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  • What are Bulk Drugs Parks?

    Himachal Pradesh is one of the states vying for the allotment of a bulk drug park under a central government scheme announced earlier this year for setting up three such parks across the country.

    Try this question:

    Q.The drug pricing system in India is an indirect outcome of the growing dependence on China for APIs. Discuss.

    What are Bulk Drugs or APIs?

    • A bulk drug also called an active pharmaceutical ingredient (API), is the key ingredient of a drug or medicine, which lends it the desired therapeutic effect or produces the intended pharmacological activity.
    • For example, paracetamol is a bulk drug, which acts against pain.
    • It is mixed with binding agents or solvents to prepare the finished pharmaceutical product, ie a paracetamol tablet, capsule or syrup, which is consumed by the patient.
    • APIs are prepared from multiple reactions involving chemicals and solvents.
    • The primary chemical or the basic raw material which undergoes reactions to form an API is called the key starting material, or KSM.
    • Chemical compounds formed during the intermediate stages during these reactions are called drug intermediates or DIs.

    Why is India promoting bulk drug parks?

    • India has one of the largest pharmaceutical industries in the world (third largest by volume) but this industry largely depends on other countries, particularly China, for importing APIs, DIs and KSMs.
    • This year, drug manufacturers in India suffered repeated setbacks due to disruption in imports.
    • Factories in China shut down when the country went into a lockdown, and later, international supply chains were affected as the Covid pandemic gripped the entire world.
    • The border conflict between India and China exacerbated the situation.

    What is the Centre’s scheme?

    • The Centre’s scheme will support three selected parks in the country by providing a one-time grant-in-aid for the creation of common infrastructure facilities.
    • The grant-in-aid will be 70 per cent of the cost of the common facilities but in the case of Himachal Pradesh and other hill states, it will be 90 per cent.
    • The Centre will provide a maximum of Rs 1,000 crore per park.
    • A state can only propose one site, which is not less than a thousand acres in area, or not less than 700 acres in the case of hill states.

    What does a bulk park offer?

    • A bulk drug park will have a designated contiguous area of land with common infrastructure facilities for the exclusive manufacture of APIs, DIs or KSMs, and also a common waste management system.
    • These parks are expected to bring down manufacturing costs of bulk drugs in the country and increase competitiveness in the domestic bulk drug industry.

    Why Himachal?

    • Himachal already has Asia’s largest pharma manufacturing hub, that is the Baddi-Barotiwala-Nalagarh industrial belt, and the state produces around half of India’s total drug formulations.
    • Himachal offers power and water at the lowest tariffs in the country, and the state also has an industrial gas pipeline.
    • It jumped nine places in this year’s ease-of-doing-business rankings declared by the Centre last month, securing the seventh position in the country.

  • Nyay Kaushal E-resource Centre

    CJI has inaugurated the first-ever e-resource centre and virtual court for traffic and transport to enable speedy justice for litigants, called ‘Nyay Kaushal’, at Nagpur.

    Must read edition:

    [Burning Issue] Judiciary in Times of COVID-19 Outbreak

    Nyay Kaushal Centre

    • It is a first of its kind e-resource centre in India that will facilitate electronic filing of cases in the Supreme Court, High Courts and district courts across the country.
    • It is meant to be a step at mitigating various inequalities, being connected to the Supreme Court, the High Courts and the Taluka Courts.
    • It will provide the easiest way of filing court matters by utilising technology. It will provide benefits in saving time, avoidance of exertion, travelling long distances, and a saving in costs.
    • The virtual court will be working from Katol in Nagpur district.

    It’s working

    • The virtual court can deal with all traffic challan cases from every corner of Maharashtra online.
    • It will be possible for the litigants to pay the fine and get the traffic challan case disposed of with the click of a button on a smartphone or a computer.

    Why need such a mechanism?

    • The biggest problem that came with the pandemic was that access to justice became conditional on access to technology.
    • This has ended up creating a divide between the ones who can afford technology and ones who cannot.
    • With the aid of virtual courts, our system of justice does not suffer and the rule of law continues to be maintained.

  • Street Vendors in India

    Recently PM distributed loans to nearly 300,000 street vendors under the PM SVANidhi scheme.

    Q. Discuss how Street-vending accounts for significant non-agricultural urban informal employment in India. Also, discuss how the PM SVANidhi scheme will help street vendors.

    SVANidhi scheme

    • The SVANidhi ensures a working capital loan up to Rs 10,000 for vendors and rewards digital transactions.
    • All street vendors who have been in the business on or before March 24, 2020, are eligible to avail the benefits.
    • For this scheme launched in the wake of the novel coronavirus pandemic, the Centre has earmarked a stimulus package of Rs 5,000 crore for nearly 50 lakh vendors.

    Street vendors in India

    • There are estimated 50-60 lakh street vendors in India, with the largest concentrations in the cities of Delhi, Mumbai, Kolkata, and Ahmedabad.
    • Most of them are migrants who typically work for 10–12 hours every day on average. Anyone who doesn’t have a permanent shop is considered a street vendor.
    • According to government estimates, street-vending accounts for 14 per cent of the total (non-agricultural) urban informal employment in the country.
    • The sector is riddled with problems. Licence caps are unrealistic in most cities — Mumbai, for example, has a ceiling of around 15,000 licences as against an estimated 2.5 lakh vendors.
    • This means most vendors hawk their goods illegally, which makes them vulnerable to exploitation and extortion by local police and municipal authorities.

     

    Identifying street vendors

    • The Street Vendors (Protection of Livelihood and Regulation of Street Vending) Act, 2014 was enacted to regulate street vendors in public areas and protect their rights.
    • The Act defines a “street vendor” as a person engaged in vending of articles… of everyday use or offering services to the general public, in…any public place or private area, from a temporary built-up structure or by moving from place to place”.
    • The Act envisages the formation of Town Vending Committees in various districts to ensure that all street vendors identified by the government are accommodated in the vending zones subject to norms.

  • What is the D614G mutation in coronavirus?

    While novel coronavirus is undergoing many mutations, one particular mutation called D614G, according to a study, has become the dominant variant in the global COVID-19 pandemic.

    Try this PYQ:

    Q.Which one of the following statements is not correct?

    (a) Hepatitis B virus is transmitted much like HIV.

    (b) Hepatitis B, unlike Hepatitis C, does not have a vaccine.

    (c) Globally, the number of people infected with Hepatitis B and C viruses is several times more than those infected with HIV.

    (d) Some of those infected with Hepatitis B and C viruses do not show the symptoms for many years.

    D614G mutation

    • When the virus enters an individual’s body, it aims at creating copies of itself. When it makes an error in this copying process, we get a mutation.
    • In this case, the virus replaced the aspartic acid (D) in the 614th position of the amino acid with glycine (G). Hence the mutation is called the D614G.
    • This mutated form of the virus was first identified in China and then in Europe. Later it spread to other countries like the U.S. and Canada and was eventually reported in India.

    Threats posed

    • This particular mutation aids the virus in attaching more efficiently with the ACE2 receptor in the human host, thereby making it more successful in entering a human body than its predecessors.
    • D614G show increased infectivity but it also displayed greater ability at attaching itself to the cell walls inside an individual’s nose and throat, increasing the viral load.

    How prevalent is it in India?

    • A study (reveals that the D614G was one of the most prevalent spike mutations even during the initial phase of the pandemic.
    • Since then, D614G mutation’s ‘relative abundance’ has increased over time to 70% and above, in most states except Delhi.

  • Asteroid 16 Psyche

    A recent study has found that asteroid 16 Psyche, which orbits between Mars and Jupiter, could be made entirely of metal and is worth an estimated $10,000 quadrillion.

    A NASA mission has recently landed on and collected samples from an asteroid. Do you remember that? Yes. Its the Asteroid Bennu

    16 Psyche

    • Located around 370 million km away from Earth, asteroid 16 Psyche is one of the most massive objects in the asteroid belt in our solar system.
    • The somewhat potato-shaped asteroid has a diameter of around 140 miles.
    • It was first discovered on March 17, 1853, by the Italian astronomer Annibale de Gasparis and was named after the ancient Greek goddess of the soul, Psyche.
    • Unlike most asteroids that are made up of rocks or ice, scientists believe that Psyche is a dense and largely metallic object thought to be the core of an earlier planet that failed in formation.
    • Its surface may mostly comprise iron and nickel, similar to the Earth’s core, according to a study.

  • [pib] Mansar Lake

    Mansar Lake Development Plan is getting fulfilled after a long wait of 70 years.

    Try this PYQ:

    Q.With reference to a conservation organization called Wetlands International, which of the following statements is/are correct?

    1. It is an intergovernmental organization formed by the countries which are signatories to Ramsar Convention.
    2. It works at the field level to develop and mobilize knowledge, and use the practical experience to advocate for better policies.

    Select the correct answer using the code given below:

    (a) 1 only

    (b) 2 only

    (c) Both 1 and 2

    (d) Neither 1 nor 2

    About Mansar Lake

    • Situated at about 37 km from Jammu, Mansar is a lake fringed by forest-covered hills, over a mile in length by half-a-mile in width.
    • Surinsar-Mansar Lakes are designated as Ramsar Convention in November 2005.
    • With all religions belief and heritage behind the Mansar Lake is also picking up its fame among the tourists with all its flora & fauna.
    • The lake has cemented path all around with required illumination, with projected view decks to enjoy flickering of seasonal birds, tortoise and fishes of different species.
    • There is a wildlife Sanctuary housing jungle life like Spotted Deer, Nilgai etc. besides other water birds such as Cranes, Ducks etc.

    Back2Basics: Ramsar Convention

    • The Convention on Wetlands of International Importance (better known as the Ramsar Convention) is an international agreement promoting the conservation and wise use of wetlands.
    • It is the only global treaty to focus on a single ecosystem.
    • The convention was adopted in the Iranian city of Ramsar in 1971 and came into force in 1975.
    • Traditionally viewed as a wasteland or breeding ground of disease, wetlands actually provide freshwater and food and serve as nature’s shock absorber.
    • Wetlands, critical for biodiversity, are disappearing rapidly, with recent estimates showing that 64% or more of the world’s wetlands have vanished since 1900.
    • Major changes in land use for agriculture and grazing, water diversion for dams and canals and infrastructure development are considered to be some of the main causes of loss and degradation of wetlands.

  • Need for Sponge cities Mission in India

    Issue of flood in the cities

    • Over 50 peple died in the wake of torrential rains in the third week of October in Hyderabad.
    • This experience is not unique to the city of Hyderabad, five years ago Chennai saw a massive flood costing much damage and lives.
    • Gurugram over the past few years comes to a complete standstill during the monsoon months.
    • And for Mumbai, the monsoon has become synonymous with flooding and enormous damages.

    Causes of frequent urban floods:

    Natural:

    • Meteorological Factors: Heavy rainfall, cyclonic storms and thunderstorms causes water to flow quickly through paved urban areas and impound in low lying areas.
    • Hydrological Factors: Overbank flow channel networks, occurrence of high tides impeding the drainage in coastal cities.
    • Climate Change: Climate change due to various anthropogenic events has led to extreme weather events.

    Anthropological:

    • Unplanned Urbanization: Unplanned Urbanization is the key cause of urban flooding. A major concern is blocking of natural drainage pathways through construction activity and encroachment on catchment areas, riverbeds and lakebeds.
    • Destruction of lakes: A major issue in India cities. Lakes can store the excess water and regulate the flow of water. However, pollution of natural urban water bodies and converting them for development purposes has increased risk of floods.
    • Unauthorised colonies and excess construction: Reduced infiltration due paving of surfaces which decreases ground absorption and increases the speed and amount of surface flow
    • Poor Solid Waste Management System: Improper waste management system and clogging of storm-water drains because of silting, accumulation of non-biodegradable wastes and construction debris.
    • Drainage System: Old and ill maintained drainage system is another factor making cities in India vulnerable to flooding.
    • Irresponsible steps: Lack of attention to natural hydrological system and lack of flood control measures.

    Impact of the devastation due to floods:

    • On economy: Damage to infrastructure, roads and settlements, industrial production, basic supplies, post disaster rehabilitation difficulties etc.
    • On human population and wildlife: Trauma, loss of life, injuries and disease outbreak, contamination of water etc.
    • On environment: Loss of habitat, tree and forest cover, biodiversity loss and large scale greenery recovery failure.
    • On transport and communication: Increased traffic congestion, disruption in rail services, disruption in communication- on telephone, internet cables causing massive public inconvenience.

    What is to be done

    1) Management of wetlands

    • We neglect the issues of incremental land use change, particularly of those commons which provide us with necessary ecological support — wetlands.
    •  We need to start paying attention to the management of our wetlands by involving local communities.
    • The risk is going to increase year after year with changing rainfall patterns and a problem of urban terrain which is incapable of absorbing, holding and discharging water.

    2) Implementing the idea of sponge cities

    • The idea of a sponge city is to make cities more permeable so as to hold and use the water which falls upon it.
    • Sponge cities absorb the rain water, which is then naturally filtered by the soil and allowed to reach urban aquifers.
    • This allows for the extraction of water from the ground through urban or peri-urban wells.
    • This water can be treated easily and used for city water supply.
    • In built form, this implies contiguous open green spaces, interconnected waterways, and channels and ponds across neighbourhoods that can naturally detain and filter water.
    • It implies support for urban ecosystems, bio-diversity and newer cultural and recreational opportunities,
    • These can all be delivered effectively through an urban mission along the lines of the Atal Mission for Rejuvenation and Urban Transformation (AMRUT), National Heritage City Development and Augmentation Yojana (HRIDAY) and Smart Cities Mission.

    On a top priority, such a mission should address the following.

    • 1) Wetland policy: In most of our lakes, the shallow ends, which often lie beyond the full tank level, have disappeared.
    • These shallow ends are best characterised as wetlands.
    • Regardless of ownership, land use on even this small scale needs to be regulated by development control.
    • 2) Watershed management and emergency drainage plan is next.
    • This should be clearly enunciated in policy and law.
    • 3) Ban against terrain alteration is third.
    • Lasting irreversible damage has been done to the city by builders, property owners, and public agencies by flattening terrain and altering drainage routes.
    • 4) Use of porus material: Our cities are becoming increasingly impervious to water, not just because of increasing built up but also because of the nature of materials used.
    • To improve the city’s capacity to absorb water, new porous materials and technologies must be encouraged or mandated across scales.
    • Examples of these technologies are bioswales and retention systems, permeable material for roads and pavement, drainage systems which allow storm water to trickle into the ground, green roofs and harvesting systems in buildings.

    Conclusion

    We can learn to live with nature, we can regulate human conduct through the state and we can strategically design where we build. We need to urgently rebuild our cities such that they have the sponginess to absorb and release water without causing so much misery and so much damage to the most vulnerable of our citizens, as we have seen.

  • What are Western Disturbances?

    With the approaching winter, minimum temperatures in the national capital have trended downward over the last due to the arrival of northwesterly winds called Western Disturbances.

    Try this PYQ:

    Q.Westerlies in the southern hemisphere is stronger and persistent than in northern hemisphere. Why?

    1. The southern hemisphere has less landmass as compared to the northern hemisphere.
    2. Coriolis force is higher in the southern hemisphere as compared to the northern hemisphere

    Which of the statements given above is/are correct?

    (a) Only 1

    (b) Only 2

    (c) Both 1 and 2

    (d) Neither 1 nor 2

    Western Disturbances

    • A western disturbance is an extratropical storm originating in the Mediterranean region that brings sudden winter rain to the northwestern parts of the Indian subcontinent.
    • It is a non-monsoonal precipitation pattern driven by the westerlies.
    • The moisture in these storms usually originates over the Mediterranean Sea, the Caspian Sea and the Black Sea.
    • Extratropical storms are global phenomena with moisture usually carried in the upper atmosphere, unlike their tropical counterparts where the moisture is carried in the lower atmosphere.
    • In the case of the Indian subcontinent, moisture is sometimes shed as rain when the storm system encounters the Himalayas.
    • Western disturbances are more frequent and strong in the winter season.

    Their significance

    • Western disturbances, specifically the ones in winter, bring moderate to heavy rain in low-lying areas and heavy snow to mountainous areas of the Indian Subcontinent.
    • They are the cause of most winter and pre-monsoon season rainfall across northwest India.
    • Precipitation during the winter season has great importance in agriculture, particularly for the rabi crops.
    • Wheat among them is one of the most important crops, which helps to meet India’s food security. An average of four to five western disturbances forms during the winter season.
    • The rainfall distribution and amount vary with every western disturbance.

    Also read: Polar Vortex 

  • Who is a Star Campaigner?

    The Election Commission (EC) has revoked the status of a veteran leader and former Madhya Pradesh CM as a star campaigner for the party.

    Try answering this question:

    Q.Ceiling on election expenses ends up being counterproductive and encourages candidates to under-report their expenditure. Critically analyse.

    Who is a Star Campaigner?

    • A star campaigner can be described as persons who are nominated by parties to campaign in a given set of constituencies.
    • These persons are, in almost all cases, prominent and popular faces within the party.
    • There is no specific definition according to law or the Election Commission of India.
    • Star campaigners for a party will not exceed 40 where it is a recognised political party.
    • For parties that are deemed unrecognized, the number of star campaigners will not be more than 20.

    Their purpose

    • Actors, celebrities and senior political party members are the ones who are nominated to be star campaigners.
    • This is based on the premise that a popular face, someone that the common voter can immediately identify and side with, can rake in more votes for that political party.

    How much does a star campaigner cost?

    • Section 77 (b) of The Representation of People’s Act, 1951 says that most of the expenses incurred by the campaigner “shall not be deemed to be an expenditure in connection with the election”.
    • In other words, all expenses will be borne by the respective political party.
    • For example, expenses borne by star campaigners on account of travel by air or by any other means of transport shall not be deemed as expenditure in connection with the election.
    • The manual to the Model Code of Conduct states that for the benefit of availing Section 77 (1) of The RP Act, a permit for the mode of transport for every star campaigner will be issued centrally and against their name.
    • It is also mandatory for this permit to be stuck on a prominent and visible place on the vehicle.

    A case for PMs

    • The MCC states that if the star campaigner is a PM or a former PM, then expenses incurred for bullet-proof vehicles required by centrally appointed security personnel will be borne by the government.
    • If another political dignitary accompanies this candidate, then 50 per cent of expenses incurred for security arrangements will be borne by the candidate.

  • Index of Eight Core Sector Industries

    The Office of Economic Advisor within the Department for Promotion of Industry and Internal Trade (DPIIT) has released the Index of Eight Core Industries (ICI) for September 2020.

    Try this PYQ:

    Q.In the ‘Index of Eight Core Industries’, which one of the following is given the highest weight?

    (a) Coal production

    (b) Electricity generation

    (c) Fertilizer production

    (d) Steel production

    What is the Index of Core Industries?

    • As the title suggests, this is an index of the eight most fundamental industrial sectors of the Indian economy and it maps the volume of production in these industries.
    • It gives the details of these eight sectors — namely Coal, Natural Gas, Crude Oil, Refinery Products (such as Petrol and Diesel), Fertilizers, Steel, Cement and Electricity.
    • Since these eight industries are the essential “basic” and/or “intermediate” ingredient in the functioning of the broader economy, mapping their health provides a fundamental understanding of the state of the economy.
    • In other words, if these eight industries are not growing fast enough, the rest of the economy is unlikely to either.

    ICI this year

    • This data is to focus on the trend of ICI growth over the past 6 months — that is, since the start of the Covid-19 pandemic and associated lockdowns.
    • A crucial factor in this regard would be the next wave of Covid-19 infections.
    • If there is a surge in the winter months — as is being witnessed in most Europe and the US — then India’s recovery will be dented yet again.