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Subject: Science and Technology

  • [pib] UV Blaster: A UV Disinfection Tower

    The DRDO has developed an Ultra Violet (UV) Disinfection Tower for rapid and chemical-free disinfection of high infection-prone areas.

    GYAN:

    We have a UV filter in our home based water filter.  Ever wondered, how do UV rays kill viruses/bacteria?

    UV Blaster

    • The UV blaster is a UV based area sanitizer designed and developed by Laser Science & Technology Centre (LASTEC), the Delhi based premier laboratory of DRDO.
    • It is useful for high tech surfaces like electronic equipment, computers and other gadgets in laboratories and offices that are not suitable for disinfection with chemical methods.
    • The product is also effective for areas with a large flow of people such as airports, shopping malls, metros, hotels, factories, offices, etc.

    How does it work?

    • The UV based area sanitizer may be used by remote operation through laptop/mobile phone using wifi link.
    • The equipment has six lamps each with 43 watts of UV-C power at 254 nm wavelength for 360-degree illumination.
    • For a room of about 12 x 12 feet dimension, the disinfection time is about 10 minutes and 30 minutes for 400 square feet area by positioning the equipment at different places within the room.
    • This sanitizer switches off on the accidental opening of a room or human intervention.

    Back2Basics: UV germicidal irradiation

    • UV irradiation is a disinfection method that uses short-wavelength ultraviolet rays to kill or inactivate microorganisms by destroying nucleic acids and disrupting their DNA, leaving them unable to perform vital cellular functions.
    • UVGI is used in a variety of applications, such as food, air, and water purification.
    • UVGI devices can produce strong enough UVC light in circulating air or water systems to make them inhospitable environments to microorganisms such as bacteria, viruses, moulds, and other pathogens.
    • UVGI can be coupled with a filtration system to sanitize air and water.
    • It has been used primarily in medical sanitation and sterile work facilities.
    • Increasingly, it has been employed to sterilize drinking and wastewater since the holding facilities are enclosed and can be circulated to ensure a higher exposure to the UV.
  • Rethinking the role of Intellectual Property in Corona crisis

    The article discusses the idea of creating a patent pool of the patents dealing with Covid-19. Such a patent pool will be effective in avoiding the possibility of the hostile response of societies towards patent rights. And also avoid the conflict between nations. corporations and international organisations.

    Purpose of patent rights

    • The purpose of creating and recognising patent rights is for the common public good, i.e., innovation should be made public in exchange for a limited monopoly.
    • Thus, patents need to be disclosed to the public in order to enable further research.
    • Should pandemics such as COVID-19be an exception to this?
    • With the outbreak of COVID-19, there are several innovations.
    • All these innovations may be the subject matter of patent applications around the world.
    • It will be a few years before patents are even granted.
    • However, friction already exists among various stakeholders.
    • For instance, one country made attempts to obtain exclusive rights to a vaccine being developed.
    • On the other hand, there are also collaborations taking place.
    • However, the spirit of collaborative solutions is only on the anvil.
    • The question that arises is whether the exclusivity that is recognised by patent rights will be detrimental to society.
    • Will patents create roadblocks or is there a solution?

    Possibility of conflicts over patent rights

    • Governments and international organisations need to arrive at a consensus in advance to ensure that the system is ready.
    • Procrastination would be disastrous.
    • Creating hindrances through exclusivity claims, in the wake of a pandemic, will result in dividing countries, corporations and international organisations.
    • This will not benefit patients and the world as a whole.
    • If patent owners create impediments on the strength of patent rights, the world will start despising patents and that is not a situation IP owners ought to be in.
    • Under the TRIPS (Trade-Related Aspects of Intellectual Property Rights) regime, there are several tools such as compulsory licensing that are available to ensure access to medicines.
    • However, beyond the laws, society needs to respect innovation.
    • To protect the sanctity and integrity of patent systems, and in order to ensure that an anti-IP sentiment is not generated globally, answers need to be found within the existing regime.
    • In exceptional circumstances such as these, there is a likelihood that societies may resort to extreme steps to protect themselves.
    • Before such ideas are floated, solutions should be created.

    The idea of creating a patent pool

    • One method by which aggregation and dissemination of innovative products can be ensured is by creating a patent pool.
    • Patent pools are usually effective in aggregating, administering and licensing patents related to specific areas of technology.
    • Such pools are usually managed by a central agency and the patents which become part of the pool are readily made available for licensing.
    • Some pools even publish the royalty rates payable for such licences.
    • Anyone who wishes to obtain a licence will be able to approach the pool, agree to the terms, and begin to manufacture and sell the products.
    • Such pools are prevalent in, for instance, standard essential patents related to telecom and digital innovations.
    • At the moment, individual efforts are being made by research organisations to create their own pools.
    • A more fruitful endeavour would be to create a global pool of COVID-19-related innovations, or innovations related to rare pandemics, in respect of vaccines and medicines.
    • This could be managed by a trustworthy international organisation.
    • All countries ought to have the right to implement these innovations without further permission from the patent-holders.
    • This would not require countries resorting to provisions such as compulsory licensing, state acquisition, etc.
    • Even if royalties are at a minimal level, the revenues would still be in billions of dollars owing to the large swathes of the population affected by the pandemic, who will need to be administered these products.

    Way forward

    • Creation of a pool and immediate licensing will ensure that there are hundreds of manufacturers across the world.
    • As a result, vaccines and medicines will be quickly available.
    • Such a pool needs the cooperation of not just countries and international organisations but also the hundreds of researchers, innovators, companies and universities involved.
    • Doha Declaration: Pooling of patent resources is also in line with the Doha Declaration on Public Health which is a part of the TRIPS agreement.
    • This declaration recognises the need for taking measures to ‘protect public health’ and ‘promote access to medicines’.

    A direct question on the issue can be asked by the UPSC, for ex-“Though IPRs have been provided to respect and protect the innovations and ideas, but in the wake of corona crisis, some strict provisions need to be changed. In light of the above statement, discuss the limitations of the exclusivity clause under the patents rights. And how can it be overcome in emergency situations?”

    Conclusion

    Public-private partnerships (PPP) need to be scaled up. Creation of the ‘PPP-pandemic patent pool’ at a global level, to pool all innovations, is the way forward. Let us not wait any longer.

  • Plasma therapy is no silver bullet

    The article discusses the issues with convalescent plasma therapy. The therapy has been in the news as a cure to Covid-19. The lack of conclusive evidence is a major issue. There are certain risks involved in large scale adoption. All such issues are dealt with in detail here.

    Importance of scientific research in dealing with Covid-19

    • The COVID-19 pandemic has posed unprecedented challenges to governments, health professionals and the general public at large, around the world.
    • Every response, administrative, social, economic or medical is being subjected to intense public scrutiny, as it rightly should be in the spirit of mature democracy.
    • Scientific research in medicine is the only means to overcome novel and complex diseases such as COVID-19 and that too thrives on the same spirit of debate and criticism.
    • Difficulty in establishing protocols: The difference is that the standards of evidence required, to generate consensus and arrive at the most optimal protocols, are far more rigorous and time-taking than in most other walks of life.

    Issues with plasma therapy

    • The convalescent plasma therapy, that is being currently studied by the Indian Council of Medical Research, through open-label, randomised controlled trial to evaluate it for both safety and efficacy.
    • The problem with the therapy is of the lack of established protocols.
    • What is involved in therapy? The therapy involves infusing patients suffering from COVID-19 with plasma from recovered patients.
    • In theory, the antibodies of the recovered person may help that patient’s immune system fight the virus.
    • While showing great promise, it is a line of treatment that is yet to be validated for efficacy and safety and cannot be deployed widely without caution.
    • The current evidence to conclude anything about the true benefits of this therapy is very thin.
    • Till date, there have been only three published case series for convalescent plasma in COVID-19 with a cumulative of 19 patients.
    • Given the very small number of patients involved in these studies and a publication bias in medicine, we cannot conclude the therapy will work on all patients all the time or even believe that the convalescent plasma was the only reason for their improvement.
    • The most important principle in medical ethics is “do no harm”.
    • The transfusion of convalescent plasma is also not without risks, which range from mild reactions like fever, itching, to life-threatening allergic reactions and lung injury.
    • To recommend a therapy without studying it thoroughly with robust scientific methods may cause more harm than good.
    • Further, convalescent plasma therapy requires intensive resources, healthy COVID-19 survivors to donate, a blood bank with proper machinery and trained personnel to remove plasma, equipment to store it and testing facilities to make sure it has an adequate amount of antibodies.

    Need for the Randomised Controlled Trials (RCT)

    • To say with certainty whether a drug is truly effective or not, the gold standard in medicine is to conduct a randomised controlled trial.
    • In RCT half the patients get the experimental drug and the other half do not.
    • Only if patients in the first half show substantial improvement over those in the second half, it indicates the drug is beneficial.

    Exploring other options and focusing on health infrastructure

    • Too much focus on one approach can take away the focus from other important therapeutic modalities like the use of oxygen therapy, antivirals, and antibiotics for complicated hospital courses.
    • To overcome the pandemic comprehensively, we should focus on strengthening health systems at all levels, including referral systems, supply chain, logistics and inventory management.
    • We need to work on protecting our healthcare workers, improving prevention methods, promoting cough etiquettes, effective quarantining and accurate testing.

    A direct question based on the therapy like- “What is convalescent plasma therapy and what are the issues involved in its adoption?” can be asked by the UPSC.

    Conclusion

    Even these times of collective uncertainty are no reason to lower scientific temper. Science should be driven by reason and evidence with hope as a catalyst but not by either fear or populism. Pushing one or the other therapy without evidence or caution can only set back our larger fight against COVID-19.

  • [pib] Earth’s Magnetosphere and its dynamics

    Scientists at the Indian Institute of Geomagnetism (IIG) have developed a generalized one-dimensional fluid simulation code capable of studying a wide spectrum of coherent electric field structures of earth’s magnetosphere which can be useful in the planning of future space missions.

    The newscard talks of not so new phenomenon but a basic terminology of space sciences. Kindly make a note of what the Magnotesphere is, how it is formed, role of solar winds, Geodynamo etc.

    Earth’s Magnetosphere

    • The magnetosphere is the region of space surrounding Earth where the dominant magnetic field is the magnetic field of Earth, rather than the magnetic field of interplanetary space.
    • It is generated by the interaction of the solar wind with Earth’s magnetic field.

    Features of the Earth’s magnetosphere

    1) Bow shock,

    2) Magnetosheath,

    3) Magnetopause,

    4) Northern tail lobe,

    5) Southern tail lobe,

    6) Plasmasphere,

    7) Solar wind.

    How is it formed?

    • Sun is the major source of plasma deposition in space around the Earth. Sun forces some of its plasma towards the earth in the form of the solar wind.
    • The speed of this wind varies between 300 to 1500 km/s, which carries with it solar magnetic field, called as Interplanetary Magnetic Field (IMF).
    • The magnetic field is generated by electric currents due to the motion of convection currents of a mixture of molten iron and nickel in the Earth’s outer core.
    • These convection currents are caused by heat escaping from the core, a natural process called a geodynamo.

    Why study the magnetosphere?

    • The Earth’s magnetosphere is a vast region which has a finite number of satellites hurtling through this realm.
    • The morphology of the plasma processes around the satellite can be understood quite well.
    • However, when they leave the observational domain of one satellite to enter into another, a vast blind arena is created.
    • How the morphology of these processes changes over space and time can be ideally deciphered only through computer simulations.

    Outcome of the study

    • Almost 99% of matter in the universe is in the form of plasma, Earth’s magnetosphere, too, contains this material and the plasma.
    • They have the ability to hamper the working of a number of satellites that have been placed in orbit in the magnetospheric region.

    Significance

    • Apart from the well being of these expensive satellites, the academic understanding of this region is quite essential to comprehend the cosmos in its entirety.
    • The study will help advance the knowledge of plasma waves, instabilities, and coherent effects associated with wave-particle interactions that are useful in planning of future space missions.
    • It can also lead to precisely controlled fusion laboratory experiments for ever-expanding energy needs of humanity.
  • Festival in news: Chithirai Festival

    For the first time, in place of Madurai’s Chithirai Festival, a simple celestial union is set to take place that will be streamed online.

    Match the pair based question can be asked from festivals as such. Recently, the following festivals were in the news: Ambubachi Mela, Thrisoor Puram, Meru Jatara, Nagoba Jatara etc.

    Chithirai Festival

    • Chithirai Festival or Chithirai Thiruvizha is an annual celebration celebrated in the city of Madurai during the month of April.
    • It is celebrated during the Tamil month of Chithirai.
    • It lasts for one month of which the first 15 days mark the celebrations of the coronation of Goddess Meenakshi and the Marriage of Lord Sundareswara and Goddess Meenakshi.
    • The next 15 days mark the celebrations of the Journey of Lord Alagar from Kallazhagar temple in Alagar Koyil to Madurai.

    About Meenakshi Temple

    • The ancient city of Madurai, more than 2,500 years old, was built by the Pandyan king, Kulashekarar, in the 6th century B.C.
    • But the reign of the Nayaks marks the golden period of Madurai when art, architecture and learning flourished expansively.
    • The most beautiful buildings in the city including its most famous landmark, the Meenakshi temple, were built during the Nayak rule.
    • Located in the heart of the city, the Meenakshi-Sundareshwarar temple is dedicated to goddess Meenakshi, the consort of lord Shiva.
    • The sculpted pillars are adorned with the exquisite murals that celebrate the ethereal beauty of princess Meenakshi and the scenes of her wedding with Lord Shiva.
    • The pillars depict scenes from the wedding of Meenakshi and Sundareswarar. There are 985 richly carved pillars here and each one surpasses the other in beauty.
  • [pib] HCARD robot to assist frontline COVID-19 healthcare warriors

    HCARD, a robot, to assist frontline COVID-19 healthcare warriors has been developed by a CSIR lab.

    It is very unlikely to create a prelim question on HCARD. However, developments as such help in exemplifying the scientific developments which helped contain such highly contagious outbreaks.

    What is HCARD?

    • The robotic device HCARD, an acronym for Hospital Care Assistive Robotic Device, can help frontline healthcare workers in maintaining physical distance from those infected by the coronavirus.
    • The device is equipped with various state-of-the-art technologies and works both in automatic as well as manual modes of navigation.
    • This robot can be controlled and monitored by a nursing booth with a control station having such features as navigation, drawer activation for providing medicines and food to patients, sample collection and audio-visual communication.
    • The cost of this device is less than Rs 5 lakh and the weight is less than 80 kilograms.
  • Raja Ravi Varma, the painter who helped Indians bring their gods home

    April 29 is the birth anniversary of the famed Indian painter Raja Ravi Varma (1848-1906), remembered for giving Indians their western, classical representations of Hindu gods and goddesses.

    Raja Ravi Varma

    • Varma was born into aristocracy at Kilimanoor in the erstwhile Travancore state of present-day Kerala and was closely related to its royal family.
    • At the age of 14, Varma was patronised by Ayilyam Thirunal, the then ruler of Travancore, and went on to receive training in watercolours from Ramaswamy Naidu, the royal painter.
    • Later, Varma studied oil painting with the British painter Theodore Jensen.
    • Apart from Travancore, Varma also worked for other wealthy patrons such as the Gaekwad of Baroda.

    Major works

    • A prolific artist, Varma is believed to have made around 7,000 paintings before his death.
    • Varma worked on both portrait and landscape paintings and is considered among the first Indian artists to use oil paints.
    • Apart from painting Hindu mythological figures, Varma also made portraits of many Indians as well as Europeans.
    • His most famous works include Damayanti Talking to a Swan, Shakuntala Looking for Dushyanta, Nair Lady Adorning Her Hair, and Shantanu and Matsyagandha.

    His legacy

    • He continues to be regarded as the most important representative of the Europeanized school of painting in India.
    • His 1873 painting, Nair Lady Adorning Her Hair, won Varma prestigious awards including Governor’s Gold Medal when it was presented in the Madras Presidency and Certificate of Merit at an exhibition in Vienna.
    • In 1904, the British colonial government awarded Varma with the Kaiser-i-Hind Gold Medal.
    • In 2013, a crater on the planet Mercury was named in his honour.
  • Who was Lord Basaveshwara?

    Prime Minister has offered his homage to the 12th-century social reformer Basaveshwara on his birth anniversary.

    Vaishnavism and Shaivism are the two most profound strands of Bhakti Movement in Indian history. Enlist all the Bhakti Saints and their theistic philosophy and teachings. Try to spot the minute differences between them.

    Lord Basaveshwara

    • Basaveshwara or Basavanna was an Indian 12th-century statesman, philosopher, a poet and Lingayat saint in the Shiva-focussed Bhakti movement and a social reformer in Karnataka.
    • He lived during the reign of the Kalyani Chalukya/Kalachuri dynasty.
    • He was active during the rule of both dynasties but reached his peak of influence during the rule of King Bijjala II in Karnataka, India .

    Founder of Lingayat cult

    • The traditional legends and hagiographic texts state Basava to be the founder of the Lingayats.
    • However, modern scholarship relying on historical evidence such as the Kalachuri inscriptions state that Basava was the poet-philosopher who revived, refined and energized an already existing tradition.

    His Philosophy

    • Basava’s Lingayat theology was a form of qualified nondualism, wherein the individual Atman (soul) is the body of God, and that there is no difference between Shiva and Atman (self, soul).
    • Basava’s views finds places in Vedanta school, in a form closer to the 11th century Vishishtadvaita philosopher Ramanuja.

    Famous works

    • Basavanna spread social awareness through his poetry, popularly known as Vachanaas.
    • Basavanna rejected gender or social discrimination, superstitions and rituals but introduced Ishtalinga necklace, with an image of the Shiva Liṅga to every person regardless of his or her birth.
    • As the chief minister of his kingdom, he introduced new public institutions such as the Anubhava Mantapa (or, the “hall of spiritual experience”) which welcomed men and women from all socio-economic backgrounds.

    Back2Basics: Bhakti Movement

    • The Bhakti movement refers to the theistic devotional trend that emerged in medieval Hinduism.
    • It originated in eighth-century south India and spread northwards.
    • It swept over east and north India from the 15th century onwards, reaching its zenith between the 15th and 17th century CE.
    • It has traditionally been considered as an influential social reformation in Hinduism, and provided an individual-focused alternative path to spirituality regardless of one’s birth or gender
    • Salvation which was previously considered attainable only by men of Brahmin, Kshatriya and Vaishya castes, became available to everyone.
  • GW190412: The first merger of two black holes with unequal masses

    For the first time since it started functioning, the gravitational wave observatories at LIGO scientific collaboration have detected a merger of two unequal-mass black holes.

    This newscard contains few basic terms that one must know-

    Gravitational waves

    General Relativity

    Black Holes

    GW190412

    • The event, dubbed GW190412, was detected nearly a year ago, and this is almost five years after the first-ever detection of gravitational-wave signals by these powerful detectors.
    • Subsequent analysis of the signal coming from the violent merger showed that it involved two black holes of unequal masses coalescing.
    • One of them was some 30 times the mass of the Sun and the other which had a mass nearly 8 times the solar mass.
    • The actual merger took place at a distance of 2.5 billion light-years away.

    Significant feature observed

    • The detected signal’s waveform has special extra features in it when it corresponds to the merger of two unequal-sized black holes as compared with a merger of equal-sized black holes.
    • These features make it possible to infer many more things about the characters such as- a more accurate determination of the distance from the event, the spin or angular momentum of the more massive black hole and the orientation of the whole event with respect to viewers on Earth.
    • While the mass of the black hole bends the space-time close to it, the spin or angular momentum of this inscrutable object drags the nearby space-time, causing it to swirl around, along with it.
    • Hence both these properties are important to estimate.

    Confirmed General Relativity

    • An Indian team consisting of researchers verified the consistency of the signal with the prediction of General Relativity.
    • The existence of higher harmonics was itself a prediction of General Relativity.

    Must refer for an easy and illustrated understanding of General Relativity-

     

  • The Curie Family and its Nobel legacy

    This newscard is inspired by an article published in the DTE which talks about a family which has received a total of four Nobel prizes, the highest won by a single-family.

    Last year in 2019 CSP, there was a question on pure Biology about Hepatitis and its variants. With such news trending, we can expect a core chemistry or physics based question coupled with a slight Current Affairs blend.

    The ‘Nobel’ family

    • On April 20, 1902, Marie and Pierre Curie successfully isolated radioactive radium salts from pitchblende, a mineral, in a laboratory in Paris, France.
    • They were inspired by French physicist Henri Becquerel’s 1896 experiment on phosphorescence or the phenomenon that allows certain objects to glow in the dark.
    • They were able to find traces of two radioactive elements—polonium (Element 84) and radium (Element 88).
    • Curie shared the 1903 Nobel with her fellow researcher Pierre Currie and Becquerel for their combined work on radioactivity.

    Important facts

    • In 1903, Marie Curie received the Nobel Prize in Physics making her the world’s first woman to win the prize.
    • In 1911, she created history again by becoming the first woman to have won two Nobel awards.
    • The 1911 Nobel Prize in Chemistry was awarded to Marie after she managed to produce radium as a pure metal. This proved the new element’s existence beyond doubt.
    • However, this was not the last Nobel for the Curie family.
    • The 1935 Nobel in Chemistry went to Irène Curie and her husband and co-researcher Frédéric Joliot for their joint work on the artificial creation of new radioactive elements.
    • The Curies have received a total of four of Nobel prizes, the highest won by a single-family. They also have the unique distinction of having three Nobel-prize winning members in the family.

    Birth of Radioactivity

    • While delivering a lecture at the Royal Academy of Sciences in Stockholm, Sweden in 1911, Curie shared some critical details about “radioactive elements” and the phenomenon called “radioactivity”.
    • She also spoke about the chemical properties of radium, the new element that was about a million times more radioactive than uranium.
    • Radium in solid salts was about 5 million times more radioactive than an equal weight of uranium.

    Back2Basics: Radioactivity

    • Radioactivity refers to the particles which are emitted from nuclei as a result of nuclear instability.
    • It is the process by which an unstable atomic nucleus loses energy by radiation.
    • The most common types of radiation are called alpha, beta, and gamma radiation, but there are several other varieties of radioactive decay.
    • Radioactive decay rates are normally stated in terms of their half-lives, and the half-life of a given nuclear species is related to its radiation risk.
    • Examining the amounts of decay products makes possible radioactive dating.

    Its applications

    • Medical use: Many diseases such as cancer are cured by radiotherapy. Sterilization of medical instruments and food is another common application of radiation.
    • Scientific use: Alpha particles emitted from the radioisotopes are used for nuclear reactions.
    • Industrial use: Radioisotopes are used as fuel for atomic energy reactors. Also used in Carbon dating.