💥UPSC 2026, 2027, 2028 UAP Mentorship (March Batch) + Access XFactor Notes & Microthemes PDF

Type: Prelims Only

  • Tex-RAMPS Scheme

    Why in the News?

    The Government of India approved a new scheme called Tex-RAMPS to strengthen research, data systems, innovation, and competitiveness in India’s textiles sector.
    The scheme aligns with India’s push to make its textiles ecosystem future-ready, technologically advanced, and globally competitive.

    What is Tex-RAMPS?

    Tex-RAMPS = Textiles Focused Research, Assessment, Monitoring, Planning and Start-up Scheme. It is a Central Sector Scheme, fully funded by the Ministry of Textiles.

    Outlay & Duration

    • Total Outlay: ₹305 crore
    • Period: FY 2025-26 to FY 2030-31
    • Co-terminus with the upcoming Finance Commission cycle

    Objectives

    To future-proof India’s textiles & apparel (T&A) ecosystem by:

    • Strengthening research and innovation
    • Building robust data systems
    • Enhancing global competitiveness
    • Supporting start-ups
    • Improving capacity development across the sector
    Atal Innovation Mission is set up under the (2019)

    (a) Department of Science and Technology 

    (b) Ministry of Employment 

    (c) NITI Aayog 

    (d) Ministry of Skill Development and Entrepreneurship

  • New Species of Plants and Animals Discovered

    Grey Seal Milk Complexity  

    Why in the News?

    A study published in Nature (Nov 2025) found that grey seal milk contains 332 different oligosaccharides33% more than human breast milk, previously considered the most complex.

    Key Findings

    Highest Oligosaccharide Diversity

    • Grey seal milk contains 332 oligosaccharides
      (Human milk: ~100).
    • This is the largest number ever recorded in any mammal’s milk.

    Functions of Oligosaccharides

    • Boost immunity (protect against bacteria & viruses).
    • Support gut microbiome formation.
    • Aid digestive tract development.
    • Provide energy and growth support for pups.

    Why Grey Seal Milk is So Complex?

    • Grey seals:
      • Live in harsh, high-risk environments.
      • Mothers fast for ~18 days while feeding pups.
      • Pups grow extremely rapidly during this period.
    • Complex sugars help pups survive extreme conditions and develop strong immunity quickly.

    Study Details

    • Conducted by the University of Gothenburg (Sweden).
    • Samples collected from Atlantic grey seals on a small Scottish island.
    • Analytical method used: Deep mass spectrometry.
      • A very advanced method of mass spectrometry that can detect hundreds to thousands of molecules in a sample with very high accuracy.
    Consider the following: 

    1. Bats 

    2. Bears 

    3. Rodents 

    The phenomenon of hibernation can be observed in which of the above kinds of animals? 

    (a) 1 and 2 only 

    (b) 2 only 

    (c) 1, 2 and 3 only 

    (d) Hibernation cannot be observed in any of the above

    This PYQ is chosen because it directly addresses the peculiar biological feature (hibernation) that allows mammals to survive challenging environmental conditions, which conceptually mirrors the adaptive features of the grey seal

  • Health Sector – UHC, National Health Policy, Family Planning, Health Insurance, etc.

    Aloe vera Compounds as Potential Alzheimer’s Inhibitors  

    Why in the news?

    A new study (Current Pharmaceutical Analysis, 2025) suggests that common plant molecules from Aloe vera—especially Beta sitosterol—may inhibit key enzymes associated with Alzheimer’s disease (AD). Findings are based entirely on in silico (computer simulation) techniques.

    What is Computer Simulation (In Silico Research)?

    • Computer simulation, often called in silico research, refers to the use of computational tools and algorithms to model biological, chemical, or physical processes.
    • It allows scientists to predict molecular interactions, drug behavior, and biological outcomes without physical experiments.

    Alzheimer’s Disease (AD) 

    • Most common form of dementia.
    • Characterised by:
      • Memory loss
      • Cognitive decline
      • Accumulation of beta-amyloid plaques and tau tangles
      • Loss of acetylcholine, a neurotransmitter linked to learning and memory.
    • Enzymes involved in acetylcholine breakdown:
      • Acetylcholinesterase (AChE)
      • Butyrylcholinesterase (BChE)
    • Current drugs (e.g., donepezil, rivastigmine) work by inhibiting these enzymes but do not stop disease progression.

    Why Aloe vera?

    • Used for 3000+ years in traditional medicine.
    • Contains bioactive compounds such as Beta sitosterol, Succinic acid, polysaccharides, and phenolics.

    Major Findings

    • Beta sitosterol showed strong binding affinity to both enzymes:
      • AChE: −8.6 kcal/mol
      • BChE: −8.7 kcal/mol
    • The binding strength is higher than that of other screened compounds like Succinic acid.
    • ADMET results suggest:
      • Good absorption
      • Low toxicity
      • Favourable pharmacokinetic profile
    Which one of the following is the context in which the term “qubit” is mentioned? (2022)

    (a) Cloud Services 

    (b) Quantum Computing 

    (c) Visible Light Communication Technologies 

    (d) Wireless Communication Technologies

    This PYQ is chosen because it tests a fundamental concept related to the cutting edge of computational power and modelling, which is the operational domain of computer simulation.

  • Health Sector – UHC, National Health Policy, Family Planning, Health Insurance, etc.

    Vitamin B12 Deficiency & Skin Manifestations 

    Why in the news?

    According to a study published in Canad­ian Family Physician, Vitamin B12 deficiency often shows early dermatological symptoms—such as pigmentation, dryness, and inflammation—before neurological or hematological complications appear.

    What is Vitamin B12?

    • Water-soluble vitamins are essential for: Red blood cell formation, Nerve function, DNA synthesis and Cell growth and repair

    Why Skin Shows Early Signs?

    • B12 deficiency → reduced RBC production → low oxygen delivery to skin → visible skin changes.
    • Weak immunity and impaired nerve function further worsen dermatological issues.
    High-Risk Groups

    More prone to Vitamin B12 deficiency:

    • Vegetarians/vegans
    • Adults > 50 years
    • Individuals with:
      • Gastritis, Crohn’s disease, celiac disease
    • Those taking:
      • Antacids (PPIs/H2 blockers)
      • Metformin
    • People with poor nutrient absorption
    Consider the following pairs: Vitamin : Deficiency disease (2014)

    1. Vitamin C : Scurvy 

    2. Vitamin D : Rickets 

    3. Vitamin E : Night Blindness 

    Which of the pairs given above is/are correctly matched? 

    (a) 1 and 2 only (b) 3 only (c) 1, 2 and 3 only (d) None

  • Solar Energy – JNNSM, Solar Cities, Solar Pumps, etc.

    International Astronomical Union (IAU) 

    Why in the news?

    • A 3.5-billion-year-old Martian crater has been named after Indian geologist M.S. Krishnan. The naming was approved by the International Astronomical Union (IAU).
    • Several other names proposed by Kerala scientists for Martian landforms were also approved.

    About the Martian Crater

    • Estimated to be 3.5 billion years old, dating back to Mars’ early geological history.
    • Located in a region studied for traces of ancient water and habitability.

    Who Was M.S. Krishnan?

    • Full name: Maharajapuram Seetharaman Krishnan
    • One of India’s most influential geologists, known as a foundational figure in modern Indian geological studies.
    • Served as Director, Geological Survey of India (GSI) (1950–1956).

    Major Contributions

    • Mapped India’s geological structures, including:
      • Indian stratigraphy
      • Peninsular shield
      • Himalayan formations
    • Played a leading role in mineral exploration and petroleum geology in India.
    • Contributed to studies on:
      • Gondwana formations
      • Economic geology
      • Earth resources of India

    Famous Work

    • Author of the landmark textbook “Geology of India and Burma”, a globally referenced work in earth sciences.

    About the International Astronomical Union (IAU)

    • Founded: 1919
    • A senior international body that governs professional astronomical activities worldwide.
    • Mission: Promote and safeguard astronomy through research, communication, education, development, and international cooperation.
    • Headquarters: Paris, France
    • India is a member of it 
    What is the purpose of ‘evolved Laser Interferometer Space Antenna (ELISA)’ project? (2017)

    (a) To detect neutrinos 

    (b) To detect gravitational waves 

    (c) To detect the effectiveness of missile defence system 

    (d) To study the effect of solar flares on our communication systems

    This PYQ is selected because it directly tests knowledge of a major international scientific venture in the field of astronomy/cosmology, which is conceptually linked to the mandate of the IAU

  • Skilling India – Skill India Mission,PMKVY, NSDC, etc.

    Entrepreneur-in-Residence (EIR) Programme & BRIC  

    Why in the news? 

    At the 3rd Annual General Meeting of the Biotechnology Research and Innovation Council (BRIC), Union Minister Dr. Jitendra Singh highlighted the growing importance of the Entrepreneur-in-Residence (EIR) Programme and India’s rising biotech innovation ecosystem.

    Entrepreneur-in-Residence (EIR) Programme

    • It is one of the programmes launched under the National Initiative for Developing and Harnessing Innovations (NIDHI).
    • A Government of India initiative to bridge the gap between research and enterprise.
    • Encourages young scientists, innovators, and researchers to become scientist-entrepreneurs.
    • Helps convert lab research → market-ready innovations.

    About BRIC

    • Established: 2023
    • Type: Pan-India umbrella network of biotechnology research institutions.
    • First major experiment in merging multiple institutes under one collaborative body.
    • Ranked as India’s top organization in biological sciences research (Nature Index India 2025).
    Which of the following statements is/are correct regarding National Innovation Foundation India (NIF)? (2015)

    (1) NIF is an autonomous body of the Department of Science and Technology under the Central Government. 

    (2) NIF is an initiative to strengthen the highly advanced scientific research in India’s premier scientific institution in collaboration with highly advanced foreign scientific institution. 

    Select the correct answer using the code given below. 

    (a) 1 only (b) 2 only (c) Both 1 and 2 (d) Neither 1 nor 2

  • Tribes in News

    Israel to Bring Remaining 5,800 Bnei Menashe Jews From Northeast India

    Why in the news?

    • On 23 November 2025, Israel approved a major plan to bring all remaining 5,800 members of the Bnei Menashe Jewish community from Northeast India by 2030.
    • This marks a significant step in the decades-long Aliyah (immigration to Israel) process.

    Who are the Bnei Menashe?

    • Indigenous community from Manipur and Mizoram.
    • Claim descent from Menashe (Manasseh), one of the Ten Lost Tribes of Israel exiled by the Assyrian Empire ~2,700 years ago.
    • Faced historical disputes over their Jewish identity.
    • In 2005, Rabbi Shlomo Amar, the then Sephardi Chief Rabbi of Israel, formally recognised them as “descendants of Israel”, enabling immigration.
    In India, if a religious sect/community is given “the status of a national minority, what special advantages is it entitled to? (2011)

    1. It can establish and administer exclusive educational institutions. 

    2. The President of India automatically nominates a representative of the community to Lok Sabha. 

    3. It can derive benefits from the Prime Minister’s 15-Point Programme. 

    Which of the statements given above is/are correct? 

    (a) 1 only (b) 2 and 3 only (c) 1 and 3 only (d) 1, 2 and 3

  • New Species of Plants and Animals Discovered

    Hawfinch Sighting in Jim Corbett National Park  

    Why in the news?

    • A Hawfinch (Coccothraustes coccothraustes), a bird species native to Europe, North Africa, and temperate Asia, was recorded on 23 November in the Dhela zone of Jim Corbett National Park, Uttarakhand. This is considered a vagrant bird sighting.

    About Hawfinch (Coccothraustes coccothraustes)

    • Family: Fringillidae (Finches)
    • Size: ~18 cm
    • Wingspan: 29–33 cm
    • Distinctive Feature: Very powerful, heavy bill capable of cracking extremely hard seeds/nuts.
    • Plumage: Males and females similar; males slightly darker.

    Native Range

    • Europe and North Africa
    • Temperate Asia, including:
      • Mongolia and Kazakhstan
    • Not native to India.

    Status in India

    • Sighting classified as a vagrant record—bird appears outside its usual distribution range.
    • Only two previous records in the Indian subcontinent:
      • Muzaffarabad (1908) – PoK
      • Aliabad (2017) – PoK
    • This is one of the very few confirmed sightings.
    Why is a plant called Prosopis juliflora often mentioned in the news? (2018) 

    (a) Its extract is widely used in cosmetics. 

    (b) It tends to reduce the biodiversity in the area in which it grows

    (c) Its extract is used in the synthesis of pesticides

    (d) None of the above

    This question tests the critical concept of non-native or exotic species impacting biodiversity, which is the implicit environmental concern raised by the Hawfinch sighting.

  • Water Management – Institutional Reforms, Conservation Efforts, etc.

    Mekedatu Balancing Reservoir Project

    Why in the news?

    • Karnataka has decided to submit a revised Detailed Project Report (DPR) for the Mekedatu balancing reservoir across the Cauvery River.
    • The Supreme Court termed Tamil Nadu’s challenge as “premature”, enabling the CWMA and CWC to examine the project.

    Location & River

    • Mekedatu is located in Ramanagara district, ~100 km from Bengaluru.
    • The project is proposed on the inter-State Cauvery river.
    • Karnataka = upper riparian; Tamil Nadu = lower riparian.

    Why Does Karnataka Want It?

    • Bengaluru water demand:
      • Present: 2,600 MLD
      • Supply: 2,100 MLD → shortage of 500 MLD
    • Population to reach 20 million in 6 years → demand may rise to 4,000 MLD.
    • Shivakumar argues Mekedatu will ensure regulated release to Tamil Nadu, even in poor rainfall years.

    Why Is Tamil Nadu Opposed?

    • Trust deficit due to the history of Cauvery disputes.
    • Concern: Karnataka may store more water and release it selectively.
    • TN argues the project violates the 2018 SC judgment and Cauvery Tribunal’s final award.

    Centre’s Position

    • 2019: Karnataka submitted DPR → CWC → CWMA.
    • MoEFCC (2019): Sought an “amicable solution” due to inter-State dispute.
    • 2024 (Feb): CWMA referred DPR back to CWC after deliberations.
    • Now: DPR to be examined afresh; CWMA/CWC can facilitate dialogue.

    Constitutional & Legal Angle

    • Inter-State Rivers: Union List Entry 56 – regulation and development of inter-State rivers.
    • River Boards Act, 1956 (not effectively implemented).
    • Cauvery Water Disputes Tribunal (CWDT): Award notified in February 2013.
    • Supreme Court Judgment (2018):
      • Reallocated shares;
      • Gave 4.75 TMC drinking water allocation to Bengaluru.

     

    Recently, linking of which of the following rivers was undertaken? (2016)

    (a) Cauvery and Tungabhadra 

    (b) Godavari and Krishna 

    (c) Mahanadi and Son 

    (d) Narmada and Tapti

  • Bastar Olympics

    Why in the news? 

    • The Bastar Olympics is a government-led sporting initiative in Chhattisgarh’s Bastar region, an area historically affected by Left-Wing Extremism (LWE).
    • It has become a symbol of normalisation, trust-building, and socio-cultural revival as Maoist influence recedes.

    What are the Bastar Olympics?

    • A regional multi-sport event launched by the Chhattisgarh government.
    • Conducted across all 7 districts of the Bastar region:
      • Bastar, Dantewada, Kanker, Kondagaon, Narayanpur, Sukma, Bijapur.
    • Includes 11 sports:
      Archery, Kabaddi, Athletics, Badminton, Football, Hockey, Karate, Weightlifting, Kho-Kho, Volleyball, Tug-of-war.
    Prelims-Relevant Themes Emerging

    • Internal Security: Platform for reducing alienation in LWE regions.
    • Social Issues: Women’s participation & empowerment.
    • Tribal Affairs: Inclusion of PVTGs, revival of cultural identity.
    • Governance: Last-mile delivery and state presence in remote areas.
    • Sports & Youth: Identification of rural sporting talent.
    Consider the following statements about Particularly Vulnerable Tribal Groups (PVTGs) in India: 

    1. PVTGs reside in 18 States and one Union Territory. 

    2. A stagnant or declining population is one of the criteria for determining PVTG status. 

    3. There are 95 PVTGs officially notified in the country so far. 

    4. Irular and Konda Reddi tribes are included in the list of PVTGs. 

    Which of the statements given above are correct? 

    (a) 1, 2 and 3 

    (b) 2, 3 and 4 

    (c) 1, 2 and 4 

    (d) 1, 3 and 4