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  • Roads, Highways, Cargo, Air-Cargo and Logistics infrastructure – Bharatmala, LEEP, SetuBharatam, etc.

    India’s first underwater transport tunnel spanning the Hooghly River

    Prelims Only | Economics | Mains Paper 3: Infrastructure: Energy, Ports, Roads, Airports, Railways Etc.

    tunnel

    Central idea: The East-West Metro corridor, the second line of Kolkata’s Metro network that is currently under construction, will connect Kolkata and Howrah, and one of its highlights is India’s first underwater transport tunnel spanning the Hooghly river.

    Hooghly River: Some facts

    Description
    Name Bhagirathi Hooghly River (Anglicized alternatively spelled Hoogli or Hugli)
    Source Close to Giria, north of Baharampur and Palashi, in Murshidabad
    Length 260 km
    Flows through West Bengal
    Endpoint Bay of Bengal
    Importance Lifeline for Kolkata, transportation route for goods and people, historical trade route, cultural and ecological resource
    Challenges Changing course, frequent floods, pollution from industrial effluents and sewage
    Additional Information A man-made canal called the Farakka Feeder Canal connects the Ganges to the Bhagirathi to bring the abundant waters of the Himalayan river to the narrow river that rises in West Bengal.

    The main course of the Ganges then flows into Bangladesh as the Padma.

    The Bhagirathi Hooghly River is also called the Ganga or the Kati-Ganga in the Puranas.

    About the East-West Corridor

    • The East-West Corridor is expected to significantly ease congestion in the city.
    • The line connects Kolkata’s IT hub of Salt Lake Sector V to the western suburb of Howrah.
    • The eastern part of the East-West line is operational while the western portion of the corridor is underground.
    • There are 12 stations on the entire route, including the country’s deepest, Howrah, at a depth of 33 meters.

    Key feature: Underwater Tunnel

    • The tunnels under the Hooghly River are 520 meters long and more than 30 meters below the river surface at its deepest point.
    • The trains will have an operational speed of 80 km/h and will cover the half-kilometre stretch under the Hooghly in about 45 seconds.
    • The underwater tunnels have an internal diameter of 5.55 meters and an external diameter of 6.1 meters.

     

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  • Wildlife Conservation Efforts

    Species in news: Olive Ridley Turtles

    Prelims Only | Enviro & Biodiversity | Mains Paper 3: Conservation, Environmental Pollution & Degradation, Eia

    olive

    Millions of baby Olive Ridley Turtles crawled towards the Bay of Bengal after emerging from eggshells along Odisha’s Rushikulyabeach in the Ganjam district.

    Olive Ridley Turtles

    Description
    Scientific name Lepidochelys olivacea
    Habitat Warm and tropical waters
    Found in Pacific and Indian Oceans
    Nesting sites Rushikulya rookery in Odisha
    Largest mass nesting site Coast of Odisha in India
    Conservation status Vulnerable in IUCN Red List
    Listed in Schedule 1 in Wildlife Protection Act, 1972

    Special feature: Mass nesting

    Notable behavior Arribadas
    Nesting habits Synchronized mass nesting and return to the same beach where they hatched
    Nest structure Conical nests about one and a half feet deep, dug with hind flippers
    Incubation period 45 to 60 days, influenced by temperature of the sand and atmosphere

     

     

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  • Mother and Child Health – Immunization Program, BPBB, PMJSY, PMMSY, etc.

    What is Garbh-Ini Program?

    Prelims Only | Science Tech | Mains Paper 3: Awareness in various sc and tech fields

    Central idea: The scientists working in the Garbh-Ini program have identified 19 single nucleotide polymorphisms (SNPs) or genetic markers that are associated with preterm or premature birth.

    What is Garbh-Ini?

    • It is an interdisciplinary research program in India that focuses on the advanced research of birth outcomes.
    • It is a collaborative initiative under the Department of Biotechnology.
    • It is led by DBT-Translational Health Science and Technology Institute (THSTI) in the NCR Biotech cluster, Faridabad, in collaboration with DBT-NIBMG, Kalyani, DBT-Regional Centre for Biotechnology (RCB), Gurugram Civil Hospital, and other organizations.
    • The program aims to use advanced technology to improve maternal and child health outcomes and address the high incidence of preterm births in India.

    What are Single Nucleotide Polymorphisms (SNPs)?

    • Genetic markers are specific sequences of DNA that can be used to identify an individual or a particular trait.
    • Single nucleotide polymorphisms (SNPs) are the most common type of genetic variation that occurs in the DNA sequence.
    • SNPs occur when a single nucleotide (A, C, T, or G) in the DNA sequence is altered.
    • These changes can occur in any region of the genome and can be used as genetic markers to identify specific traits or disease susceptibility.

    Significance of the Study

    • The study is significant as it identifies 19 SNPs or genetic markers that are associated with preterm or premature birth.
    • Out of these 19 SNPs, five were found to be associated with an increased risk of early preterm birth (birth before 33 weeks) and can be used to predict premature births.
    • This is the first study in South Asia to identify genetic markers associated with preterm births, and it has significant implications for improving maternal and child health outcomes in India.

     

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  • Gravitational Wave Observations

    LIGO-India: India’s Contribution to the Growth of Modern Astronomy

    op-ed snap | Science Tech | Mains Paper 3: Awareness in various sc and tech fields

    Central Idea

    The Union Cabinet approved the full budget for the LIGO-India mega-science project, which includes the construction, commissioning and joint scientific operation of a state-of-the-art, advanced Laser Interferometer Gravitational-Wave Observatory (LIGO) in India in collaboration with the NSF-funded LIGO Laboratory, USA, operated by Caltech and MIT.

    About LIGO-India

    • LIGO-India will be the fifth node of this international network of gravitational wave observatories, and possibly the last.
    • The instrument is so sensitive that it can easily get influenced by events like earthquakes, landslides, or even the movement of trucks, and produce a false reading.
    • That is why multiple observatories are needed to revalidate the signals.
    • India’s involvement in LIGO is crucial to demonstrating its intent and capability to pull-off complex science projects independently

    Facts for prelims: What is LIGO?

    What is it?

    Laser Interferometer Gravitational-Wave Observatory (LIGO)

     
    Purpose Detect and study gravitational waves
    Cause Ripples in spacetime caused by violent and energetic events in the universe
    Location Livingston, Louisiana and Hanford, Washington
    Detector Michelson interferometer
    Function Measure changes in length caused by passing gravitational waves

     
    Benefits Improving our understanding of the universe and its origins
    Discovery Detected gravitational waves for the first time in 2015

     
    Significance Confirmed a prediction made by Albert Einstein’s theory of general relativity

     
    Field Gravitational wave astronomy
    Discoveries Many exciting discoveries about the nature of the universe

     

     Significance of LIGO-India

    • Advancement in gravitational-wave astronomy and astrophysics: LIGO-India will significantly enhance global capabilities in the field of gravitational-wave astronomy and astrophysics. The project will enable an entirely new window to our universe and open up opportunities to study the cosmos in ways that were previously impossible.
    • Boosting research careers: LIGO-India will provide opportunities for Indian youth to pursue research careers in cutting-edge areas of science and technology, thereby supporting the growth of the Indian science industry and economy.
    • Development of cutting-edge technologies: LIGO-India will lead to the development of cutting-edge technologies such as lasers, optics, vacuum, quantum metrology and control-system technologies, which have great national relevance. The project will bring together researchers in fundamental and applied sciences from national research laboratories, IITs and IISERs to universities in partnership with the industry, and attract talent from the large pool of Indian researchers spread worldwide.
    • Galvanizing India’s industry: The project will galvanize India’s industry to enhance capability and capacity to engineer and manufacture complex components with precision to meet stringent scientific requirements, thereby enhancing the reputation of Indian industry.
    • Contributing to India’s mega-science ventures: LIGO-India is part of India’s mega-science ventures, which aim to lead or partner in very high-science goals through large-scale collaborative efforts requiring highly skilled human resources, significant fiscal capital and infrastructural investment, and close academia-industry partnerships. LIGO-India is expected to extend the legacy of successful world-class facilities such as the Giant Metrewave Radio Telescope (GMRT) near Pune and Himalayan Chandra Telescope (HCT) in Ladakh.

    Facts for prelims: Other Important science projects

    Mega-science Project

    Description
    Large Hadron Collider (LHC) Particle accelerator located in Switzerland, aims to study subatomic particles
    Indian-based Neutrino Observatory (INO) A proposed underground neutrino laboratory to be located in Tamil Nadu, India
    Facility for Antiproton & Ion Research (FAIR) A particle accelerator located in Germany, used for research in nuclear and particle physics
    Thirty Meter Telescope (TMT) A proposed astronomical observatory, with a mirror diameter of 30 meters, to be located in Hawaii
    Square Kilometre Array (SKA) A radio telescope that will be the largest and most sensitive in the world, to be located in Australia and South Africa
    Laser Interferometer Gravitational-Wave Observatory (LIGO) A facility designed to detect gravitational waves, with observatories located in the USA and India

    Way ahead: Mega-Science Projects and India’s S&T Policy

    • Mega-science projects like LIGO-India inculcate invaluable elements of work ethic in the scientific community.
    • The key is the ability to create a focused but adequately large well-knit collaborative ecosystem that remains open to growing by bringing in wider participation.
    • There is need for a culture within S&T communities to anticipate breakthroughs and appreciate new findings that may often deviate from the current comfort zone for policymakers to be receptive and for executing agencies to create robust mechanisms to assess, evaluate, and respond expeditiously to allow sufficient time to set up the enterprise.

    Conclusion

    The LIGO-India mega-science project is a significant milestone in India’s contribution to the growth of modern astronomy. The project will prompt Indian S&T in academia, national laboratories, and industries to leapfrog in a range of cutting-edge technologies. It reinforces the view that a healthy sprinkling of mega-science efforts in the overall S&T policy empowers and enriches the nation.

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  • Indian Air Force Updates

    India’s Fighter Jet Conundrum

    | Security Issues | Mains Paper 3: Various Security Forces, Agencies & Their Mandates

    india

    Central idea: The article discusses the challenges faced by the Indian Air Force (IAF) in modernizing its fighter jet fleet due to unending delays in procurement and limited resources.

    Why discuss this?

    • Against the sanctioned strength of 42 fighter squadrons, the IAF has only 31 squadrons today.
    • And this number is expected to remain the same or even decrease by 2029.
    • The IAF representative informed the Parliamentary standing committee that the shortfall may not be accomplished anytime soon.

    Indian Air Force (IAF): A quick backgrounder

    • The IAF was established in 1932, and it played an important role in India’s defence during World War II and later in the 1947-48 Kashmir War.
    • It underwent modernization in the 1960s and 70s with the induction of new aircraft and weapons systems.
    • Since then, the IAF has grown to become one of the largest air forces in the world, with a significant role to play in India’s defence and security.

    Evolution of the IAF

    Key Events
    Pre-Independence Phase – Small organization with only six officers and 19 airmen

    – Played a crucial role in World War II and the 1947-48 Kashmir War
    1947-1962 Phase – Expansion and modernization of the IAF

    – Acquisition of new aircraft and weapons systems
    1962-1980 Phase – Involvement in the 1965 and 1971 Indo-Pak wars

    – Modernization with the induction of new aircraft and missiles
    1980-Present Phase – Further modernization with the acquisition of new aircraft, missiles, and weapons systems

    – Focus on enhancing operational readiness

     

    Current Status of the IAF

    • Large workforce: The IAF has around 1,500 aircraft and 140,000 personnel, making it one of the largest air forces in the world.
    • Fleet details: The IAF has a sanctioned strength of 42 fighter squadrons, but the current strength stands at 31 squadrons.
    • Victorious wars: It has played an essential role in various conflicts, including the 1965 and 1971 Indo-Pak wars and the Kargil conflict in 1999.
    • HADR operation: It has also been involved in humanitarian assistance and disaster relief operations, such as the 2004 tsunami and the 2013 Uttarakhand floods.

    Challenges faced

    The IAF faces multiple challenges in the 21st century.

    • Decommissioning aircraft: By the end of the decade, many of the Jaguars, Mirage-2000s, and Mig-29s will begin going out, which is why the decision on Multi-Role Fighter Aircraft (MRFA) is essential to arrest this drawdown.
    • Arsenal shortages: The IAF faces a shortage of fighter aircraft, which is a significant concern given the current geopolitical environment.
    • Selective modernization: One of the critical issues is modernization, which includes the upgrading of its aircraft and weapons systems.
    • Diverse threat: The IAF also needs to ensure operational readiness to address the changing nature of warfare, which involves non-state actors, asymmetrical warfare, and cyber threats.
    • Logistic fallouts: Furthermore, the IAF needs to improve its logistics and infrastructure to support its operations effectively.
    • Maintenance challenges: There is a slow synergy with vendors for ‘long-term spares and repair contracts’.

    Opportunities for the IAF

    There are several opportunities for the IAF to enhance its capabilities in the modern era.

    • Modernization: The acquisition of new aircraft, weapons systems, and technologies can significantly enhance the IAF’s combat capabilities.
    • Joint cooperation: Additionally, the IAF can improve its international cooperation with other air forces to gain experience and enhance its interoperability.
    • UAV induction: The IAF can also explore the use of unmanned aerial vehicles (UAVs) for surveillance, reconnaissance, and combat roles.
    • Indigenization: The IAF is emphasizing the need for indigenization of its fighter jet production via LCA and Fifth Gen fighter aircraft program.

    Challenges in fleet modernisation

    • Procurement delay: The IAF faces significant challenges in modernizing its fleet due to delays in procurement and limited resources.
    • R&D, Infra bottlenecks: Implementing indigenization is a complex process that involves significant investment in research and development, infrastructure, and human capital.
    • Others: Other challenges include a lack of skilled labour, limited funding, and the need for technology transfer from foreign partners.

    Way forward

    • The IAF needs to prioritize the acquisition of MRFA, focus on increasing the availability rates of the Su-30, and invest in its own industry to achieve self-reliance in the long term.
    • Effective collaboration between industry, government, and the armed forces is crucial for the success of indigenization efforts in the defence sector.

     

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  • Minority Issues – SC, ST, Dalits, OBC, Reservations, etc.

    The Caste Census and Mandal Politics: Analysis

    op-ed snap | Polity | Mains Paper 2: Indian Constitution – historical underpinnings, evolution, features, amendments, significant provisions and basic structure

    Caste Census

    Central Idea

    • The demand for a caste-based census in India has once again brought Mandal politics to the forefront. Mandal politics has succeeded in capturing political power in large parts of India and has shifted the political discourse towards a universal acceptance of OBC reservations. However, the movement has weakened in recent years, and the demand for a caste census is seen as a way for Mandal parties to regain their hold in the public discourse.

    What do you understand by mean Mandal Politics?

    • Mandal politics refers to a political movement initiated by historically marginalized Other Backward Classes (OBCs) or Bahujan caste groups in India in the late 1980s and 1990s.
    • The movement sought to secure a greater share of political and economic power through reservation in the public sector for the OBCs who had been historically excluded from such opportunities.
    • The movement derived its name from the Mandal Commission, a committee appointed by the Indian government in 1979 to identify the socially and educationally backward classes of India and recommend measures for their advancement.
    • The Mandal Commission report in 1980 recommended that 27% of jobs in the public sector be reserved for OBCs, a recommendation that was later implemented by the Indian government in 1990.

    The outcomes of Mandal politics

    Positive outcomes:

    • Increased representation: One of the main positive outcomes of Mandal politics is the increased representation of OBCs and other marginalized groups in the political sphere. This has led to greater inclusivity and diversity in government and a more balanced distribution of power.
    • Reservation policies: Mandal politics has also led to the introduction and expansion of reservation policies, which aim to provide equal opportunities to marginalized groups in education and employment.
    • Recognition of social justice: Mandal politics has brought the issue of social justice to the forefront of political discourse and has highlighted the need for policies that address historic discrimination and disadvantage.

    Negative outcomes:

    • Caste-based politics: One of the negative outcomes of Mandal politics is the perpetuation of caste-based politics. This has led to the further entrenchment of caste divisions and has hindered the development of a more inclusive and egalitarian society.
    • Polarization and conflict: Mandal politics has also led to polarization and conflict between different caste groups, as each group seeks to secure its own interests.
    • Resentment and backlash: The policies introduced by Mandal politics have also led to resentment and backlash from certain upper-caste groups, who view the policies as discriminatory and unjust. This has sometimes led to violent protests and social unrest.

    What is Caste Census?

    • A caste census is basically the counting of people belonging to different castes in a particular marked area.
    • With this two-phase exercise, the Bihar government will try to get numbers of people belonging to SC, ST, and OBC communities and their financial status among other important things.
    • The exercise is termed ‘Jaati Aadharit Ganana’. People belonging to every religion and caste will be covered during the exercise.

    Arguments for caste census

    • Enumerating the marginalized: A caste census would actually bring to the particular the number of people who are at the margins, or who are deprived, or the kind of occupations they pursue, or the kind of hold that institutions like caste have on them. The caste census opens up to enumerating Dalits who are not Hindus, such as Dalit Christians and Muslims.
    • Data for Policymaking: This information is absolutely necessary for any democratic policymaking. The census will be able to answer real public policy questions and direct policies more effectively towards those who most need state assistance and affirmative action policies.
    • Judicial backing: The courts in India have often emphatically said that it is important to have adequate data with regard to the reservation.
    • Caste offers privilege: Caste is not only a source of disadvantage; it is also a very important source of privilege and advantage in our society.
    • Rids away caste rigidities: Counting of caste doesn’t necessarily perpetuate caste or the caste system. Myths of caste elitisms can be debunked through a caste census.

    Arguments against caste census

    • 50% breach of reservation cap: It is argued that a Socio-Economic Caste Census is the only way to make a case to breach the 50% cap on reservation and rationalize the reservation matrix in the country.
    • Caste within Caste: Given the differences in caste hierarchies across various regions of the country, a comparative reading along with generating a common hierarchy may be a challenge.
    • Caste over occupation linked predicaments: Caste linked deprivation or adversity may not be as common as occupation linked predicaments, which become easier to compare across states/regions.
    • Anonymity and bias: An intimate and personalised attribute like caste may have its differential exposition between urban and rural residents. Urban residents’ need for anonymity can always bias the reporting on caste.
    • Identity crisis: Recognition and adherence to caste identity is to a large extent shaped by progressive ideals, cosmopolitanism and education, which has its own regional divide in the country between the north and the south.
    • Hurdle to casteless society: The idea of a national caste census is abhorrent when the stated policy is to strive for a casteless society.

    The Impact of a Caste Census: Analysis In brief

    Positive impact

    • Accurate data: A caste census can provide accurate data on the caste demographics of India, which is necessary for effective policy-making and affirmative action programs.
    • Better targeting of government policies: The data from a caste census can help the government target policies and programs more effectively towards the marginalized and disadvantaged sections of society.
    • Improved representation: A caste census can help improve representation of underrepresented castes in government bodies and institutions.
    • Empowerment of marginalized communities: A caste census can help empower marginalized communities by giving them a voice and recognition in the political and social systems.

    Negative impact

    • Polarization: A caste census can lead to polarization and tensions between different castes, especially if the data is used to allocate resources or benefits based on caste.
    • Stigma and discrimination: There is a risk that the caste census data can be used to further stigmatize and discriminate against marginalized communities.
    • Misuse of data: The data from a caste census can be misused by politicians and other groups to further their own agendas, leading to potential conflicts and social unrest.
    • Privacy concerns: Some people may be hesitant to disclose their caste, leading to concerns about privacy and data protection.

    Conclusion

    • The caste census is seen as a way for Mandal parties to regain their hold in the public discourse and direct policies more effectively towards those who most need state assistance and affirmative action policies. However, the demand for a caste census is a double-edged sword that may create conflicts and shift the discourse from historical injustices to distribution. The Mandal movement faces challenges but remains relevant in the ongoing struggle for social justice.

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  • Tuberculosis Elimination Strategy

    Tuberculosis (TB) Should No Longer Exists in the 21st Century: India can lead the way

    op-ed snap | Governance | Mains Paper 2: Health & Education

    TB

    Central Idea

    • At the One World TB Summit in Varanasi, Uttar Pradesh on March 24, 2023, Prime Minister Narendra Modi called for a fresh approach to the global tuberculosis (TB) elimination response, with innovation and research being central drivers of change. This is a critical step as India and the world look to redefine their TB elimination response. India’s recent progress in TB control efforts and COVID-19 response provides a good reflection point, which offers lessons to address the challenges faced in the fight against TB.

    India’s Progress in TB Control Efforts

    • Expanded reach and improved detection measures: India’s National TB Elimination Programme has introduced several measures to find, notify, and treat TB cases, resulting in expanded reach and improved detection measures. As a result, the number of TB case notifications has significantly increased, rising from 15.6 lakh in 2014 to over 24 lakh in 2022.
    • Innovative approaches: India has adopted innovative approaches to TB management, including engagement with the private sector, launch of social support provisions, and introduction of diagnostic tools and new drug regimens. These measures have improved TB management in the country.
    • Increased investment in health research and development: India has recognized the importance of investing in health research and development, especially in recent years. The Mission COVID Suraksha programme to develop vaccines was a good example of a public-private partnership, with clear goals and outcomes. The country has also established centres of excellence, which will facilitate collaboration between Indian Council of Medical Research laboratories and the private sector.
    • Expansion of diagnostic tools: India has been working on expanding access to diagnostic tools for TB. Innovations such as nasal and tongue swab-based tests for TB can be a game changer by reducing diagnostic delays, and handheld digital x-ray machines with artificial intelligence-based software can now be taken to villages and urban settlements to screen large numbers of high-risk individuals.
    • Introduction of new therapeutic molecules: India has been investing in the development and introduction of new therapeutic molecules for TB treatment. Shorter, safer, and more effective regimens, such as the 1HP regimen for latent TB infections, the four-month regimen (HPZM) for drug-susceptible TB, and the six-month regimen (BPaL/M) for drug-resistant TB, have been developed.

    Why there is a Need for Disruptive Approaches and New Tools in TB elimination response?

    • Lack of widespread awareness: Despite the progress made by India’s National TB Elimination Programme, there is still a lack of widespread awareness about the disease, which has led to delayed diagnosis and treatment.
    • Access to quality care: Many people with TB in India and other developing countries do not have access to quality care, which has led to high rates of morbidity and mortality.
    • Limited diagnostic tools: There is a need to expand access to diagnostic tools for TB, especially in rural and remote areas.
    • Drug-resistant TB: The emergence of drug-resistant TB has made treatment more difficult, requiring the development of new therapeutic molecules and regimens.
    • Need for innovative approaches: Innovative approaches are needed to change the way TB is prevented, diagnosed, and treated.
    • Rapidly evolving technology: Advances in technology, such as point-of-care tests, artificial intelligence-based software, and handheld digital x-ray machines, have made it possible to develop new tools to combat TB.
    • For example: Innovative technologies such as handheld digital x-ray machines with artificial intelligence-based software and nasal and tongue swab-based tests for TB can reduce diagnostic delays and provide rapid, low-cost diagnostics. Similarly, newer and more effective regimens and repurposed existing drugs for TB can play a crucial role in the long run.

    Importance of Prioritizing TB Vaccine Trials

    • Vaccines are key to ending the TB epidemic: Vaccines are one of the most effective ways to prevent infectious diseases. For TB, a vaccine would be a critical tool for ending the epidemic, especially for those who are at the highest risk of developing and spreading TB.
    • BCG vaccine is not effective for all: The current TB vaccine, Bacille Calmette-Guérin (BCG), is not effective for everyone, especially adolescents and adults who are at the highest risk of developing and spreading TB. Therefore, new and effective vaccines are needed to provide adequate protection.
    • Multiple TB vaccine candidates in the pipeline: There are currently over 15 TB vaccine candidates in the pipeline, which have shown promise in pre-clinical and clinical trials. Prioritizing these clinical trials will help identify the most effective vaccine candidates for various community settings and different target groups.
    • Cost-effectiveness: Vaccines are a cost-effective way to prevent diseases, and a TB vaccine would be no different. Investing in TB vaccine trials and development would save resources in the long run by reducing the burden of TB on health systems and economies.
    • Global impact: TB is a global public health issue, affecting millions of people worldwide. The development of a new TB vaccine would have a significant impact not only in India but also in other high-burden countries.

    Facts for prelims: Types of vaccine technologies

    Vaccine Technology

    		 Explanation

    Examples
    Inactivated or killed vaccines Use viruses or bacteria that have been inactivated or killed so that they can no longer cause disease Inactivated polio vaccine, hepatitis A vaccine
    Live attenuated vaccines Use viruses or bacteria that have been weakened so that they can’t cause disease in healthy people Measles, mumps, and rubella (MMR) vaccine, yellow fever vaccine
    Protein subunit vaccines Use pieces of the virus or bacteria, such as proteins or sugar molecules, to stimulate an immune response Human papillomavirus (HPV) vaccine, pertussis (whooping cough) vaccine
    Nucleic acid vaccines Use genetic material from the virus or bacteria, such as DNA or RNA, to stimulate the immune system COVID-19 mRNA vaccines from Pfizer-BioNTech and Moderna
    Viral vector vaccines Use harmless viruses, such as adenoviruses, to deliver genetic material from the target virus or bacteria into the body to stimulate an immune response Johnson & Johnson COVID-19 vaccine, Ebola vaccine developed by Merck

    How Testing and Diagnosis of TB can be improved?

    • Increased access to diagnostic tools: There is a need to increase access to diagnostic tools for TB, especially in rural and remote areas. Innovative approaches such as point-of-care tests (POCTs), including home-based tests, can provide decentralized, rapid, and low-cost diagnostics to provide results within minutes.
    • Introduction of new diagnostic tools: New innovations such as nasal and tongue swab-based tests for TB can be a game changer by reducing diagnostic delays. Further, handheld digital x-ray machines (with artificial intelligence-based software) can now be taken to villages and urban settlements to screen large numbers of high-risk individuals, safely and conveniently.
    • Strengthening the laboratory network: It is essential to strengthen the laboratory network in India to ensure quality diagnostics, especially in the private sector. Accreditation of private laboratories for TB diagnosis and linking them with the public sector is essential.
    • Integration with other healthcare services: TB testing and diagnosis need to be integrated with other healthcare services to improve access and reduce stigma. For example, TB screening can be done in conjunction with diabetes or HIV screening.
    • Empowering patients: Empowering patients with knowledge about TB symptoms and diagnostic tests can help increase awareness and improve early diagnosis. TB awareness campaigns can also help reduce stigma associated with the disease.
    • Collaboration between public and private sectors: Collaboration between the public and private sectors can improve access to diagnostic tools and reduce the time required for TB testing and diagnosis. The private sector can be leveraged to provide affordable and quality TB diagnostics and treatment.

    Need for Appropriate Policy Frameworks

    • Smoothening the rollout of proven tools: Creating regulatory and policy frameworks can smoothen the rollout of proven tools to reach people with as little delay as possible. This requires greater collaboration between policymakers, scientists, product developers, and clinical researchers across the country and even across regions.
    • Harmonization of standards and regulatory processes: Harmonization of standards and regulatory processes between countries can enable mutual recognition of evidence-based standards and licenses and save critical time towards rollout.
    • Addressing the regulatory challenges: Appropriate policy frameworks can address the regulatory challenges of introducing new tools and approaches. This can help reduce the time and cost of clinical trials and shorten the time to market for new tools and products.
    • Encouraging innovation: Policy frameworks that incentivize innovation can encourage the private sector to invest in TB research and development. This can lead to the development of new and effective tools for TB prevention, diagnosis, and treatment.
    • Supporting public-private partnerships: Appropriate policy frameworks can support public-private partnerships that can bring together the strengths of both sectors to develop and scale up innovative solutions for TB control.

    Conclusion

    • India’s scientific ingenuity during the COVID-19 pandemic has cemented its position as pioneers in innovation in the life sciences. India must use its G-20 presidency to build a global health architecture that creates equitable access for all. India must use this opportunity to call for the collaborative development of transformational tools and approaches that cater to not only India’s needs but also those of the under-represented but disproportionately affected developing world. TB should no longer be the leading infectious disease killer globally in the 21st century, and India can lead the way.

    Mains Question

    Q. At the One World TB Summit held at in Varanasi recently, Prime Minister Narendra Modi called for a fresh approach to the global tuberculosis (TB) elimination response. In this light discuss India’s Progress in TB Control Efforts and the need for disruptive approaches and new tools in TB elimination response.

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  • Climate Change Impact on India and World – International Reports, Key Observations, etc.

    Oceans absorb 90% of human-induced planet warming: Study

    Prelims Only | Enviro & Biodiversity | Mains Paper 1: Important Geophysical Phenomena

    ocean

    The study published in the journal Earth System Science Data estimates that almost 90% of the warming that has occurred in the last 50 years has been absorbed by the ocean, with the remaining heat absorbed by the land, cryosphere and atmosphere.

    Earth’s energy balance: A quick recap

    ocean

    • It is the balance between the amount of energy that Earth receives from the Sun and the amount of energy that Earth radiates back into space.
    • It is also known as the radiation budget.
    • The energy from the Sun that Earth receives is mainly in the form of visible light and ultraviolet radiation.
    • This energy is absorbed by the Earth’s surface and atmosphere, which then radiate it back into space in the form of infrared radiation.
    • The balance between incoming and outgoing radiation is crucial for maintaining the Earth’s temperature and climate.
    • Any imbalance between the two can lead to global warming and climate change.
    Description
    Total incoming solar radiation Approximately 342 W/m² reaches Earth’s atmosphere
    Albedo About 30% of incoming solar radiation is reflected back to space
    Greenhouse effect Remaining 70% of incoming solar radiation is absorbed by Earth’s surface and atmosphere, creating the greenhouse effect
    Atmospheric heat Atmosphere contains only 0.001% of Earth’s heat energy, but is crucial in regulating heat budget

     

    Key highlights of the Study: Heat Accumulation

    heat

    • The study estimates that approximately 381 zettajoules (ZJ) of heat accumulated on the planet from 1971-2020 due to anthropogenic emissions.
    • This roughly equals a heating rate of approximately 0.48 watts per square metre (Earth Energy Imbalance or EEI). EEI is the difference between incoming and outgoing solar radiation.
    • According to the study, about 89% of the accumulated heat is stored in the ocean, 6% on land, a percent in the atmosphere, and about 4% available for melting the cryosphere.

    Implications

    (1) Land Heat Accumulation

    • Heat accumulated on land drives up ground surface temperatures, which may increase soil respiration, releasing carbon dioxide in the process.
    • Higher soil respiration will likely decrease soil water, depending on climatic and meteorological conditions and factors.

    (2) Inland Water Bodies and Permafrost Thawing

    • Heat storage within inland water bodies has increased to roughly 0.2 ZJ since 1960. For permafrost thawing, it was about 2 ZJ.
    • The accumulation of heat in inland water increases lake water temperatures, making conditions ripe for algal blooms.
    • Permafrost heat content could inject methane and carbon dioxide into the atmosphere, the researchers warned.

    (3) Ocean and Troposphere heating

    • The upper ocean (0-300 and 0-700 meters depth) has taken up a major fraction of heat, according to the new estimates.
    • During 2006-2020, ocean warming rates for the 0-2,000 meters depth reached record rates of roughly 1.03 watts per square meter.
    • The troposphere is also warming up due to increased heat accumulation.

    (4) Cryosphere heating

    • The cryosphere – the frozen water part of the Earth system – gained roughly 14 ZJ of heat from 1971-2020.
    • Half of the uptake triggered the melting of grounded ice, while the remaining half is linked to the melting of floating ice.
    • The Antarctic Ice Sheet contributed about 33% to the total cryosphere heat gain, while Arctic sea ice stood second, having contributed 26%.

     

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  • International Space Agencies – Missions and Discoveries

    NASA develops Exobiology Extant Life Surveyor (EELS)

    Prelims Only | Science Tech | Mains Paper 3: Awareness in various sc and tech fields

    eels

    NASA is developing a snake-like robot- Exobiology Extant Life Surveyor (EELS), which it says can boost space exploration through its diverse adaptability to various terrains.

    Exobiology Extant Life Surveyor (EELS)

    Details
    Purpose Designed to explore internal and enclosed dynamic terrain structures to assess evidence for life.
    Focus To explore ocean-world-inspired terrain, and besides Enceladus, it can explore Martian polar caps and descending crevasses in Earth’s ice sheets.
    Enceladus and EELS system Enceladus is a small and icy body, and the Cassini spacecraft dubbed it to be one of the most scientifically interesting destinations in the solar system.
    Scientific investigations Work is underway to identify high-priority and high-impact scientific investigations to show the capabilities of the snake-like robot.

     

    Features of EELS Robot

    Details
    Propulsion and gripping mechanism EELS robot has an actuation and propulsion mechanism, driven by power and communication electronics.

    It uses a rotating propulsion unit that acts as tracks, while the gripping mechanism and propeller unit help it to access a plume vent exit.
    Adaptability The robot’s adaptability to various terrains and its unique features make it capable of exploring areas that were once inaccessible.
    Enceladus Geyser-like jets spew water vapor and ice particles from an underground ocean beneath Enceladus’s icy crust, making it a promising lead for NASA in its search for life.

     

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  • Indian Air Force Updates

    Exercise INIOCHOS-23

    Prelims Only | Security Issues | Mains Paper 3: Various Security Forces, Agencies & Their Mandates

    iniochos

    The Indian Air Force (IAF) will be participating in a multi-national air exercise called Exercise INIOCHOS-23, which will be hosted by the Greece Air Force.

    Ex. INIOCHOS-23

    • Exercise INIOCHOS-23 will be conducted at the Andravida Air Base in Greece.
    • The IAF will be participating with four Su-30 MKI and two C-17 aircraft.
    • The objective of the exercise is to enhance international cooperation, synergy, and interoperability among the participating Air Forces, as stated by the IAF in a statement.

    Strategic significance

    • The exercise will be conducted in a realistic combat scenario involving multiple types of air and surface assets
    • This will provide valuable insight into each other’s best practices and enable the participating contingents to interact professionally.

     

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