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Subject: Health

  • Orphan Diseases in India

    Central Idea

    • Health discussions often revolve around common ailments, such as diabetes, which affect a significant portion of the population.
    • However, amidst these well-known health issues, there are numerous rare/ orphan diseases that, though infrequent, can have devastating consequences for patients and their families.

    What are Orphan Diseases?

    • Rare diseases, often referred to as orphan diseases, are characterized by a low prevalence rate, typically affecting one person in a population of 10,000.

    Challenges Posed

    • Difficulty in Diagnosis: Rare diseases are challenging to diagnose, particularly for young medical practitioners who may have limited exposure to such cases. The rarity of these conditions means that many healthcare professionals may not have encountered them during their training.
    • Lack of Research: Limited prevalence has historically resulted in insufficient research efforts. With fewer cases to study, there has been a lack of scientific understanding and effective treatments for many rare diseases.
    • High Treatment Costs: While advances in medical research have led to the development of therapies for some rare diseases, the costs associated with these treatments are often exorbitant. From an Indian perspective, these costs can range from Rs. 1 million to Rs. 20 million per year, making them unaffordable for many.

    Initiatives and Progress in India

    • Increasing Awareness: Greater awareness of rare diseases and advancements in genomic technologies for diagnosis have begun to address these challenges. As awareness spreads, more cases are being identified and correctly diagnosed.
    • Regulatory Incentives: Several countries, including India, have introduced regulatory incentives to encourage pharmaceutical companies to invest in research and development for neglected diseases. This has led to increased interest in orphan drugs.
    • Patient-Driven Initiatives: Patient groups and organizations in India are actively contributing to rare disease research and treatment. One notable example is the Dystrophy Annihilation Research Trust (DART), which is conducting clinical trials for Duchenne’s muscular dystrophy.
    • Government Initiatives: The government’s National Policy for Treatment of Rare Diseases is gradually making an impact. It aims to address rare diseases prevalent in India, such as cystic fibrosis, hemophilia, lysosomal storage disorders, and sickle-cell anaemia.

    Lessons from Leprosy

    • Incidence Reduction: Leprosy, once prevalent in India, is now considered a rare disease due to successful efforts in reducing its incidence.
    • Research Benefits: Research on orphan diseases like leprosy can yield broader societal benefits. For instance, studies on synthetic antibiotics have shown a potential to curb the spread of leprosy to household relatives.
    • Government Goals: Research findings may contribute to achieving the government’s objective of making India leprosy-free by 2027.

    Conclusion

    • Rare diseases present unique healthcare challenges that have long been neglected.
    • However, recent progress in diagnosis, research, and patient-driven initiatives is gradually improving the landscape for rare disease patients in India.
    • As awareness grows and regulatory support continues, there is hope for enhanced diagnosis, treatment options, and affordability, ultimately improving the lives of those affected by these conditions.

  • Personalised Adaptive Learning (PAL) on DIKSHA Platform

    Central Idea

    • The National eGovernance Division (NeGD) plans to incorporate Personalised Adaptive Learning (PAL) into its existing Digital Infrastructure for Knowledge Sharing (DIKSHA) platform.
    • PAL offers individualized learning experiences based on students’ unique needs and abilities.

    DIKSHA 2.0 Portal

    • Diksha Portal was launched in 2017 to provide a digital platform to teachers giving them an opportunity to learn and train themselves and connect with the teacher community.
    • It serves as the National Digital Infrastructure for Teachers.
    • It aids teachers to learn and train themselves for which assessment resources will be available.
    • It houses digitized National Council of Educational Research and Training (NCERT) textbooks, teaching videos, and practice questions.
    • It also has assistive technologies for learners with disabilities, but it’s a static content repository.

    Integration of PAL

    • NCERT seeks MeitY’s expertise in implementing PAL within DIKSHA.
    • PAL provides customized learning paths for each student based on their learning progress.
    • PAL can loop back students to basic concepts if they make mistakes, enhancing learning efficiency.

    Challenges and Implementations in States

    • PAL development involves categorizing and tagging content, potentially creating new material.
    • Chemistry, Mathematics, and Physics for Classes 9 to 12 are prioritized for PAL development.
    • Several states like Andhra Pradesh, Assam, and Haryana experimented with PAL, facing budget constraints.

  • Vital link between Soil Micronutrients and Human Health

    Micronutrients

    Central Idea

    • A new study has underscored the significant connection between soil micronutrients and human nutritional outcomes, particularly among children and adult women.
    • The research, titled “Soil Micronutrients Linked to Human Health in India,” emphasizes that soil deficiency in key nutrients contributes to nutritional deficiencies in vulnerable populations.

    What are Soil Micronutrients?

    • Micronutrients are essential elements required by plants in smaller quantities compared to macronutrients (nitrogen, phosphorus, and potassium).
    • These micronutrients play crucial roles in various physiological and biochemical processes within plants.

    Types of Micronutrients

    Role in Plants Deficiency Symptoms
    Iron (Fe) Chlorophyll synthesis, photosynthesis Chlorosis (yellowing) of leaves
    Manganese (Mn) Photosynthesis, enzyme activation Interveinal Chlorosis, poor fruit dev.
    Zinc (Zn) Enzyme activity, protein synthesis Stunted growth, small leaves
    Copper (Cu) Enzyme activity, chlorophyll formation Leaf wilting, reduced growth
    Molybdenum (Mo) Nitrogen fixation, enzyme activity Poor growth, yellowing of leaves
    Boron (B) Cell wall formation, auxin synthesis Distorted growth, reduced fruit dev.
    Chlorine (Cl) Osmotic balance, photosynthesis Osmotic imbalance, leaf damage
    Nickel (Ni) Enzyme cofactor Specific deficiency symptoms

     

    Soil Micronutrients and Health Correlation

    • Soil-Zinc Relationship: The study indicates that districts with higher soil zinc content exhibit lower rates of child stunting and underweight, signifying the importance of soil zinc in nutritional outcomes.
    • Height and Soil Zinc: Soil zinc availability corresponds to an increase in the height of women, suggesting a relationship between micronutrient-rich soil and human growth.
    • Soil Iron and Anemia: The study highlights a strong connection between soil iron availability and anemia among women, as well as haemoglobin levels in both children and women.

    Implications for India

    • Soil Nutrient Deficiency: The study holds significance for India, where over 35% of soil is deficient in zinc and around 11% is deficient in iron.
    • Micronutrient Deficiency: India faces significant micronutrient deficiency issues, with roughly one-third of the global population experiencing these deficiencies. Iron deficiency is a leading cause of anemia in the country.

    Addressing Malnutrition and Stunting

    • Malnutrition and Stunting: With a child stunting rate of approximately 39%, malnutrition is a leading risk factor for disability-adjusted life years (DALYs) loss, as per the Lancet’s Global Burden of Disease Study.
    • Study Insights: The researchers’ study reveals that a one standard deviation increase in satisfactory soil zinc is associated with a reduction in stunting and underweight among children.

    Implications for Policy

    • Mitigating Anaemia: The study suggests that soil mineral availability could serve as a valuable tool for mitigating the widespread prevalence of anaemia in the population.
    • Wealthier Households: The link between soil zinc availability and childhood stunting is particularly notable in wealthier households, potentially due to additional health constraints that poorer households face.

    Way forward

    • Soil Enrichment and Agricultural Practices: Implement soil enrichment strategies to address micronutrient deficiencies. Promote sustainable farming practices to enhance soil health and nutrient content.
    • Nutrient-Fortified Crops: Invest in research for nutrient-fortified crops rich in essential micronutrients. Encourage the cultivation and consumption of these crops to boost dietary intake.
    • Nutritional Education: Launch awareness campaigns about balanced nutrition and micronutrient importance. Educate communities on the role of micronutrients in maintaining good health.
    • Women’s Health Programs: Establish tailored health programs for women during pregnancy and lactation. Ensure access to supplements like iron to combat anaemia.

    Conclusion

    • The study’s findings reaffirm the crucial link between soil micronutrients and human health outcomes, particularly in the context of child stunting, underweight, and anaemia.
    • With India grappling with both soil nutrient deficiency and widespread micronutrient deficiencies among its population, this research provides insights that could inform targeted policy interventions.

  • Patient Safety and Neonatal Care: India’s Efforts and Challenges

    Central Idea

    • The recent conviction of a former British nurse highlights the importance of patient safety in healthcare systems.
    • While neonatal safety is not governed by exclusive rules, there are provisions to ensure the wellbeing of newborns and minimize potential risks.

    Patient Safety Provisions in India

    • Defining Patient Safety: Patient safety is defined as freedom from harm or potential harm associated with healthcare provision, according to the ‘National Patient Safety Implementation Framework (2018-2025).’
    • Legal Protection: Patients in India are protected under various laws, including the Consumer Protection Act, Clinical Establishment Act, and mechanisms by the National Pharmaceutical Pricing Authority and Drugs Controller General of India to safeguard patients’ rights.
    • Fragmented Laws: Patient safety is governed by a range of laws, from the Hippocratic Oath to clinical establishment regulations, reflecting a multifaceted approach to ensure safe healthcare practices.

    Neonatal Safety and Care

    • Proactive Measures: While no exclusive rules exist for neonatal care, provisions against issues like mix-ups and abductions are present. Deliberate harm is extremely rare and often linked to complex psychiatric illnesses.
    • Comprehensive Provisions: Neonatal safety is ensured through comprehensive provisions that include staffing, equipment, infection control, parental involvement, training, and continuing medical education.
    • Human Errors: In a country with a high birth rate, human errors may occur in neonatal care, but planned, deliberate harm remains an exceptional occurrence.

    Neonatal Health Challenges

    • Global Neonatal Deaths: Despite a decline in global neonatal deaths, newborns face the highest risk of death within the first 28 days of life. A significant proportion of under-five deaths occur during the newborn period.
    • India’s Scenario: India’s infant mortality rate is gradually declining, but pre-term birth, complications during birth, infections, and birth defects remain major causes of neonatal deaths.
    • Improving Neonatal Survival: Ensuring proper neonatal care and addressing the key challenges can contribute to reducing neonatal mortality rates and improving child health outcomes.

    Promoting Neonatal Safety

    • Midwife-Led Continuity of Care: Professional midwives providing midwife-led continuity of care (MLCC) significantly reduce the risk of neonatal and pre-term birth. This approach emphasizes the importance of skilled care during childbirth and the immediate postnatal period.
    • Seeking Prompt Medical Care: Families are advised to seek prompt medical care in case of danger signs in newborns and to follow vaccination schedules for timely protection. This proactive approach helps prevent and manage potential health risks in neonates.
    • Ensuring Proper Training: Proper training of healthcare providers, especially those in neonatal services, is crucial for maintaining high-quality care and adherence to safety standards.

    Conclusion

    • Patient safety and neonatal care form the foundation of a robust healthcare system.
    • The challenges of neonatal care require ongoing attention, collaboration, and innovation to ensure the best outcomes for the youngest members of society.

  • Jan Vishwas Bill

    Central Idea

    • The Jan Vishwas Bill, aimed at enhancing ease of doing business, has sparked a heated debate over certain amendments that modify the Drugs and Cosmetics Act, 1940.
    • While the bill intends to streamline regulatory provisions, critics argue that it may allow manufacturers of substandard medicines to evade imprisonment and instead pay fines for their offenses.

    Jan Vishwas Bill

    • Amendment I: The first amendment under the Jan Vishwas Bill eliminates imprisonment for companies repeatedly using government analysis or test reports to promote their products. Instead, offenders will be subject to a fine not less than five lakh rupees, as opposed to the previous fine of not less than ten thousand rupees.
    • Amendment II: The second, more contentious amendment allows for the “compounding” of offenses under section 27 (d) of the existing Drugs and Cosmetics Act. Compounding enables companies to pay a fine as an alternative to undergoing criminal proceedings. However, section 27 (d) covers offenses related to drugs not of standard quality (NSQ) or colloquially termed substandard drugs.

    Controversy and Concerns

    • NSQ Drugs and Their Risks: Substandard drugs (NSQ) are products that fail to meet Indian Pharmacopoeia requirements, leading to potential harm to consumers. Examples include drugs with low levels of active ingredients, affecting treatment effectiveness and causing antibiotic resistance.
    • Criticism of Inclusion of Section 27 (d): The inclusion of NSQ drugs under section 27 (d) for compounding has raised concerns among many. Critics argue that it could allow companies to escape liability for manufacturing substandard products by merely paying a fine.

    Scope of Offenses Eligible for Compounding

    • Eligible Offenses: Compounding will be available for manufacturers whose drugs are NSQ, enabling them to avoid criminal proceedings by paying a fine.
    • Government’s Stance: The government contends that compounding will be reserved for minor aberrations or quality control issues, and companies involved in spurious or adulterated drug manufacturing will not be eligible. It aims to offer an alternate mechanism for minor offenses to reduce litigation delays and foster ease of doing business.

    Impact on Good Manufacturing Practices

    • Schedule M Requirements: In 2018, amendments were made to Schedule M of the drug act to improve drug manufacturing practices. However, a significant number of drug manufacturers have yet to adopt these measures.
    • Compounding for Non-Compliance: Under the Jan Vishwas Bill, companies failing to implement Schedule M requirements within the stipulated time will be prosecuted under section 27 (d).

    Industry Perspective

    • Industry Support for Compounding: Some manufacturers view compounding as a positive step, preventing minor offenses from leading to lengthy litigation and business disruptions. They argue that non-intentional aberrations should not result in imprisonment, especially for first-time offenders.
    • Balancing Enforcement and Business Growth: Advocates of compounding emphasize that strict action should be taken against repeat offenders or those engaging in offenses with malicious intent. Balancing enforcement and encouraging quality production will enable the pharmaceutical industry to thrive and produce safe, effective products.

    Conclusion

    • Striking a balance between enabling business growth and enforcing quality standards will be critical in determining the long-term impact of the bill on the pharmaceutical industry.

    Also read:

    In news: Jan Vishwas Bill, 2022

  • WHO Report on Tobacco Control

    Central Idea

    • The WHO has released a report on the progress made in global tobacco control in the last 15 years.
    • The report highlights the impact of the MPOWER measures, introduced by WHO, to combat tobacco use and protect public health.

    What are MPOWER measures by WHO?

    • The World Health Organization (WHO) has introduced a set of global health targets known as “MPOWER measures” to address the global tobacco epidemic.
    • These measures are evidence-based strategies aimed at reducing tobacco use and its associated health risks.
    • The MPOWER measures were developed to assist countries in implementing effective tobacco control policies and interventions.
    • The term “MPOWER” is an acronym, with each letter representing a specific area of focus:
    1. M – Monitor tobacco use and prevention policies
    2. P – Protect people from tobacco smoke
    3. O– Offer help to quit tobacco use
    4. W – Warn about the dangers of tobacco
    5. E – Enforce bans on tobacco advertising, promotion, and sponsorship
    6. R – Raise taxes on tobacco products

    Key Findings of the Report

    • Reduction in Smoking: Globally, there are 300 million fewer smokers today, with smoking prevalence declining from 22.8% in 2007 to 17% in 2021. In a city-specific example, hundreds of enforcement drives and awareness campaigns resulted in a 27% reduction in smoking in public places.
    • Impact of MPOWER Measures: The MPOWER measures have positively impacted tobacco control efforts worldwide. 71% of the global population, or 5.6 billion people, are protected by at least one MPOWER measure, up from 5% in 2008. The number of countries implementing at least one measure has increased from 44 to 151.
    • Global Challenges: Despite progress, 44 countries still do not implement any MPOWER measure, and there are shortcomings in enforcing smoke-free policies in healthcare facilities and restaurants.
    • Focus on Second-Hand Smoke: The report emphasizes the importance of curbing second-hand smoke, which causes significant health risks, including 1.3 million tobacco-related deaths among non-smokers annually. India is among the countries making efforts to control this aspect.

    India’s Achievements and Areas for Improvement

    • Health Warning Labels: India ranks among the top 10 countries for having health warning labels on cigarette packs, with 85% of packs carrying warnings on both sides.
    • Ban on E-cigarettes: India has implemented a ban on the sale of e-cigarettes, which WHO recognizes as an essential step in curbing the tobacco epidemic.
    • Smoking Bans: India has banned smoking in healthcare facilities and educational institutions, although there is scope for improvement in terms of enforcement.
    • Warnings on OTT Platforms: India is taking significant steps to implement warnings on over-the-top (OTT) platform content showing tobacco use, making it the first country to do so. This move is crucial, given the increased subscriptions to OTT platforms during the pandemic.

    Expert Perspectives

    • Experts suggest the need for further amendments to India’s comprehensive tobacco control laws, with specific attention to banning the loose sale of cigarettes.
    • Implementing warnings on OTT platforms is seen as a necessary measure to reach a broader audience, especially young viewers.

    Conclusion

    • The WHO report highlights the global progress in reducing smoking prevalence and implementing tobacco control measures.
    • While India has made significant strides in certain aspects of tobacco control, there are areas that require continued attention and action.

  • Is there a Rural Bias in National Surveys?

    survey

    Central Idea

    • The Centre has appointed a panel to review the methodology of the National Statistical Organisation (NSO).
    • This step comes amid discussions regarding the accuracy of national surveys such as the National Sample Survey (NSS), National Family Health Survey (NFHS), and Periodic Labour Force Survey (PLFS).

    About National Statistical Office (NSO)

    Historical Background:

    • The NSO was established in 1950 as the Central Statistical Office (CSO) under the Ministry of Planning.
    • It was later renamed the National Sample Survey Office (NSSO) in 1970 and subsequently became the NSO in 2019.
    • Over the years, it has evolved to become the primary statistical agency in India.

    Organizational Structure:

    • The NSO consists of several divisions and units responsible for different statistical functions.
    • These include the Survey Design and Research Division, Field Operations Division, Data Processing Division, National Accounts Division, Price Statistics Division, and Social Statistics Division, among others.

    Key organizations under NSO: Central Statistical Office (CSO)

    • The CSO is a part of the NSO and focuses on macroeconomic statistics and national income accounting.
    • It is responsible for producing key economic indicators such as the Gross Domestic Product (GDP), Index of Industrial Production (IIP), Consumer Price Index (CPI), and Wholesale Price Index (WPI).

    Important Surveys Conducted:

    1. Population Census: The NSO conducts a decennial Population Census in collaboration with the Registrar General and Census Commissioner of India. The census collects data on population size, composition, and other demographic characteristics.
    2. National Sample Survey (NSS): The NSS is a large-scale household survey conducted by the NSO to collect data on various socio-economic aspects. It provides valuable information on employment, consumer expenditure, poverty, education, health, and other important indicators.
    3. Economic Census: The NSO conducts the Economic Census periodically to collect data on the number of business establishments, their distribution across sectors and regions, employment, and other relevant economic variables.
    4. Annual Survey of Industries (ASI): The ASI is conducted by the NSO to collect data on the performance and structure of the industrial sector in India. It covers various aspects such as employment, wages, production, and financial indicators.
    5. Agricultural Census: The NSO conducts the Agricultural Census periodically to collect comprehensive data on agricultural holdings, cropping patterns, land use, irrigation, livestock, and other relevant agricultural variables.
    6. Health and Morbidity Survey: The NSO conducts surveys on health and morbidity to gather data on healthcare utilization, access to healthcare services, prevalence of diseases, and other health-related indicators.

    Why under review?

    • Concerns about Methodology: Experts argue that the usage of outdated survey methodology in national surveys may have systematically underestimated India’s development.
    • Narrower capture of data: The dynamic nature of the Indian economy over the last 30 years might not be adequately captured.
    • Different Perspectives: While some experts believe there is no systematic underestimation of development by these surveys, they acknowledge the presence of errors that should be minimized.
    • Role of National Data: Accurate national-level data is crucial for research, policymaking, and development planning.

    Focus on NFHS Data

    • Crucial development data: The National Family Health Survey provides vital data on health and family welfare indicators.
    • Claims of Bias: Some experts suggest that national surveys, including NFHS, may exhibit a “rural bias” in representation, leading to an underestimation of India’s development.
    • Issue of Error and Random Bias: While errors in population estimations have occurred in some rounds, they appear to be random rather than systematic.

    Minimizing Errors in Data Collection

    • Improving Response Rates: Efforts to increase response rates in both rural and urban areas can lead to more accurate data.
    • Importance of Sample Weights: Proper assignment of sample weights can significantly improve the accuracy of estimations and correct any underrepresentation of rural or urban populations.

    Recommendations for the Review Panel:

    • Addressing Concerns: The review panel should focus on ensuring that the samples are adequately representative rather than proposing a complete overhaul of survey methodologies.
    • Correcting Bias Where It Exists: While addressing any perceived biases, the panel should aim to eliminate bias where it genuinely exists without introducing new biases in policymaking and planning.

    Conclusion

    • Accurate data serves as the bedrock of progress and development in the country.
    • Reviewing the methodology of national surveys is vital to ensure accurate and representative data for India’s development.
    • Striking the right balance between addressing concerns and minimizing errors will lead to more informed decision-making and policy formulation.

  • Tele-MANAS counsels 2 Lakh distressed people

    manas

    Central Idea: The government-run national tele-mental health programme, Tele MANAS, has achieved a significant milestone by receiving over 2,00,000 calls from individuals across India since its launch in October 2022.

    What is Tele-MANAS?

    • Tele Mental Health Assistance and Networking across States (Tele-MANAS) initiative has been launched by the Ministry of Health & Family Welfare in October 2022.
    • It aims to provide free tele-mental health services all over the country round the clock, particularly catering to people in remote or under-served areas.

    Implementation of the scheme

    • Counselling: The programme includes a network of 38 tele-mental health centres of excellence spread across 27 States and UTs working in over 20 languages.
    • Helpline: A toll-free, 24/7 helpline number (14416) has been set up across the country allowing callers to select the language of choice for availing services. Service is also accessible at 1-800-91-4416.

    Two-tier working

    • Tele-MANAS will be organised in a two-tier system; Tier 1 comprises state Tele-MANAS cells which include trained counsellors and mental health specialists.
    • Tier 2 will comprise specialists at District Mental Health Programme (DMHP)/Medical College resources for physical consultation and/or e-Sanjeevani for audio-visual consultation.

    Call Demographics and Concerns

    • Age Group: Two-thirds of the callers fall in the 18-45 years age group, while 12.5% belong to the 46-64 years age group, and 8% are below 18 years of age.
    • Gender Distribution: Of the two lakh calls, 59.6% were made by male callers, and 40% by female callers.
    • Top Concerns: The most common reasons for seeking help were general feelings of sadness (28.8%), sleep-related problems (27.6%), anxiety (20.4%), relationship issues (10%), aggression (9.2%), and low interest in activities (9.7%).

    Expansion of the scheme

    • The initial rollout providing basic support and counselling through a centralized Interactive Voice Response system (IVRS) is being customized for use across all States and UTs.
    • It is being linked with other services like National teleconsultation, e-Sanjeevani, Ayushman Bharat, mental health professionals, health centres, and emergency psychiatric facilities for specialized care.
    • This will not only help in providing immediate mental healthcare services but also facilitate a continuum of care.
    • Eventually, this will include the entire spectrum of mental wellness and illness, and integrate all systems that provide mental health care.

    Back2Basics: National Tele Mental Health Programme (NTMHP)

    • The Indian Government announced the National Tele Mental Health Programme (NTMHP) in the Union Budget 2022-23.
    • The National Institute of Mental Health and Neurosciences (NIMHANS) in Bengaluru is the nodal centre for the programme.
    • The programme sought to establish a digital mental health network that can address the mental health crisis in the wake of the COVID-19 pandemic.
    • The pandemic has brought forth challenges to mental health, and the NTMHP aims to provide accessible and affordable mental health services to all.
    • The programme will involve the use of digital platforms such as teleconsultations, chatbots, and mobile applications to deliver mental health services.
    • The NTMHP will integrate with existing mental health services to provide a comprehensive and coordinated approach to mental healthcare.

  • India achieves record DPT3 vaccination coverage in 2022: WHO

    dpt3

    Central Idea

    • The coverage rate for DPT3 vaccines (diphtheria, pertussis, and tetanus) in India reached an all-time high of 93% in 2022, surpassing the pre-pandemic record of 91% in 2019.
    • This significant increase from the 85% coverage in 2021 was reported by the World Health Organization (WHO).

    What is DPT3?

    • DPT3 vaccines refer to a combination vaccine that provides protection against three infectious diseases: diphtheria, pertussis (whooping cough), and tetanus.
    • The “DPT” in DPT3 stands for the initials of these three diseases:
    1. Diphtheria: It is a bacterial infection that primarily affects the respiratory system. It can cause severe throat and nose congestion, difficulty breathing, and in severe cases, it can lead to heart and nerve damage.
    2. Pertussis (Whooping Cough): It is a highly contagious respiratory infection caused by the bacterium Bordetella pertussis. It is characterized by severe coughing fits, often accompanied by a “whooping” sound when gasping for breath. Pertussis can be particularly dangerous for infants and young children.
    3. Tetanus: Also known as lockjaw, is a bacterial infection caused by the bacterium Clostridium tetani. It enters the body through wounds or cuts and produces a toxin that affects the nervous system, leading to muscle stiffness and spasms, particularly in the jaw and neck muscles.

    WHO records on immunization

    • DPT3 Coverage Recovery: The WHO South-East Asia Region saw the DPT3 coverage recover to pre-pandemic levels of 91% in 2022, a significant increase from 82% in 2021.
    • Measles Vaccine Coverage: The region also witnessed a six percent improvement in measles vaccine coverage, rising to 92% in 2022 from 86% in 2021.
    • Zero-Dose Children: The number of zero-dose children (those who have not received even the first dose of the DPT vaccine) halved from 4.6 million in 2021 to 2.3 million in 2022.
    • Partially Vaccinated Children: The number of partially vaccinated children (those who received at least one dose but not the complete three-dose series) decreased from 1.3 million in 2021 to 650,000 in 2022.

  • Poverty’s Impact on Brain Development

    poverty brain

    Introduction

    • In 1844, Frederich Engels observed that poor living conditions had physical effects on the poor, manifesting in various health issues.
    • Neuroscientists in the 1960s discovered that growing up in poverty could hinder brain development in rats.
    • Recent studies have shown a correlation between low-income families and lower cortical volume, poor academic performance, and smaller hippocampus in human children.

    The Link between Poverty and Brain Development

    • Poverty’s Effect on the Brain: Poverty has been found to affect brain development in children and young adults.
    • Cortex and Academic Performance: Studies in 2015 revealed that children from low-income families had lower cortical volume and performed poorly in academic tests.
    • Importance of the Hippocampus: Another study in 2015 highlighted the correlation between family socioeconomic status and the volume of the hippocampus, a key region for learning and memory.

    New Study on Anti-Poverty Policies and Hippocampus Size

    • The Study: Researchers from Harvard University and Washington University conducted a study published in May 2023 in the journal Nature Communication.
    • Data: The study analyzed brain scans of over 10,000 children aged 9-11 from 17 U.S. states with varying costs of living and anti-poverty programs.
    • Findings: Children from low-income families had a smaller hippocampus, but generous anti-poverty policies significantly reduced this risk.
    • State-Level Public Policies: The study highlights the potential of state-level public policies to address the correlation between brain development and low income.

    Implications for Children’s Health and Well-being

    • Psychological Impact: Impaired hippocampal development is associated with a higher risk of mental health issues such as major depressive disorder and post-traumatic stress disorder.
    • Internalizing and Externalizing Psychopathologies: The study found a negative association between family income and the incidence of internalizing and externalizing psychopathologies in children.
    • Impact of Anti-Poverty Policies: Generous cash benefits were associated with larger hippocampal volumes and reduced internalizing problems in low-income households.

    Considerations and Limitations

    • Systemic Discrimination: Poverty is often a result of systematic discrimination, such as racial disparities.
    • Alternative Explanations: The study aimed to rule out alternative explanations, including racial and ethnic factors, but acknowledges the need for further investigation.
    • Applicability to Other Contexts: The study’s findings may not directly apply to other countries like India, given different macroeconomic conditions.

    Role of Welfare and Policy

    • Financial Resources and Stressors: Access to more financial resources can help shield families from chronic stressors associated with low income, potentially influencing hippocampal development.
    • Generous Anti-Poverty Policies: Such policies not only increase family income but also enable families to make decisions that reduce stress, such as working fewer hours.
    • Investing in Social Safety Net Programs: Investments in social safety net programs can mitigate socioeconomic disparities in neurodevelopment, addressing mental health, education, and economic challenges.

    Conclusion

    • Longitudinal Study: The researchers will continue studying the mental health and brain development trajectories of the study’s participants to examine the influence of policy changes.
    • Importance of Social Safety Net Programs: The study underscores the significance of investing in social safety net programs to address the consequences of socioeconomic disparities in brain development.