💥UPSC 2026, 2027, 2028 UAP Mentorship (March Batch) + Access XFactor Notes & Microthemes PDF

Type: Prelims Only

  • Health Sector – UHC, National Health Policy, Family Planning, Health Insurance, etc.

    PM-CARES Fund

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: PM-CARES Fund

    Mains level: Not Much

    Our PM has called for donations to the newly instituted PM-CARES Fund which has been formed on popular demand to help fight the novel coronavirus.

    PM-CARES Fund

    • The fund will be a public charitable trust under the name of ‘Prime Minister’s Citizen Assistance and Relief in Emergency Situations Fund’.
    • The PM is Chairman of this trust and members include the Defence Minister, Home Minister and Finance Minister.
    • Contributions to the fund will qualify as corporate social responsibility (CSR) spending that companies are mandated to make.
    • The Fund accepts micro-donations as well.
  • Zoonotic Diseases: Medical Sciences Involved & Preventive Measures

    Indian Scientists’ Response to CoViD-19 (ISRC) Group

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Indian Scientists’ Response to CoViD-19 (ISRC)

    Mains level: Not Much

    Several Indian scientists have come together to form a Google group to address some of the concerns that the COVID-19 outbreak has thrown up.

    Indian Scientists’ Response to CoViD-19 (ISRC)

    • It is a voluntary group of scientists who regularly discuss the rapidly evolving situation with its dire need for science communication.
    • With nearly 200 members, the group has scientists from institutions such as the NCBS, the IISc, the TIFR, the IITs, the IISERs and many others.
    • The group aims to study existing and available data to bring out analyses that will support the Central, State and local governments in carrying out their tasks.

    Self-assigned tasks

    • Several working groups have been formed by scientists.
    • They include one on hoax busting to address disinformation spreading with respect to the coronavirus and one on science popularization to develop material that explains concepts such as home quarantine.
    • Other groups work on resources in Indian languages, mathematical models and apps.

    Why such a group?

    • The scientific community has realized their social and democratic responsibility in the current situation, both in terms of analysing the situation and reaching out to the public.
  • Zoonotic Diseases: Medical Sciences Involved & Preventive Measures

    Serological test for COVID-19

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: COVID 19 diagnosis

    Mains level: Coronovirus outbreak and its mitigation

    The ICMR invited bids for an estimated 10 lakh antibody kits (for serological tests) for the diagnosis of COVID-19.

    What are serological tests?

    • Viral infections are mainly identified by two kinds of tests– genetic and serological.
    • Genetic tests can identify infections that are active but cannot be used to detect past infections.
    • To trace how infections like the novel coronavirus have spread so far, it is important to detect people who contracted the disease in the past and have recovered.
    • This is what serological tests seek to determine.

    How are the two different?

    • The genetic test is conducted on a swab collected from the back of the throat, a liquid sample from the lower respiratory tract, or a simple saliva sample.
    • For SARS-COV-2, the virus’s RNA is first converted into DNA.
    • By a process called polymerase chain reaction (PCR), DNA fragments in the sample are copied exponentially — one is copied into two, the two are copied into four, and so on.
    • Unlike genetic tests, which look for RNA in swab samples, serological tests work on antibodies in blood samples. Hence, they are also called ‘antibody tests’.

    How serological tests work?

    • Antibodies, or protective proteins produced by the immune system to neutralize pathogens such as bacteria and viruses, are present in one’s bloodstream for a considerable period of time after the infection has gone.
    • To disable a pathogen, the antibody latches to a unique protein molecule on pathogen’s surface, called an antigen.
    • Serological tests use antigen molecules to detect the presence of antibodies relevant to the infection.
    • Generally, a blood sample is placed in a test tube that is lined with antigens on the inside. If the relevant antibodies are present, they latch on to the antigens.
    • Such tests are relatively inexpensive, and can display results within a few minutes.
  • Economic Indicators and Various Reports On It- GDP, FD, EODB, WIR etc

    What is Keqiang Index’?

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Keqiang Index

    Mains level: NA

    China’s GDP numbers which are preferably represented by Keqiang Index has been recently seen in news amid coronavirus outbreak.

    Keqiang Index

    • Li Keqiang index or Keqiang index is an economic measurement index created by The Economist to measure China’s economy using three indicators, as reportedly preferred by Li Keqiang.
    • It uses three other indicators:
    1. the railway cargo volume,
    2. electricity consumption and
    3. loans disbursed by banks
    • Li Keqiang currently the Premier of the People’s Republic of China, suggest the index as better economic indicator than official numbers of GDP.
  • Health Sector – UHC, National Health Policy, Family Planning, Health Insurance, etc.

    What is Hantavirus?

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Hantavirus

    Mains level: Rise in zoonotic diseases and their possible causes

    China has reported the death of a person from Yunnan Province who tested positive for the Hantavirus.

    What is Hantavirus?

    • The Hantaviruses are a family of viruses spread mainly by rodents. It is contracted by humans from infected rodents.
    • Cases of the Hantavirus in humans occur mostly in rural areas where forests, fields and farms offer suitable habitat for infected rodents.
    • A person can get infected if he/she comes in contact with a rodent that carries the virus.
    • In the US and Canada, for instance, the Hantavirus carried by the deer mouse is responsible for the majority cases of the Hantavirus infection.
    • Like this, there are various other kinds of Hantaviruses that find hosts in rodents, like the white-footed mouse and the cotton rat among others that may lead to infections in humans if transmitted.

    Its origin

    • The Hantavirus is not novel and its first case dates back to 1993, according to the US Centre for Disease Control (CDC).
    • In the Americas, the family of viruses is known as ‘New World hantaviruses’.

    Symptoms

    • A person infected with the virus may show symptoms within the first to eighth week after they have been exposed to fresh urine, faeces or the saliva of infected rodents.
    • Symptoms may include fever, fatigue, muscle aches, headaches, chills and abdominal problems.
    • Four to ten after being infected, late symptoms of HPS may start to appear, which include coughing and shortness of breath.

    Mortality risk

    • It is the cause of Hantavirus pulmonary disease (HPS), a severe respiratory disease. The HPS can be fatal and has a mortality rate of 38 per cent.
    • It remains unclear whether human-to-human transmission of the virus is possible.
    • There have been no reports of human-to-human transmission of Hantavirus in the US.
  • River Interlinking

    Danube-Oder-Elbe Canal

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Rivers mentioned in the newscard

    Mains level: Not Much

     

    Environmental organisations from across central and Eastern Europe have criticised a major project intending to link three rivers and provide seamless navigation between three of Europe’s peripheral seas, according to a statement.

    Danube-Oder-Elbe Canal

    • For centuries Europe’s rulers have dreamed of construction of a huge Y-shaped canal connecting the Elbe, Oder and Danube rivers, most of which would be on Czech territory.
    • The Canal intends to connect the Danube, Oder and Elbe rivers and thus provide another navigable link from the Black Sea to the North and Baltic Seas.
    • The Main-Danube Canal already provided a navigable connection between the Black Sea and the North Sea.
    • Several hundred kilometres of artificial waterways would have to be built for the canal, according to the statement.
    • Critics have called on the European Commission to ensure that the project be excluded from EU funding, and not be included as part of the Trans-European Transport Network.
  • Modern Indian History-Events and Personalities

    Persons in news: Sheikh Mujibur Rahman

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Sheikh Mujib and his legacy

    Mains level: NA

    March 17 is the birth anniversary of Bangabandhu Sheikh Mujibur Rahman (1920-1975), the founding leader of Bangladesh and the country’s first Prime Minister.

    Sheikh Mujibur Rahman

    Sheikh Mujibur Rahman in 1950.jpg

    • Before joining politics, Rahman studied law and political science in Kolkata and Dhaka and agitated for Indian independence.
    • He is referred to as Sheikh Mujib or simply Mujib, the title ‘Bangabandhu’ meaning ‘friend of Bengal’.
    • In 1949, he joined the Awami League, a political party which advocated greater autonomy for East Pakistan.
    • A popular leader in East Pakistan, Rahman played an important role in the six-point movement and the Anti-Ayub movement.

    Role in Bangladesh liberation

    • In 1970, his party secured an absolute majority in the Pakistani general elections; the country’s first, winning more seats than all parties in West Pakistan, including Zulfikar Ali Bhutto’s Pakistan People’s Party.
    • The election results were not honoured; leading to a bloody civil war, and Sheikh Mujib declared Bangladesh’s independence from Pakistan on March 26, 1971.
    • The declaration coincided with a ruthless show of strength by the Pakistani military, in which tanks rolled out on the streets of Dhaka and several students and intellectuals were killed.
    • India under then PM Indira Gandhi provided full support to Rahman and Bangladesh’s independence movement, resulting in the creation of a sovereign government at Dhaka in January 1971.

    His legacy

    • Rahman, who had been arrested and taken to West Pakistan, returned to Bangladesh after being freed in January 1972.
    • For the next three years, Rahman held the new country’s prime ministerial post, and became a celebrated icon in India as well, admired for his moving speeches and charismatic personality.
    • On 15 August 1975, Rahman was killed in a military coup along with his wife and three sons, including 10-year-old Sheikh Russel.
    • His daughters, the current Prime Minister Sheikh Hasina and her younger sister Sheikh Rehana, survived as they were abroad at the time.
  • Tax Reforms

    Excise Duty on Petrol and Diesel

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Excise duty

    Mains level: Changes in taxation after GST regime

    The Central levies on petrol and diesel were hiked amid sliding global crude oil prices. But the price of petrol and diesel registered a decline after oil companies further cut auto fuel prices in light of the substantial fall in global crude oil prices.

    What is Excise Duty?

    • Excise duty is a form of tax imposed on goods for their production, licensing and sale.
    • It is the opposite of Customs duty in sense that it applies to goods manufactured domestically in the country, while Customs is levied on those coming from outside of the country.
    • At the central level, excise duty earlier used to be levied as Central Excise Duty, Additional Excise Duty, etc.
    • Excise duty was levied on manufactured goods and levied at the time of removal of goods, while GST is levied on the supply of goods and services.

    Purview of excise duty

    • The GST introduction in July 2017 subsumed many types of excise duty.
    • Today, excise duty applies only on petroleum and liquor.
    • Alcohol does not come under the purview of GST as exclusion mandated by constitutional provision.
    • States levy taxes on alcohol according to the same practice as was prevalent before the rollout of GST.
    • After GST was introduced, excise duty was replaced by central GST because excise was levied by the central government. The revenue generated from CGST goes to the central government.

    Types of excise duty in India

    Before GST kicked in, there were three kinds of excise duties in India.

    Basic Excise Duty

    • Basic excise duty is also known as the Central Value Added Tax (CENVAT). This category of excise duty was levied on goods that were classified under the first schedule of the Central Excise Tariff Act, 1985.
    • This duty was levied under Section 3 (1) (a) of the Central Excise Act, 1944. This duty applied on all goods except salt.

    Additional Excise Duty

    • Additional excise duty was levied on goods of high importance, under the Additional Excise under Additional Duties of Excise (Goods of Special Importance) Act, 1957.
    • This duty was levied on some special category of goods.

    Special Excise Duty

    • This type of excise duty was levied on special goods classified under the Second Schedule to the Central Excise Tariff Act, 1985.
    • Presently the central excise duty comprises of a Basic Excise Duty, Special Additional Excise Duty and Additional Excise Duty (Road and Infrastructure Cess) on auto fuels.
  • Innovations in Biotechnology and Medical Sciences

    Role of Glucose in Regulating Liver Functions

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: SIRT1

    Mains level: NA

    A study by researchers from the Tata Institute of Fundamental Research, Mumbai (TIFR) has revealed that glucose in the body controls the function of SIRT1 enzymes directly.

    What is SIRT1?

    • SIRT1 is an enzyme that deacetylates (removal of acetyl) proteins which contribute to cellular regulation.
    • A shortage or absence of the control by glucose may lead to a diabetic-like state, while excess feeding and sustained low levels of SIRT1 can lead to obesity and enhanced ageing.
    • This information is expected to tackle lifestyle disorders and ageing-related diseases.

    How do they function?

    • In normal healthy individuals, SIRT1 protein levels are known to increase during fasting and decrease during the feed, which is essential to maintain a balance between glucose and fat metabolism.
    • The glucose controls the functions of a protein SIRT1 which in turn maintains everyday feed-fast cycles and is also associated with longevity.
    • The feed-fast cycle is a basic pattern and the metabolism-related to this is largely taken care of by the liver.
    • Thus, the study shows that both over-activation and under-activation of SIRT1 can lead to diseases.
    • Glucose puts a check on the activity of SIRT1 in the fed state. In the absence of this check, SIRT1 activity increases and results in hyperglycemia in a fasted state, mimicking diabetic state.
    • The constant feeding or high-calorie intake that leads to a sustained reduction in the levels of SIRT1 by glucose which is associated with ageing and obesity.
  • New Species of Plants and Animals Discovered

    Oculudentavis khaungraae

    Scientists have found the skull of a 99-million-year-old flying dinosaur that is tinier than the tiniest bird known to humans.

    • The bird-like dinosaur was found stuck in a gob of tree resin that eventually hardened into amber, preserving it for millions of years to come.
    • The fossil was dug up in 2016 from a mine in Myanmar. It was so slight; it likely weighed just 2 grams.
    • The dinosaur skull holds around 100 sharp teeth, which hints at its ferocious nature despite its small size.
    • It even had teeth in the back of its jaw, under its eye.