💥UPSC 2026, 2027, 2028 UAP Mentorship (March Batch) + Access XFactor Notes & Microthemes PDF

Type: Prelims Only

  • Health Sector – UHC, National Health Policy, Family Planning, Health Insurance, etc.

    How do some Cancer Cells survive Chemotherapy?

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Lamin B Receptor (LBR), Chemotherapy

    Mains level: NA

    cancer

    Central Idea

    • Researchers at the Netherlands Cancer Institute have conducted a recent study to investigate drug resistance in cancer cells, focusing on resistance to a drug known as Taxol.
    • It studied Chemotherapy and cancer relapse, particularly when a small number of cancer cells resist treatment and remain dormant, potentially leading to a resurgence of the disease.

    Chemotherapy and its limitations

    • Cancer cells are characterized by uncontrolled and rapid division.
    • Chemotherapeutic drugs aim to halt this proliferation, often triggering programmed cell death, known as apoptosis, in response to halted cell division.
    • However, this approach also damages healthy dividing cells, leading to adverse side effects.

    Fine-Tuning Cancer Treatment

    • Oncologists face the challenge of finding an effective drug dose that eliminates cancer cells while minimizing unbearable side effects for patients.
    • One approach has been the development of antibody-drug conjugates (ADCs) that target specific proteins found mainly on cancer cells, sparing non-cancerous cells.

    Unraveling Drug Resistance

    • P-gp Protein: Some cancer cells escape drug treatments by overexpressing a protein called P-gp (permeability glycoprotein), which acts as a pump, expelling toxic compounds, including chemotherapeutic agents.
    • ABCB1 Gene: The production of P-gp is controlled by the ABCB1 gene, and cells that produce excessive P-gp can flush out chemotherapy drugs, preventing them from accumulating at levels needed to trigger apoptosis.

    Role of Cellular Location

    • Recent Findings: The study examined the sensitivity of cells to Taxol and identified that the location of the ABCB1 gene within the cell’s nucleus plays a crucial role.
    • Nuclear Envelope: In sensitive cells, the ABCB1 gene is located close to the nuclear envelope. In resistant cells, the gene has detached from the envelope and moved further inside the nucleus, resulting in a 100-fold increase in ABCB1 gene-related RNA.

    Key Protein: Lamin B Receptor (LBR)

    • LBR’s Influence: Researchers discovered that the presence or absence of a protein called Lamin B Receptor (LBR) affects the location of the ABCB1 gene.
    • Depletion of LBR: When LBR is depleted, cells can activate the ABCB1 gene when exposed to Taxol. However, the absence of the LBR gene itself does not immediately increase ABCB1 expression, indicating the involvement of additional factors.
    • Diverse Responses: Different cancer types exhibit varying responses to LBR depletion, highlighting the complex mechanisms governing gene expression and silencing.
    • Analogy: A simple analogy illustrates the diversity: Different bathrooms offer various options for drying clothes, and cancer cell types rely on different mechanisms to tether genes to the nuclear envelope.

    Significance

    • These findings emphasize the need for further research into the diverse ways cancer cells express or suppress genes.
    • Understanding drug resistance mechanisms opens avenues for developing strategies to maintain the potency of anti-cancer drugs while minimizing side effects, ultimately benefiting patients on their path to recovery.
  • Corruption Challenges – Lokpal, POCA, etc

    Money Laundering Probe against a Political Party

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: PMLA

    Mains level: Money Laundering

    Central Idea

    • The Enforcement Directorate (ED) is contemplating adding a political party as an accused in a money laundering probe linked to the now-defunct Excise Policy of the Delhi government.

    Booking a Political Party for Money Laundering

    • Applicable Law: Section 70 of the Prevention of Money Laundering Act (PMLA) addresses offences by companies, and it can be invoked in this case.
    • Definition of “Company”: While a political party isn’t a ‘company’ under the Companies Act, the PMLA includes an explanation that broadens the scope to include ‘associations of individuals,’ potentially encompassing political parties.

    Precedent for such Cases

    • If pursued, this action could set a significant precedent in India’s legal landscape.
    • Previously, political parties have been investigated under the Income Tax Act.
    • Trusts and NGOs are already within the purview of the PMLA, as per a notification by the Finance Ministry.

    Connection between Charges and Political Party

    • The central allegation by the ED is that the political party received the proceeds of crime in the excise scam.
    • An additional explanation in Section 70 of the PMLA specifies that a “company may be prosecuted, notwithstanding whether the prosecution or conviction of any legal juridical person shall be contingent on the prosecution or conviction of any individual.”
    • This implies that even if cases involving party members fail, the party can still be prosecuted for money laundering separately.
  • Regional Comprehensive Economic Partnership (RCEP)

    Sri Lanka and Bangladesh explore RCEP Membership

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: RCEP

    Mains level: Read the attached story

    rcep

    Central Idea

    • Sri Lanka and Bangladesh are considering joining the Regional Comprehensive Economic Partnership (RCEP) after India’s withdrawal from the trade agreement in 2019.

    Recent update on RCEP

    • Sri Lanka’s Application: Sri Lanka has applied for RCEP membership and seeks support from China, Malaysia, Indonesia, Japan, and Thailand.
    • Bangladesh’s Decision: Bangladesh is expected to make a final decision on RCEP membership after its elections in January 2024.

    What is Regional Comprehensive Economic Partnership (RCEP)?

    Scope Free trade agreement among 15 Asia-Pacific countries
    Member Countries Australia, Brunei, Cambodia, China, Indonesia, Japan, Laos, Malaysia, Myanmar, New Zealand, Philippines, Singapore, South Korea, Thailand, Vietnam
    Negotiations and Signing Negotiations started in 2012,

    Officially signed on November 15, 2020

    Entry into Force Effective from January 1, 2022
    Objectives Reduce trade barriers, promote economic growth, enhance economic cooperation
    Trade Facilitation Includes tariff reductions, trade in services, rules of origin, customs procedures, and trade remedies
    Market Access Improves market access for goods and services among member countries
    Accession Rules Expected to be finalized by 2024
    Global Significance Significant due to large economies like China, Japan, and South Korea
    India’s Withdrawal India initially participated but withdrew in 2019 citing concerns about trade deficits and domestic industries

     

    India’s Stance on RCEP

    • Past Withdrawal: India withdrew from RCEP talks in 2019 due to concerns over services mobility, potential flood of Chinese goods, and objections from domestic agriculture and small businesses.
    • No Indication of Return: India has not indicated any reconsideration of its decision to withdraw from RCEP.

    Reasons for Sri Lanka and Bangladesh’s Interest

    • Learning from Crisis: Sri Lanka realizes the importance of regional markets during crises and hopes to spread its market and enhance competitiveness.
    • Bangladesh’s Graduation: As Bangladesh approaches graduation from the list of Least Developed Countries in 2026, joining RCEP could offset potential export losses and simplify FTA negotiations.
  • Health Sector – UHC, National Health Policy, Family Planning, Health Insurance, etc.

    Egypt attains WHO ‘Gold Tier’ status in Hepatitis C Elimination

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Hepatitis

    Mains level: Read the attached story

    Central Idea

    • Egypt has become the first country to achieve the World Health Organization’s “gold tier” status on the path to elimination of Hepatitis C.

    About Hepatitis

    Hepatitis A Hepatitis B Hepatitis C
    Causative Virus Hepatitis A Virus (HAV) Hepatitis B Virus (HBV) Hepatitis C Virus (HCV)
    Transmission Fecal-oral route (contaminated food/water) Blood and body fluids (unsafe sex, sharing needles) Blood-to-blood contact (sharing needles, transfusions)
    Vaccine Available Yes Yes Yes
    Chronic Infection No (usually acute) Yes (can become chronic) Yes (often becomes chronic)
    Symptoms Mild flu-like symptoms, jaundice Variable, from none to severe symptoms Often asymptomatic, but can lead to liver damage
    Chronic Complications None Cirrhosis, liver cancer Cirrhosis, liver cancer
    Preventable by Vaccine Yes Yes No
    Treatment Supportive care Antiviral medications Antiviral medications

     Egypt’s “Gold Tier” Status

    • Stringent Criteria: To reach the “gold tier,” Egypt fulfilled specific criteria, including ensuring 100% blood and injection safety, providing a minimum of 150 needles/syringes annually for people who inject drugs, diagnosing over 80% of individuals with chronic hepatitis C virus (HCV), treating over 70% of diagnosed HCV patients, and establishing a surveillance program for hepatitis sequelae, including liver cancer.
    • Exemplary Results: Egypt has diagnosed 87% of its hepatitis C patients and provided curative treatment to 93% of those diagnosed, surpassing the WHO’s gold tier targets.

    How did Egypt achieve this?

    • “100 Million Healthy Lives” Initiative: Egypt’s ambitious initiative led to a substantial reduction in hepatitis C prevalence, from 10% in 2016 to 5% in 2018 and an estimated less than 1% in 2019, as reported by the Africa CDC.
    • Leadership Role: Egypt extends support to other African countries, aiming to replicate its success in hepatitis C elimination, including enhancing access to affordable treatment.

    Try this PYQ:

    Which one of the following statements is not correct?

    (a) Hepatitis B virus is transmitted much like HIV.

    (b) Hepatitis B, unlike Hepatitis C, does not have a vaccine.

    (c) Globally, the number of people infected with Hepatitis B and C viruses are several times more than those infected with HIV.

    (d) Some of those infected with Hepatitis B and C viruses do not show the symptoms for many years.

     

    Post your answers here.

  • Foreign Policy Watch: India-Sri Lanka

    India-Sri Lanka Ferry Service

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: India-Sri Lanka Ferry

    Mains level: Read the attached story

    India-Sri Lanka Ferry Service

    Central Idea

    • PM Modi inaugurated an international, high-speed passenger ferry service in Palk Strait between Nagapattinam in Tamil Nadu, India, and Kankesanthurai, near Jaffna in Sri Lanka.

    India-Sri Lanka Ferry

    • The service is operated by the Tamil Nadu Maritime Board and Shipping Corporation of India.
    • It will operate daily, covering the 60-nautical mile (110-km) journey in approximately 3.5 hours.
    • Passengers are entitled to a 50kg free baggage allowance.
    • The Indo-Ceylon Express or Board Mail used to operate between Chennai and Colombo via Thoothukudi port.
    • However, this was stopped in 1982 due to the civil war in the island country.

    About Palk Strait

    Location Narrow water body separating Tamil Nadu, India, and Sri Lanka.
    Name Origin Named after Robert Palk, a British Raj-era governor of Madras Presidency (1755-1763).
    Geographic Boundaries Southern boundaries include Pamban Island (India), Adam’s Bridge (shoals), Gulf of Mannar, and Mannar Island (Sri Lanka).
    Connection Connects the Bay of Bengal in the northeast with the Gulf of Mannar in the southwest.
    Alternate Name Southwestern part of the strait is known as Palk Bay.
    Dimensions Width varies from 40 to 85 miles (64 to 137 km), length is approximately 85 miles, and depth is less than 330 feet (100 meters).
    River Inflows Vaigai River in Tamil Nadu flow into the Palk Strait.
  • Innovations in Biotechnology and Medical Sciences

    CAR-T Cell Therapy approved for Cancer

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: CAR-T Cell Therapy

    Mains level: Not Much

    car-t

    Central Idea

    • The Drug Controller General of India (DCGI) has granted market authorization to CAR-T (Chimeric Antigen Receptor-T) cell therapy, a groundbreaking cancer treatment developed by ImmunoACT, an IIT-Bombay spin-off.
    • This authorization paves the way for its commercial introduction in India.

    About CAR-T Cell Therapy

    What is it?

    • CAR-T cell therapy stands for chimeric antigen receptor T cell therapy.
    • It is a type of cancer immunotherapy that uses the patient’s own T cells, genetically modified in a laboratory to enhance their ability to locate and destroy cancer cells.

    How does it work?

    • T cells are white blood cells responsible for identifying and fighting illness and infection.
    • Each T cell has a receptor that can recognize antigens (proteins or molecules recognized by the immune system).
    • Cancer cells may have antigens that the immune system does not recognize as abnormal, allowing cancer to evade the immune response.
    • CAR-T cells are genetically engineered in the lab to express a new receptor that can bind to cancer cells and effectively kill them.

    Therapy Process

    The process involves several steps, including:

    1. Collecting T Cells: Blood is drawn from the patient’s arm, and T cells are separated from the blood using an apheresis machine.

    2. Engineering T Cells: In a laboratory, the T cells are modified by adding a manufactured CAR, and they are allowed to multiply and grow.

    3. Infusing CAR-T Cells: Once enough CAR-T cells are prepared, they are injected back into the patient’s arm.

    • Chemotherapy may be recommended before CAR-T cell infusion to enhance treatment effectiveness.
    • The process can take place in an outpatient infusion center or a hospital setting.

    Cancers Treated

    • CAR-T cell therapy is effective against certain types of cancer, especially when other treatments are ineffective.
    • It is currently FDA-approved for treating haematological malignancies, including leukemia, lymphoma, and multiple myeloma.
  • Innovations in Biotechnology and Medical Sciences

    Diverse Epigenetic Epidemiology Partnership (DEEP)

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: DNA Methylation

    Mains level: NA

    Central Idea

    • CSIR-Centre for Cellular and Molecular Biology (CCMB) is spearheading a groundbreaking research endeavour called the “Diverse Epigenetic Epidemiology Partnership (DEEP)”.
    • This integrated genomics and epigenomics study aims to unravel the genetic underpinnings of NCD’s prevalent in diverse populations, including South Asians.

    Diverse Epigenetic Epidemiology Partnership (DEEP)

    • DEEP is an integrated genomics and epigenomics study focused on understanding the genetic factors behind Non-Communicable Diseases (NCDs) in diverse populations, including South Asians.
    • The project spans five years.
    • It aims to uncover the impact of genomic and environmental diversity on disease risk observed in people worldwide, including those in Asia, Africa, North America, and South America.
    • It will study individuals from various genetic and environmental contexts to identify DNA methylation patterns contributing to disease risk in each context.
    • It will develop software, infrastructure, and conduct advanced statistical analyses to create new resources.
    • This will complement international health and genetics databases and examine trends in DNA methylation variation.

    DNA Methylation

    • DNA methylation is a process in which chemical groups attach to DNA, regulating the activation and deactivation of genes.
    • This epigenetic modification helps the body respond to environmental signals and contributes to overall health and disease status.
    • Understanding the relationships between DNA methylation, genetics, and the environment is crucial for comprehending the pathways governing health, disease, and their consequences.

    Significance of this initiative

    • This research will enable the identification of disease-causing mechanisms that are common worldwide and those which are unique to particular groups or regions.
    • It will help with answering questions such as whether medicines developed in one part of the world will be effective for all.
    • Ultimately the DEEP study hopes to enable targeted interventions or treatments and reduce global health disparity and inequity.
  • Mother and Child Health – Immunization Program, BPBB, PMJSY, PMMSY, etc.

    Abortion Rights in India: Legal Complexities and Ethical Dilemmas

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: MRTP Act

    Mains level: Abortion vs. Mothers Bodily Rights

    abortion

    Central Idea

    • CJI DY Chandrachud said that India’s abortion law was liberal, pro-choice and far ahead of other countries.
    • SC is hearing the case of a married woman who wants to medically terminate her 26-week pregnancy.
    • This raises critical questions about a woman’s autonomy in deciding to abort and the existing legislative framework.

    Woman’s Perspective

    • Unplanned Pregnancy: A 27-year-old married woman, already a mother of two, contends that her pregnancy was unplanned.
    • Financial Strain: She argues that her family’s income is inadequate to support another child, and she is undergoing treatment for postpartum depression after her second child’s birth.

    Court Decisions and AIIMS Report

    • Initial Approval: A two-judge Bench initially allowed the termination, reasoning that an unplanned pregnancy due to contraceptive failure is akin to a forced pregnancy, permitting abortion up to 24 weeks.
    • AIIMS Concern: AIIMS, Delhi, raised questions about whether foeticide (stopping the foetal heart) could be performed before termination since the foetus is currently viable.
    • Three-Judge Bench: The case was transferred to a three-judge Bench, led by Chief Justice of India (CJI) D Y Chandrachud, which called for a fresh medical report to assess the foetus’s health and the woman’s medical condition.

    Understanding the Abortion Law

    • Medical Termination of Pregnancy Act (MTP Act): The MTP Act allows termination of pregnancy in three stages.
      1. Termination up to 20 weeks with the advice of one doctor.
      2. Pregnancy at 20-24 weeks requires the opinion of two registered medical practitioners, under specific conditions.
      3. After 24 weeks, a medical board in approved facilities assesses the termination based on substantial foetal abnormalities.

    Court’s History of Allowing Late-Term Abortion

    • Several Precedents: The court has previously permitted terminations beyond 26 weeks in various cases, often in cases of rape or consensual relationships.
    • Marital Status Factor: The current case distinguishes itself by the woman’s marital status, implying that the conception is consensual and not a forced pregnancy.

    Balancing Rights: Woman vs. Unborn Child

    • Ongoing Debate: The CJI-led Bench oscillates between prioritizing a woman’s rights over abortion and the need to balance the rights of the unborn child.
    • Liberal Approach: India’s law on abortion is considered liberal and pro-choice, with courts often favouring the woman’s autonomy.

    Comparisons with International Standards

    • Foetal Viability: The concept of “foetal viability” as a benchmark for abortion approval is relatively new in India. It aligns with international standards.
    • US Roe v Wade: The landmark 1973 US Supreme Court case, Roe v Wade, allowed abortion until foetal viability. In 1973, viability was at 28 weeks, now lower due to scientific advancements.
    • Criticism of Indian Law: Some critics argue that India’s law lacks clarity as the decision to terminate after 20 weeks falls on doctors rather than the women, leading to frequent court interventions.

    Autonomy vs. Unborn Child’s Rights

    • Legislative Gap: While the Indian legal framework supports a woman’s autonomy in reproductive decisions, gaps persist, especially concerning last-minute interventions.
    • Ethical Debate: The Indian law leans toward women’s autonomy, but ethical dilemmas arise regarding the rights of the unborn child.
    • Legal Precedents: Cases like Nand Kishore Sharma versus Union of India have debated the constitutionality of the MTP Act concerning the right to life of an unborn child.

    Conclusion

    • The ongoing Supreme Court case highlights the intricate legal and ethical considerations surrounding abortion in India.
    • While the law supports a woman’s right to choose, the challenge lies in finding a delicate balance between individual autonomy and the rights of the unborn child.
    • As the court grapples with this complex case, it underscores the need for continued legal discourse and potential legislative amendments to address evolving reproductive rights issues.
  • Climate Change Impact on India and World – International Reports, Key Observations, etc.

    Large Ozone Hole detected over Antarctica

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Ozone Hole

    Mains level: Not Much

    ozone

    Central Idea

    • Satellite measurements conducted over Antarctica have unveiled a gigantic hole in the ozone layer.
    • Termed an “ozone-depleted area,” this region spans 26 million square kilometers (10 million square miles), approximately three times the size of Brazil.

    Ozone Layer and Ozone Hole

    Location Stratosphere, approximately 10-30 km above Earth’s surface.
    Composition Composed of ozone (O3) molecules.

    Unit of measurement: Dobsob Unit (DU)

    Function Acts as a protective shield, absorbing and blocking a significant portion of harmful ultraviolet (UV) radiation from the sun.
    Importance Essential for protecting life on Earth by preventing excessive UV radiation, which can harm living organisms and the environment.
    Ozone-depleting Substances Threatened by ODS like chlorofluorocarbons (CFCs), halons, and other synthetic compounds commonly used in refrigeration, air conditioning, and aerosol propellants.
    Montreal Protocol An international treaty adopted in 1987 to phase out the production and consumption of ODS, resulting in significant recovery of the ozone layer.
    Current Status The ozone layer is in the process of recovery due to the success of the Montreal Protocol.
    Environmental Impact Protects ecosystems, prevents skin cancer, cataracts, and other health issues in humans.
    Additional Facts • The size of the ozone hole over Antarctica varies annually, opening in August and closing in November or December.

    • Special winds caused by the Earth’s rotation create a unique climate over Antarctica, preventing mixing with surrounding air.

    • When these winds subside, the hole closes.

    Potential Causes of the Giant Ozone Hole

    • Volcanic Eruption in Tonga: Scientists speculate that the extensive ozone hole this year may be linked to volcanic eruptions in Hunga Tonga, Tonga, between December 2022 and January 2023. These eruptions released water vapor and other elements into the stratosphere, impacting the ozone layer through chemical reactions.
    • Human-Induced Ozone Holes: In the 1970s, scientists discovered that human activities, primarily the use of chlorofluorocarbons (CFCs), led to significant ozone depletion. These chemicals released chlorine in the stratosphere, depleting the ozone layer.
    • Effective Mitigation: The Montreal Protocol, established in 1987, aimed to combat ozone depletion by phasing out ozone-depleting substances. This international agreement successfully reduced the size of ozone holes over the years.

    Ozone Depletion and Climate Change

    • Not a Primary Climate Change Cause: Ozone depletion is not a leading contributor to global climate change.
    • Impact of Rising Temperatures: However, rising global temperatures may influence ozone holes. Extreme fires, such as those in southeastern Australia in 2020 and 2021, injected smoke into the stratosphere, potentially contributing to ozone depletion.
    • Changing Seasons: Ozone holes can alter the progression of seasons, as they extend the duration of polar vortexes, thereby extending winter periods.
  • GI(Geographical Indicator) Tags

    Recent GI tags awarded

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: GI tags mentioned

    Mains level: NA

    Central Idea

    • Many GI tags were awarded in this month. Let’s take a look:

    GI Tags in News:

    [1] Jaderi Namakatti

    Jaderi Namakatti gi tag

    • Jaderi namakatti are clay sticks that are white in colour, usually available in finger-like shape with a smooth texture.
    • They are used to adorn the foreheads of idols, men and temple elephants.
    • Jaderi is a small village in Tiruvannamalai district of Tamil Nadu.
    • There are around 120 families in Cheyyar taluk whose primary occupation has been making namakatti for more than hundreds of years now.

    [2] Basohli Pashmina

    Basohli Pashmina gi tag

    • Basohli Pashmina is a very old craft from the Kathua district of Jammu and Kashmir. It’s famous because it’s super soft, very fine, and feels incredibly light.
    • Pashmina is a type of material that is hand-spun and known for being incredibly soft, fine, lightweight, and also warm.
    • You can make various things from Pashmina, like shawls for men and women, mufflers, blankets, and even baskets.
    • It comes from a type of mountain goat called Capra hircus. These goats are found on the Changthang Plateau in Tibet and parts of Ladakh.
    • In Ladakh, there are people called the Changpa, who are known for making Pashmina wool. They live on the Changthang plateau in Tibet and are nomadic, which means they move around a lot.

    [3] Marcha Rice

    • Grown in select pockets of six blocks in West Champaran district, Bihar, India. These blocks include Mainatar, Gaunaha, Narkatiaganj, Ramnagar, Lauriya, and Chanpatia.
    • It has received a Geographical Indication (GI) tag, indicating its unique qualities associated with the region where it’s grown.
    • Cultivated by the Marcha Dhan Utpadak Pragatisheel Samuh, a registered organization of paddy cultivators in West Champaran district.
    • Known for its distinct aroma and taste, Marcha Rice is a special indigenous variety of paddy.

    [4] Atreyapuram Pootharekulu

    Atreyapuram Pootharekulu gi tag

    • Atreyapuram Pootharekulu is a traditional sweet originating from Atreyapuram village, situated on the banks of the Godavari River in the Konaseema district of Andhra Pradesh.
    • The name ‘Pootharekulu’ translates to ‘coated sheets,’ although this description may appear somewhat vague.
    • This traditional sweet is known for its extraordinary delicacy and distinct taste.
    • It is created by layering paper-thin sheets of rice flour, which are delicately coated with ghee (clarified butter) and then folded to encase powdered jaggery or sugar dust.
    • Additionally, some variants of Pootharekulu may include finely chopped roasted dry fruits such as pistachios, almonds, and cashews.
    • The preparation of relies on a specific type of rice known as MTU-3626, referred to locally as Bondalu.
    • This rice variety is chosen for its unique taste and its ability to yield a sticky consistency, which is crucial for crafting this sweet.

    Back2Basics: GI Tag

    • A GI is a sign used on products that have a specific geographical origin and possess qualities or a reputation that are due to that origin.
    • Nodal Agency: Department for Promotion of Industry and Internal Trade (DPIIT), Ministry of Commerce and Industry
    • India, as a member of the World Trade Organization (WTO), enacted the Geographical Indications of Goods (Registration and Protection) Act, 1999 w.e.f. September 2003.
    • GIs have been defined under Article 22 (1) of the WTO Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) Agreement.
    • The tag stands valid for 10 years.