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Subject: Science and Technology

  • Hepatitis A vaccination will be cost-effective in Kerala: study

    Why in the News? 

    • Hepatitis A infection in Kerala is shifting from early childhood to adolescents and young adults due to better sanitation and hygiene practices.
      • The inclusion of hepatitis A vaccination into the mainstream immunization program for both one-year-old children and 15-year-old individuals in Kerala shows cost-effectiveness and success.

    Present State in Kerala and Overall India:

    • At the Regional level (Kerala): Kerala has been experiencing regular hepatitis A outbreaks, with the 2024 outbreak being particularly severe.
      • As of May 30, over 2,400 cases and 18 deaths have been reported, mainly in districts like Kozhikode, Malappuram, Thrissur, and Ernakulam.
    • At the National Level: Severity in Different Age Groups: Almost 50% of children aged 1-5 years in India were found to be susceptible to the hepatitis A virus.
      • However, the hepatitis A vaccine is currently only available for those who can afford it, and is not part of the national immunization program.

    About Hepatitis A infection:

    • The infection is usually mild or asymptomatic in children under six years but can be symptomatic and severe in older children, adolescents, and adults, occasionally leading to liver injury and fatalities.
    • India has recently launched its first indigenously developed hepatitis A vaccine, called Havisure:
      • Havisure was launched in January 2024 by Indian Immunologicals Limited (IIL), a subsidiary of the National Dairy Development Board.
      • IIL plans to manufacture up to 1 million doses of Havisure per year initially, focusing on the domestic market first.
    Types of Hepatitis Cause Vaccine
    Hepatitis A (HAV) Spread through ingestion of contaminated food or water. Hepatitis A vaccine (e.g., Havrix, Vaqta)
    Hepatitis B (HBV) Spread through contact with infectious body fluids (blood, semen, etc.) Hepatitis B vaccine (e.g., Engerix-B, Recombivax HB)
    Hepatitis C (HCV)  Spread primarily through blood-to-blood contact, often via injection drug use or unsafe medical procedures. No vaccine is available currently. Treatment focuses on antiviral medications
    Hepatitis D (HDV) Requires HBV as a co-infection to cause illness. No specific vaccine for HDV. Prevention relies on hepatitis B vaccination.
    Hepatitis E (HEV) Spread through ingestion of contaminated water, similar to HAV A vaccine is available in some regions (e.g., Hecolin in China), but not widely used. Prevention mainly involves improving sanitation and safe drinking water

    Benefits of Hepatitis A Vaccination in Kerala:

    • Lifelong Immunity: Vaccination provides lifelong immunity against the hepatitis A virus, protecting individuals from severe infections and health complications later in life.
    • Less Out-of-Pocket Expenditure: Studies have shown that vaccinating children aged one year and adolescents aged 15 years in Kerala using either live attenuated or inactivated vaccines is cost-effective.
      • Vaccination prevents future healthcare expenditures associated with treating hepatitis A infections.
    • Increase in Household savings: Implementing vaccination for adolescents could save Kerala ₹5,872 million to ₹10,553 million over five years, depending on the type of vaccine used.
    • Equal and Universal Accessibility: Due to the inclusion in the universal immunization program, these vaccines are accessible throughout all sections of society, whether rich or poor.

    Government Initiatives:

    • National Viral Hepatitis Control Program (NVHCP): The Ministry of Health and Family Welfare launched the NVHCP in July 2018 to prevent and control viral hepatitis in India.
      • The program aims to combat hepatitis and achieve country-wide elimination of hepatitis C by 2030, reduce morbidity and mortality associated with hepatitis B and C, and reduce the risk, morbidity, and mortality due to hepatitis A and E.
    • State-Level Initiatives: Some states like Punjab, Assam, Manipur, Tripura, and Haryana have started free or subsidized hepatitis C treatment programs.
      • Haryana launched its own Hepatitis Control Program in 2013 at PGIMS Rohtak, which was later expanded to all district civil hospitals in the state in 2017.

    What is the Prime challenge?

    • Achieving high vaccination coverage among adolescents, who are not covered under the universal immunization program, remains a challenge. Strategies such as school-based vaccination campaigns are proposed to enhance this kind of coverage.

    Conclusion:  Implement targeted vaccination campaigns in schools and communities to ensure high coverage among adolescents aged 15 years, who are not currently included in Kerala’s universal immunization program. This can be achieved through collaboration with schools, healthcare providers, and community organizations to raise awareness and facilitate easy access to vaccinations.

    Mains PYQ: 

    Q What is the basic principle behind vaccine development? How do vaccines work? What approaches were adopted by the Indian vaccine manufacturers to produce COVID-19 vaccines? (UPSC IAS/2022)

  • Primary Amoebic Meningoencephalitis (PAM) Cases in Kerala

    Why in the News?

    There have been four cases, including three deaths, of the rare, but fatal brain-eating primary amoebic Meningoencephalitis (PAM) in Kerala in the last two months.

    What is Primary Amoebic Meningoencephalitis (PAM)?

    • PAM is a rare brain infection caused by Naegleria fowleri, a free-living amoeba found in warm freshwater and soil worldwide.
      • An amoeba is a type of cell or unicellular organism with the ability to alter its shape, primarily by extending and retracting pseudopods.
      • Higher temperatures of up to 115°F (46°C) are conducive to its growth and it can survive for short periods in warm environments.
    • The amoeba enters the body through the nose, typically during activities like swimming, and travels to the brain, causing severe damage.
    • PAM is also non-communicable.
    • Symptoms: Headache, fever, nausea, vomiting, stiff neck, confusion, seizures, hallucinations, and coma.
      • According to the US Centers for Disease Control and Prevention (CDC), most people with PAM die within 1 to 18 days after symptoms begin. It usually leads to coma and death after 5 days.

    Diagnosis and Treatment:

    • Currently, there are no established effective treatments for PAM.
    • Diagnosis involves PCR tests of cerebrospinal fluid, though detection can be challenging due to the rarity of PAM.
    • Treatment follows CDC guidelines, including miltefosine, Azithromycin, and Amphotericin B, with miltefosine recently procured by the State Health Department from Germany.
      • Medical interventions typically involve a combination of drugs, including amphotericin B, azithromycin, fluconazole, rifampin, miltefosine, and dexamethasone.

  • Four-year UG Program formally launched in Kerala

    Why in the News?

    Kerala CM Pinarayi Vijayan inaugurated the curriculum of Four-Year Undergraduate Programmes (FYUP) in the state, stressing that it is in line with changes in the Global Education System where the focus is equally on imparting knowledge as well as the transfer of skills and vocational training.

    About Four-Year Undergraduate Program (FYUP):

    Parameters Details
    Key features 
    • Students can choose their major and minor subjects freely, for example science students can pursue humanities courses.
    • Provision for students to complete the degree in 2.5 years if they secure the required credits.
    • Offers 16 FYUP honors programs with research across science, arts, commerce and business streams at the University of Kerala.
    FYUP curriculum
    • It is designed to provide students with knowledge, intellectual abilities, multidisciplinary perspectives, flexible skills, social commitment and research aptitude to make them responsible citizens and offer multiple opportunities in research and employment
    • Includes online courses, skill development, internships and research projects.
    Eligibility criteria
    • Students need a CGPA of 7.5 or above to advance to the 4th year and get an honors degree with research.
    •  Admission based on 12th marks for now, entrance exam planned from next year.

    Administrative and Technological Upgrades required:

    • Regulatory Revisions: Plans for a comprehensive revision of University Acts and Regulations to streamline academic processes and enhance efficiency.
    • K-REAP Initiative: Introduction of Kerala Resources for Education Administration and Planning (K-REAP), a governance software to centralize institutional activities.

    Issues with FYUP Program

    • Implementation Challenges: The introduction of the FYUP faced logistical and administrative hurdles, impacting its rollout across Kerala’s higher educational institutions.
    • Curriculum Adaptation: Critics argue that the FYUP’s curriculum overhaul lacks sufficient alignment with industry needs and fails to adequately prepare students for real-world challenges.
    • Student Adaptation: Some students and educators have expressed concerns about the abrupt shift in academic structure and its impact on learning outcomes and student performance.
    • Evaluation Methods: There is ongoing debate over the effectiveness of the FYUP’s assessment methods, with some stakeholders questioning its ability to accurately gauge student knowledge and skills.
    • Policy Revisions: Continuous revisions and adjustments to the FYUP’s policies and regulations are needed to address evolving educational needs and feedback from various stakeholders.

    New Education Policy (NEP), 2020:

    • The New Education Policy (NEP) 2020 introduced by the Government of India aims to transform the educational landscape of the country.
    • One of the key changes in the NEP is the restructuring of the duration and framework of undergraduate programs.
    • The NEP 2020 introduces a four-year undergraduate program as a standard duration for bachelor’s degrees, replacing the traditional three-year format.
    • Students can exit the program at different stages with a qualification. For example:
      • After 1 Year: Certificate
      • After 2 Years: Diploma
      • After 3 Years: Bachelor’s Degree
      • After 4 Years: Bachelor’s Degree with Research

     

    PYQ:

    [2015] The quality of higher education in India requires major improvement to make it internationally competitive. Do you think that the entry of foreign educational institutions would help improve the quality of technical and higher education in the country. Discuss.

  • What makes mosquitoes suck blood?

    Why in the News?

    A study published in the Proceedings of the National Academy of Sciences (PNAS) 1 has suggested that a pair of hormones work together to activate or suppress mosquitoes’ blood cravings.

    Mosquito Species and Behavior

    • There are around 3500 mosquito species globally, found on every continent except Antarctica.
    • Female mosquitoes consume blood to aid in egg development.
    • After feeding, female mosquitoes lose their appetite for blood until they lay their eggs.

    Research by Michael Strand and Team

    • Strand observed that levels of the mosquito gut hormone F (NPF) spiked when mosquitoes were seeking a host and dropped after feeding.
    • Their study analyzed mosquito enteroendocrine cells responsible for gut hormone production.
    • Hormonal Mechanisms:
      • NPF levels increased before blood meals and decreased six hours after feeding.
      • Another gut hormone, RYamide, was found to influence mosquitoes’ blood lust. As NPF levels decreased after a blood meal, RYamide levels increased, and vice versa.
      • The researchers concluded that NPF and RYamide work together to regulate mosquitoes’ attraction to humans and other hosts.

    Implications of the Study

    • Controlling the Deadliest Animal: Mosquitoes are the deadliest animal on the planet, acting as vectors for diseases such as malaria, dengue, West Nile virus, yellow fever, Zika, chikungunya, and lymphatic filariasis, which collectively kill more people than any other creature.
    • Pesticide Development: The discovery could lead to new pesticide targets for preventing mosquito reproduction and disease transmission.

    Note: Mosquitoes are responsible for over 1 million human deaths per year worldwide. They transmit deadly diseases like malaria, yellow fever, dengue, and Zika virus

    PYQ:

    [2023] ‘Wolbachia method’ is sometimes talked about with reference to which one of the following?

    (a) Controlling the viral diseases spread by mosquitoes
    (b) Converting crop residues into packing material
    (c) Producing biodegradable plastics
    (d) Producing biochar from thermo-chemical conversion of biomass

  • Universe had Spiral Galaxies 4 billion years sooner than expected: Study

    Why in the News?

    A new study has revealed more spiral galaxies in the universe’s youth than astronomers had previously expected.

    Universe’s Age and Galaxy Types

    • The universe is about 13.8 billion years old and hosts various kinds of galaxies, from spiral to elliptical.
    • Astronomers believed spiral galaxies formed about 6 billion years ago, but the new study calls this into question.
    • Younger galaxies tend to spiral, while older ones have a variety of shapes, making the study of older galaxies more challenging due to fainter light.

    Back2Basics: Spiral Galaxy

    • Spiral galaxies are a type of galaxy characterized by their spiral structure.
    • They are among the most common types of galaxies in the universe.
    • Our own Milky Way is a classic example of a spiral galaxy.

    Key Characteristics:

    • Central Bulge: A dense, spherical structure at the centre composed mainly of older stars.
    • Disk: Surrounding the bulge is a flat, rotating disk of stars, gas, and dust. The disk contains younger stars and spiral arms.
    • Spiral Arms: These are the defining features, winding outward from the central bulge. The arms are sites of active star formation and appear brighter due to the presence of young, hot stars.
    • Halo: A roughly spherical region surrounding the disk, containing old stars and globular clusters.

    Formation and Evolution:

    • Spiral galaxies are thought to form from the gravitational collapse of gas and dust in the early universe.
    • They maintain their structure through the rotation of the disk and the gravitational influence of the central bulge and halo.
    • Interactions and mergers with other galaxies can distort or destroy their spiral structure, potentially transforming them into elliptical galaxies.

    Formation of Galaxies

    • As the universe cooled from a dense plasma state, hot gas formed clumps that became galaxies.
    • These early galaxies had irregular shapes and lacked disks.
    • Spiral Formation Theory:
      • The traditional theory suggested that it took billions of years for hot, thick disks to become thinner and form spiral arms.
      • The new study suggests that cooling and spiral formation occur around the same cosmic time.

    How is this verified?

    • Astronomers observe star formation in real time but study galaxy evolution through “astronomical archaeology.”
      • Understanding the fraction of spiral galaxies helps astronomers trace the biography of galaxies.
      • Infrared and optical wavelengths are used to detect early galaxies, requiring powerful telescopes due to the faint light of older galaxies.
    • Study Methodology:
      • The University of Missouri team used the JWST to study 873 galaxies and identified at least 216 spiral galaxies, some dating to 1.5 billion years after the universe’s birth.
      • Each of the six authors classified the images as spiral or non-spiral, ensuring the result is free of human bias.

    Findings and Implications

    • The fraction of spiral galaxies increased from about 8% to 48% between 3 billion and 7 billion years after the Big Bang, higher than previously observed.
    • The study challenges existing models and suggests that galaxy formation theories need to be more complex.

    PYQ:

    [2022] Launched on 25th December, 2021, James Webb Space Telescope has been much in the news since then. What are its unique features which make it superior to its predecessor Space Telescopes? What are the key goals of this mission? What potential benefits does it hold for the human race?

  • Digital jurisprudence in India, in an AI era  

    Why in the news?

    Generative AI’s transformative potential challenges existing legal frameworks and judicial precedents, which are inadequate for effectively governing this rapidly-evolving technology designed for a pre-AI world.

    What is Generative AI?

    • Generative AI refers to artificial intelligence models that can generate original content like text, images, videos, and audio in response to prompts or requests.
    • These models learn patterns from large datasets and use that knowledge to create new content that resembles the training data.

    Persistent and Contentious Issues in Internet Governance

    Safe Harbour and Liability Fixation:

    • The Shreya Singhal judgment upholds Section 79 of the IT Act, granting intermediaries ‘safe harbour’ protection against liability for hosted content, contingent upon meeting due diligence requirements.
    • Challenges arise in applying these provisions to GAI tools, with debates on whether they should be classified as intermediaries, conduits, or active creators.
    • The Delhi High Court’s ruling in the Christian Louboutin Sas vs Nakul Bajaj and Ors (2018) case limited safe harbour protection to “passive” intermediaries.
    • The classification of GAI tools complicates the assignment of liability, especially in cases of user reposts.

    Generative AI and Legal Conflicts:

    • GAI outputs have led to legal conflicts, such as a lawsuit in the U.S. against OpenAI for defamation by ChatGPT.
    • Ambiguities in classifying GAI tools complicate legal decisions regarding liability.

    What Does the Indian Copyright Act 1957 Say?

    • Section 16 specifies that copyright protection is granted only under the provisions of the Act, with reluctance globally to extend protection to AI-generated works.
    • Critical questions include whether existing copyright laws should be revised for AI, the need for co-authorship with humans, and the responsibility for copyright infringement by AI tools.
    • The 161st Parliamentary Standing Committee Report highlights the inadequacy of the Copyright Act to facilitate AI authorship and ownership.
    • Current Indian law allows copyright owners to take legal action against infringement, but liability for AI-generated content remains unclear.

    Steps to Pursue (Way forward)

    • Learning by Doing: Implement a sandbox approach, granting temporary immunity from liability to GAI platforms for responsible development and data gathering to inform future regulations.
    • Data Rights and Responsibilities: Overhaul the data acquisition process for GAI training, ensuring legal compliance, proper licensing, and compensation for intellectual property used in training models. Potential solutions include revenue-sharing or licensing agreements with data owners.
    • Simplify the Licensing: Licensing data for GAI is complex due to the lack of a centralized licensing body for web data. The creation of centralized platforms, similar to stock photo websites, can simplify licensing, streamline access to data, and ensure data integrity against bias and discrimination.
    • Government and Judicial Approach to maximize the benefits of GAI: A comprehensive re-evaluation of existing digital jurisprudence is needed, requiring a holistic, government-wide approach and judicious interpretations by constitutional courts. The aim is to maximize the benefits of GAI while safeguarding individual rights and protecting against unwelcome harm.

    Mains PYQ:

    Q The emergence of the Fourth Industrial Revolution (Digital Revolution) hasinitiated e-Governance as an integral part of government”. Discuss. (UPSC IAS/2020)

  • On Improving Rural Mobile Connectivity 

    Why in the news? 

    On June 6, IEEE endorsed a wireless network structure aimed at providing economical broadband access in rural areas, formulated at IIT Bombay.

    About the latest Telecom Subscription Data        

    • Urban Tele-density: Urban tele-density in India is 127%, indicating that on average, each urban user has more than one mobile connection.
    • Rural Tele-density: Rural tele-density is significantly lower at 58%, meaning only about one in two rural residents has a mobile connection.
    • Urban-Rural Digital Divide: The data highlights a stark contrast between urban and rural areas, with urban areas having much higher mobile connectivity compared to rural regions, reflecting a significant digital divide.

    What are access and core networks?

    • Access Network (AN): The AN consists of base stations that provide wireless connectivity to mobile devices within a limited geographical area. It interfaces directly with mobile devices, facilitating communication and data transfer between devices and the wider network.
    • Core Network (CN): The CN comprises centralized network equipment that manages and directs data traffic between the access network, other networks (like the Internet), and service providers. It handles tasks such as routing, switching, and managing connectivity across the broader network infrastructure.

    What impedes rural connectivity?

    • Affordability: Lower income levels in rural areas make mobile services relatively expensive, limiting access for many rural residents.
    • Cost of Infrastructure: Installing and maintaining network infrastructure like fibre optics in remote rural areas is costly and may not be economically viable for service providers.
    • Low Population Density: Rural areas often have sparse populations spread over large geographic areas, making it less profitable for network operators to invest in infrastructure deployment.
    • Geographical Barriers: Difficult terrains and remote locations further complicate the installation of base stations and backhaul infrastructure necessary for robust network coverage.
    • Urban Bias in Technology: Most advancements in cellular networks, such as 5G, prioritize high data rates and low latency suitable for urban environments, neglecting the unique challenges of rural areas.
    • Limited Research: There has been insufficient research focused on developing cost-effective solutions that can efficiently cover large rural areas with adequate connectivity.

    What is the IEEE 2061-2024 standard? (Its working and architecture)   

    • IEEE 2061-2024 aims to establish a standardized wireless network architecture for affordable broadband access in rural areas.
    • It defines a heterogeneous Access Network (AN) comprising macro base stations (Macro-BS) and Wi-Fi base stations, integrated with a flexible Core Network (CN) bypass capability.

    Architecture:

    • Heterogeneous AN: Includes Macro-BS covering large areas with potentially lower data rates, complemented by Wi-Fi base stations deployed within villages for high-speed connectivity.
    • CN Bypass: Allows direct Internet access from the AN, bypassing the centralized Core Network for certain communications. This enhances efficiency and reduces latency, catering to stationary users common in rural settings.
    • Middle-Mile Connectivity: Utilizes multi-hop wireless networks (e.g., satellites, long-range Wi-Fi) to extend connectivity over long distances where optical fibre deployment is impractical or costly.

    What is a middle-mile network?

    • A middle-mile network refers to the infrastructure that connects core network hubs to local access points, spanning intermediate distances. It uses technologies like fibre optics, microwave links, or satellites to transport data between central and regional locations, facilitating efficient connectivity over longer distances without the need for direct local access networks.

    Conclude: To bridge the urban-rural digital divide in telecom, measures should focus on affordability through subsidized services, incentivizing infrastructure investment in rural areas, promoting research on rural-specific technologies, and ensuring equitable access to advanced wireless standards like IEEE 2061-2024.

    Mains PYQ: 

    Q Has digital illiteracy, particularly in rural areas, coupled with a lack of Information and Communication Technology (ICT) accessibility hindered socio-economic development? Examine with justification. (UPSC IAS/2021)

  • India lacks diagnostic tests for emerging infectious diseases

    Why in the news?

    The detection of a Zika virus infection in Pune has once again raised concerns regarding India’s readiness to diagnose emerging infectious diseases.

    Recent Outbreaks in Various Regions of India

    • Zika Virus: Recent cases of Zika virus in Pune and previous outbreaks in Kerala and Uttar Pradesh highlight sporadic but concerning outbreaks across India.
    • Avian Influenza: Ongoing outbreaks affecting poultry, with occasional human cases reported, indicating challenges in surveillance and testing.
    • Nipah Virus: Multiple outbreaks in Kerala and sporadic cases in West Bengal underscore the recurrent nature of Nipah virus outbreaks in India.

    India’s Lack of Significant Zika Surveillance and Other Diseases

    • Limited Diagnostic Capabilities: India faces challenges with the absence of approved diagnostic tests for the Zika virus, relying on clinical symptoms and selective testing, which may lead to underreporting.
    • Surveillance Gaps: There is a notable gap in systematic surveillance systems specifically tailored for Zika and other emerging infectious diseases, hampering early detection and containment efforts.
    • Infrastructure Deficiencies: The country’s diagnostic infrastructure outside major institutes is inadequate, affecting the timely identification and response to outbreaks of diseases like Zika, Nipah, and avian influenza.
    • Dependency on Apex Institutes: Diagnostic facilities are largely concentrated in apex national institutes, limiting accessibility and delaying the implementation of crucial public health measures during outbreaks.

    Impacts of Unavailability of Infrastructure

    • Delayed Response: Lack of accessible diagnostics delays the identification and isolation of cases, contact tracing, and implementation of containment measures during outbreaks.
    • Loss of Time: Delays in releasing genomic sequences and validating diagnostic tests impede the rapid development and deployment of effective diagnostics.

    Way Forward (Role of ICMR)

    • Enhanced Surveillance: ICMR (Indian Council of Medical Research) should lead efforts to decentralize testing facilities, ensuring availability at district and sub-district levels.
    • Capacity Building: Develop accessible and affordable diagnostic tests for Zika, Nipah, and avian influenza, leveraging lessons from COVID-19 testing infrastructure expansion.
    • Genomic Surveillance: Establish a system for the rapid release of whole genome sequences into public repositories like GISAID to enhance understanding and response capabilities.
    • Collaboration: Foster collaboration with industry and research institutions to streamline diagnostic test approvals and improve preparedness for future outbreaks.

    Mains PYQ: 

    Q COVID-19 pandemic has caused unprecedented devastation worldwide. However, technological advancements are being availed readily to win over the crisis. Give an account of how technology was sought to aid the management of the pandemic. (UPSC IAS/2020)

  • What was the tussle over Covaxin IPR?

    Why in the News?

    • Bharat Biotech International Limited (BBIL), maker of the indigenous coronavirus vaccine Covaxin, admitted to an “inadvertent error” in patent filings. The error involved failing to include scientists from the Indian Council of Medical Research (ICMR) as co-inventors in the patent filings.

    COVAXIN Story

    • BBIL patented the process of making a batch of vaccines from virus strains provided by ICMR-NIV (National Institute of Virology).
    • ICMR-NIV’s role involved extracting viruses, identifying characteristics, conducting tests, and qualifying strains for vaccine development.
      • ICMR funded these clinical trials with ₹35 crore and incurred costs in developing Covaxin.
      • In return, ICMR was to receive 5% of the royalties BBIL earned from the sale of Covaxin.

    Vaccine Patents in India 

    • In India, patents, including those for vaccines, are governed by the Patents Act, 1970, and its subsequent amendments.
    • This act aligns with the TRIPS Agreement (Trade-Related Aspects of Intellectual Property Rights) under the World Trade Organization (WTO).

    Key Provisions of the Patents Act, 1970:

    • Patentable Inventions:
        • An invention must be novel, involve an inventive step, and be capable of industrial application.
        • Section 3 of the Patents Act outlines what are not considered inventions, which includes methods of treatment, and processes for medicinal, surgical, curative, prophylactic, diagnostic, therapeutic, or other treatments of human beings.
    • India grants both process and product patents:
      • Product Patents: Grant a monopoly over a specific drug.
      • Process Patents: Prevent competitors from using the same sequence of steps to create a similar product.
    • Compulsory Licensing:
      • Under Section 84, compulsory licenses can be issued if the patented invention is not available to the public at a reasonably affordable price, or if the reasonable requirements of the public are not being met.
    • Bolar Provision:
      • Section 107A allows the use of patented inventions, including vaccines, for the purpose of research and development to obtain regulatory approval before the patent expires.

    Why was the ICMR not included?

    • Bharat Biotech initially excluded ICMR from patent applications because they viewed the ICMR’s role primarily as providing virus strains and conducting clinical trials, rather than being directly involved in the technical processes of vaccine development.
    • There might have been a miscommunication or oversight regarding the understanding of intellectual property rights and inventorship between BBIL and ICMR initially.

     

    PYQ:

    [2013] Bringing out the circumstances in 2005 which forced amendment to the section 3(d) in Indian Patent Law, 1970, discuss how it has been utilized by the Supreme Court in its judgement in rejecting Novartis’ patent application for ‘Glivec’. Discuss briefly the pros and cons of the decision. (200 words)

    [2014] In a globalized world, Intellectual Property Rights assume significance and are a source of litigation. Broadly distinguish between the terms—Copyrights, Patents and Trade Secrets.

  • Activated Carbon Production from Coconut Husks for Supercapacitors

    Why in the News?

    Researchers at Government College for Women, Thiruvananthapuram, have developed a way to make activated carbon from coconut husks, which are a common leftover from farming in Kerala. This activated carbon is well-suited for making supercapacitors.

    Back2Basics: Supercapacitors

    • Supercapacitors, also known as ultra-capacitors or electrochemical capacitors, are energy storage devices that bridge the gap between conventional capacitors and batteries.
    • They store energy through the electrostatic separation of charges rather than through chemical reactions as in batteries.
    • This allows supercapacitors to charge and discharge much faster than batteries.

    Key Characteristics:

    • High Power Density: Supercapacitors can deliver and accept charge much more rapidly than batteries.
    • Long Cycle Life: They can endure millions of charge-discharge cycles without significant degradation.
    • Wide Operating Temperature Range: Supercapacitors perform well in a broad range of temperatures, making them suitable for various applications.

    Structure and Components:

    • Electrodes: Made of materials like activated carbon, carbon aerogels, or graphene, which have high surface areas.
    • Electrolyte: The medium that allows ionic conductivity between the electrodes, typically a liquid or gel.
    • Separator: A porous membrane that prevents electrical contact between the electrodes but allows ionic movement.

    What is Activated Carbon?

    • Activated Carbon, also known as activated charcoal, is a highly porous form of carbon.
    • It is processed to have small, low-volume pores with increased surface area available for adsorption or chemical reactions.
    • It is widely used for purification, decontamination, and as a filtration medium.
    • Key Characteristics:
      • High Surface Area: Due to its extensive network of pores, activated carbon has a very high surface area, typically ranging from 500 to 1500 m²/g.
      • Porosity: The structure includes micropores, mesopores, and macropores, allowing it to adsorb a variety of molecules.

    How is it produced?

    • Activated carbon is produced from carbonaceous source materials such as coconut shells, peat, wood, coir, lignite, coal, and petroleum pitch.
    • The production involves two main steps:
    1. Carbonization: The raw material is subjected to high temperatures (600-900°C) in an inert atmosphere (usually nitrogen or argon) to remove volatile components.
    2. Activation/Oxidation: The carbonized material is treated with oxidizing agents (such as steam or carbon dioxide) at high temperatures (800-1000°C) to develop a porous structure.

    Types:

    • Powdered Activated Carbon (PAC): Finely ground carbon particles primarily used in liquid phase applications.
    • Granular Activated Carbon (GAC): Larger particles used in both liquid and gas phase applications, such as water and air filtration.
    • Extruded Activated Carbon (EAC): Cylindrical pellets used mainly for gas phase applications due to their low pressure drop and high mechanical strength.
    • Impregnated Activated Carbon: Activated carbon treated with chemicals to enhance its adsorption capacity for specific contaminants.

    Applications:

    • Water Treatment: Removes contaminants like chlorine, odors, and organic compounds from drinking water.
    • Air Purification: Adsorbs volatile organic compounds (VOCs), odors, and airborne pollutants.
    • Medical Uses: Used in poisoning cases to absorb toxins in the gastrointestinal tract.
    • Industrial Processes: Utilized in the recovery of solvents, purification of gases, and in gold purification.
    • Food and Beverage: Helps in decolorization and purification processes in sugar, wine, and juice production.

    About Coconut Husk-Derived Activated Carbon

    • Coconut husk-derived activated carbon is a sustainable and efficient green solution for high-performance supercapacitors.
    • This material is readily available, low-cost, and eco-friendly.
    • It was produced by Microwave-Assisted Method designed at the Centralised Common Instrumentation Facility (CCIF) at the college.

    Importance of Supercapacitors

    • Energy Storage: Supercapacitors have significantly higher capacitance and energy storage capacity compared to conventional capacitors.
    • Search for Ideal Material: Finding the ideal supercapacitor electrode material has been a significant challenge in sustainable energy storage solutions.

    Research Findings:

    • Efficiency: Prototype supercapacitors made from coconut husk-derived activated carbon are four times more efficient than existing supercapacitors.
    • Cost-Effective and Efficient: Activated carbon produced using this technology is inexpensive and exhibits exceptional supercapacitor capability.