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Type: Prelims Only

  • Pharma Sector – Drug Pricing, NPPA, FDC, Generics, etc.

    Price Monitoring and Resource Unit (PMRU)

    Prelims Only | Governance | Mains Paper 2: Health & Education

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Price Monitoring and Research Unit (PMRU)

    Mains level: Drug prices monotoring mechanisms in India

    The National Pharmaceutical Pricing Authority (NPPA) has set up price monitoring and resource unit (PMRU) in the UT of Jammu and Kashmir. With this J&K has become the 12th State/UT where the PMRU has been set up.

    Price Monitoring and Research Unit (PMRU)

    • It is a registered society set up for drug price monitoring.
    • PMRUs have already been set up by the drug price regulator NPPA in 11 states such as Kerala, Odisha, Gujarat, Rajasthan, Punjab, Haryana, Nagaland, Tripura, Uttar Pradesh, Andhra Pradesh and Mizoram.

    Its composition

    • The State Health Secretary would be the Chairman of the society and the Drugs Controller would be its member secretary.
    • Its members include a State government representative, representatives of private pharmaceutical companies, and those from consumer rights protection fora.
    • The society would also have an executive committee headed by the Drugs Controller.

    Terms of reference

    PMRU offers technical help to the State Drug Controllers and the NPPA to:

    • Monitor notified prices of medicines
    • Detect violation of the provisions of the DPCO
    • Look at price compliance
    • Collect test samples of medicines, and
    • Collect and compile market-based data of scheduled as well as non-scheduled formulations.

    Why need PMRU?

    • Pharma companies have been accused of overcharging prices of drugs in the scheduled category fixed by the DPCO and those outside its ambit too.
    • The suggestion to set up PMRUs was made against the backdrop of the lack of a field-level link between the NPPA and the State Drugs Controllers and State Drug Inspectors to monitor drug prices.

    Expected outcomes

    • The NPPA had fixed the prices of around 1,000 drugs and the unit would track if buyers were being overcharged.
    • It would also check if pharma companies were hiking the prices of non-scheduled drugs by more than 10% a year.
    • It will check if there is any shortage of essential medicines.

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  • RBI Notifications

    Fully Accessible Route (FAR)

    Prelims Only | Economics | Mains Paper 3: Effects Of Liberalization On The Economy, Changes In Industrial Policy and their effects on Industrial Growth

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Voluntary Retention Route (VRR), Fully Accessible Route (FAR)

    Mains level: Not Much

    The Reserve Bank of India (RBI) has introduced a separate channel, namely ‘Fully Accessible Route’ (FAR), to enable non-residents to invest in specified government bonds with effect from April 1.

    Fully Accessible Route (FAR)

    • The move follows the Union Budget announcement that certain specified categories of government bonds would be opened fully for non-resident investors without any restrictions.
    • Under FAR, eligible investors can invest in specified government securities without being subject to any investment ceilings.
    • This scheme shall operate along with the two existing routes, viz., the Medium Term Framework (MTF) and the Voluntary Retention Route (VRR).

    Benefits

    • This will substantially ease access of non-residents to Indian government securities markets and facilitate inclusion in global bond indices.
    • This would facilitate inflow of stable foreign investment in government bonds.

    Back2Basics

    Voluntary Retention Route (VRR)

    1. RBI had announced a separate scheme called VRR to encourage Foreign Portfolio Investors (FPIs) to undertake long-term investments in Indian debt markets.
    2. Under this scheme, FPIs have been given greater operational flexibility in terms of instrument choices besides exemptions from certain regulatory requirements.
    3. The details are as under:
    • The aggregate investment limit shall be ₹ 40,000 crores for VRR-Govt and ₹ 35,000 crores for VRR-Corp.
    • The minimum retention period shall be three years. During this period, FPIs shall maintain a minimum of 75% of the allocated amount in India.
    • Investment limits shall be available on tap for investments and shall be allotted by Clearing Corporation of India Ltd. (CCIL) on ‘first come first served’ basis.

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  • Zoonotic Diseases: Medical Sciences Involved & Preventive Measures

    Sodium Hypochlorite as Coronavirus disinfectant

    Prelims Only | Science Tech | Mains Paper 3: Achievements Of Indians In S&T

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Sodium hypochlorite, Bleaching Powder

    Mains level: Coronovirus outbreak and its mitigation

    In Uttar Pradesh, migrant workers travelling to their home states, or their belongings, were sprayed with a disinfectant, apparently to sanitise them.  The chemical in the spray was a sodium hypochlorite solution.

    Sodium hypochlorite

    • Sodium hypochlorite is commonly used as a bleaching agent, and also to sanitise swimming pools.
    • As a common bleaching agent, sodium hypochlorite is used for a variety of cleaning and disinfecting purposes.
    • It releases chlorine, which is a disinfectant. Large quantities of chlorine can be harmful.
    • The concentration of the chemical in the solution varies according to the purpose it is meant for.
    • A normal household bleach usually is a 2-10% sodium hypochlorite solution.
    • At a much lower 0.25-0.5%, this chemical is used to treat skin wounds like cuts or scrapes. An even weaker solution (0.05%) is sometimes used as a handwash.

    Note: The common bleaching powder is chemically referred to as Calcium hypochlorite and not Sodium hypochlorite.

    Is the chemical safe?

    • Sodium hypochlorite is corrosive and is meant largely to clean hard surfaces.
    • It is not recommended to be used on human beings, certainly not as a spray or shower. Even a 0.05% solution could be very harmful for the eyes.
    • A 1% solution can cause damage to the skin of anyone who comes in contact with it.
    • If it gets inside the body, it can cause serious harm to lungs.

    Does the chemical get rid of the novel coronavirus?

    • The WHO recommends homemade bleach solutions of about 2-10% concentration to clean hard surfaces to clear them of any presence of the novel coronavirus.
    • Cleaning hard surfaces with this solution can disinfect them not just from novel coronavirus but also help prevent flu, food born illnesses, and more.

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  • RBI Notifications

    Moratorium Option for payment of installments

    Prelims Only | Economics | Mains Paper 3: Indian Economy

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Moratorium Option

    Mains level: Not Much

    The RBI has permitted banks to allow moratorium of three months on payment of instalments in respect of all loans including home, car and personal loan among others.

    What exactly this moratorium means?

    • Both the loan principal and interest are covered under the moratorium. This applies to all loans outstanding on March 1.
    • We must note that this is a postponement, not a waiver.
    • RBI’s wordings clearly say that the tenor for term loans across the board may be shifted by three months. This essentially means the loan will end 3 months later than was originally slated.
    • Essentially, it means that payees won’t be treated as a defaulter even if you don’t pay your EMI till May 2020, and your CIBIL score won’t be affected.
    • This moratorium period will not come free, and since the interest will continue to accrue on the outstanding portion of the loan during the moratorium period, it may increase the customers’ burden significantly.

    The installments include:

    1. principal and/or interest components;
    2. bullet repayments;
    3. Equated Monthly installments;
    4. credit card dues

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  • Climate Change Impact on India and World – International Reports, Key Observations, etc.

    Earth Hour

    Prelims Only | Enviro & Biodiversity | Mains Paper 1: Important Geophysical Phenomena

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Earth Hour

    Mains level: Climate activism

    The Earth Hour, observed annually on the last Saturday of March, was recently celebrated.

    Earth Hour

    • Earth Hour is a worldwide movement organized by the World Wide Fund for Nature (WWF).
    • It is held annually encouraging individuals, communities, and businesses to turn off non-essential electric lights, for one hour, from 8:30 to 9:30 p.m. on a specific day towards the end of March as a symbol of commitment to the planet.
    • It was started as a lights-off event in Sydney, Australia, in 2007.

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  • Health Sector – UHC, National Health Policy, Family Planning, Health Insurance, etc.

    PM-CARES Fund

    Prelims Only | Governance | Mains Paper 2: Health & Education

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: PM-CARES Fund

    Mains level: Not Much

    Our PM has called for donations to the newly instituted PM-CARES Fund which has been formed on popular demand to help fight the novel coronavirus.

    PM-CARES Fund

    • The fund will be a public charitable trust under the name of ‘Prime Minister’s Citizen Assistance and Relief in Emergency Situations Fund’.
    • The PM is Chairman of this trust and members include the Defence Minister, Home Minister and Finance Minister.
    • Contributions to the fund will qualify as corporate social responsibility (CSR) spending that companies are mandated to make.
    • The Fund accepts micro-donations as well.

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  • Zoonotic Diseases: Medical Sciences Involved & Preventive Measures

    Indian Scientists’ Response to CoViD-19 (ISRC) Group

    Prelims Only | Science Tech | Mains Paper 3: Awareness in various sc and tech fields

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Indian Scientists’ Response to CoViD-19 (ISRC)

    Mains level: Not Much

    Several Indian scientists have come together to form a Google group to address some of the concerns that the COVID-19 outbreak has thrown up.

    Indian Scientists’ Response to CoViD-19 (ISRC)

    • It is a voluntary group of scientists who regularly discuss the rapidly evolving situation with its dire need for science communication.
    • With nearly 200 members, the group has scientists from institutions such as the NCBS, the IISc, the TIFR, the IITs, the IISERs and many others.
    • The group aims to study existing and available data to bring out analyses that will support the Central, State and local governments in carrying out their tasks.

    Self-assigned tasks

    • Several working groups have been formed by scientists.
    • They include one on hoax busting to address disinformation spreading with respect to the coronavirus and one on science popularization to develop material that explains concepts such as home quarantine.
    • Other groups work on resources in Indian languages, mathematical models and apps.

    Why such a group?

    • The scientific community has realized their social and democratic responsibility in the current situation, both in terms of analysing the situation and reaching out to the public.

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  • Zoonotic Diseases: Medical Sciences Involved & Preventive Measures

    Serological test for COVID-19

    Prelims Only | Science Tech | Mains Paper 3: Awareness in various sc and tech fields

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: COVID 19 diagnosis

    Mains level: Coronovirus outbreak and its mitigation

    The ICMR invited bids for an estimated 10 lakh antibody kits (for serological tests) for the diagnosis of COVID-19.

    What are serological tests?

    • Viral infections are mainly identified by two kinds of tests– genetic and serological.
    • Genetic tests can identify infections that are active but cannot be used to detect past infections.
    • To trace how infections like the novel coronavirus have spread so far, it is important to detect people who contracted the disease in the past and have recovered.
    • This is what serological tests seek to determine.

    How are the two different?

    • The genetic test is conducted on a swab collected from the back of the throat, a liquid sample from the lower respiratory tract, or a simple saliva sample.
    • For SARS-COV-2, the virus’s RNA is first converted into DNA.
    • By a process called polymerase chain reaction (PCR), DNA fragments in the sample are copied exponentially — one is copied into two, the two are copied into four, and so on.
    • Unlike genetic tests, which look for RNA in swab samples, serological tests work on antibodies in blood samples. Hence, they are also called ‘antibody tests’.

    How serological tests work?

    • Antibodies, or protective proteins produced by the immune system to neutralize pathogens such as bacteria and viruses, are present in one’s bloodstream for a considerable period of time after the infection has gone.
    • To disable a pathogen, the antibody latches to a unique protein molecule on pathogen’s surface, called an antigen.
    • Serological tests use antigen molecules to detect the presence of antibodies relevant to the infection.
    • Generally, a blood sample is placed in a test tube that is lined with antigens on the inside. If the relevant antibodies are present, they latch on to the antigens.
    • Such tests are relatively inexpensive, and can display results within a few minutes.

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  • Economic Indicators and Various Reports On It- GDP, FD, EODB, WIR etc

    What is Keqiang Index’?

    Prelims Only | Economics | Mains Paper 3: Effects Of Liberalization On The Economy, Changes In Industrial Policy and their effects on Industrial Growth

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Keqiang Index

    Mains level: NA

    China’s GDP numbers which are preferably represented by Keqiang Index has been recently seen in news amid coronavirus outbreak.

    Keqiang Index

    • Li Keqiang index or Keqiang index is an economic measurement index created by The Economist to measure China’s economy using three indicators, as reportedly preferred by Li Keqiang.
    • It uses three other indicators:
    1. the railway cargo volume,
    2. electricity consumption and
    3. loans disbursed by banks
    • Li Keqiang currently the Premier of the People’s Republic of China, suggest the index as better economic indicator than official numbers of GDP.

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  • Health Sector – UHC, National Health Policy, Family Planning, Health Insurance, etc.

    What is Hantavirus?

    Prelims Only | Science Tech | Mains Paper 3: Awareness in various sc and tech fields

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Hantavirus

    Mains level: Rise in zoonotic diseases and their possible causes

    China has reported the death of a person from Yunnan Province who tested positive for the Hantavirus.

    What is Hantavirus?

    • The Hantaviruses are a family of viruses spread mainly by rodents. It is contracted by humans from infected rodents.
    • Cases of the Hantavirus in humans occur mostly in rural areas where forests, fields and farms offer suitable habitat for infected rodents.
    • A person can get infected if he/she comes in contact with a rodent that carries the virus.
    • In the US and Canada, for instance, the Hantavirus carried by the deer mouse is responsible for the majority cases of the Hantavirus infection.
    • Like this, there are various other kinds of Hantaviruses that find hosts in rodents, like the white-footed mouse and the cotton rat among others that may lead to infections in humans if transmitted.

    Its origin

    • The Hantavirus is not novel and its first case dates back to 1993, according to the US Centre for Disease Control (CDC).
    • In the Americas, the family of viruses is known as ‘New World hantaviruses’.

    Symptoms

    • A person infected with the virus may show symptoms within the first to eighth week after they have been exposed to fresh urine, faeces or the saliva of infected rodents.
    • Symptoms may include fever, fatigue, muscle aches, headaches, chills and abdominal problems.
    • Four to ten after being infected, late symptoms of HPS may start to appear, which include coughing and shortness of breath.

    Mortality risk

    • It is the cause of Hantavirus pulmonary disease (HPS), a severe respiratory disease. The HPS can be fatal and has a mortality rate of 38 per cent.
    • It remains unclear whether human-to-human transmission of the virus is possible.
    • There have been no reports of human-to-human transmission of Hantavirus in the US.

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