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  • Health Sector – UHC, National Health Policy, Family Planning, Health Insurance, etc.

    On Digital Health ID, proceed with caution

    Much recently, the Prime Minister had launched the Digital Health ID project (DHID), generating debate on issues related to the use of technology in a broken health system.

    Explained: Digital Health ID

    Good intents of the DHID

    • The key objective of DHID is to improve the quality, access and affordability of health services by making the service delivery “quicker, less expensive and more robust”.
    • The ambition is undoubtedly high. Given that health systems are highly complex, the DHID would hardly be able to address some of the issues plaguing it.

    Why need DHID?

    (a) Record maintenance

    • The use of technology for record maintenance is not just inevitable but necessary. Its time has certainly come.
    • A decade ago, the process to shift towards electronic medical records was initiated in the private sector.
    • It met with limited success, despite the strong positives.
    • With DHID, the burden of storing and carrying health records for every visit to the doctor is minimised.

    (b) Better tracking of medical history

    • The doctor has instant access to the patient’s case history –the treatment undertaken, where and with what outcomes — enabling more accurate diagnosis and treatment.
    • As the DHID enables portability across geography and healthcare providers, it also helps reduce re-testing or repeating problems every time a patient consults a new doctor.
    • That’s a huge gain, impacting the quality of care and enhancing patient satisfaction and confidence.

    (c) Better Diagnosis

    • DHID can have a transformative impact in promoting ecosystems that function as paperless facilities.
    • Paperless hospitals can promote early diagnosis before the patient reaches the doctor after spending long hours in queue.
    • The doctor can already go through the patient’s record and the pharmacist can make the drugs available by the time the patient reached its counter.

    (d) Promoting medical research

    • Digitisation of medical records is another important positive, given the problems related to space and retrieving huge databases.
    • Well organised repositories that enable easy access to records can stimulate much-needed research on medical devices and drugs.
    • This storehouse of patient data can be valuable for clinical and operational research.

    Given our population, would this be an idealistic expectation?

    • We need to conduct pilot studies to assess the use of technology for streamlining patient flows and medical records and thereby increase efficiencies across different typologies of hospitals and facilities.
    • While technology helps smoothen processes and enhance patient experience, there is a cost attached.
    • Investments have to be made upfront and results should not be expected overnight.

    Issues with DHID

    (a) A costly affair

    • In the immediate short run, DHID will increase administrative costs by about 20 per cent, due to the capital investment in data infrastructure.
    • Over the long run, the additional cost to healthcare is expected to be about 2 per cent.
    • Any scaling up of this reform would require extensive fiscal subsidies and more importantly providing techno-logistical support to both government and private hospitals.

    (b) Privacy concerns

    • Most important is the issue of privacy, the high possibility of hacking and breach of confidentiality.
    • The possibility of privacy being violated increases with the centralisation of all information.
    • Though it is said that the patient is the owner of the information, how many of us deny access, as a matter of routine, when we download apps or programmes that seek access to all our records?
    • How far is this “consent” practical for an illiterate, vulnerable patient desperate to get well?
    • So, taking refuge behind a technical statement that access is contingent on patient consent is unconvincing.

    Ground situation in India

    • Inherently unaffordable healthcare: The costs in the Indian context can be high and that should lead to a careful assessment of the project.
    • Digital divide: Such a scenario is not inconceivable and in the case of health, may cause immense hardship to the most marginalised sections of our population.
    • Infrastructure gap: A large majority of facilities do not have the required physical infrastructure — electricity, accommodation, trained personnel.
    • Usual nature of technical glitches: Cards getting corrupted, servers being down, computers crashing or hanging, and power outages are common in India.
    • Conformity over data synchronization: The inability to synchronise biometric data with ID cards has resulted in large-scale exclusions of the poor from welfare projects.
    • Accuracy of records: Besides, the efficacy of the DHID hinges on the assumption that every visit and every drug consumed by the patient is faithfully and accurately recorded.
    • Increased workload on Medical Professionals: Moreover, while electronic mapping of providers may enable patients to spot a less busy doctor near their location, it is simplistic to assume that the patient will go there.

    Plugging the existing gaps

    • Patient preference for a doctor is dependent upon perception and trust. Likewise, teleconsultations need a huge backend infrastructure and organisation.
    • Teleconsulting has certainly helped patients access medical advice for managing minor ailments, getting prescriptions on the phone and even getting drugs delivered home.
    • But in handling chronic diseases that necessitate continuity of care, teleconsultations have been problematic and cannot be substituted for actual physical examination.
    • Continuity of care is central to good outcomes in inpatient management of chronic diseases.
    • The one serious shortcoming of using teleconsultation for such management is the high attrition rate of doctors within the context of an overall shortage of doctors.
    • Technology can be of little use in the absence of doctors and basic infrastructure.

    Way forward

    • What is needed is building very robust firewalls and trust.
    • Seeing the frequency with which Aadhaar cards have been breached, it is not unreasonable to be concerned with this issue and the implications it has at the family and societal levels.
    • For this reason, instead of a big bang approach, it is better to go slow and steady.
    • That’s the only way to ensure that a good policy does not die along the way due to poor implementation.

     

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  • Nobel and other Prizes

    First Nobel for Climate Science

    Three scientists received the Nobel Prize in Physics for work that is essential to understanding how the Earth’s climate is changing, pinpointing the effect of human behaviour on those changes and ultimately predicting the impact of global warming.

    Who are the laureates?

    • The winners were Syukuro Manabe, Klaus Hasselmann of Germany, and Giorgio Parisi from Italy.
    • In 2015, at a UK-based climate-focused online publication sought to identify the three most influential climate change research papers ever published.
    • The paper that received the most votes was one by Syukuro Manabe and Richard Wetherald way back in 1967.
    • These reports for the first time, had described the impact of carbon dioxide and water vapour on global warming.

    Citation for their Climate Model

    • Manabe is a senior meteorologist and climatologist at Princeton University.
    • In the 1960s, he led ground-breaking research into how increased levels of carbon dioxide lead to higher temperatures on the surface of the Earth.
    • This laid the foundation for the development of current climate models.
    • Hasselmann is a German physicist and oceanographer who greatly advanced public understanding of climate change through the creation of a model that links climate and chaotic weather systems.
    • Parisi has focused on quantum field theory and complex systems.

    Why it is significant feat?

    • This is the first-time climate scientists have been awarded the Physics Nobel.
    • The IPCC had won the Peace Nobel in 2007, an acknowledgement of its efforts in creating awareness for the fight against climate change.
    • A Chemistry Nobel was also awarded to Paul Crutzen in 1995, for his work on the ozone layer, is considered the only other time someone from atmospheric sciences has won this honour.
    • The recognition of Manabe and Hasselmann, therefore, is being seen as an acknowledgement of the importance that climate science holds in today’s world.

     

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  • Road and Highway Safety – National Road Safety Policy, Good Samaritans, etc.

    [pib] National Road Safety Board

    The Ministry of Road Transport & Highways has notified the constitution of the National Road Safety Board.

    National Road Safety Board

    • The NRSB will be constituted of a panel of seven members and a chairman, with the members having experience in the fields related to road safety, traffic regulation, urban planning, civil engineering and police enforcement and investigation.
    • Additionally, the board will also comprise of technical committees to look into a variety of aspects of road safety from civil engineering to vehicle construction and safety equipment.

    Why need such board?

    • Along with the rapid expansion and up-gradation on the road network and the enforcement of higher safety standards for vehicles, the Government is now actively looking into the safety of roads too.

    Terms of reference

    • The Head Office of the Board shall be in the National Capital Region and the Board may establish offices at other places in India.
    • The Board shall be responsible for promoting road safety, innovation and adoption of new technology and for regulating traffic and motor vehicles.

    For this purposes, inter alia, the Board shall formulate

    • specific standards for road safety, traffic management and road construction for hilly regions
    • guidelines for capacity building and development of skills for traffic police, hospital authorities, highway authorities, educational and research organizations and other organizations
    • guidelines for establishing and operating trauma facilities and para-medical facilities, for consideration by the Central Government
    • provide technical advice and assistance to the Central Government, State Governments and local authorities on road safety and traffic management

    Key provision: Protection of Samaritans

    • The board aims to promote Good Samaritans and good practices in road safety and traffic management
    • Good Samaritans who rescue victims of serious road accidents and rush them to a hospital within the golden hour will now be rewarded with ₹5,000.
    • They will also be eligible for a cash prize of ₹1 lakh which will be given to 10 such Samaritans in a year.
    • It has been felt that there is a need to motivate the general public through cash awards and certificates to help the road accident victims in emergency situation and to boost their morale.
    • The categories of accidents that will make one eligible for the award will include those that result in a major surgery or minimum three days of hospitalisation or brain and spinal cord injuries.

    Do you know?

    The ‘golden hour’ has been defined as ‘the time period lasting one hour following a traumatic injury during which there is the highest likelihood of preventing death by providing prompt medical care.

     

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  • Industrial Sector Updates – Industrial Policy, Ease of Doing Business, etc.

    [pib] Industrial Park Ratings System (IPRS) Report

    The Department for Promotion of Industry and Internal Trade (DPIIT) has released the Industrial Park Ratings System Report.

    Industrial Park Ratings System (IPRS)

    • The IPRS pilot exercise was launched in 2018 with an objective of enhancing industrial infrastructure competitiveness and supporting policy development for enabling industrialization across the country.
    • The IPRS report is an extension of the India Industrial Land Bank which features more than 4,400 industrial parks in a GIS-enabled database.
    • It seeks to help investors identify their preferred location for investment.
    • With this report, the investors can even remotely refer to this report to identify the suitable investable land area, as per the various parameters of infrastructure, connectivity, business support services and environment and safety standards.

    Highlights of the report

    • 41 Industrial Parks have been assessed as “Leaders” in the Industrial Park Ratings System Report released by DPIIT.
    • 90 Industrial Parks have been rated as under the Challenger category while 185 have been rated as under “Aspirers”.
    • These ratings are assigned on the basis of key existing parameters and infrastructure facilities etc.

     

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  • GI(Geographical Indicator) Tags

    [pib] GI tagged sweet dish Mihidana

    The first consignment of GI-tagged sweet dish Mihidana sourced from Bardhaman, West Bengal has been exported to the Kingdom of Bahrain.

    About Mihidana

    • Mihidana, described as the micro cousin of the traditional Boondi, is derived from two words, Mihi meaning fine, and Dana, meaning grain.
    • The dessert is made from powdered Kaminibhog, Gobindobhog and basmati rice, mixed with a small amount of gram flour and saffron for a golden colour.
    • It is then blended with water by hand till its colour lightens.
    • This mix is then poured through a brass ladle with tiny holes into a pot of ghee and deep-fried.
    • The fine fried small rice-like grains are dipped in sugar syrup and drained once soaked.

    Back2Basics: Geographical Indication

    • A GI is a sign used on products that have a specific geographical origin and possess qualities or a reputation that are due to that origin.
    • Nodal Agency: Department for Promotion of Industry and Internal Trade (DPIIT), Ministry of Commerce and Industry
    • India, as a member of the World Trade Organization (WTO), enacted the Geographical Indications of Goods (Registration and Protection) Act, 1999 w.e.f. September 2003.
    • GIs have been defined under Article 22 (1) of the WTO Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) Agreement.
    • GI is granted for a term of 10 years in India. As of today, more than 300 GI tags has been allocated so far in India (*Wikipedia).
    • The tag stands valid for 10 years.

     

    Answer this PYQ in the comment box:

    Q.Which of the following has/have been accorded ‘Geographical Indication’ status?

    1. Banaras Brocades and Sarees
    2. Rajasthani Daal-Bati-Churma
    3. Tirupathi Laddu

    Select the correct answer using the code given below:

    (a) 1 only

    (b) 2 and 3 only

    (c) 1 and 3 only

    (d) 1, 2 and 3

    Post your answers here.

     

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  • Industrial Sector Updates – Industrial Policy, Ease of Doing Business, etc.

    Lessons from the death of the ease of doing business index

    Context

    The Ease of Doing Business Index (EoDB) came under attack on grounds that its data was modified in response to pressure from countries like China and Saudi Arabia. As a result of an independent audit, the index has now been abandoned by the Bank.

    Methodology used in EoDB ranking

    • World Bank researchers developed the EoDB ranking system under the assumption that better laws and regulatory frameworks would increase the ease of doing business and improve economic performance.
    • It collected data from respondents in various countries regarding existing laws and regulations on multiple dimensions, validated them through internal scrutiny, and then combined them into an overall index that allowed us to rank countries.
    • Each dimension was weighted equally and added up to create a scale.

    India specific issues with the EoDB ranking

    • If we want to create an internationally comparable index, we must ask similar questions.
    • Difference in level of development not taken into account: Yet, many of these questions may not be locally salient in economies at different levels of development.
    • For example, EoDB asked questions about the ease of getting an electric connection.
    • However, it is not getting a connection that is the problem, rather the reliability of electricity supply that hampers Indian industries.
    • In addition, most of the questions focused on hypothetical cases about limited liability companies.
    •  However, the World Bank’s own enterprise survey shows that 63 per cent of Indian enterprises are sole proprietorships and only 14 per cent are limited partnerships.
    •  Focusing on protecting minority owners’ rights in this tiny segment of Indian industries and using it to rank the business climate in India does not seem particularly useful.
    • The index placed tremendous faith in formalised systems while simultaneously disdaining bureaucratic structures embedded in this formalisation.

    Why EoDB ranking was so significant?

    • A bigger problem is that EoDB had acquired such power that countries competed to improve their rankings.
    • Countries assume that their EoDB ranking will attract foreign investors.
    • Empirical evidence about this presumed impact is questionable.
    • There is indeed some evidence that the score on EoDB is associated with FDI, but this association exists mainly for more affluent countries.
    •  For instance, in 2020, China was the largest recipient of FDI despite ranking 85th on the EoDB.
    • One of the less visible parts of the EoDB exercise was the underlying political message.
    • Regulation, often treated synonymously with bureaucratic hurdles, is bad, and abandoning regulations will bring positive results.

    Way forward

    • Should we try to reform the index or give up on it? The decision rests on the answer to two questions.
    • First, are there universally acceptable standards of sound economic practices that are applicable and measurable across diverse economies?
    • Second, if the indices are so powerful, should their construction be left to institutions like the World Bank that bring not just knowledge but also wield the heft of global economic power?

    Consider the question “What are the advantages associated with Ease of Doing Business ranking? What are the issues with it?” 

    Conclusion

    The presumed economic consequences, as well as political benefits associated with improving the rankings, encouraged many countries to try and “game” the system by making superficial improvements on indicators that are being measured and, when that failed, by putting explicit pressure on the World Bank research team.

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  • Forest Conservation Efforts – NFP, Western Ghats, etc.

    Taproots to help restore India’s fading green cover

    This op-ed tries to establish a fair link between forest cover and population dependency on it.

    A decline in Forest Cover

    • The State of the World’s Forests report 2020, says that since 1990, around 420 million hectares of forest have been lost through deforestation, conversion and land degradation.
    • Nearly 178 million hectares have decreased globally due to deforestation (1990-2020).
    • India lost 4.69 MHA of its forests for various land uses between 1951 to 1995.

    Various reasons

    • Despite various international conventions and national policies in place to improve green cover, there is a decline in global forest cover.
    • Dependence on forests by nearly 18% of the global human population has put immense pressure on ecosystems; in India, this has resulted in the degradation of 41% of its forests.

    Why conserve forests?

    • Covering nearly 30% land surface of the earth, forests around the globe provide a wide variety of ecosystem services and support countless and diverse species.
    • They also stabilise the climate, sequester carbon and regulate the water regime.

    Need for restoration

    • Restoration in laymen’s terms is bringing back the degraded or deforested landscape to its original state by various interventions to enable them to deliver all the benefits.
    • Building and maintaining activities help to improve ecological functions, productivity and create resilient forests with multifarious capabilities.
    • India’s varied edaphic, climatic and topographic conditions are spread over 10 bio-geographical regions and four biodiversity hotspots, sheltering 8% of the world’s known flora and fauna.

    India’s dependency on forest resources

    • Out of its 21.9% population living under the poverty line, nearly 275 million people including local tribals depend on the forest for subsistence.
    • The intricate link between poverty and environmental degradation was first highlighted by India at the first UN global conference on the human environment in Stockholm.
    • Though India’s increasing economic growth is helping to eliminate poverty, there is continued degradation and a growing scarcity of natural resources.
    • Further, encroachment of nearly 1.48 MHA of forest and grazing in nearly 75% of forest area is also linked to the livelihood of local communities.
    • The participation of local communities with finances for incentives and rewards is essential to redress this complex riddle.

    Strategies adopted by India

    Ans. Bonn Challenge

    • To combat this, India joined the Bonn Challenge with a pledge to restore 21 MHA of degraded and deforested land which was later revised to 26 MHA to be restored by 2030.
    • The first-ever country progress report under the Bonn Challenge submitted by India by bringing 9.8 million hectares since 2011 under restoration is an achievement.
    • However, continued degradation and deforestation need to be tackled effectively to achieve the remaining target of restoration by addressing various challenges.

    Key challenges

    • Local ecology with a research base: forest restoration and tree planting are leading strategies to fight global warming by way of carbon sequestration.
    • However, planting without considering the local ecology can result in more damage.
    • Similarly, planting a forest in the wrong places such as savannah grasslands could be disastrous for local biodiversity.

    Best strategy: Natural Forest Restoration

    • Luckily recent research has shown that naturally regenerated forests tend to have more secure carbon storage.
    • Being less tech-sensitive, cost-effective and conserving more biodiversity, natural forest restoration is becoming more widely accepted.

    Limitations to India

    • Nearly 5.03% of Indian forests are under protection area (PA) management needing specific restoration strategies.
    • The remaining areas witness a range of disturbances including grazing, encroachment, fire, and climate change impacts that need area-specific considerations.
    • Further, much of the research done so far on restoration is not fully compatible with India’s diverse ecological habitats hence warranting due consideration of local factors.
    • The involvement of multiple stakeholders in forest restoration is bound to cause a conflict of interests among different stakeholders; along with low priority and insufficient funding, it becomes even more challenging.

    Policy measures

    • There have been remarkable initiatives to involve local people in the protection and development of forests by forming joint forest management committees (JFMC).
    • However, a review of their functionality and performance is essential to make them more dynamic and effective to scale up their involvement.
    • Therefore, negotiations with a wide range of stakeholders including these committees for resolving conflicts and fulfilling restoration objectives are a must and a challenging feat to reach a suitable trade-off.

    Way forward

    • Adequate financing is one of the major concerns for the success of any interventions including restoration.
    • The active approach of restoration which includes tree planting and the involvement of communities seeks incentives and rewards and make the whole affair quite cost-intensive.
    • The contribution of corporates in restoration efforts so far has been limited to 2% of the total achievement.
    • Hence, alternate ways of financing such as involving corporates and dovetailing restoration activities with ongoing land-based programmes of various departments can help to make it easy for operation.
    • Apart from these specific challenges, the common barriers to restoration as identified globally also need critical review before placing the required methodologies and area-specific strategies in place.

    Conclusion

    • Active engagement of stakeholders including non-governmental organizations, awareness and capacity building of stakeholders with enabling policy interventions and finance can help a lot to achieve restoration objectives for India.
    • The need of the hour is an inclusive approach encompassing these concerns with the required wherewithal.

     

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  • Forest Conservation Efforts – NFP, Western Ghats, etc.

    Govt moots easy clearance for Forest Land use

    The government has proposed absolving agencies involved in national security projects and border infrastructure projects from obtaining prior forest clearance from the Centre as part of amendments to the existing Forest Conservation Act (FCA).

    About Forest (Conservation) Act, 1980

    • The FCA is the principal legislation that regulates deforestation in the country.
    • It prohibits the felling of forests for any “non-forestry” use without prior clearance by the central government.
    • The clearance process includes seeking consent from local forest rights-holders and from wildlife authorities.
    • The Centre is empowered to reject such requests or allow it with legally binding conditions.
    • In a landmark decision in 1996, the Supreme Court had expanded the coverage of FCA to all areas that satisfied the dictionary definition of a forest; earlier, only lands specifically notified as forests were protected by the enforcement of the FCA.

    What is the proposed amendment?

    • The proposed amendment is part of a larger rationalizing of existing forest laws for infrastructure projects.
    • The act was regressively interpreted over the right of way of railways, highways.
    • As of today a landholding agency (Rail, NHAI, PWD, etc) is required to take approval under the Act as well as pay stipulated compensatory levies.
    • They are required to pay Net Present Value (NPV), Compensatory Afforestation (CA), etc. for use of such land which was originally been acquired for non-forest purposes.

    Other proposals

    • The Environment Ministry has proposed provisions for penal compensation to make good for the damages already done to trees in forest land.
    • The document also proposes removing zoos, safaris, Forest Training infrastructures from the definition of “non-forestry” activities.
    • The current definition restricts the way money collected as part of compensatory cess can be spent towards forest conservation purposes.

    Previous attempts made

    • Previous attempts to amend acts linked to forest laws have been controversial.
    • There was a plan to amend the Indian Forest Act, 1927, that deals with the rights of forest dwellers, in an attempt to address contemporary challenges to the country’s forests.
    • The draft law had been sent to key forest officers in the States for soliciting comments and objections.
    • It drew flak from activists as well as tribal welfare organizations.
    • The government withdrew the draft and has said that a newer updated version was on the anvil.

     

    Try answering this PYQ

    Consider the following statements:

    1. As per recent amendment to the Indian Forest Act, 1927, forest dwellers have the right to fell the bamboos grown on forest areas.
    2. As per the Scheduled Tribes and Other Traditional Forest Dwellers (Recognition of Forest Rights) Act, 2006, bamboo is a minor forest produce.
    3. The Scheduled Tribes and Other Traditional Forest Dwellers (Recognition of Forest Rights) Act, 2006 allows ownership of minor forest produce to forest dwellers.

    Which of the statements given above is / are correct?

    (a) 1 and 2 only

    (b) 2 and 3 only

    (c) 3 only

    (d) 1, 2 and 3

     

    Post your answers here.

     

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  • Cyber Security – CERTs, Policy, etc

    What is Border Gateway Protocol (BGP) ?

    The outages at Facebook, WhatsApp and Instagram occurred because of a problem in the company’s domain name system. At the heart of it was a BGP or Border Gateway Protocol issue.

    What is BGP?

    • Simply put, it is the protocol that runs the internet or makes it work.
    • Since the internet is a network of networks, BGP is the mechanism that bounds it together.
    • When the BGP doesn’t work, internet routers can’t really figure out what to do and that leads to the internet not working.
    • The routers — big ones — keep up on updating other possible routes that are used to deliver network packets to the last possible source.
    • In this case, Facebook platforms were the last point of destination and BGP problem meant Facebook was unable to tell other networks know that it was on the internet.

    How does it work?

    • The BGP is like an entity that is responsible for creating and more importantly updating maps that lead you to sites like Google, Facebook or YouTube.
    • So if someone is responsible for making and updating the map, and they make a mistake, then the traffic — or users — will not end up reaching that place.

    How did a BGP issue affect Facebook?

    • A BGP update message informs a router of any changes you’ve made to a prefix advertisement or entirely withdraws the prefix.
    • There were a lot of routing changes from Facebook last night and then routes were withdrawn, Facebook’s Domain Name Server went offline.

    Role of DNS

    • DNS is the phonebook of the Internet.
    • People access information online through domain names — timesofindia.com or facebook.com.
    • Internet browsers use IP or Internet Protocol addresses and what DNS does is that it translates domain names to IP addresses to browsers can load Internet resources.
    • If DNS is the internet’s phone book, BGP is its postal service.
    • When a user enters data in the internet, BGP determines the best available paths that data could travel.

     

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  • Nobel and other Prizes

    Physiology Nobel for work on temperature and touch

     

    U.S. scientists David Julius and Ardem Patapoutian have won the Nobel Medicine Prize for discoveries on receptors for temperature and touch.

    Who are the Laureates?

    • David Julius and Ardem Patapoutian, working independently in the United States, made a series of discoveries in the late 1990s and early 2000s.
    • They figured out the touch detectors in our body and the mechanism through which they communicate with the nervous system to identify and respond to a particular touch.

    What did they discover?

    • They discovered the molecular sensors in the human body that are sensitive to heat, and to mechanical pressure, and make us “feel” hot or cold, or the touch of a sharp object on our skin.
    • n 1997, Dr. Julius and his team published a paper in Nature detailing how capsaicin, or the chemical compound in chili peppers, causes the burning sensation.
    • They created a library of DNA fragments to understand the corresponding genes and finally discovered a new capsaicin receptor and named it TRPV1.
    • This discovery paved the way for the identification of many other temperature-sensing receptors.
    • They identified another new receptor called TRPM8, a receptor that is activated by cold. It is specifically expressed in a subset of pain-and-temperature-sensing neurons.
    • They identified a single gene PIEZO2, which when silenced made the cells insensitive to the poking. They named this new mechanosensitive ion channel Piezo1.

    How do they work?

    • The human ability to sense heat or cold and pressure is not very different from the working of the many detectors that we are familiar with.
    • When something hot, or cold, touches the body, the heat receptors enable the passage of some specific chemicals, like calcium ions, through the membrane of nerve cells.
    • It’s like a gate that opens up on a very specific request. The entry of the chemical inside the cell causes a small change in electrical voltage, which is picked up by the nervous system.
    • There is a whole spectrum of receptors that are sensitive to different ranges of temperature.
    • When there is more heat, more channels open up to allow the flow of ions, and the brain is able to perceive higher temperatures.

    Therapeutic implications

    • Breakthroughs in physiology have often resulted in an improvement in the ability to fight diseases and disorders. This one is no different.
    • There are receptors that make us feel pain. If these receptors can suppress, or made less effective, the person had felt less pain.
    • Chronic pain is present is a number of illnesses and disorders. Earlier, the experience of pain was a mystery.
    • But as we understand these receptors more and more, it is possible that we gain the ability to regulate them in such a way that the pain is minimized.

    [Note: We will compile all Nobel Prizes into a single post once all are awarded.]

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