💥UPSC 2026, 2027, 2028 UAP Mentorship (March Batch) + Access XFactor Notes & Microthemes PDF

Type: Prelims Only

  • Capital Markets: Challenges and Developments

    What are Global Depository Receipts (GDRs)?

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Global Depository Receipts (GDRs)

    Mains level: Not Much

    Central Idea: Tata Consumer Products has announced its decision to delist its global depository receipts (GDRs) from the London Stock Exchange and Luxembourg Stock Exchange.

    What are GDRs?

    • GDRs are financial instruments used by companies to raise capital from international investors.
    • They represent a bundle of shares in the company and are typically listed and traded on international stock exchanges.
    • GDRs provide a way for companies to access global capital markets and attract investments from foreign investors without directly listing their shares on multiple stock exchanges around the world.

    GDR Regulation in India

    • In India, GDRs can be issued by Indian companies that meet the eligibility criteria set by the SEBI.
    • SEBI sets guidelines and regulations for companies wishing to issue GDRs typically include the following:
    1. Listing: The company must be listed on a recognized stock exchange in India.
    2. Track Record: The company should have a track record of profitability for a certain period as specified by SEBI.
    3. Good Corporate Governance: The company must comply with corporate governance norms and disclose relevant financial and non-financial information.
    4. Regulatory Compliance: The company must comply with all applicable laws and regulations, including those related to securities and foreign exchange.
    5. Approval from Regulatory Authorities: The company needs to obtain necessary approvals from SEBI and other relevant authorities for the issuance of GDRs.

    Need for GDR

    • Capital Raising: GDRs offer a means for companies to raise capital from international investors, helping them finance investments, expansion projects, acquisitions, or debt repayment.
    • Global Investor Base: GDRs allow companies to access a diverse range of international investors, including institutional investors, hedge funds, and retail investors, thereby expanding their shareholder base.
    • Cost Efficiency: GDRs can be a cost-effective alternative to traditional methods of listing shares on multiple exchanges, as they enable companies to tap into global capital markets without the need for separate listings in different countries.
    • Simplified Trading and Settlement: GDRs facilitate easy trading and settlement for international investors, as they eliminate the need to navigate local market regulations and procedures.
    • Risk Mitigation: GDRs can provide a degree of risk mitigation for companies by reducing their exposure to local market fluctuations and volatility, as they offer access to a more diversified investor base.
    • Arbitrage Opportunities: GDRs can create arbitrage opportunities for investors who can exploit price discrepancies between the GDRs and the underlying shares listed on the domestic stock exchange.

    Benefits offered

    • Access to Global Capital: GDRs enable Indian companies to access a larger pool of international capital and diversify their funding sources beyond domestic markets.
    • Increased Liquidity: Listing GDRs on international exchanges provides Indian companies with broader exposure and enhances the liquidity of their shares, as they become accessible to a wider range of investors.
    • Enhanced Global Visibility: GDRs help raise the profile of Indian companies on a global scale, increasing their visibility and attracting the attention of international investors and analysts.
    • Currency Diversification: GDRs can also provide an opportunity for Indian companies to diversify their exposure to foreign currencies, as GDRs are often denominated in a currency other than the company’s home currency.

     

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  • Water Management – Institutional Reforms, Conservation Efforts, etc.

    Arsenic Contamination in India

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Arsenic Poisoning

    Mains level: Not Much

    arsenic

    Central Idea: A recent peer-reviewed study suggests that even low levels of arsenic consumption can affect cognitive function in children, adolescents, and young adults.

    Arsenic Contamination

    • Arsenic is a highly toxic element naturally present in the environment.
    • Contaminated water, particularly groundwater, is a major source of arsenic exposure.
    • Long-term arsenic exposure can lead to various health issues, including cancer, skin lesions, cardiovascular disease, and negative impacts on cognitive development.

    Menace in India

    • Arsenic contamination in groundwater is one of the most crippling issues in the drinking water scenario of India.
    • According to the latest report of the Central Ground Water Board (CGWB), 21 states across the country have pockets with arsenic levels higher than the BIS stipulated permissible limit of 0.01 milligram per litre (mg/l).
    • The states along the Ganga-Brahmaputra-Meghna (GBM) river basin — Uttar Pradesh, Bihar, Jharkhand, West Bengal and Assam — are the worst affected by this human-amplified geogenic occurrence.
    • In India, arsenic contamination was first officially confirmed in West Bengal in 1983.
    • Close to four decades after its detection, the scenario has worsened.
    • About 9.6 million people in West Bengal, 1.6 million in Assam, 1.2 million in Bihar, 0.5 million in Uttar Pradesh and 0.013 million in Jharkhand are at immediate risk from arsenic contamination in groundwater.

    Key findings of the recent study

    (1) Arsenic impact on behaviour

    • The study found that individuals exposed to arsenic had reduced grey matter and weaker connections within key regions of the brain associated with cognitive functions.
    • Chronic exposure to arsenic could have significant consequences at a population level, leading to increased school failures, diminished economic productivity, and higher risks of criminal and antisocial behavior.

    (2) Arsenic Exposure and Socioeconomic Factors

    • As previous studies have shown, arsenic exposure is particularly harmful to the poor.
    • The recent study reaffirms that economically and nutritionally disadvantaged individuals experience greater cognitive impairment from arsenic exposure.
    • The impact of arsenic on impairing cognition is more pronounced at a collective level rather than at an individual level.

    Government Initiatives to address Arsenic Contamination

    • Governments in Bihar and West Bengal have taken steps to address arsenic contamination since the 1990s.
    • Strategies include promoting piped water access, installing arsenic removal plants, and encouraging groundwater extraction from deeper aquifers with lower arsenic levels.
    • The goal is to minimize arsenic exposure and mitigate its health impacts in affected regions.

    Possible solutions

    Some of the management options include

    • Uses of surface water sources
    • Exploring and harnessing alternate arsenic-free aquifer
    • Removal of arsenic from groundwater using arsenic treatment plants/filters
    • Adopting rainwater harvesting/ watershed management practices.

     

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  • Banking Sector Reforms

    Credit cards put under Liberalised Remittance Scheme (LRS)

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Liberalised Remittance Scheme (LRS)

    Mains level: Not Much

    Central Idea: The Centre has amended rules under Foreign Exchange Management Act (FEMA) Rules, bringing international credit card spends under the Liberalised Remittance Scheme (LRS).

    Changes introduced

    • Credit card spends outside India now fall under the LRS, allowing for the application of a higher TCS rate.
    • The amendment removes the exclusion of credit card transactions from the LRS, which was previously covered under Rule 7 of the Foreign Exchange Management (Current Account Transaction) Rules, 2000.
    • The changes do not apply to payments for the purchase of foreign goods/services from India.

    What is Liberalised Remittance Scheme (LRS)?

    • LRS is a facility provided by the Reserve Bank of India (RBI) to resident individuals to remit funds abroad for permitted current or capital account transactions or a combination of both.
    • The scheme was introduced in 2004 and has been periodically reviewed and revised by the RBI.
    • Under the scheme, resident individuals can remit up to a certain amount in a financial year for permissible transactions including education, travel, medical treatment, gifts, and investments in equity and debt securities, among others.
    • The limit for LRS is currently set at USD 250,000 per financial year.

    Eligibility for LRS

    • LRS is open to everyone including non-residents, NRIs, persons of Indian origin (PIOs), foreign citizens with PIO status and foreign nationals of Indian origin.
    • The Scheme is NOT available to corporations, partnership firms, Hindu Undivided Family (HUF), Trusts etc.

    Benefits provided by LRS

    • LRS is an easy process that anyone can use to transfer money between two countries.
    • It’s especially useful for businesses because they can use it to transfer funds to India, and investors can receive their investments back home.
    • LRS also has some added benefits, like fast transfer timing and no issues with exchange rates.

    Concerns with credit card spends

    • The amendment aims to achieve parity between the usage of credit and debit cards, which were already covered under the LRS.
    • Instances of disproportionately high LRS payments compared to disclose incomes prompted the amendment.
    • Business visits of employees, where costs are borne by the employer, are not covered under the LRS.
    • The data collected from major money remitters under the LRS indicated that international credit cards were being issued with limits exceeding the prescribed norm.

    Exclusions and impact of the Scheme

    • The government assured that the LRS scheme would not cover genuine business visits abroad by employees.
    • The imposition of a 20% tax collection on source (TCS) for foreign remittances would primarily affect tour travel packages, gifts to non-residents, and domestic high net-worth individuals investing in assets like real estate, bonds, and stocks outside India.
    • The Ministry emphasized that the 5% TCS levied on medical or education expenses abroad, allowed up to ₹7 lakh per year, and would remain unchanged.
  • RBI Notifications

    RBI regulations on Green Deposits

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Green Deposits

    Mains level: Not Much

    Central Idea: The Reserve Bank of India (RBI) has introduced a regulatory framework to govern the acceptance of green deposits by banks, ensuring transparency and accountability in their investments.

    What are Green Deposits?

    • Green deposits are financial products offered by banks that are similar to regular deposits, but the money received is specifically earmarked for environmentally friendly projects.
    • These deposits support projects aimed at combating climate change, such as renewable energy initiatives, while avoiding investments in activities that harm the environment, like fossil fuel projects.
    • They are part of a broader range of financial products, including green bonds and green shares that enable investors to contribute to environmentally sustainable projects.

    Regulatory framework for accepting Green Deposits

    • The RBI’s framework mandates that banks establish a set of rules or policies, approved by their respective Boards, to guide the investment of green deposits.
    • These rules must be made public on the banks’ websites, ensuring transparency and enabling customers to make informed decisions.
    • Banks are required to disclose information on the amount of green deposits received, how these funds are allocated to different green projects, and the environmental impact of such investments.
    • To verify the banks’ claims and the sustainability credentials of the projects, a third-party is appointed to conduct independent verification.

    Sectors eligible for green deposits

    • The RBI has identified a list of sectors classified as sustainable, which are eligible to receive green deposits.
    • These sectors include renewable energy, waste management, clean transportation, energy efficiency, and afforestation.
    • Banks are prohibited from investing green deposits in sectors considered detrimental to the environment, such as fossil fuels, nuclear power, tobacco, gambling, palm oil, and hydropower generation.

    Addressing greenwashing

    • Greenwashing refers to the practice of making misleading claims about the positive environmental impact of an activity or investment.
    • The RBI’s regulatory framework aims to prevent greenwashing in the banking sector by ensuring that the actual impact of green deposits is accurately represented.
    • By requiring transparency, disclosure, and third-party verification, the framework aims to protect customers from deceptive practices and ensure genuine environmental benefits.

    Impact and controversies

    • Depositors who prioritize environmental concerns may find satisfaction in investing their money in environmentally sustainable products like green deposits.
    • However, some critics argue that green investment products may primarily serve to make investors feel good without generating significant environmental benefits.
    • Additionally, the range of projects available for investment through green deposits may be limited, posing challenges in achieving broad environmental impact.

    Key challenge: Assessing environmental sustainability

    • Evaluating the true environmental sustainability of a project can be challenging in a complex world with interconnected systems and second-order effects that are difficult to anticipate.
    • It is essential to consider the indirect consequences and long-term effects of actions to determine if a project genuinely contributes to environmental sustainability.
    • Uncertainty surrounding the actual environmental impact of green projects highlights the need for rigorous evaluation and ongoing monitoring to ensure the desired outcomes are achieved.

     

     

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  • Innovations in Sciences, IT, Computers, Robotics and Nanotechnology

    Quantum Biology: Unveiling the Quantum Secrets of Life

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Quantum Biology

    Mains level: Not Much

    biology

    Central Idea: The article introduces the concept of quantum biology, which explores the influence of quantum effects on living systems.

    Nature and Quantum Mechanics

    • Quantum effects refer to phenomena that occur between atoms and molecules that cannot be explained by classical physics.
    • Quantum mechanics, which governs the behavior of objects at atomic scales, differs from classical mechanics, leading to counterintuitive phenomena like particle tunnelling and superposition.

    Quantumness in Biology

    • Quantum biology is an emerging field that explores the role of quantum mechanics in biological processes and living systems.
    • It investigates how quantum phenomena and effects, which typically occur at atomic and subatomic scales, influence and contribute to the functioning and behavior of biological systems.
    • It aims to uncover and understand the quantum nature of biological molecules, processes, and interactions.
    • It seeks to study how quantum mechanics may impact various biological phenomena such as photosynthesis, enzyme reactions, and navigation in birds.

    Evidence of Quantum Effects in Biology

    • Research on chemical reactions in biomolecules like proteins and genetic material suggests the influence of quantum effects.
    • Nanoscopic quantum effects can drive macroscopic physiological processes, including enzyme activity, sensing magnetic fields, cell metabolism, and electron transport.

    Studying Quantum Biology

    • Studying quantum effects in biology requires tools to measure short time scales, small length scales, and subtle differences in quantum states.
    • Researchers can apply tailored magnetic fields to control the spins of electrons, influencing physiological processes that respond to magnetic fields.

    Potential applications

    • Therapeutic devices: Understanding and fine-tuning quantum properties in nature could lead to non-invasive, remotely controlled therapeutic devices accessible through mobile phones.
    • Bio-manufacturing: Electromagnetic treatments based on quantum principles could be used for disease prevention and treatment, such as brain tumors, as well as in bio-manufacturing.

    Scope quantum biology’ study

    • Multi-disciplinary: Quantum biology is an interdisciplinary field that brings together researchers from various disciplines, including quantum physics, biophysics, medicine, chemistry, and biology.
    • Many applications: Collaboration and cross-disciplinary research are crucial for advancing quantum biology and unlocking its transformative potential in biology, medicine, and technology.

     

    Facts for Prelims

    Superposition: A quantum phenomenon where particles can exist in multiple states simultaneously until measured or observed, in contrast to classical physics where objects have definite properties.

    Spins: Quantum properties of electrons that define their interaction with magnetic fields, analogous to the way charge defines their interaction with electric fields.

    Deterministic Codebook: A comprehensive understanding of the relationship between quantum causes and physiological outcomes, providing a guide for mapping quantum phenomena to specific biological effects.

     

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  • Innovations in Sciences, IT, Computers, Robotics and Nanotechnology

    DoT develops Facial Recognition Tool ‘ASTR’

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: ASTR, AI

    Mains level: Not Much

    astr

    Central Idea: The Department of Telecommunications (DoT) has developed an artificial-intelligence-based facial recognition tool called Artificial Intelligence and Facial Recognition powered Solution for Telecom SIM Subscriber Verification (ASTR).

    What is ASTR?

    • ASTR is designed to check subscriber databases of telecom operators to identify multiple connections associated with the same person.
    • The goal of ASTR is to detect and block fraudulent mobile connections, thereby reducing cyber frauds.

    Development of ASTR

    • In 2012, DoT issued an order requiring telecom operators to share their subscriber database, including users’ pictures, with the department.
    • These images serve as the core database for facial recognition using ASTR.
    • The ASTR project was conceptualized and designed by the DoT’s unit in Haryana between April 2021 and July 2021.
    • A pilot project was conducted in Haryana’s Mewat region to test the feasibility of ASTR, where a significant number of fraudulent SIMs were detected.

    How ASTR works?

    • ASTR uses convolutional neural network (CNN) models to encode human faces in subscribers’ images, accounting for various factors like face tilt, angle, image opaqueness, and dark color.
    • A face comparison is performed for each face against all faces in the database, grouping similar faces under one directory.
    • ASTR considers two faces to be identical if they match to a minimum extent of 97.5%.
    • It can detect all SIMs associated with a suspected face within 10 seconds from a database of 1 crore (10 million) images.
    • After matching faces, ASTR’s algorithm utilizes “fuzzy logic” to find approximate matches for subscriber names, considering variations, typographical errors, and related results.

    Impact and Results

    • In the first phase, ASTR analyzed over 87 crore (870 million) mobile connections and detected more than 40 lakh (4 million) cases of people using a single photograph to obtain multiple connections.
    • After verification, over 36 lakh (3.6 million) connections were discontinued by telecom operators.
    • The list of fraudulent connections is also shared with banks, payment wallets, and social media platforms to disengage these numbers from their respective platforms.
    • WhatsApp collaborated with the government to disable accounts created using such numbers, and similar efforts are being made with other social media platforms.

    Facts for Prelims

    Convolutional Neural Network (CNN): A type of deep learning algorithm commonly used for image recognition tasks, where it extracts features and patterns from images by applying convolution operations.

    Fuzzy Logic: A form of logic that deals with approximate or qualitative reasoning rather than strict binary true/false values. In the context of ASTR, it is used to find similarity or approximate matches for subscriber names, accounting for variations and typographical errors.

     

     

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  • Russian Invasion of Ukraine: Global Implications

    India’s export of Russian oil to West

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Vacuum gas oil (VGO)

    Mains level: Reprocessing Russian oil

    oil

    Central Idea

    • The article discusses India’s increased imports of Russian oil and the potential circumvention of sanctions imposed on Russian oil products.

    Why in news?

    • An EU parliamentarian accused India of profiting from cheaply bought Russian oil and indirectly supporting the Russian economy.
    • India justified its purchase by emphasizing its energy demands and the challenges of higher prices due to its reliance on energy imports and significant poverty levels.

    Reasons: Sanctions against Russian Oil

    • After Russia’s invasion of Ukraine, Western countries and Europe aimed to reduce their dependency on Russian energy imports to weaken the Russian economy.
    • Measures were taken, such as Germany suspending the launch of the Nord Stream natural gas pipeline and Canada and the US banning the import of Russian crude oil.
    • Stricter sanctions were imposed on Russia, including a “price cap” from trading Russian oil above $60 per barrel.
    • The price cap aimed to cripple Moscow’s economy and limit its ability to fund the war in Ukraine.
    • However, Russia increased its oil exports to India and China as a response.

    India’s role in meeting West’s energy demand

    • India, exempt from the sanctions on Russian oil, has seen a significant increase in fuel imports from Russia, which is then refined and supplied to Europe and the US.
    • The refined oil from Russian crude, once processed in India, is not considered of Russian origin.
    • India’s oil imports have helped it meet its own energy demands and also assist Western nations facing energy crises due to the Russia-Ukraine conflict.
    • India has become a net exporter of refined petroleum products, supplying the West to alleviate current energy shortages.

    Impact of Indian imports on Western markets

    • Indian refiners have ramped up exports of refined petroleum products, including diesel and vacuum gas oil (VGO), to Europe and the US.
    • VGO is a feedstock in the refining process that can be further processed to produce gasoline, diesel, and other fuel products.
    • Diesel exports to Europe from India have increased by 12-16% in the last fiscal year.
    • The US has become a major recipient of Indian VGO shipments, receiving 11,000-12,000 barrels per day (bpd) or 65-81% of India’s VGO exports.
    • These exports from India have helped ease the energy tightness and supply constraints in Western markets.

     

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  • Industrial Sector Updates – Industrial Policy, Ease of Doing Business, etc.

    Govt doubles outlay on PLI for IT hardware

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Production Linked Incentive (PLI) scheme

    Mains level: Not Much

    Central Idea

    PLI Scheme for IT Hardware

    • The PLI scheme for IT hardware was initially introduced in March 2021.
    • It provides incentives of over 4% for incremental investment in domestic manufacturing for eligible companies, such as Dell and Flextronics.
    • The scheme aims to boost domestic manufacturing, increase exports, and make India a prominent player in the IT hardware sector.
    • The scheme will have a tenure of six years, providing a long-term incentive for eligible companies to invest in domestic IT hardware manufacturing.

    Growth in indigenous IT hardware

    • The government highlighted the growth of electronics manufacturing in India.
    • There is a 17% compound annual growth rate over the past 8 years and a production benchmark of $105 billion, including $11 billion in mobile phone exports.

    New changes introduced

    • The budgetary outlay for the PLI scheme for IT hardware manufacturing has been set at ₹17,000 crore.
    • The incentive rate has been increased to 5%, offering a higher benefit to companies investing in domestic manufacturing.
    • An additional optional incentive has been introduced for using domestically produced components, although the specific rates of these incentives are not specified.
    • If the optional incentives are utilized as intended, the total incentive under the scheme could amount to 8-9%.

    Achievements in Telecom hardware manufacturing

    • Telecom hardware manufacturing has surpassed the projected ₹900 crore and reached ₹1,600 crore.
    • Some Indian companies have become significant exporters of complex radio equipment worldwide.

     

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  • Monsoon Updates

    Monsoon onset in Kerala on June 4

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Monsoon terminologies

    Mains level: Not Much

    monsoon

    Central Idea: The monsoon is likely to set in over Kerala with a “slight delay” on June 4, the India Meteorological Department (IMD) said. The usual onset date over Kerala is June 1, within a seven-day window.

    What does the “Onset of Monsoon” mean?

    • The onset of the monsoon over Kerala marks the beginning of the four-month, June to September southwest monsoon season over India.
    • It brings more than 70 per cent of the country’s annual rainfall.
    • It marks a significant transition in the large-scale atmospheric and ocean circulations in the Indo-Pacific region.
    • The IMD announces it only after certain newly defined and measurable parameters, adopted in 2016, are met.
    • The onset is a significant day in India’s economic calendar.

    How does IMD predict the monsoon?

    • Broadly, the IMD checks for the consistency of rainfall over a defined geography, its intensity, and wind speed:
    1. Rainfall: The IMD declares the onset of the monsoon if at least 60% of 14 designated meteorological stations in Kerala and Lakshadweep record at least 2.5 mm of rain for two consecutive days at any time after May 10.
    2. Wind field: The depth of westerlies should be upto 600 hectopascal (1 hPa is equal to 1 millibar of pressure) in the area bound by the equator to 10ºN latitude, and from longitude 55ºE to 80ºE. The zonal wind speed over the area bound by 5-10ºN latitude and 70-80ºE longitude should be of the order of 15-20 knots (28-37 kph) at 925 hPa.
    3. Heat: The INSAT-derived Outgoing Longwave Radiation (OLR) value (a measure of the energy emitted to space by the Earth’s surface, oceans, and atmosphere) should be below 200 watt per sq m (wm2) in the box confined by 5-10ºN latitude and 70-75ºE latitude.
    • The onset is not officially declared until the prescribed conditions (above) are met.

    Factors considered by IMD

    • The IMD uses a specialised model that forecasts the arrival dates within a four-day window.
    • It uses six predictors:
    1. Minimum temperatures over northwest India
    2. Pre-monsoon rainfall peak over south Peninsula
    3. Outgoing long-wave radiation (OLR) over the South China Sea
    4. Lower tropospheric zonal wind over the southeast Indian Ocean
    5. Upper tropospheric zonal wind over the east equatorial Indian Ocean, and
    6. OLR over the southwest Pacific region

    Back2Basics: Long Period Average (LPA)

    • The IMD predicts a “normal”, “below normal”, or “above normal” monsoon in relation to a benchmark “long period average” (LPA).
    • The LPA of rainfall is the rainfall recorded over a particular region for a given interval (like month or season) average over a long period like 30 years, 50 years, etc.
    • LPA refers to the average rainfall recorded from June to September for the entire country, the amount of rain that falls every year varies from region to region and from month to month.
    • The IMD’s prediction of a normal monsoon is based on the LPA of the 1971-2020 period, during which India received 87 cm of rain for the entire country on average.
    • It has in the past calculated the LPA at 88 cm for the 1961-2010 period, and at 89 cm for the period 1951-2000.

    Why LPA is needed?

    • The IMD records rainfall data at more than 2,400 locations and 3,500 rain-gauge stations.
    • Because annual rainfall can vary greatly not just from region to region and from month to month, but also from year to year within a particular region or month.
    • An LPA is needed to smooth out trends so that a reasonably accurate prediction can be made.
    • A 50-year LPA covers for large variations in either direction caused by freak years of unusually high or low rainfall, as well as for the periodic drought years.
    • It also takes into account the increasingly common extreme weather events caused by climate change.

    Range of normal rainfall

    The IMD maintains five rainfall distribution categories on an all-India scale. These are:

    1. Normal or near normal, when the percentage departure of actual rainfall is +/-10% of LPA, that is, between 96-104% of LPA;
    2. Below normal, when departure of actual rainfall is less than 10% of LPA, that is 90-96% of LPA;
    3. Above normal, when actual rainfall is 104-110% of LPA;
    4. Deficient, when departure of actual rainfall is less than 90% of LPA; and
    5. Excess, when the departure of actual rainfall is more than 110% of LPA.

     

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  • Health Sector – UHC, National Health Policy, Family Planning, Health Insurance, etc.

    India nears milestone with first indigenous Dengue Vaccine

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Dengue

    Mains level: Not Much

    dengue

    Central Idea: Serum Institute of India and Panacea Biotec have applied to the ICMR’s call for Expression of Interest for collaborative Phase-III clinical trials for an indigenous dengue vaccine.

    What is Dengue?

    Details
    Transmission Primarily transmitted through the bite of infected Aedes mosquitoes
    Virus and Serotypes Dengue virus belonging to the Flaviviridae family

    Four distinct serotypes: DENV-1, DENV-2, DENV-3, and DENV-4

    Symptoms High fever, severe headache, joint and muscle pain, rash, pain behind the eyes, mild bleeding
    Severe Dengue Progression to severe dengue can cause plasma leakage, bleeding, organ impairment
    Geographic Distribution Endemic in more than 100 countries, particularly in tropical and subtropical regions
    Incidence and Global Impact 100-400 million dengue infections occur annually globally, affecting healthcare systems and economies
    Vector and Breeding Sites Aedes aegypti mosquito breeds in stagnant water containers found near human dwellings
    Treatment No specific antiviral treatment available; supportive care, rest, fluid intake, symptom management
    Prevention and Control Reduce mosquito breeding sites, proper water storage, cleaning of water containers, use of insecticides

     

    Dengue Virus Disease and Global Impact

    • Dengue virus disease causes significant morbidity and mortality worldwide, with 2 to 2.5 lakh (200,000 to 250,000) cases reported annually in India.
    • The global incidence of dengue has increased dramatically, with over half of the world’s population at risk.
    • The World Health Organization (WHO) has identified dengue as one of the top ten global health threats in 2019.
    • Currently, there is no specific treatment for dengue, highlighting the urgent need for effective vaccines.

    Desirable Characteristics of a Dengue Vaccine

    The ICMR highlights the desirable characteristics of a dengue vaccine, including a-

    • Favorable safety profile
    • Protection against all four serotypes of dengue
    • Reduced risk of severe disease and death
    • Induction of a sustained immune response and
    • Effectiveness regardless of previous sero-status and age

     

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