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Subject: Science and Technology

  • [pib] National Tuberculosis Elimination Programme (NTEP)

    Why in the News?

    The Union Ministry of Health has re-strategized the National Tuberculosis Elimination Programme (NTEP) under the 100-Day TB Elimination Campaign to reduce TB cases and mortality through targeted interventions and a multi-pronged approach.

    Menace of TB in India:

    • According to the World Health Organization (WHO), India accounted for 26% of global TB cases and deaths in 2023.
    • The Indian Council of Medical Research (ICMR) conducted a National TB Prevalence Survey in 20 states, reporting 312 TB cases per lakh population.
      • The TB incidence rate decreased by 17.7%, from 237 per 100,000 in 2015 to 195 per 100,000 in 2023.
      • Similarly, TB-related deaths have declined by 21.4%, from 28 per lakh population in 2015 to 22 per lakh population in 2023.

    About the National TB Elimination Programme (NTEP):

    Details
    About
    • Former Name: Revised National Tuberculosis Control Programme (RNTCP)
    • Objective: To eliminate tuberculosis (TB) as a public health issue in India by 2025, as per PM Modi’s 2018 target.
    • Focus Areas: Early detection, complete treatment, prevention, and strengthening TB care and control services.

    Key Components of NTEP:

    • Universal Drug Susceptibility Testing (UDST): Early detection of drug-resistant TB.
    • Free Diagnosis and Treatment: Provided for all TB patients across India.
    • Nikshay: A case-based web-enabled TB information system for monitoring and case management.
    • Private Sector Engagement: Involving private healthcare providers for standardized care.
    Objectives under the National Strategic Plan 100-Day TB Elimination Campaign is an intensified effort launched to fast-track the detection and treatment of tuberculosis (TB) cases across the country.

    • Eliminate TB as a public health problem by 2025.
    • Achieve Universal Access to quality TB care.
    • Prevent the emergence of drug-resistant TB through early diagnosis and appropriate treatment.
    • Reduce the burden of TB through preventive interventions and awareness campaigns.
    • Ensure better case management through Nikshay, a case-based monitoring system.
    • 6. Engage with the private sector to ensure standardized and quality TB care.
    Steps taken by Govt
    • Universal Drug Susceptibility Testing (UDST): Early detection of drug-resistant TB.
    • Free Diagnosis and Treatment: Provided for all TB patients.
    • Nikshay System: Web-enabled case-based monitoring and management system for TB patients.
    • Private Sector Engagement: Ensuring standardized TB care by involving private healthcare providers.
    • National TB Prevalence Survey: Conducted to assess the TB burden in 20 states.
    • Enhanced Diagnostic Facilities: Including genetic and molecular tests for early detection.
    • Targeted Interventions for Vulnerable Populations: Focus on high-risk groups, including children and marginalized populations.

  • Marburg Virus outbreak in Rwanda

    Why in the News?

    An outbreak of Marburg Virus (Bleeding Eyes) disease (MVD) has killed and infected many in Rwanda.

    rwanda
    Location of Rwanda

    About Marburg Virus:

    Overview • Causes Marburg Virus Disease (MVD), also known as Marburg Hemorrhagic Fever.
    • Belongs to the filovirus family (same as Ebola).
    • Discovered during outbreaks in 1967 in Marburg and Frankfurt, Germany.
    • Case Fatality Rate ranges from 24% to 88%, depending on the strain and treatment effectiveness.How does it spread?• Animal to Human Transmission: Spread primarily from Rousettus bats, especially Egyptian fruit bats found in caves or mines.
    • Human to Human Transmission: Spread through direct contact with blood and bodily fluids (saliva, vomit, feces, semen, and breast milk). Also transmitted indirectly through contaminated surfaces or clothing.
    Symptoms and Treatment • Early signs include fever, headache, muscle aches, chills, nausea, vomiting, and severe diarrhoea.

    • Progresses to bleeding from various body parts, and death typically occurs 8-9 days after symptoms due to blood loss and organ failure.
    • No approved vaccine or antiviral treatment. Supportive care includes hydration, symptom management, and blood transfusions. Experimental vaccines are being studied.
    Why is it a Global Concern? • High Fatality Rate: MVD’s case fatality rate (24%-88%) makes it one of the deadliest diseases.
    • Spread: Ongoing outbreaks, primarily in Africa, but now affecting Rwanda and Tanzania.
    • Public Health Threat: Human-to-human transmission and rapid spread pose significant challenges.
    • Economic Impact: Outbreaks disrupt local economies, healthcare systems, and global trade due to travel restrictions and quarantine measures.

     

    PYQ:

    [2015] Among the following, which were frequently mentioned in the news for the outbreak of Ebola virus recently?

    (a) Syria and Jordan

    (b) Guinea, Sierra Leone and Liberia

    (c) Philippines and Papua New Guinea

    (d) Jamaica, Haiti and Surinam

  • ecDNA Challenges Law of Genetics

    Why in the News?

    A recent study published in the ‘Nature’ has shown that Extrachromosomal DNA (ecDNA) is present in approximately 50% of cancer types, playing a significant role in tumor evolution and genetic heterogeneity.

    What is ecDNA?

    Details • ecDNA stands for extrachromosomal DNA, which is small, circular DNA found in the nucleus of cells, separate from regular chromosomes.
    • Forms when DNA breaks off from chromosomes, often due to damage or errors in cell division.
    • Can carry extra copies of oncogenes, which promote cancer growth.
    • Initially thought to be unimportant, recent studies show it plays a major role in cancer.
    How ecDNA Contributes to Cancer and Drug Resistance • Helps Tumors Grow: ecDNA contains extra copies of oncogenes that help cancer cells grow faster and become more aggressive.
    • Drug Resistance: The extra oncogenes make the cancer harder to treat with standard drugs by producing more harmful proteins.
    • Faster Tumor Evolution: ecDNA allows cancer cells to evolve rapidly, making them more resistant to treatments like chemotherapy and enabling the tumor to grow even when drugs are used.

     

    How ecDNA Challenges Genetics Laws?

    • Mendel’s Law says that genes on different chromosomes are inherited independently, meaning they are passed on randomly to the next generation.
    • ecDNA breaks this rule by grouping genes together and passing them on as a cluster during cell division.
    • This allows cancer cells to inherit beneficial genes more easily and helps the tumor grow faster.
    • Unlike regular chromosomes, which are distributed randomly during cell division, ecDNA is passed on together as a package.
    • This process gives cancer cells an advantage by making sure they inherit helpful genetic combinations that support cancer growth and resistance to drugs.

  • What India’s AI Safety Institute could do?

    Why in the News?

    In October, the Ministry of Electronics and Information Technology (MeitY) held discussions with industry leaders and experts about establishing an AI Safety Institute as part of the IndiaAI Mission.

    What are the core objectives and focus areas for the AI Safety Institute?

    • Setting Standards for AI Safety: The AISI aims to develop frameworks, guidelines, and standards for safe AI deployment without acting as a regulatory body. This approach is designed to foster innovation while ensuring safety.
    • Enhancing Domestic Capacity: The institute will focus on building domestic capabilities in AI safety, leveraging India’s unique strengths and addressing local challenges related to AI deployment.
    • Promoting Multi-Stakeholder Collaboration: Engaging various stakeholders—including government bodies, industry players, academia, and civil society—is crucial for creating a comprehensive approach to AI safety that reflects diverse perspectives.
    • Risk Assessment and Mitigation: The AISI will develop tools for risk assessment and mitigation related to AI technologies, focusing on issues such as bias, discrimination, and social exclusion.
    • Global Engagement: By integrating into international networks like the Bletchley Process, the AISI will participate in global dialogues on AI safety, bringing forward the concerns of developing countries and contributing to a more inclusive governance framework.

    How should the organizational structure of the AISI be designed to ensure scalability and independence?

    • Independence from Regulatory Bodies: The AISI should operate independently from rulemaking and enforcement authorities to maintain its focus on research, testing, and standardization rather than regulatory compliance.
    • Collaboration with Academic Institutions: Establishing the AISI within academic institutions (e.g., IITs) can provide it with a degree of independence while tapping into existing research capabilities and expertise.
    • Scalable Framework: The organizational structure should be designed for scalability, allowing the institute to adapt to evolving technological landscapes and increasing demands for AI safety oversight.
    • Technical Research Focus: The AISI should prioritize technical research and development of indigenous AI safety tools that address India’s specific challenges while aligning with global standards.

    What strategies can be implemented to engage stakeholders and build partnerships for effective AI safety governance? (Way forward)

    • Building Strong Partnerships: The AISI should actively seek partnerships with key stakeholders in government, industry, academia, and civil society both nationally and internationally to foster collaboration on AI safety initiatives.
    • Engaging in Global Dialogues: Participation in international forums and dialogues on AI governance will help position India as a leader in global discussions on AI safety, allowing for knowledge exchange and shared best practices.
    • Community Involvement: Engaging local communities through outreach programs can raise awareness about AI risks and promote inclusive participation in shaping AI governance policies.
    • Establishing Voluntary Compliance Tools: Developing voluntary compliance toolkits can help industries adopt best practices in AI safety without imposing stringent regulatory requirements that could stifle innovation.
    • Continuous Feedback Mechanisms: Implementing mechanisms for continuous feedback from stakeholders will ensure that the AISI remains responsive to emerging challenges in AI technology and governance.

    Mains PYQ:

    Q  What are the main socio-economic implications arising out of the development of IT industries in major cities of India? (UPSC IAS/2021)

  • [pib] Asia-Oceania Meteorological Satellite Users’ Conference (AOMSUC-14)

    Why in the News?

    The 14th Asia-Oceania Meteorological Satellite Users’ Conference (AOMSUC-14) will take place from December 4-6, 2024, in New Delhi.

    About AOMSUC:

    Details
    What is it? • It is a conference focused on the use of meteorological satellite data for weather forecasting, climate monitoring, and disaster risk management.
    • First AOMSUC was held in Beijing, China in 2010.• Held annually across various locations in the Asia-Oceania region, becoming a significant event for meteorological satellite applications.

    • Participants: WMO, NASA, ESA, JAXA, and other leading space organizations.
    Aims and Provisions • Collaboration: Facilitate regional cooperation in the use of satellite data.
    • Weather & Climate Monitoring: Improve forecasting and monitoring of climate patterns.
    • Disaster Management: Enhance early warning systems for extreme weather events.
    • Capacity Building: Provide training, workshops, and knowledge-sharing opportunities for local meteorologists and satellite data users.
    • Data Sharing: Promote satellite data sharing across countries.
    Significance • Regional Cooperation: Promotes stronger collaboration between Asia-Oceania countries, helping to address shared meteorological challenges.
    • Improved Forecasting: Facilitates the improvement of satellite data usage for more accurate weather forecasts and better disaster risk reduction strategies.

  • [pib] National AYUSH Mission (NAM)

    Why in the News?

    • The National AYUSH Mission (NAM) is an important Centrally Sponsored Scheme aimed at promoting and developing the AYUSH systems of medicine across the country.
      • In addition to NAM, Central Sector Schemes like the AYURSWASTHYA Yojana and the AYURGYAN Scheme play a crucial role in advancing the mission’s objectives

    About AYURGYAN and AYURSWATHYA Scheme

    Details
    AYURSWASTHYA Yojana • Under the Ministry of AYUSH to promote AYUSH healthcare and education.
    • Has two key components:

    1. AYUSH and Public Health: Promotes AYUSH interventions for community health care.
    2. Upgradation of Facilities to Centre of Excellence: Improves standards of AYUSH medical units and establishes advanced centers in AYUSH and Allopathic institutions (both Govt. and Private).

    • Funding: Maximum assistance of ₹10 crore for Centre of Excellence upgrades for 3 years.
    AYURGYAN Scheme • Created by merging two schemes under one umbrella.
    • Focuses on promoting AYUSH education and research.
    • Aims to develop quality standards and expand AYUSH education and healthcare services across India.
    • Training of healthcare professionals in AYUSH and supporting research initiatives to improve efficacy and standards of traditional medicine.

    Back2Basics: National AYUSH Mission (NAM)

    Category Details
    Overview   • Launched in September 2014 under the Ministry of Health and Family Welfare during the 12th Five Year Plan.
    • Aimed at promoting and strengthening traditional systems of medicine: AYUSH (Ayurveda, Yoga, Unani, Siddha, Homeopathy).
    • Focuses on improving healthcare infrastructure in rural and remote areas, enhancing access to AYUSH services and promoting holistic health across India.
    Implementation and Structure • Initially implemented by the Department of AYUSH, now under the Ministry of AYUSH for nationwide execution.
    • Works in partnership with States and UTs to address healthcare gaps in underserved areas.
    Provisions under NAM • Promotion of AYUSH Systems: Integrates AYUSH into the mainstream healthcare system, especially in rural and underserved areas.
    • Support to State/UTs: Provides financial support for establishing AYUSH dispensaries, clinics, colleges and hospitals.
    • Strengthening AYUSH Health Services: Financial assistance for expanding AYUSH services, especially in remote areas.
    • Research & Development (R&D): Supports research for developing better treatments and standardizing practices in AYUSH.

    PYQ:

    [2019] How is the Government of India protecting traditional knowledge of medicine from patenting by pharmaceutical companies?

  • [pib] Schemes Implemented in Science and Technology

    Why in the News?

    The Ministry of Science and Technology, through its three key departments — Department of Science and Technology (DST), Department of Biotechnology (DBT), and Department of Scientific and Industrial Research (DSIR) — is implementing various schemes to bolster the Science, Technology, and Innovation (STI) ecosystem across India.

    Schemes Implemented Under the Department of Science and Technology (DST)

    Scheme   Objective Key Components
    Science and Technology (S&T) Institutional and Human Capacity Building (2015) Enhance human resource development and institutional capacity in science and technology. – Fellowships at various levels (undergraduate, postgraduate, doctoral, post-doctoral).
    – Establishment of sophisticated R&D facilities.
    – Capacity building for faculty.
    Research and Development (R&D) (2009) Support research in fundamental, applied, and translational sciences. – Collaborative research with universities, government, and private sectors.
    – International research cooperation.
    – Focus on diverse sectors like health, energy, and IT.
    Innovation, Technology Development, and Deployment (2016) Foster innovation and facilitate the development of new technologies for national development. – Technology incubation centers.
    – Technology transfer and commercialization.
    – Support for startups and entrepreneurs.
    National Mission on Interdisciplinary Cyber Physical Systems (NM-ICPS) (2017) Promote interdisciplinary research in Cyber Physical Systems (CPS) that integrate computational algorithms with physical processes. – Development of CPS technologies (e.g., IoT, smart cities, advanced manufacturing).
    – Setting up innovation centers and testbeds for CPS.
    National Quantum Mission (NQM) (2023) Advance quantum technologies for solving national challenges in energy, communications, and security. – Research in quantum computing, quantum communications, and quantum sensing.
    – Establishment of quantum technology hubs and research centers.

     

    Schemes Implemented Under the Department of Biotechnology (DBT)

    Scheme Objective Key Components
    Biotechnology Research Innovation and Entrepreneurship Development (Bio-RIDE) (2017) Foster innovation in biotechnology through research, industrial development, and entrepreneurship. – Biotechnology R&D: Funding for research projects.
    – Industrial & Entrepreneurship Development (I&ED): Support for biotech startups and industrial innovations.
    – Biomanufacturing and Biofoundry: Development of manufacturing and biotechnological production systems.

  • Major Atmospheric Cherenkov Experiment (MACE) Telescope

    Why in the News?

    The Major Atmospheric Cherenkov Experiment (MACE) telescope was inaugurated on October 4th in Hanle, Ladakh.

    About MACE Telescope:

    Details
    Details and Working • World’s highest imaging Cherenkov telescope, located in Hanle, Ladakh, at 4.3 km above sea level.
    • It has a 21-meter-wide mirror-dish, the largest in Asia.
    • Developed by Bhabha Atomic Research Centre (BARC), Tata Institute of Fundamental Research (TIFR), Electronics Corporation of India Ltd. (ECIL), and Indian Institute of Astrophysics (IIA).
    • Cherenkov radiation is captured using mirrors and analyzed with photomultiplier tubes (PMTs). Cherenkov radiation is the blue glow emitted when charged particles travel faster than light in a medium.
    • Equipped with a high-resolution camera and movable base.
    Aims and Objectives of MACE • Detects high-energy gamma rays (greater than 20 giga-electron volts) emitted by cosmic phenomena.
    • Detect Weakly Interacting Massive Particles (WIMPs) for dark matter research.
    • Contribute to multi-messenger astronomy by complementing data from other telescopes.
    How Do Gamma Rays Work in DNA Mutation? • Cause ionization, which can break chemical bonds in DNA, leading to mutations.
    • Mutations may result in cancers or genetic disorders if not repaired.
    • DNA damage from gamma rays can lead to chromosomal aberrations and contribute to carcinogenesis.

     

    PYQ:

    [2015] In the context of modern scientific research, consider the following statements about ‘IceCube’, a particle detector located at South Pole, which was recently in the news:

    1. It is the world’s largest neutrino detector, encompassing a cubic kilometre of ice.
    2. It is a powerful telescope to search for dark matter.
    3. It is buried deep in the ice.

    Which of the statements given above is/are correct?

    (a) 1 only

    (b) 2 and 3 only

    (c) 1 and 3 only

    (d) 1, 2 and 3

  • [pib] India’s first modern Compressed Biogas (CBG) Plant

    Why in the News?

    PM Modi inaugurated the 100 TPD cattle dung-based Compressed Bio-Gas (CBG) plant in Gwalior.

    About the CBG Plant 

    • The plant is located in Laltipara, Gwalior, within the largest cowshed in the region, Adarsh Gaushala, which houses over 10,000 cattle.
      • It spans over 5 acres.
      • It is India’s first self-sufficient gaushala with a modern CBG plant, where cow dung and organic waste (such as vegetable and fruit waste from mandis and households) are processed into valuable biogas.
    • The project, developed at a cost of ₹31 crores, is a collaboration between Gwalior Municipal Corporation and the Indian Oil Corporation.

    Working features:

    • Bio CNG: The plant produces 2 tons of compressed Bio CNG daily from 100 tons of cattle dung, providing a cleaner, eco-friendly alternative to traditional fossil fuels.
    • Organic Manure: The plant also generates 10-15 tons of dry bio-manure daily, which is a valuable by-product for organic farming.
    • Windrow composting: The plant incorporates windrow composting, located adjacent to the main facility, which enhances organic waste processing.

     

    What is Compressed Biogas (CBG)?

    Details
    About
    • CBG is a renewable natural gas produced from the biochemical conversion of organic waste into methane.
    • It is chemically similar to CNG (compressed natural gas) and can be used as an alternative to fossil fuels in transportation, cooking, and power generation.
    Process of Making CBG
    1. Collection of Organic Waste: Organic waste such as agricultural residue, animal dung, food waste, and municipal solid waste is collected from farms, industries, and households.
    2. Anaerobic Digestion: Waste is placed in an airtight chamber, where microorganisms break it down without oxygen, producing biogas (methane, carbon dioxide, trace gases).
    3. Purification: The raw biogas undergoes purification through methods like pressure swing adsorption, water scrubbing, or membrane separation to remove impurities like CO₂, H₂S, and water, leaving pure methane.
    4. Compression: The purified methane is compressed to 200-250 bar pressure to form CBG, reducing volume for storage and transportation.
    5. Storage and Distribution: It is stored in high-pressure cylinders or tanks and transported to fuel stations or industries for various applications.
    Significance of CBG
    • Reduces fossil fuel dependence.
    • Mitigates landfill methane emissions.
    • CBG can replace CNG, reducing pollution.
    • Utilizes local organic waste.
    • Creates jobs, promotes organic farming, and provides eco-friendly fertilizers.

  • Democratising AI needs a radically different approach

    Why in the News?

    Policymakers globally are addressing Big Tech’s dominance in AI by investing in sovereign cloud infrastructure, open data platforms, and supporting start-ups, yet these measures may inadvertently reinforce Big Tech’s control.

    How can we ensure that AI is implemented in a way that upholds democratic values?

    • It promotes Open Data Initiatives: While open data can enhance AI systems, it must be safeguarded against commercial capture by larger entities. Initiatives should focus on making data accessible and usable for smaller players without allowing Big Tech to monopolize it.
    • It invests in Public Compute Infrastructure: Establishing public computing resources can provide alternatives to private cloud services dominated by Big Tech. However, these resources must be competitive in terms of cost and functionality to be effective.
    • It fosters Smaller AI Models: Shifting focus from large-scale deep learning models to smaller, theory-driven AI models can democratize development. This approach emphasizes domain expertise and lived experiences over sheer data volume, which aligns better with democratic values.

    What role should public participation play?

    • Engagement in Policy Development: Involving diverse stakeholders, including community representatives and industry experts, can help create policies that reflect a broader range of interests and concerns regarding AI deployment.
    • Transparency and Accountability: Mechanisms should be established to ensure transparency in AI decision-making processes. Public oversight can help hold organizations accountable for their AI practices, particularly regarding data usage and algorithmic biases.
    • Community-Centric AI Solutions: Encouraging local communities to participate in the design and implementation of AI solutions can lead to more equitable outcomes. This involvement ensures that AI applications address specific community needs rather than serving corporate interests alone.

    What are the risks associated with technocratic governance?

    • Concentration of Power: The dominance of Big Tech can lead to a concentration of power where a few entities dictate the terms of AI development and deployment. This scenario risks sidelining smaller players and reducing diversity in innovation.
    • Surveillance and Privacy Concerns: The use of AI for surveillance by powerful corporations can threaten individual privacy rights. Policymakers must carefully consider the implications of deploying AI technologies that could exacerbate existing inequalities or infringe on civil liberties.
    • Erosion of Public Trust: If the public perceives that AI governance is primarily driven by technocratic elites without adequate input from citizens, trust in these systems may erode. This distrust can hinder the effective implementation of AI technologies that could otherwise benefit society.

    Way forward: 

    • Establish Inclusive AI Governance: Create multi-stakeholder frameworks involving governments, communities, and smaller players to ensure transparency, accountability, and equitable access to AI resources, safeguarding against monopolistic practices.
    • Prioritize Ethical, Small-Scale AI Development: Shift focus from large-scale deep learning models to theory-driven, domain-specific AI solutions that respect privacy, foster community involvement, and address localized needs, promoting democratic values in AI deployment.

    Mains PYQ:

    Q The emergence of the Fourth Industrial Revolution (Digital Revolution) hasinitiated e-Governance as an integral part of government”. Discuss. (UPSC IAS/2020)