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  • Digital India Initiatives

    Centre publishes Draft National Deep Tech Startup Policy

    deep tech

    Central Idea

    • The office of the Principal Scientific Adviser to the Government released a draft National Deep Tech Startup Policy (NDTSP) for public feedback.

    What is Deep Technology?

    • Deep Tech refers to advanced and sophisticated technologies that have a significant impact on various industries.
    • These technologies are complex, innovation-driven, and often require interdisciplinary collaboration.
    • Examples include AI, robotics, nanotechnology, quantum computing, biotechnology, and renewable energy solutions.
    • Deep Tech has the potential to revolutionize existing processes and address global challenges.

    About National Deep Tech Startup Policy (NDTSP)

    • The policy aims to secure India’s position in the global deep tech value chain, with a focus on areas such as semiconductors, Artificial Intelligence (AI), and space tech.
    • It aims to bolster research and development in deep tech startups, streamline intellectual property regimes, provide financing support, and promote the growth of these startups through various measures.

    Key objectives:

    • Focus on Fundamental and Technical Problems: The NDTSP emphasizes support for deep tech startups focusing on fundamental and technical challenges rather than just commercializing existing technologies.
    • Financing Support: The policy addresses the critical financing needs of deep tech startups, especially during the pre-market phase when they introduce their products or ideas.
    • Streamlined Intellectual Property Regime: The policy aims to simplify the intellectual property landscape for deep tech startups to encourage innovation without undue complexities.
    • Ease of Regulatory Compliance: The NDTSP proposes measures to ease regulatory requirements for deep tech startups, creating a conducive environment for their growth.
    • Commercialization Support: The policy suggests providing assistance and resources to effectively manage and commercialize technologies developed by deep tech startups.

    Measures to Promote Deep Tech Startups

    • Export Promotion Board: The NDTSP recommends creating an Export Promotion Board to facilitate Indian deep tech startups’ entry into foreign markets.
    • Coordinated Oversight: To streamline the deep tech ecosystem, the policy recommends establishing an “Inter-Ministerial Deep Tech Committee” to review and coordinate requirements effectively.
    • International Collaboration and Market Access: The policy promotes strategic international collaborations and partnerships to enhance market access for Indian deep tech startups globally.
    • Defense and Space Sector Focus: The NDTSP specifically targets deep tech startups in defense and space sectors, aiming to enhance their contributions to national security and space exploration.

    Attracting Global Talent and Expertise

    • Networking Opportunities: The policy advocates providing networking opportunities to international deep-tech startups and experts interested in contributing to India’s local ecosystem.
    • Resource-Intensive Approaches: The NDTSP emphasizes resource-intensive measures to attract global talent, strengthening India’s deep tech capabilities.
    • Visa and Immigration Facilitation: The policy proposes simplifying visa and immigration processes to attract foreign experts and investors to support the growth of deep tech startups.

    Need for such policy

    • 1997 Information Technology Agreement-I: The policy restates the government’s disappointment with international agreements, particularly the Information Technology Agreement-I. As an ITA participant, India made commitments to eliminate tariffs on a wide range of IT products.
    • Multi-pronged Approach: The NDTSP advocates a coordinated, comprehensive strategy to engage with international partners and multilateral institutions to foster a supportive global environment for India’s deep tech ecosystem.
    • Global Advocacy and Trade Policy Alignment: The policy emphasizes global advocacy to align trade policies with the interests of India’s deep tech startups, fostering a supportive international trade environment.

    Conclusion

    • The NDTSP aims to position India as a leader in the global deep tech value chain.
    • Public feedback on the draft policy will further refine and strengthen India’s approach to deep tech entrepreneurship.

    Back2Basics: Information Technology Agreement-I

    • ITA-I is a multilateral trade agreement that aims to eliminate tariffs and trade barriers on a wide range of information technology (IT) products.
    • It was negotiated under the auspices of the World Trade Organization (WTO) and came into effect on July 1, 1997.

    Key Points about ITA:

    1. Objective: By removing tariffs and trade barriers, the agreement aims to encourage the development and adoption of IT products and services worldwide.
    2. Product Coverage: The ITA covers a broad range of IT products, including computers, computer peripherals, telecommunications equipment, semiconductors, software, and other IT-related goods.
    3. Participants: Over time, the number of participants has expanded, and as of my knowledge cutoff in September 2021, it included more than 80 WTO member countries.
    4. Binding Commitments: Once a country joins the ITA, its tariff removal commitments become legally binding under the WTO framework.
    5. Non-Tariff Barriers: While the ITA focuses on eliminating tariffs, it does not directly address non-tariff barriers to trade, such as regulatory barriers or technical requirements.
  • Minimum Support Prices for Agricultural Produce

    MSP as a legal right: Pros and Cons

    What’s the news?

    • For years, farmers have been demanding a legal guarantee of the minimum support price (MSP), calculated according to the Swaminathan Commission formula.

    Central idea

    • The significance of MSP lies in its role in maintaining agricultural viability and preventing farmers from falling into debt and bankruptcy. However, the current MSP system falls short of its objectives, leaving most farmers without much-needed support. This op-ed emphasizes the need for a farmer-centric agricultural policy and a radical shift in approach to secure MSP with a legal guarantee.

    Minimum support price (MSP)

    • MSP is the price at which the government procures crops directly from farmers. It is calculated to be at least one-and-a-half times the cost of production incurred by the farmers.
    • The MSP serves as a minimum guaranteed price for specific crops that the government considers remunerative and deserving of support for farmers.

    Agriculture’s Role in the National Economy

    • Employment and Livelihood: Agriculture is the largest source of employment and livelihood for about 50 percent of the country’s population, especially in rural areas. It provides direct and indirect employment for millions of people.
    • Contribution to GDP: Agriculture contributes around 17–18 percent to India’s Gross Domestic Product (GDP). Although the share of agriculture in the overall GDP has been declining over the years due to the growth of other sectors, it remains a crucial component of the economy.
    • Food Security: The agricultural sector plays a critical role in ensuring food security for the nation. By producing a variety of food crops like rice, wheat, pulses, fruits, and vegetables, it caters to the dietary needs of the population and helps manage food inflation.
    • Source of Raw Materials: Agriculture is the primary source of raw materials for various industries, including textiles, sugar, jute, and vegetable oil. It provides the necessary inputs for industrial production, contributing to the overall industrial growth of the country.
    • Export Earnings: Agricultural exports, such as rice, spices, tea, coffee, and cotton, generate foreign exchange earnings for the country. This helps improve the balance of trade and supports economic growth.
    • Rural Development: The growth of agriculture has a significant impact on rural development. It improves rural infrastructure, raises the standard of living, and creates opportunities for the development of allied industries and services in rural areas.
    • Poverty Alleviation: Agriculture remains an essential tool in poverty alleviation as it provides income and employment opportunities to the rural population, which is often more susceptible to poverty.

    Important role of MSP

    • Ensuring Income Security: MSP provides a minimum guaranteed price for farmers’ produce. It protects them from price fluctuations and market risks, ensuring a stable income for their efforts and investment in farming.
    • Preventing Distress Sales: With MSP in place, farmers are less likely to resort to distress sales of their crops during times of market downturns.
    • Encouraging Crop Diversification: The MSP system covers a range of crops, including cereals, pulses, oil seeds, and more. By providing a remunerative price for diverse crops, it encourages farmers to adopt crop diversification, contributing to agricultural sustainability and food security.
    • Government Procurement: MSP sets a benchmark for government procurement of crops. The government procures crops at MSP through various agencies like FCI and state agencies, thereby supporting farmers and maintaining buffer stocks for food distribution.
    • Addressing Regional Imbalances: MSP implementation considers regional variations in production costs and helps bridge the income gap between farmers in different regions. It addresses regional imbalances and ensures equitable growth in the agriculture sector.

    Inadequacies of the MSP

    • Limited Coverage: The current MSP system leaves the majority of farmers without much-needed support. Only around 6% of farmers in the country benefit from MSP, while the remaining face challenges in accessing remunerative prices for their produce.
    • Debt and Bankruptcy: Despite MSP being introduced as a safety net, farmers still struggle with debt and bankruptcy. The average debt burden on a farmer’s family is over Rs 1 lakh, despite the subsidies provided by the government.
    • Natural Disasters and Market Risks: Farmers remain vulnerable to natural disasters and market forces, making their income uncertain and apprehensive. Climate change adds complexity to farming, and farmers cannot be left at the mercy of such unpredictable factors.
    • Insufficient Market Regulation: Middlemen exploit farmers, leading to a significant difference between the price at which farmers sell their produce and the price at which consumers buy the same produce. This lack of market regulation affects farmers’ income adversely.
    • Inadequate MSP Calculation: The MSP calculation method may not fully reflect the input costs, market trends, and other economic factors, leading to an ineffective MSP for farmers.
    • Rising Debt: The outstanding loan on farmers has increased significantly over the years, indicating the insufficiency of MSP and minimal increases in support prices.

    Swaminathan Commission Recommendations

    • Calculation of MSP: The Swaminathan Commission recommended that MSP be calculated by adding 50 percent profit to the C2 cost (comprehensive cost including imputed value of family labor) for crops. This method takes into account various input costs incurred by farmers, including labor, seeds, fertilizers, and other expenses.
    • Expanded Coverage: The Commission suggested expanding the scope of MSP to cover a wide range of agricultural produce, including crops like ginger, garlic, turmeric, chili, and all agricultural produce and horticulture.

    The Call for a Legal Guarantee of MSP

    • Addressing Rising Debts: The outstanding loan to farmers has significantly increased over the years, reaching Rs 23.44 lakh crore in 2021–22. Legalizing MSP would offer a sustainable solution, reducing farmers’ dependence on debt.
    • Fulfilling Promises: A legal guarantee makes MSP a binding obligation, ensuring farmers receive the promised prices for their crops and avoiding selling at lower rates.
    • Empowering Farmers: Legalized MSP enhances farmers’ bargaining power and enables informed decisions in cropping and marketing.
    • Supporting Sustainable Agriculture: MSP legislation promotes sustainable agriculture, diversification, and resilience against climate change.
    • Promoting Farmer-Centric Policy: A Legal Guarantee of MSP emphasizes a farmer-centric approach, safeguarding their rights, interests, and livelihoods.

    Way forward

    • Reforming Agribusiness and Ensuring Fair Compensation:
      1. Promote farmer producer organizations (FPO’s) and cooperatives.
      2. Facilitate direct market access to reduce dependence on intermediaries.
    • Adhering to the Swaminathan Commission’s Guidelines:
      1. Follow the MSP calculation as per the Swaminathan Commission’s recommendations.
      2. Consider comprehensive costs, including labor and input expenses.
    • Promoting Sustainable Agriculture Practices:
      1. Encourage the adoption of sustainable farming practices and climate-resilient crop varieties.
      2. Invest in agricultural research and extension services for modern technologies.
    • Ensuring Access to Credit and Insurance:
      1. Strengthen credit facilities for farmers.
      2. Provide insurance coverage to manage risks effectively.
    • Investing in Rural Infrastructure:
      1. Improve irrigation facilities, storage, and transportation networks.
      2. Reduce post-harvest losses and improve market access.
    • Promoting Agro-tourism and Direct Marketing:
      1. Encourage agro-tourism for additional income.
      2. Establish farmers’ markets and e-commerce platforms for direct marketing.

    Conclusion

    • The demand for a legal guarantee of MSP is a just and crucial step towards safeguarding the livelihoods of farmers. Providing farmers with a dignified life is not just a moral obligation but an economic imperative, as the growth of the agricultural sector directly impacts the nation’s prosperity.
  • Biofuel Policy

    LPG consumption in Indian households saw an absolute reduction in 2023

    What’s the news?

    • For the first time, LPG consumption in Indian households saw an absolute reduction in 2023 (minus 0.5% versus FY22) after years of steady growth.

    Central idea

    • Over the past 15 years, the Government of India has endeavored to replicate the urban success of LPG adoption in rural and poorer households. The Grameen Vitrak Yojana and Pradhan Mantri Ujjwala Yojana (PMUY) have significantly expanded the rural distributor base from 18% to 60%. However, the recent decline in LPG consumption raised questions about its sustainability and highlighted the need for a transition.

    Significant growth in the LPG sector

    • Share Increase: The share of Indian households using LPG as their primary cooking fuel rose from 33% in 2011 to 71% in 2020, according to the India Residential Energy Consumption Survey (IRES) conducted by the Council on Energy, Environment, and Water (CEEW).
    • Pradhan Mantri Ujjwala Yojana (PMUY): The successful implementation of PMUY, launched in May 2016, played a pivotal role in promoting LPG adoption. Over 8 crore (80 million) free LPG connections were provided to women from Below Poverty Line (BPL) households by March 2021.
    • Reduction of Health and Environmental Hazards: The increased adoption of LPG has led to a reduction in health hazards caused by traditional cooking fuels like firewood, crop residues, and dung cakes. Indoor air pollution, particularly affecting women who spent long hours cooking in smoky kitchens, has decreased.
    • Government Initiatives: Government policies and initiatives aimed at promoting clean cooking solutions have contributed to the growing awareness among Indian households about the benefits of LPG as a clean fuel for cooking

    Challenges faced by the LPG sector

    • Financial Barriers: The withdrawal of LPG subsidies for all consumers during the COVID-19 pandemic in 2020 created financial barriers for many households, affecting their ability to afford LPG refills.
    • Underutilization of Subsidies: Despite providing three free cylinders to all PMUY consumers in FY21 as part of the Pradhan Mantri Garib Kalyan Yojana, only 14.1 crore out of the possible 24 crore free cylinders were consumed, indicating challenges in reaching the intended beneficiaries and ensuring full utilization of the provided benefits.
    • Distribution and Logistics: Despite significant efforts, home delivery and distribution channel issues persisted, particularly affecting non-PMUY consumers, leading to slow refill rates and hindering the seamless supply of LPG.
    • Price Volatility: Indian households have experienced a near-doubling in LPG prices since May 2020 in nominal terms due to volatile international prices, especially since the Russian war against Ukraine. This price volatility affects the affordability and accessibility of LPG for consumers.
    • Import Dependency: India’s dependence on imported LPG (the refined commodity) has steadily increased to over 64% in FY23, compared to 46% in the pre-PMUY phase. This import dependency exposes the country to international market risks and supply disruptions.
    • Budgetary Constraints: Given the domestic budget’s reliance on petroleum taxation and uncertain international prices, it is unlikely that India can return to a regime where a subsidy of approximately INR 20,000 crore (2011–12 prices) was provided each year for LPG consumption over the first two decades of the 21st century.

    Steps and a data-driven approach for India’s clean cooking transition

    • Promote Electric Cooking: India should actively promote electric cooking, including induction cook-tops, to offset the reliance on flame-based cooking. The IRES conducted by CEEW showed that even at a high tariff of ₹8 per unit of electricity, electric cooking remains cheaper than LPG cooking at current prices.
    • Leverage Electricity Access in Rural Areas: With near-universal access to electricity connections in rural areas, specific cooking needs can be shifted to electricity. This approach can effectively reduce the reliance on LPG in rural households.
    • Incentivize Transition to Electric Cooking: Policymakers can use a telescopically increasing LPG prices beyond a threshold, such as seven cylinders per average household.
    • Support Domestic Manufacturing Ecosystem: Demand from early adopters of electric cooking can spur the domestic manufacturing ecosystem for electric cooking technologies.
    • Monetize Avoided Emissions: By transitioning from traditional chulhas to electric cooking, India can avoid climate pollutant release. This can be monetized through the newly launched carbon market, providing financial resources to support the adoption of electric cooking by poorer rural communities.
    • Shift the Policy Focus: Policymakers need to move beyond LPG subsidies alone and focus on fostering a bouquet of solutions for India’s clean cooking goals.

    Conclusion

    • While LPG subsidies have played a crucial role in improving adoption, it is time for India’s clean cooking policy to diversify and embrace a range of clean-cooking technologies. By nurturing a bouquet of clean cooking solutions, India can pave the way for a sustainable and healthier future.
  • Blockchain Technology: Prospects and Challenges

    WorldCoin: Building a Global Digital Network with Biometric Identity

    worldcoin
    PC: The Hindu

    Central Idea

    • OpenAI CEO Sam Altman recently reintroduced Worldcoin, a project that was previously overshadowed by the popularity of ChatGPT.

    What is WorldCoin?

    • The Worldcoin venture involves a unique model where individuals have their eyes scanned to establish their human uniqueness.
    • In return for the eye scan, participants receive cryptocurrency and a World ID, forming the basis of the project.
    • Worldcoin’s aim is to create the “world’s largest identity and financial public network,” accessible to people globally.

    How does it works?

    • Orb Operators: Worldcoin relies on volunteers called “Orb operators” who use a device called “Orb” to scan people’s iris patterns and collect their biometric data.
    • World ID: Participants receive a World ID through the World app after getting their irises scanned. This unique ID allows them to claim Worldcoin cryptocurrency and conduct transactions.
    • Proof of Personhood: Scanning irises ensures that people cannot sign up multiple times to receive more crypto rewards.
    • Cryptocurrency and Transactions: Users can collect WLD at regular intervals or use it for transactions, similar to a standard digital currency.

    WLD Cryptocurrency and Compliance

    • WLD Token: WLD is a cryptocurrency based on the Ethereum blockchain and can be bought, sold, or traded on major exchanges.
    • Regulatory Compliance: Worldcoin ensures compliance with Europe’s GDPR and uses zero-knowledge proofs (ZKPs) to maintain user privacy. User data is encrypted and not sold, though it may be shared with necessary third parties.

    Various risks

    • Price Volatility: As with most cryptocurrencies, the price of WLD is subject to fluctuations. Its value can rise or fall, and users should be cautious about investing in lesser-known digital currencies.
    • Security Risks: Users must be wary of potential scams or hacks related to cryptocurrency investments.

    Criticism and Controversies

    • Privacy Concerns: Worldcoin faced criticism over privacy concerns about the use of biometrics for verification.
    • Scanning in Emerging Economies: Reports indicated that Worldcoin scanned underprivileged people’s irises in emerging economies during the COVID-19 pandemic, raising ethical questions about informed consent and rewards for scans.

    Worldcoin in India

    • Orb Operators in India: Worldcoin has deployed Orb operators in various locations, particularly in Delhi, Noida, and Bangalore, where people’s irises are scanned to join the network.

    Conclusion

    • Worldcoin’s vision of a global digital network with biometric identity and cryptocurrency rewards is both promising and controversial.
    • While it aims to foster financial inclusion and provide digital opportunities, it must address privacy and ethical concerns to gain wider acceptance and trust among users worldwide.
  • Innovations in Biotechnology and Medical Sciences

    Potential of Cell-Free DNA (cfDNA) in Disease Research

    DNA

    Central Idea

    • Researchers worldwide are increasingly using Cell-free DNA (cfDNA) as a valuable tool to better comprehend human diseases, improve diagnosis, monitoring, and prognosis.

    What is Cell-free DNA?

    • CfDNA refers to small fragments of nucleic acids that are released from cells and found outside the cell in body fluids.
    • Its discovery dates back to the late 1940s when it was first observed in the blood of pregnant women.
    • cfDNA can be generated and released from cells in various situations, such as cell death and other physiological processes.
    • The release of cfDNA is associated with several disease processes, including autoimmune diseases like systemic lupus erythematosus.

    How is it different from normal DNA?

    Cell-free DNA

    Normal DNA

    Found in the bloodstream and other bodily fluids Found within the cell nucleus or mitochondria
    Released from dying or dead cells into the circulation Remains within the cell’s nucleus or mitochondria
    Exists in a fragmented form Exists as an intact double-stranded helix
    Can be isolated and analyzed from blood samples Requires cell extraction and purification for analysis
    Provides valuable genetic information for personalized medicine Forms the basis of genetic inheritance and traits
    Valuable in infectious disease diagnosis and monitoring Not used for infectious disease diagnosis
    Used in forensics for DNA profiling and crime investigations Not typically used in forensics

     

    Applications of CfDNA

    Non-Invasive Prenatal Testing (NIPT) Detect genetic abnormalities in foetuses

    Screening for Down syndrome, Edwards syndrome, and Patau syndrome

    Cancer Screening and Monitoring Identify genetic mutations in tumour cells

    Determine cancer type

    Monitor treatment response and disease progression

    Transplant Rejection Monitoring Monitor immune response after organ transplantation

    Early detection of organ rejection

    Infectious Disease Diagnosis Identify viruses and bacteria in the bloodstream

    Aid in diagnosing infections and guiding treatment

    Personalized Medicine Provide genetic information for tailored treatment plans

    Enable precision medicine based on individual genetic profile

    Tracking Tumour Mutations Monitor drug-resistant mutations in cancer patients for treatment adjustments

     

    Recent Advances in Therapeutics

    • GEMINI Test: Researchers at Johns Hopkins Kimmel Cancer Centre developed a new test called ‘GEMINI’ that uses cfDNA for early cancer detection. By analyzing genetic mutations and using machine learning, they achieved over 90% accuracy in detecting lung cancer, even in early-stage cases.
    • Potential Impact: Early detection of cancers using cfDNA could significantly improve patient outcomes and survival rates.
  • The Crisis In The Middle East

    Israel Judicial Reform Explained: What is the crisis about?

    israel

    Central Idea

    • On July 24, the governing coalition in Israel’s Parliament (Knesset) passed a critical part of its judicial overhaul plan, aimed at curbing the Supreme Court’s oversight powers over government decisions.
    • This has sparked months of protests against the right-religious government’s plans to transform the judiciary.

    Judiciary Overhaul: The Crisis Trigger

    • Abolishing the “Reasonability Doctrine”: The Knesset legislation abolishes the “reasonable doctrine” used by the Supreme Court to assess government decisions and ministerial appointments. This doctrine allowed the court to determine the sensibility and fairness of government decisions and nullify them if deemed necessary.
    • Reasonability Doctrine in Other Countries: The reasonability standard is a legal standard used in several countries, including Australia, Canada, and the U.K., by top courts to evaluate government decisions.
    • Criticism and Justification: Supporters of the government argue that the reasonability standard is too abstract and prone to judicial overreach, justifying its removal. They claim that this change will prevent courts from interfering in executive decisions.

    Other Proposals in the Overhaul Plan

    • Curbing Judicial Review: The original overhaul plan included proposals to limit judicial review over legislation and empower Parliament to override court decisions with a majority vote of 61 out of 120.
    • Greater Control of Judicial Appointments: The government seeks to replace members of the Bar Association in the nine-member panel responsible for selecting judges with “public representatives” chosen by the government. This change would give the government a majority vote in the committee and more control over judicial appointments.
    • Ministers’ Autonomy from Legal Advisers: Another proposal seeks to remove the legal obligation for Ministers to follow the advice given by their legal advisers, including the Attorney-General’s guidance.

    Motivation behind the Overhaul

    • Right-Wing Government’s Agenda: Israel’s current government, composed of right-wing, ultra-Orthodox, and extreme-right parties, aims to strengthen its control over the judiciary. The right-wing leaders have criticized the judiciary for impeding their legislative agenda and settlement expansion in Palestinian territories.
    • Shift in Israel’s Polity: Over the years, Israel’s polity has shifted rightward, while the judiciary remained relatively independent. The right-wing has long advocated for bringing the courts under the Parliament’s ambit.
    • Influence of Think Tank: The Kohelet Policy Forum, a think tank backed by American and Israeli billionaires, has played a significant role in formulating the judicial reforms. Kohelet seeks to advance right-wing policy reforms in Israel and has pushed for the overhaul of the judiciary.

    Protests and Concerns

    • Undermining Democracy: Critics, including the Opposition and civil society, argue that the government’s actions are an attempt to undermine Israel’s democracy. They fear that concentrating power within the government, controlled by right-wing and religious parties, could lead to an authoritarian theocracy.
    • Tensions between Liberal and Orthodox Jews: Protests have spread to different groups, including military reservists, amid concerns that religious parties may undermine the courts and empower religious sections.
    • Supreme Court Review: Civil society groups have filed petitions in the Supreme Court challenging the legislation on the reasonability doctrine. The court, facing a constitutional showdown, will review the challenges, even though the law curtails its own powers.

    Conclusion

    • The passage of the judicial overhaul plan in Israel’s Knesset has significant implications for the country’s governance and democratic fabric.
    • The concentration of power within the government and curtailing the Supreme Court’s oversight powers has raised concerns about checks and balances.
    • Civil society’s petitions and the Supreme Court’s subsequent decisions will be crucial in determining the future course of Israel’s judiciary and its democratic institutions.
  • Tuberculosis Elimination Strategy

    BPaL Trial yields 85% TB Cure Rate

    tb

    Central Idea

    • The interim results of a randomized phase-3/4 trial conducted in India to evaluate the safety and effectiveness of BPaL Regimen, an all-oral, short-course treatment are promising.
    • BPaL is administered for individuals with pre-XDR TB or treatment-intolerant/non-responsive MDR pulmonary TB

    What is BPaL?

    • The trial uses only three drugs—Bedaquiline, Pretomanid, and Linezolid (BPaL).
    • The treatment duration is only 26 weeks, contrasting with the conventional 18-month treatment involving eight to nine tablets per day.

    Trial Outcomes

    • It offered a significantly reduced number of tablets per day, resulting in better treatment adherence and improved outcomes.
    • Approximately 70% of the trial participants have completed the 26-week treatment, with a cure rate exceeding 85%.
    • In comparison, the cure rate for conventional treatment for DR-TB is 60-65% even with strict adherence.

    Treatment Superiority

    • Advanced TB Cases: The trial participants had advanced TB affecting both lungs, yet the cure rate was above 85%, demonstrating the superiority of the BPaL short-course therapy.
    • Importance of Early Diagnosis: Early diagnosis and initiation of treatment with the three-drug regimen can lead to even better outcomes for patients with pre-XDR TB.

    Issues with the treatment

    • Three to four trial participants experienced serious adverse effects, but these were either managed or occurred too late in the disease’s progression to be helped.
    • Some cases of mild adverse effects caused by linezolid included a drop in haemoglobin and platelet counts, as well as neuropathy (tingling sensation and numbness in the legs).

    TB Menace in India

    • Total TB Cases: In 2021, there were approximately 21.3 lakh (2.13 million) reported TB cases in India.
    • Incidence Rate: The incidence rate of TB in India in 2021 was 210 cases per lakh population.
    • Drug-Resistant TB: The number of drug-resistant TB cases in India declined from around 1.49 lakh in 2015 to 1.19 lakh in 2021.
    • Government Initiatives: To combat TB, India has set the target of eliminating the disease by 2025, and various initiatives have been implemented, including active case finding, screening, and improved access to diagnostic tests and treatment.

    Back2Basics:

    XDR TB (Extensively Drug-Resistant TB)

    Treatment-Intolerant/Non-Responsive MDR Pulmonary TB

    Resistant to most effective first-line and some second-line TB drugs. Patient cannot tolerate prescribed medications or infection does not respond to treatment.
    More dangerous and difficult to treat than MDR TB. Requires exploration of alternative treatment regimens.
    Limited treatment options, higher mortality, and increased transmission risk. Adjustments in drug combinations or dosages may be needed.
    Spreads rapidly, posing a serious public health threat. Crucial to prevent development of extensively drug-resistant strains.
    Requires preventive measures and early diagnosis. Identifying reasons for treatment intolerance and providing support.

     

  • Electronic System Design and Manufacturing Sector – M-SIPS, National Policy on Electronics, etc.

    Mapping India’s Chip Design Ecosystem

    chip

    Central Idea

    • The Indian government is considering a proposal to pick an equity stake in domestic chip design-making companies as part of the second phase of the Design-Linked Incentive (DLI) Scheme for the semiconductor industry.
    • The aim behind the scheme is to establish a stable ecosystem and promote the growth of “fabless companies” in India—entities that design chips but outsource manufacturing.
    • However, this policy requires a long-term strategy due to the capital-intensive nature of the semiconductor sector and the lengthy gestation periods for setting up design and fabrication units.

    What is DLI Scheme?

    What is Design Linked Incentive (DLI) Scheme? - Civilsdaily

    • DLI scheme is a program aimed at providing financial and infrastructural support to companies establishing semiconductor manufacturing plants in India.
    • Eligible participants who set up fabrication units in the country can receive fiscal support of up to 50% of the total cost.
    • Additionally, participants building compound semiconductors, silicon photonics, and sensors fabrication plants can avail fiscal support of 30% of the capital expenditure under this scheme.
    • Companies engaged in semiconductor design for integrated circuits, chipsets, system-on-chips, systems, and IP cores will receive incentives of 4% to 6% on net sales for a duration of five years.
    • The scheme is expected to promote the growth of at least 20 such companies, achieving a turnover of more than ₹1500 crore in the next five years.

    Present Chip Dynamics

    • Long Gestation Period: Setting up design and fabrication units in the semiconductor industry involves long gestation periods before the first product is launched. Returns on investment are not immediate.
    • Capital Intensive: The semiconductor industry requires significant investment for setting up fabrication units, up-scaling manufacturing capabilities, and research.
    • Cyclic Nature: The industry’s cyclic nature and changing functional requirements of chipsets make research and development challenging.
    • Supply Chain Disruptions: Supply chain disruptions, such as those experienced during COVID-related lockdowns, can dampen investor confidence in the sector.

    Domestic Chip Industry Scenario

    • Talent Pool: India has a highly-skilled talent pool of semiconductor design engineers, making up around 20% of the world’s workforce, working for global companies like Intel, Micron, and Qualcomm, among others.
    • IP Ownership: Despite a thriving talent pool, India owns a smaller portion of the intellectual property (IP) related to chip designs, which is mostly retained by global companies.
    • DLI Scheme for Chip Designing: The DLI scheme introduced in December 2021 aimed to indigenize innovations and support the growth of chip design companies with financial incentives.
    • Changing Landscape: The scheme has led to the establishment of over 30 semiconductor design startups in India, with some already receiving government support.

    Growing market in India

    • The semiconductor industry is growing fast and can reach $1 trillion dollars in this decade. India can grow fast and reach $64 billion by 2026 from $27 billion today.
    • Mobiles, wearables, IT, and industrial components are the leading segments in the Indian semiconductor industry contributing around 80% of the revenues in 2021.
    • The mobile and wearables segment is valued at $13.8 billion and is expected to reach $31.5 billion in 2026.

    Challenges and Considerations

    • Effectiveness and Efficiency: Some experts view the government’s plan to become a venture capital firm for chip design companies as ineffective and inefficient. Companies may prefer foreign buyers for higher valuations and global ecosystem connections.
    • Venture Capital Support: The lack of venture capitalists in the private sector focused on semiconductors is a challenge for the growth of design firms.
    • Equity Stake’s Impact: Offering an equity stake can align the interests of design companies with the project’s success, ensuring shared risk and reward. It may also help in selling chip-designing services more effectively and attracting a broader client base in the market.
    • IP and Value-Added Activities: The government must consider who can keep the IP and how investments can drive more innovation and employment generation. Moving up in the value chain and enabling the ecosystem is crucial.

    Conclusion

    • The proposal to take an equity stake in domestic chip design-making companies in India’s semiconductor industry aims to promote the growth of fabless companies and ensure a stable ecosystem.
    • However, it requires a long-term strategy and careful consideration of IP ownership, venture capital support, and value-added activities in chip design.
    • The success of the scheme will depend on effective implementation and alignment of interests between the government and promising design companies.
  • Civil Aviation Sector – CA Policy 2016, UDAN, Open Skies, etc.

    Need for Overhaul in UDAN Scheme

    udan

    Central Idea

    • Union Civil Aviation Ministry inaugurated a new phase of the Ude Desh Ka Aam Nagrik (UDAN) scheme, or UDAN 5.2, to improve last-mile connectivity in remote regions of the country through small aircraft.
    • There have been aspersions regarding the success of the UDAN regional connectivity scheme (RCS) since ONLY 11 of the 74 Greenfield airports are decently operational.

    Progress till now

    • Route Closures: Out of the 479 routes launched under RCS, 225 have ceased operations, leading to significant route closures.
    • Commercial Viability: Around 70 of the routes were found to be commercially unviable even with subsidies, leading airlines to discontinue their operations.
    • Three-Year Sustainability: The objective of RCS was for airlines to become self-sustaining after three years, but only 58 out of 155 routes completed this period successfully.
    • Incomplete Infrastructure: Some airports, such as Thanjavur, Moradabad, Saharanpur, and Ayodhya, were not ready for operations, leading to the discontinuation of 12 routes.

    What is UDAN Scheme?

    • UDAN Scheme, initiated in 2016, aims to enhance aviation infrastructure and air connectivity in Tier II and Tier III cities.
    • It was formulated based on the review of The National Civil Aviation Policy (NCAP)-2016, with the goal of fulfilling the aspirations of the common citizen.
    • The scheme, designed to last for 10 years, operates with a self-financing mechanism through the establishment of the Regional Connectivity Fund (RCF).
    • The RCF funds the viability gap funding (VGF) requirements of the scheme by levying certain domestic flights, thereby stimulating growth and development in the aviation sector.
    • As part of the scheme, the Airports Authority of India has waived the airport fee.

    Issues with the scheme

    • Route Discontinuance: Some routes launched under UDAN have been discontinued, raising concerns about their sustainability.
    • Challenges in Expansion: Efforts to improve connectivity to hilly regions and islands through helicopters and seaplanes have faced hurdles due to land unavailability and operational difficulties.
    • Unrecovered since the Pandemic: The COVID-19 pandemic has adversely affected the aviation industry, further impacting the sustainability of airlines.

    Various Challenges

    • Financial Constraints: Many smaller airlines struggle with insufficient funds, making it difficult to maintain aircraft, pay rentals, and provide staff salaries.
    • Maintenance Issues: Smaller players often have limited aircraft that are poorly maintained, and acquiring new planes is expensive.
    • Pilot Availability: The availability of pilots can be a challenge for smaller airlines, leading to higher costs when hiring foreign pilots.
    • Competition: Routes dominated by bigger domestic players like IndiGo and SpiceJet tend to see better success rates.

    Way Forward

    • Extended Subsidy Period: Airlines need an extension of the subsidy period to develop routes sustainably and achieve self-sufficiency.
    • Addressing Pandemic Impact: The impact of the COVID-19 pandemic on travel restrictions and passenger safety should be considered when evaluating the losses incurred by airlines.
    • Collaboration and Support: The government and stakeholders need to collaborate to address financial constraints and maintenance issues faced by smaller airlines.
    • Continuous Evaluation: Regular evaluation and necessary adjustments in the UDAN scheme are essential to overcome challenges and ensure successful implementation.

    Conclusion

    • While India has made significant strides in airport development, challenges related to commercial viability and infrastructure readiness must be addressed to ensure sustainable air connectivity across the nation.
    • Renewed focus on the UDAN scheme and optimizing airport infrastructure can pave the way for a robust aviation sector that benefits smaller cities and contributes to the overall growth of the nation’s economy.
  • Tiger Conservation Efforts – Project Tiger, etc.

    In news: International Tiger Day

    tiger

    Central Idea

    • July 29th was celebrated the world over as International Tiger Day in a bid to raise awareness on various issues surrounding tiger conservation.
    • India’s tiger population has witnessed significant growth over the past decade, owing to successful conservation efforts under the Project Tiger initiative.

    About International Tiger Day

    It was first instituted in 2010 at the Tiger Summit in St Petersburg, Russia when the 13 tiger range countries came together to create Tx2, the global goal to double the number of wild tigers by the year 2022.

    Celebrating 50 Years of Project Tiger

    • Historical Context: Project Tiger was launched in 1973 to promote the conservation of tigers when their population was alarmingly low, hovering around 2,000 due to hunting and habitat destruction.
    • Landmark Achievement: Over the past 50 years, India’s tiger population has made a remarkable recovery, standing at 3,167 in 2022 as compared to just 268 in 1973.

    tiger

    Population Growth and Distribution

    • Decade-wise Growth: The tiger population has shown a remarkable growth trajectory in recent years. In 2010, there were 1,706 tigers, which increased to 2,226 in 2014 and further rose to 3,582 in 2022.
    • Regional Distribution: In 2022, the states with the highest tiger populations were Madhya Pradesh (785), Karnataka (563), Uttarakhand (560), and Maharashtra (444). Nearly 25% of the tigers were reported outside protected areas.

    Conservation Efforts and Successes

    • Tiger Reserves: India’s tigers are mainly concentrated in 53 dedicated tiger reserves covering about 75,796 square km, which accounts for approximately 2.3% of the country’s total land area.
    • Successful Reserves: Reserves like Corbett National Park in Uttarakhand (260 tigers), Bandipur (150), and Nagarhole (141) in Karnataka have shown commendable success in tiger conservation.
    • Project Tiger: Launched in 1973, Project Tiger played a crucial role in conserving the species, ensuring not just the protection of tigers but also preserving their natural habitats.

    Challenges and Concerns

    • Habitat Fragmentation: The growing human population and developmental activities have led to the fragmentation of tiger habitats, affecting their dispersal and increasing human-tiger conflicts.
    • Quality of Forest Cover: The degradation of forest cover can impact prey availability and contribute to human-wildlife conflict, especially in regions like Central India and the Eastern Ghats.
    • Human-Wildlife Conflict: As tiger habitats shrink and corridors get disrupted, encounters between tigers and humans have increased, leading to conflicts and potential danger to both tigers and people.
    • Legal Framework Dilution: Some proposed amendments to environmental acts and the approval of projects in protected areas have raised concerns about the dilution of the legal framework supporting tiger conservation.

    Way forward

    • Development with Ecological Sensibility: Upcoming infrastructure projects, like highways, are being planned with safe passageways for tigers and other animals to ensure minimal disruption to their movement.
    • Relocation and Rehabilitation: Relocation of human settlements from core areas of tiger reserves is incentivized to increase protected land and improve tribal livelihoods.

    Conclusion

    • Conservation Commitment: The success of tiger conservation in India has come through the commitment of people, political will, and strong legal and policy frameworks.
    • Sustained Efforts: Despite the successes, continued efforts and vigilance are essential to ensure the continued growth of the tiger population and its harmonious coexistence with human communities.

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