer cells, offering a promising precision oncology therapy.

Key Highlights

  • Research published in: Advanced Healthcare Materials.
  • Developed under: Department of Science and Technology.
  • Uses: Targeted gene silencing strategy.
  • Aim: Effective tumour inhibition with minimal toxicity.

What is Nanomedicine?

Nanomedicine refers to the use of nanoscale materials and technology for:

  • Diagnosis
  • Drug delivery
  • Treatment of diseases.

What is Precision Nanomedicine?

  • Precision nanomedicine: Targets disease causing cells specifically.
  • Reduces:
    • Damage to healthy tissues.
    • Side effects associated with conventional therapies.

Key Technology Used

Mesoporous Silica Nanoparticles

  • Biodegradable nanoparticles with:
    • High drug loading capacity.
    • Tunable surface chemistry.
  • Used to deliver: Small interfering RNA (siRNA).

What is siRNA?

  • Small interfering RNA (siRNA): Molecules that silence specific genes by preventing protein production.
  • Used in:
    • Gene therapy
    • Cancer treatment research.

[2015] With reference to the use of nanotechnology in health sector, which of the following statements is/are correct?
1.Targeted drug delivery is made possible by nanotechnology
2.Nanotechnology can largely contribute to gene therapy
Select the correct answer using the code given below.

[A] 1 only

[B] 2 only

[C] Both 1 and 2

[D] Neither 1 nor 2


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