💥Join UPSC 2027,2028 Mentorship (July Batch) + XFactor Notes & Microthemes PDF

Subject: Science and Technology

  • Spirulina Groundnut Chikki to boost immunity

    The Mysuru-based Central Food Technological Research Institute, CFTRI has developed Spirulina groundnut Chikki that can provide micro-nutrients and boost the immunity of people during this time of the pandemic.

    Beware, the Chikki so mentioned has no GI tag. What makes it significant is the Spirulina, a photosynthetic bacteria, which is suitable for human consumption.

    Spirulina Groundnut Chikki

    • It is a snack that provides good micro-nutrients.
    • It has used Spirulina as well as the tasty, nourishing groundnuts to prepare Chikki that is rich in micro-nutrients such as Vitamin A, Beta Carotene and easily digestible algal proteins.
    • Other nutritious snacks of CFTRI such as Nutri mango fruit bar and cardamom flavoured water is also part of the food items supplied to the migrant labourers.
    • The mango bar is rich with carbohydrates, carotene, Vitamin C and Zinc to improve the immunity.
    • Cardamom flavoured water with traditional herbs to have immune booster qualities.

    What is Spirulina?

    • Spirulina is an organism that grows in both fresh and saltwater.
    • It is a type of cyanobacteria, which is a family of single-celled microbes that are often referred to as blue-green algae.
    • It is used as a dietary supplement or whole food. It is also used as a feed supplement in the aquaculture, aquarium, and poultry industries.
    • Just like plants, cyanobacteria can produce energy from sunlight via a process called photosynthesis.
  • Toda Embroidery of the Nilgiris

    Many women and indigenous Toda artisans from the Nilgiris are producing thousands of stylish, embroidered masks for local residents, police, and sanitary workers.

    Recently, the Assamese Gamosa was in new. Now the Pukhoor Embroidery has made it into the list. Keep a note of all such handicrafts. We can expect a match the pair based prelim question.

    Toda Embroidery

    • The Toda Embroidery, also locally known as “pukhoor” is an artwork among the Toda pastoral people of Nilgiris, in Tamil Nadu, made exclusively by their women.
    • The embroidery, which has a fine finish, appears like a woven cloth but is made with the use of red and black threads with a white cotton cloth background.
    • Both sides of the embroidered fabric are usable and the Toda people are proud of this heritage.
    • This handicraft product is listed as a geographically tagged product and is protected under the Geographical Indications of Goods (Registration & Protection) Act (GI Act) 1999.

    Related facts

    • The local terms used to describe the embroidery work are ‘kuty’ or ‘awtty’ meaning “stitching” and ‘kutyvoy’ meaning the embroidered piece.
    • The materials used in this work are roughly woven white cloth, woollen black and red threads with use occasionally of blue threads and manufactured needles.
    • The designs developed relate to nature and the daily cycle of life.
    • The patterns used in Toda embroidery do not cover many floral motifs but generally cover celestial bodies (like Sun and Moon), reptiles, animals, and horns of buffaloes, made in crimson and black colours.
    • Rabbit ears are a constant depiction on the boundary of the embroidered cloth. Another common design in the form of black triangles in a box design is done in honour of their first priest.
    • Women who do embroidery consider their work as a “tribute to Nature”.
    • As a traditional garment, it is worn by both men and women at all ceremonial occasions and also at funerals. Elderly people of the community wear this cloth daily.
  • [pib] BiPAP Non-Invasive Ventilator “SwasthVayu”

    National Aerospace Laboratories (NAL) Bangalore, a constituent of the lab of CSIR has developed a Non-Invasive BiPAP Ventilator ‘SwasthVayu ’in a record time of 36 days to treat COVID-19 patients.

    The name ‘SwasthVayu’ can be tricky to guess, specially after some days. In prelims, UPSC may throw some options related to air pollution.

    SwasthVayu

    • A ventilator is a machine that provides mechanical ventilation by moving breathable air into and out of the lungs, to deliver breaths to a patient who is physically unable to breathe, or breathing insufficiently.
    • BiPAP (Bilevel Positive Airway Pressure) Non-Invasive ventilator is a microcontroller-based precise closed-loop adaptive control system.
    • It is a built-in biocompatible “3D printed manifold & coupler” with HEPA filter (Highly Efficient Particulate Air Filter).

    Benefits of SwasthVayu

    • The major advantage of this machine is that it is simple to use without any specialized nursing, cost-effective, compact and configured with the majority of indigenous components.
    • This is ideal for treating COVID -19 patients in Wards, Makeshift Hospitals, dispensaries and home in current Indian COVID 19 scenario.
  • Indigenous antibody test: COVID Kavach ELISA

    Indian Council of Medical Research (ICMR)-National Institute of Virology (NIV) at Pune has developed and validated the indigenous IgG ELISA test “COVID KAVACH ELISA” for antibody detection for COVID-19.

    Our thumb rule suggests that the ELISA test is being used only for the diagnosis of HIV infection. Right?

    But the ELISA test is a broader term to diagnose antibody-antigen interaction after certain virus infection to a person.  UPSC can test your basic knowledge of core biology with a question based on this concept.

    What is ELISA test?

    • ELISA (enzyme-linked immunosorbent assay) is a plate-based assay technique designed for detecting and quantifying substances such as peptides, proteins, antibodies and hormones.
    • Other names, such as enzyme immunoassay (EIA), are also used to describe the same technology.
    • In an ELISA, an antigen must be immobilized on a solid surface and then complexed with an antibody that is linked to an enzyme.
    • Detection is accomplished by assessing the conjugated enzyme activity via incubation with a substrate to produce a measurable product.
    • The most crucial element of the detection strategy is a highly specific antibody-antigen interaction.

    What are antibodies?

    • An antibody is a large, Y-shaped protein produced mainly by plasma cells that are used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.
    • There are five immunoglobulin classes (isotypes) of antibody molecules found in serum: IgG, IgM, IgA, IgE and IgD.
    • They are distinguished by the type of heavy chain they contain.

    Application of ELISA

    • Presence of antigen or the presence of antibody in a sample can be evaluated
    • Determination of serum antibody concentrations in a virus test
    • Used in the food industry when detecting potential food allergens
    • Applied in disease outbreaks- tracking the spread of disease e.g. HIV, bird flu, common, colds, cholera, STD etc

    Significance

    • Robust antibody tests are critical for surveillance to understand the proportion of the population exposed to infection.
    • The test will have the advantage of testing 90 samples together in a single run of 2.5 hours.
    • Moreover, ELISA based testing is easily possible even at the district level as the ELISA kit has an inactivated virus.
    • There are also minimal bio-safety and bio-security requirements as compared to the real-time RT-PCR test.
    • The test has the advantage of having much higher sensitivity and specificity as compared to the several rapid test kits which have recently flooded the Indian market.

    Limitations

    • Since the ELISA test is based on the detection of antibodies, it can only help in knowing if the person has been previously infected by a coronavirus.
    • It takes one-three weeks for the antibodies to develop in response to infection.
    • So, if a person who has been recently infected by the virus is tested during the window period (the time taken to develop antibodies) the result will turn out to be negative.
    • But a repeat test after a couple of weeks will indicate the true infection status.

    How it is different from the PCR test?

    • While the RT-PCR, which detects the RNA of the coronavirus, enables detection of current infection, it will not be useful if the testing is carried out days after the infection clears as the virus will no longer be present.
    • However, antibodies developed in response to the coronavirus infection will be present in the blood for a longer duration and hence the ELISA test can help detect past infection.
    • The maximum time the antibodies will be present in the body is not known for coronavirus.

    Back2Basics: Reverse Transcriptase – Polymerase Chain Reaction (PCR) Test

    • It uses a technique that creates copies of a segment of DNA. ‘Polymerase’ refers to the enzymes that make the copies of DNA.
    • Kary Mullis, the American biochemist who invented the PCR technique, was awarded the Nobel Prize for Chemistry in 1993.
    • The ‘chain reaction’ is how the DNA fragments are copied, exponentially — one is copied into two, the two are copied into four, and so on.
    • However, SARS-COV-2 is a virus made of RNA, which needs to be converted into DNA. For this, the technique includes a process called reverse transcription.
    • A ‘reverse transcriptase’ enzyme converts the RNA into DNA. Copies of the DNA are then made and amplified.
    • A fluorescent DNA binding dye called the “probe” shows the presence of the virus. The test also distinguishes SARS-COV-2 from other viruses.
  • What is African Swine Fever (ASF)?

    • Amid the coronavirus pandemic, another disease outbreak is affecting thousands of animals in Assam.
    • Since February, over 2,900 pigs have died in the state due to African Swine Fever (ASF), which does not affect humans but can be catastrophic for pigs.
    • This is the first time that an ASF outbreak has been reported in India.

    As Flu is nowadays a lot in news, keep a tab on them for prelims. Be it the Swine Flue, African Swine Fever or even H5N1.

    African Swine Fever (ASF)

    • ASF is a severe viral disease that affects wild and domestic pigs typically resulting in an acute hemorrhagic fever.
    • The disease has a case fatality rate (CFR) of about 100 per cent.
    • Its routes of transmission include direct contact with an infected or wild pig (alive or dead), indirect contact through ingestion of contaminated material such as food waste, feed or garbage or through biological vectors such as ticks.
    • The disease is characterized by the sudden deaths of pigs.
    • Other manifestations of the disease include high fever, depression, anorexia, loss of appetite, hemorrhages in the skin, vomiting and diarrhoea among others.

    How did the current outbreak start?

    • As per the latest update issued by FAO, the current outbreak of ASF has affected China, Mongolia, Vietnam, Cambodia, Myanmar, the Philippines, Republic of Korea and Indonesia among others.
    • In China, the first ASF outbreak was confirmed in August 2018 and since then more than 1 million pigs have been culled in the country.
    • ASF came into India through Tibet into Arunachal Pradesh and then into Assam, the state with the highest population of pigs in the country.

    How is ASF different from swine flu?

    • Swine influenza or swine flu is a respiratory disease of pigs, which is caused by type A influenza virus that regularly causes outbreaks of influenza in pig populations.
    • While the swine flu causing virus leads to a high number of infections in pig herds, the disease is not as fatal and causes few deaths. Specific swine influenza vaccines are available for pigs.
    • The swine flu viruses are spread among pigs through close contact and through contaminated objects moving between infected and uninfected pigs.
    • Symptoms include fever, depression, coughing, discharge from the nose and eyes, eye redness or inflammation.

    Vaccines availability

    • As of now, there is no approved vaccine, which is also a reason why animals are culled to prevent the spread of infection.
    • It is important that determination of ASF is made through laboratory testing and it is differentiated from Classical Swine Fever (CSF), whose signs may be similar to ASF, but is caused by a different virus for which a vaccine exists.
    • Even so, while ASF is lethal, it is less infectious than other animal diseases such as foot-and-mouth disease.

    What is the impact ASF will have on pig farmers?

    • Pig farmers in Assam describe the outbreak as a “double whammy” since the COVID-19 lockdown was already impacting sales negatively.
    • The outbreak has ruined the prospect of the Northeastern states as a hub for the export of pork products.
  • Luhman 16A: A binary brown-dwarf system

    A group of international astrophysicists have identified cloud bands on the surface of Luhman 16A, one of a pair of binary brown dwarfs in the Vela constellation.

    Space terminology has gained importance in prelims. The Luhman 16A coupled with few more examples of space concepts like binary star and dwarf star are discussed in this newscard.

    Luhman 16A

    • Luhman 16 is a binary star system, the third closest system to the Sun after Alpha Centauri and Barnard’s star.
    • At a distance of about 6.5 light-years from the Sun, this pair of brown dwarfs referred to as Luhman 16A and Luhman 16B orbit each other, casting a dim light.
    • Brown dwarfs are also called failed stars because their masses are intermediate to the largest planets and the smallest main sequence stars.
    • Their masses being too small, they are unable to sustain fusion of their hydrogen to produce energy.
    • It is believed that some of the more massive brown dwarfs fuse deuterium or lithium and glow faintly.

    The cloud band over Luhman

    • The group, by using the Very Large Telescope at European Southern Observatory, Chile, found that Luhman 16A had band-like clouds in its atmosphere, whereas the same was not true of Luhman 16B.
    • Many astronomers detected polarization of brown dwarfs.
    • But what is special in the newest study of Luhman 16 is that the researchers have found the actual structure of the clouds — that they form bands over one of the pair.
    • Understanding the cloud system over a brown dwarf can shed light on the pressure, temperature and climate on the surface of the celestial body.

    Why it has made into a headline?

    • The researchers have used an idea put forth nearly two decades ago by Indian astrophysicist Sujan Sengupta, who works at the Indian Institute of Astrophysics, Bengaluru.
    • Sengupta had propounded the light emitted by a cloudy brown dwarf, or reflected off an extrasolar planet, will be polarized.
    • He then suggested that a polarimetric technique could serve as a potential tool to probe the environment of these objects.

    Back2Basics: Binary Star System

    • A binary star is a star system consisting of two stars orbiting around their common barycenter.
    • Systems of two or more stars are called multiple star systems.
    • These systems, especially when more distant, often appear to the unaided eye as a single point of light, and are then revealed as multiple by other means.
    • Binary star systems are very important in astrophysics because calculations of their orbits allow the masses of their component stars to be directly determined.
  • [pib] Energy-efficient Photodetector for Security Application

    Indian scientists have fabricated an economical and energy-efficient wafer-scale photodetector using gold – silicon interface, for security applications.

    A basic question on the working principle of Photodetectors can be asked in the Prelims.

    What are Photodetectors?

    • Photodetectors, also called photosensors, are sensors of light or other electromagnetic radiation.
    • A photodetector has a p–n (positive-negative) junction that converts light photons into the current.
    • The absorbed photons make electron-hole pairs in the depletion region.
    • Photodiodes and phototransistors are a few examples of photodetectors. Solar cells convert some of the light energy absorbed into electrical energy.
    • The material cost and the intricate fabrication processes involved in realizing high-performance detectors make them unaffordable for day to day applications.

    Applications

    • Photodetectors are the heart of any optoelectronic circuit that can detect light.
    • They are employed for a wide variety of applications ranging from controlling automatic lighting in supermarkets to detecting radiation from the outer galaxy as well as security-related applications.
    • They range from simple devices that automatically open supermarket doors, to receivers on the TV remote controls.

    What did Indian researchers achieve?

    • The scientists have fabricated gold (Au) – silicon (Si) interface, which showed high sensitivity towards light demonstrating the photodetection action.
    • The Au–Si interface was brought about by galvanic deposition, a technique for electroplating of metals, wherein water-based solutions (electrolytes) are used, which contain the metals to be deposited as ions.
    • In addition, a nanostructured Au film also was deposited on top of p-type silicide (having an excess of positive charges), which acts as a charge collector.

    Benefits

    • Being a solution-based technique, the method is highly economical and enabled large-area fabrication without compromising the detector response.
    • The process is quick, taking only minutes to fabricate a detector of any arbitrary area and exhibited a rapid response of 40 microseconds.
    • This photodetector displayed long-term environmental stability.
    • The Indian invention provides a simple and cost-effective solution-based fabrication method for high-performance photodetector.
    • It could help detect weak scattered light as an indication of unwanted activity.
  • ‘The Long March 5B’ rocket

    China has successfully launched a new rocket and prototype spacecraft in a major test of the country’s ambitions to operate a permanent space station and send astronauts to the Moon.

    Can you recall the historical link between the name “The Long March” and China’s History.

    The Long March 5B

    • Long March 5 or Chang Zheng 5 is a Chinese heavy-lift launch system developed by the China Academy of Launch Vehicle Technology (CALT).
    • It is the first Chinese launch vehicle designed from the ground up to focus on non-hypergolic liquid rocket propellants.
    • The maximum payload capacities of the base variant are ~25,000 kilograms to Low Earth Orbit and ~14,000 kilograms to Geosynchronous Transfer Orbit.
    • The spaceship is expected to transport astronauts to a space station that China plans to complete by 2022 — and eventually to the Moon. It will have a capacity for a crew of six.

    Back2Basics: Geosynchronous Transfer Orbit

     

    • About 35,786 kilometers above the Earth’s surface, satellites are in geostationary orbit. From the center of the Earth, this is approximately 42,164 kilometers. This distance puts it in the high Earth orbit category.
    • At any inclination, a geosynchronous orbit synchronizes with the rotation of the Earth.
    • While geosynchronous satellites can have any inclination, the key difference to geostationary orbit is the fact that they lie on the same plane as the equator.
    • GTO is a an elliptical orbit used to transfer between two circular orbits of different radiuses in the same plane—used to reach geosynchronous or  geostationary orbit using high-thrust chemical engines.
  • How Remdesivir tricks coronavirus?

    A new research has found how Remdesivir treats coronavirus and described the exact mechanism of interaction between the virus and the drug.   Remdesivir is an experimental antiviral made by American pharmaceutical firm Gilead Sciences that was first developed to treat Ebola.

    DNA/RNA related terminologies, Genes and Genomes, etc. always find their way in UPSC Prelims.  Most recent one was-

    With reference to the recent developments in science, which one of the following statements is not correct? (CSP 2019)

    (a) Functional chromosomes can be created by joining segments of DNA taken from cells of different species.

    (b) Pieces of artificial functional DNA can be created in Iaboratories.

    (c) A piece of DNA taken out from an animal cell can be made to replicate outside a living cell in a laboratory.

    (d) Cells taken out from plants and animals can be made to undergo cell division in laboratory petri dishes.

    How Remdesivir kills coronavirus?

    • Remdesivir is designed to obstruct the stage of replication, when the virus creates copies of itself, followed endlessly by the copies creating copies of themselves.

    How does replication take place?

    • Once the virus enters the human cell, it releases its genetic material, which is then copied using the body’s existing mechanism.
    • At every stage of infection, various human proteins, virus proteins, and their interactions come into play.
    • At the replication stage, the key viral protein at play is an enzyme called RdRp (an enzyme is a kind of protein that speeds up chemical reactions within a cell).
    • It is RdRp that makes the copies, by processing components of the RNA of the virus.
    • University of Alberta researchers called it the “engine” of the virus in a paper last week, in which they described the action of Remdesivir against this “engine”.
    • In scientific literature, such an enzyme is called a polymerase (the p is RdRp stands for polymerase) or a replica.
    • In any case, this is the enzyme that is targeted by Remdesivir.

    And how exactly does Remdesivir target this enzyme?

    • In order to replicate, the virus processes raw material from the virus RNA, broken down by another enzyme with that specific function.
    • When a patient is given Remdesivir — the inhibitor — it mimics some of this material and gets incorporated in the replication site.
    • With Remdesivir replacing the material it needs, the virus fails to replicate further.
    • These coronavirus polymerases are sloppy and they get fooled, so the inhibitor gets incorporated many times and the virus can no longer replicate.
  • Bay of Bengal Boundary Layer Experiment (BoBBLE)

    A team from IISc Bengaluru and UK based researchers has created a blueprint for accurate prediction of monsoon, tropical cyclones and another weather-related forecast under the BoBBLE Experiment.

    Aspirants must note:

    1) BoBBLE is headed by which organizations?

    2) Its purpose and application

    What is BoBBLE?

    • The Bay of Bengal Boundary Layer Experiment or BoBBLE in short is a project funded by Union Ministry of Earth Sciences and the Natural Environment Research Council of UK.
    • BoBBLE tries to determine, quantify and model ocean-atmosphere interactions that drive variability in the South Asian monsoon.
    • The experiment created a blueprint for future weather system observational experiments for accurately forecasting monsoon rainfall.

    Why need BoBBLE?

    • The Bay of Bengal (BoB) plays a fundamental role in controlling the weather systems that make up the South Asian summer monsoon system.
    • In particular, the southern BoB has cooler sea surface temperatures (SST) that influence ocean-atmosphere interaction and impact the monsoon.
    • Compared to the southeastern BoB, the southwestern BoB is cooler, more saline receives much less rain, and is influenced by the summer monsoon current (SMC).
    • To examine the impact of these features on the monsoon, the BoB Boundary Layer Experiment (BoBBLE) was undertaken.

    BONUS:

    1) How technology development in monsoon forecasting can benefit realizing the dream of doubling farmers income by 2022?

    2) Discuss the role of Bay of Bengal in monsoon dynamics. (Hint: the link between the two lies in Indian Ocean Dipole (IOD))

    How is the experiment carried out?

    • BoBBLE will deploy two ships, six ocean gliders and eight floats to collect an unprecedented range of oceanic and air-sea flux observations.
    • These will occupy locations in the southwest and southeast Bay, as well as tracing east-west and north-south paths between those locations, measuring ocean temperature, salinity and currents.

    With inputs from http://www.walker.ac.uk/research/projects/bay-of-bengal-boundary-layer-experiment-bobble/