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Type: Prelims Only

  • Digital India Initiatives

    [pib] E-Sanjeevani Telemedicine Service

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: E-Sanjeevani

    Mains level: Telemedicine and its effectiveness

    In a landmark achievement, eSanjeevani, Health Ministry’s national telemedicine initiative today completed 9 lakh consultations.

    Although telemedicine brings with it many benefits, there are some downsides to it as well. Discuss.

    What is E-Sanjeevani?

    • Ministry of Health & Family Welfare has launched two variants of eSanjeevani namely – doctor to doctor (eSanjeevani AB-HWC) in the hub and spoke model and patient to doctor (eSanjeevaniOPD).
    • E-Sanjeevani OPD (out-patient department) is a telemedicine variant for the public to seek health services remotely; it was rolled out on 13th of April 2020 during the first lockdown in the country.
    • It enables virtual meetings between the patients and doctors & specialists from geographically dispersed locations, through video conferencing that occurs in real-time.
    • At the end of these remote consultations, eSanjeevani generates electronic prescriptions which can be used for sourcing medicines.
    • Andhra Pradesh was the first state to roll out eSanjeevani AB-HWC services in November 2019.

    Benefits of telemedicine

    Telemedicine benefits patients in the following ways:

    • Transportation: Patients can avoid spending gas money or wasting time in traffic with video consultations.
    • No missing work: Today, individuals can schedule a consultation during a work break or even after work hours.
    • Childcare/Eldercare Challenges: Those who struggle to find care options can use telemedicine solutions.
  • Minimum Support Prices for Agricultural Produce

    1.5x Formula for crops MSP calculation

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: MSP calculation

    Mains level: Fixation of MSP and its legal backing

    Talks between farmer unions and the government failed to reach a resolution. The main bone of contention in these talks is the Minimum Support Price (MSP) for crops, which farmers fear the new laws will do away.

    Try this:

    Q.There is also a point of view that agriculture produce market committees (APMCs) set up under the state acts have not only impeded the development of agriculture but also have been the cause of food inflation in India. Critically examine. (CSM 2014)

    What is MSP?

    • The MSP assures the farmers of a fixed price for their crops, well above their production costs.
    • MSP, by contrast, is devoid of any legal backing. Access to it, unlike subsidised grains through the PDS, isn’t an entitlement for farmers.
    • They cannot demand it as a matter of right. It is only a government policy that is part of administrative decision-making.
    • The Centre currently fixes MSPs for 23 farm commodities based on the Commission for Agricultural Costs and Prices (CACP) recommendations.

    Why in news yet again?

    • The Union Budget for 2018-19 had announced that MSP would be kept at levels of one and half times of the cost of production.
    • This year the govt. has increased the MSP for all mandated Kharif, Rabi and other commercial crops with a return of at least 50 per cent of the cost of production for the agricultural year 2018-19 and 2019-20.
    • This is the ambiguity from where this 1.5 times formula arrived at.

    How did the government fix the MSPs of crops before every planting season?

    • The CACP considered various factors while recommending the MSP for a commodity, including the cost of cultivation.
    • It also takes into account the supply and demand situation for the commodity; market price trends (domestic and global) and parity vis-à-vis other crops; and implications for consumers (inflation), environment (soil and water use) and terms of trade between agriculture and non-agriculture sectors.

    What changed with the 2018 budget?

    • The Budget for 2018-19 announced that MSPs would henceforth be fixed at 1.5 times of the production costs for crops as a “pre-determined principle”.
    • Simply put, the CACP’s job now was only to estimate production costs for a season and recommend the MSPs by applying the 1.5-times formula.

    How was this production cost arrived at?

    • The CACP projects three kinds of production cost for every crop, both at the state and all-India average levels.
    • ‘A2’ covers all paid-out costs directly incurred by the farmer — in cash and kind — on seeds, fertilisers, pesticides, hired labour, leased-in land, fuel, irrigation, etc.
    • ‘A2+FL’ includes A2 plus an imputed value of unpaid family labour.
    • ‘C2’ is a more comprehensive cost that factors in rentals and interest forgone on owned land and fixed capital assets, on top of A2+FL.

    Now try this PYQ:

    Q.The economic cost of food grains to the Food Corporation of India is Minimum Support Price and bonus (if any) paid to the farmers plus:

    (a) Transportation cost only

    (b) Interest cost only

    (c) Procurement incidentals and distribution cost

    (d) Procurement incidentals and charges for godowns

    Which production costs were taken in fixing the MSPs?

    • In 2018, then FM Arun Jaitley’s did not specify the cost on which the 1.5-times formula was to be computed.
    • But the CACP’s ‘Price Policy for Kharif Crops: The Marketing Season 2018-19’ report stated that its MSP recommendation was based on 1.5 times the A2+FL costs.

    What are the farmer’s demands?

    • Farm activists, however, had said that the 1.5-times MSP formula should have been applied on the C2 costs.
    • CACP considers A2+FL and C2 costs, both while recommending MSP. It reckons only A2+FL cost for return.
    • However, C2 costs are used by CACP primarily as benchmark reference costs (opportunity costs) to see if the MSPs recommended by them at least cover these costs in some of the major producing States.
  • Pharma Sector – Drug Pricing, NPPA, FDC, Generics, etc.

    What is the Emergency Use Authorization (EUA) for Drugmakers?

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Vaccine for COVID

    Mains level: Universalization of vaccines and associated challenges in India

    The US drugmaker Moderna said it was applying for emergency use authorisation for its vaccine in India.

    Practice question for Mains:

    Q. What is Vaccine Nationalism? Discuss various ethical issues involved and its impact on vulnerable populations across the globe.

    Emergency Use Authorisation (EUA)

    • Vaccines and medicines, and even diagnostic tests and medical devices, require the approval of a regulatory authority before they can be administered.
    • In India, the regulatory authority is the Central Drugs Standard Control Organisation (CDSCO).
    • The approval is granted after an assessment of their safety and effectiveness, based on data from trials. In fact, approval from the regulator is required at every stage of these trials.
    • This is a long process, designed to ensure that medicine or vaccine is absolutely safe and effective.
    • The fastest approval for any vaccine until now — the mumps vaccine in the 1960s — took about four-and-a-half years after it was developed.

    Exceptions for emergency

    • In emergency situations, like the current one, regulatory authorities around the world have developed mechanisms to grant interim approvals.
    • However, there should sufficient evidence to suggest a medical product is safe and effective.
    • Final approval is granted only after completion of the trials and analysis of full data; until then, EUA allows the medicine or the vaccine to be used on the public.

    What is the process of getting a EUA in India?

    • India’s drug regulations do not have provisions for a EUA, and the process for receiving one is not clearly defined or consistent.
    • Despite this, CDSCO has been granting emergency or restricted emergency approvals to Covid-19 drugs during this pandemic — for remdesivir and favipiravir in June, and itolizumab in July.

    Associated risks

    • The public has to be informed that a product has only been granted a EUA and not full approval.
    • In the case of a Covid-19 vaccine, for example, people have to be informed about the known and potential benefits and risks.

    Not a compulsion

    • There has been an ongoing debate over whether people have the option of refusing to take the vaccine.
    • Incidentally, no country has made vaccination compulsory for its people.
    • Initially, all vaccines are likely to be deployed on emergency use authorizations only. Final approval from may take several months, or years.
  • International Space Agencies – Missions and Discoveries

    Japan’s Hayabusa2 Probe

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Hayabusa2 Probe

    Mains level: Not Much

    A Japanese spacecraft is nearing Earth after a yearlong journey home from a distant asteroid with soil samples. It is set to land in Australia.

    Try this PYQ:

    Which of the following is/are cited by the scientists as evidence/evidence for the continued expansion of the universe?

    1. Detection of microwaves in space
    2. Observation of redshirt phenomenon in space
    3. Movement of asteroids in space
    4. Occurrence of supernova explosions in space

    Codes:

    (a) 1 and 2 only

    (b) 2 only

    (c) 1, 3 and 4

    (d) None of the above can be cited as evidence.

    Hayabusa2 Probe

    • Hayabusa2is an asteroid sample-return mission operated by the Japanese space agency, JAXA.
    • It follows on from the Hayabusa mission which returned asteroid samples in 2010.
    • It was launched on 3 December 2014 and rendezvoused with near-Earth asteroid 162173 Ryugu on 27 June 2018.
    • It surveyed the asteroid for a year and a half and took samples. It left the asteroid in November 2019.
    • It carries multiple science payloads for remote sensing, sampling, and four small rovers that investigated the asteroid surface to inform the environmental and geological context of the samples collected.
  • Horticulture, Floriculture, Commercial crops, Bamboo Production – MIDH, NFSM-CC, etc.

    Cultivation of ‘Wild’ Arunachal Kiwi

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Arunachal Kiwi

    Mains level: Organic farming in India

    Recently, the ‘Wild’ Arunachal Kiwi has received organic certification by the Mission Organic Value Chain Development for the North East Region.

    Try this PYQ:

    Q.Among the agricultural commodities imported by India, which one of the following accounts for the highest imports in terms of value in the last five years?

    (a) Spices

    (b) Fresh fruits

    (c) Pulses

    (d) Vegetable oils

    Arunachal Kiwi

    • The kiwifruit (Actinidia deliciosa Chev.) is a deciduous fruiting vine native to Yangtze River valley of south and central China.
    • In Arunachal Pradesh, a domesticated variety of kiwi was introduced as a commercial fruit only in 2000.
    • The Ziro Valley specifically located at 1,500-2,000 metres above sea level is the most ideal for kiwi.
    • It is also called “China’s miracle fruit” and “Horticulture wonder of New Zealand”.

    Benefits of certification

    • Certification helps producers and handlers; they receive premium prices for the products and have access to fast-growing, local, regional and international markets.

    Organic certification in India

    • An agricultural practise/product is considered organic when there are no chemical fertilizers or pesticides involved in its cultivation process.
    • Such certifications in India can be obtained after a strict scientific assessment done by the regulatory body, Agricultural and Processed Food Products Export Development Authority (APEDA).
  • Innovations in Biotechnology and Medical Sciences

    Zebrafish and its heart regeneration capacity

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Zebrafish

    Mains level: Not Much

    Indian scientists have used the Zebrafish model and identified its genes that can promote heart regeneration.

    Try this PYQ:

    Q.With reference to India’s Biodiversity, Ceylon frogmouth, Coppersmith Barbet, Gray-chinned minivet and White-throated redstart are-

    (a) Birds

    (b) Primates

    (c) Reptiles

    (d) Amphibians

    Zebrafish

    • Zebrafish is a small (2-3 cm long) freshwater fish found in the tropical and subtropical regions.
    • The fish is native to South Asia’s Indo-Gangetic plains, where they are mostly found in the paddy fields and even in stagnant water and streams.
    • The fish become adults at three months and survive 2-3 years in a laboratory condition.
    • Its unique characteristics lie in its transparency during its embryonic stages, allowing observing all organs, including beating heart and blood circulation.

    Ability to heal their heart

    • The ability of Zebrafish to heal their heart after injury makes them an attractive model to investigate mechanisms governing the regenerative process.
    • Researchers worldwide are actively working to understand the mechanism behind the heart regeneration in Zebrafish for the last two decades.
    • Years of efforts have helped them identify the cellular communication network factor 2a (ccn2a), a gene that can promote heart regeneration by enhancing cardiomyocyte proliferation.
    • They have also observed that this gene resolves the transient collagenous fibrotic scar resulting in faster regeneration.

    Significance for humans

    • Cardiovascular diseases are the number 1 cause of deaths globally, taking an estimated 17.9 million lives each year, according to the World Health Organisation.
    • Humans cannot regenerate their hearts upon myocardial damage and a person who suffered a heart attack cannot functionally heal the damaged heart muscle, resulting in reduced pumping efficiency.
    • While on the other hand, this unique fish has the full potential to regenerate its heart and restore its function after injury.
    • Till now, there is no treatment available to restore the damaged heart function in humans. Hence scientists have sought to decode the heart regeneration processes using this model animal.
  • Historical and Archaeological Findings in News

    In new: Annapurna Idol

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Annapurna idol

    Mains level: Not Much

    PM has announced that an ancient idol of the goddess Annapurna, stolen from India about a century ago, is being brought back from Canada.

    Must revise: Gandhara and Mathura school of Art

    [Static Revision] Chapter 6 | Post Mauryan Period (200BC to 300AD)

    Annapurna Idol

    • Annapurna, also spelt Annapoorna, is the goddess of food.
    • This 18th-century idol, carved in the Benares was stolen from a temple of Varanasi and smuggled out around 100 years ago somewhere around 1913.
    • Now is part of the University of Regina, Canada’s collection at the MacKenzie Art Gallery.
    • The idol holds a bowl of kheer in one hand and a spoon in the other.
  • Coronavirus – Health and Governance Issues

    RT-LAMP: a new technology for detecting COVID-19

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: RT-PCR, LAMP

    Mains level: COVID testing issues

    Indian Council of Medical Research has recently validated the LAMP technology for COVID-19 testing.

    What is RT-LAMP?

    • RT-LAMP stands for Reverse Transcriptase loop-mediated isothermal amplification) technology.
    • Agappe Diagnostics has recently developed the technology indigenously, and their kit has been validated and approved by the ICMR for marketing.
    • It is named LUME Screen nCoV.

    How does it work?

    • RT-LAMP technology is a one-step nucleic acid amplification method to multiply specific sequences of RNA of the coronavirus.
    • The RNA is first made into cDNA (copy DNA) by the usual reverse transcription. Then, the DNA is amplified by the LAMP technique.

    Current method

    • The current method diagnosis is the real time reverse transcription polymerase chain reaction (RT-PCR) test which detects the presence of viral nucleic acids in nasopharyngeal swab samples.
    • But it has certain shortcomings.
    • The test requires complex and costly equipment. It requires extensive training for potential users.

    Benefits of LAMP over RT-PCR

    • The LAMP technology is superior to the PCR technology–based COVID-19 kits where specificity is around 95% only.
    • As the specificity and sensitivity of the test is about 95%, there is a possibility of false negative results.
    • The turnaround time is about 10 hours, so that the result will be available only by the next day.
    • In remote places, the turnaround time further increases depending on the distance the samples need to travel.
    • In short, the RT-PCR does not have the capacity to keep pace with the increasing demand.
    • The LAMP technology does not need laborious preparation as in the case of RT-PCR. LAMP is cost effective and does not need complex expensive equipment.

     

  • Police Reforms – SC directives, NPC, other committees reports

    Brain Electrical Oscillation Signature Profiling (BEOSP)

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: BEOSP

    Mains level: Use of technolgy in crime investigations

    A brain electrical oscillation signature profiling (BEOSP) test will be conducted on the convicts of the alleged rape and murder in Hathras, Uttar Pradesh.

    Note: According to Article 20(3) of the Indian constitution, no person accused of any offence shall be compelled to be a witness against himself. The privilege against self-incrimination is a fundamental canon of common criminal law jurisprudence.

    What is the BEOSP test?

    • BEOSP also known as brain fingerprinting is a neuro-psychological method of interrogation in which the accuser’s participation in the crime is investigated by studying their brain’s response.
    • The BEOSP test is carried out via a process known as an electroencephalogram, conducted to study the electrical behaviour of the human brain.
    • Under this test, the consent of the accused is first taken and they are then made to wear caps with dozens of electrodes attached to them.
    • The accused are then shown visuals or played audio clips related to the crime to check if there is any triggering of neurons in their brains which then generate brainwaves.
    • The test results are then studied to determine the participation of the accused in a crime.

    What differentiates a BEOSP test from a polygraph or a lie detector?

    • The BEOSP procedure does not involve a question-answer session with the accused and is rather a neuro psychological study of their brain.
    • In a polygraph test, the accused person’s physiological indicators are taken into account which includes blood pressure, pulse rate, respiration and skin conductivity.
    • While a person might be able to control their pulse rate and BP even in times of distress, a BEOSP test

    Can these tests be admitted as evidence?

    • Not as a standalone, a/c to the 2010 Supreme Court judgment in the Selvi v. State of Karnataka case.
    • The bench observed that narco analysis, polygraph and brain mapping tests cannot be forced upon any individual without their consent and the test results cannot be admitted solely as evidence.
    • However, any information or material discovered during the tests can be made part of the evidence, observed the bench.
  • Indian Missile Program Updates

    BrahMos Missiles and their significance for Armed Forces

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Brahmos Missiles

    Mains level: India's missile arsenal

    India’s Armed forces are conducting back-to-back tests of various versions of BrahMos missile.

    Take a quick look at India’s missile arsenal:

    [Prelims Spotlight] Missiles

    The BrahMos Missiles

    • A combination of the names of Brahmaputra and Moskva rivers, BrahMos missiles are designed, developed and produced by BrahMos Aerospace, a joint venture company set up by DRDO and Mashinostroyenia of Russia.
    • It is a two-stage missile with a solid propellant booster as the first stage and liquid ramjet as the second stage.
    • The cruise missiles like BrahMos are a type of systems known as the ‘standoff range weapons’ which are fired from a range sufficient to allow the attacker to evade defensive fire from the adversary.
    • These weapons are in the arsenal of most major militaries in the world.
    • The versions of the BrahMos that are being tested have an extended range of around 400 km, as compared to its initial range of 290 km, with more versions of higher ranges currently under development.

    Various versions

    • Various versions of the BrahMos, including those which can be fired from land, warships, submarines and Sukhoi-30 fighter jets have already been developed and successfully tested in the past.
    • The earliest versions of the ship launched BrahMos and land-based system are in service of the Indian Navy and the Indian Army since 2005 and 2007 respectively.