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Type: Prelims Only

  • Wildlife Conservation Efforts

    Species in news: Asiatic Lions in Kuno National Park

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Asiatic Cheetah

    Mains level: Species reintroduction and related issues

    Experts have argued that the introduction of African cheetahs to Kuno National Park could endanger the Asiatic lion which has also been identified for re-introduction.

    Do you know?

    Cheetahs had a more extensive distribution than lions — there are no records of lions occurring south of the Narmada River, but Asiatic cheetahs roamed most of India until they were hunted to extinction by 1947.

    About Asiatic Cheetah

    • Cheetah, the world’s fastest land animal was declared extinct in India in 1952.
    • The Asiatic cheetah is classified as a “critically endangered” species by the IUCN Red List, and is believed to survive only in Iran.
    • It was expected to be re-introduced into the country after the Supreme Court lifted curbs for its re-introduction.
    • From 400 in the 1990s, their numbers are estimated to have reached to 50-70 today, because of poaching, hunting of their main prey (gazelles) and encroachment on their habitat.

    Why reintroduce Cheetahs?

    • Reintroductions of large carnivores have increasingly been recognized as a strategy to conserve threatened species and restore ecosystem functions.
    • The cheetah is the only large carnivore that has been extirpated, mainly by over-hunting in India in historical times.
    • India now has the economic ability to consider restoring its lost natural heritage for ethical as well as ecological reasons.

    Why was the project halted?

    • The court was worried whether the African cheetahs would find the sanctuary a favorable climate as far as the abundance of prey is concerned.
    • Those who challenged the plan argued that the habitat of cheetahs needed to support a genetically viable population.

    Issues with cheetah re-introduction

    • Since 2018, dozens of lions have died from diseases, including canine distemper, opening up a frightening possibility of loss when confined to a single location.
    • Establishing an additional free-ranging wild lion population in Kuno is of paramount importance and roadblocks, if any, must be transparently addressed.
    • Clearly, the introduction of African cheetahs cannot take precedence over translocating Asiatic lions from Gujarat to Kuno National Park as ordered by none other than the apex court in 2013.
    • However, simultaneous re-introduction can create a conflict for prey between these two wild cats.

     

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  • Blockchain Technology: Prospects and Challenges

    Carbon Footprints of Cryptocurrencies

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Cryptocurrencies

    Mains level: Carbon footprint of cryptocurrencies

    Bitcoin prices are rising these days and so will be its mining. As cryptocurrency will become mainstream, its carbon footprint cannot be ignored.

    What are Cryptocurrencies?

    Cryptocurrency

    Global crypto market

    • In 2019, the global cryptocurrency market was approximately $793 million.
    • It’s now expected to reach nearly $5.2 billion by 2026, according to a report by the market research organization Facts and Factors.
    • In just one year—between July 2020 and June 2021—the global adoption of cryptocurrency surged by more than 880 percent.

    Carbon footprints of Bitcoins

    • Increasing popularity of cryptocurrency has environmentalists on edge, as the digital “mining” of it creates a massive carbon footprint due to the staggering amount of energy it requires.
    • A/c to the Bitcoin Energy Consumption Index, the carbon footprint of Bitcoin is equivalent to that of New Zealand.
    • Both emit nearly 37 megatons of carbon dioxide into the atmosphere every year.

    What is Mining?

    • Mining is a process in which computational puzzles are solved in order to verify transactions between users, which are then added to the blockchain.
    • In simpler terms, the works are created, or “minted,” through a process called proof-of-work (PoW), which establishes its unique identity.

    How do cryptocurrencies create such a footprint?

    • Unlike mainstream traditional currencies, bitcoin is virtual and not made from paper or plastic, or even metal.
    • Bitcoin is virtual but power-hungry as it is created using high-powered computers around the globe.
    • Bitcoin is created when high-powered computers compete against other machines to solve complex mathematical puzzles.
    • This is an energy-intensive process that often relies on fossil fuels, particularly coal, the dirtiest of them all.

    Conclusion

    • What this means is that, unlike traditional currency or gold, Bitcoin is not solely a settlement layer, not solely a store of value, and not solely a medium of exchange.
    • This makes Bitcoin’s relative energy consumption productive in comparison to comparative sectors, given its robust potential uses.
    • The promise of such an endeavor offers hope for a more sustainable cryptocurrency future.
    • Whether this will make much difference to the climate crisis in light of government and industrial inaction remains to be seen.

    Back2Basics: Bitcoin Energy Consumption Index

     

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  • Telecom and Postal Sector – Spectrum Allocation, Call Drops, Predatory Pricing, etc

    Millimeter Wave band in 5G auctions

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: 5G technology

    Mains level: Delay in roll-out of 5g

    The Telecom Regulatory Authority of India (TRAI) has asked for views on band plan, block size, and conditions for auction of spectrum in 5G bands, which includes Millimetre (mm) Wave band of 24.25-28.5 GHz.

    Must read:

    Status of 5G Rollout in India

    What is 5G technology?

    • 5G or fifth generation is the latest upgrade in the long-term evolution (LTE) mobile broadband networks.
    • It’s a unified platform that is much more capable than previous mobile services with more capacity, lower latency, faster data delivery rate and better utilisation of spectrum.

    5G spectrum

    5G mainly works in 3 bands, namely low, mid and high-frequency spectrum — all of which have their own uses as well as limitations.

    (1) Low band spectrum

    • It has a great promise in terms of coverage and speed of internet and data exchange but the maximum speed is limited to 100 Mbps (Megabits per second).
    • So Telcos can use and install it for commercial cell phone users who may not have specific demands for very high speed internet, the low band spectrum may not be optimal for specialized needs of the industry.

    (2) Mid-band spectrum

    • It offers higher speeds compared to the low band, but has limitations in terms of coverage area and penetration of signals.
    • This band may be used by industries and specialized factory units for building captive networks that can be moulded into the needs of that particular industry.

    (3) High-band spectrum

    • It offers the highest speed of all the three bands, but has extremely limited coverage and signal penetration strength.
    • Internet speeds in the high-band spectrum of 5G has been tested to be as high as 20 Gbps (giga bits per second), while, in most cases, the maximum internet data speed in 4G has been recorded at 1 Gbps.

    What is Millimetre (mm) Wave Band?

    • Millimetre Wave band or mmWave is a particular segment of radio frequency spectrum that range between 24 GHz and 100 GHz.
    • This spectrum, as the name suggests, has a short wavelength, and is apt to deliver greater speeds and lower latencies.
    • This in turn makes data transfer efficient and seamless as the current available networks work optimally only on lower frequency bandwidths.

    Significance of this mm band

    • 5G services can be deployed using lower frequency bands.
    • They can cover greater distances and are proven to work efficiently even in urban environments, which are prone to interference.
    • But, when it comes to data speeds, these bands fail to hit peak potential needed for a true 5G experience.
    • So, mmWave is that quintessential piece in the 5G jigsaw puzzle for mobile service providers.

    Concerns with inclusion of mm-band

    • The mm bands have been preserved for satellite-based broadband services as per the decision taken by the International Telecommunication Union (ITU).
    • Providing excess spectrum could pose a downside risk of the bands going unsold, or even worse, underutilised by terrestrial players at the expense of satellite-based service providers.
    • Offering excessive spectrum will result in Indian citizens being denied the benefits of high-demand, advanced satellite broadband services.
    • In addition to this, it will result in a massive loss to the Indian economy of up to $184.6 billion by 2030, along with the loss of foreign direct investment (FDI) and employment generation benefits.

    How could this disrupt the satellite communication industry?

    • Internet has largely been provided to users via fibre-optic based broadband connectivity or mobile network.
    • Of late, another class of Internet vendors is showing up. These are satellite-based communication service providers.
    • For example, SpaceX’s Starlink and Bharti Airtel’s OneWeb are some of the players in this market.
    • This segment uses Low-Earth Orbit (LEO) satellites to provide broadband to both urban and rural users. Their service could also be used for weather predictions.
    • The mm band had been the subject of controversy due to out-of-band emissions into the passive satellite band used for weather satellites at 23.6-24 GHz.

    HeaWay ahead

    • The allocation of mmWave band is critical to the satellite communication industry, which needs a stronger regulatory support to ensure that 5G operations don’t interfere with their existing operations.
    • The industry body pointed to Europe’s “5G Roadmap”, which is built on the ITU’s decision to hold these bands for satellite-based broadband services.

     

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  • Telecom and Postal Sector – Spectrum Allocation, Call Drops, Predatory Pricing, etc

    BARC ratings for news channels to resume soon

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: TRP

    Mains level: Read the attached story

    Ratings by Broadcast Audience Research Council (BARC) for the news channels will resume, after the organisation revised its procedures and protocols.

    The ratings were suspended after the Mumbai police busted a racket involving a private channel’s efforts to tamper the TRPs.

    Try this question:

    Q.What do you mean by “TRP Journalism”? Discuss the loopholes in the present system of self-regulation in Indian media.

    What is TRP?

    • In simple terms, anyone who watches television for more than a minute is considered a viewer.
    • The TRP or Target Rating Point is the metric used by the marketing and advertising agencies to evaluate this viewership.
    • In India, the TRP is recorded by the Broadcast Audience Research Council (BARC) using Bar-O-Meters that are installed in televisions in selected households.
    • As on date, the BARC has installed these meters in 44,000 households across the country. Audio watermarks are embedded in video content prior to broadcast.
    • These watermarks are not audible to the human ear, but can easily be detected and decoded using dedicated hardware and software.
    • As viewing details are recorded by the Bar-O-Meters, so are the watermarks.

    What is BARC?

    • It is an industry body jointly owned by advertisers, ad agencies, and broadcasting companies, represented by The Indian Society of Advertisers, the Indian Broadcasting Foundation and the Advertising Agencies Association of India.
    • Though it was created in 2010, the I&B Ministry notified the Policy Guidelines for Television Rating Agencies in India on January 10, 2014, and registered BARC in July 2015 under these guidelines, to carry out television ratings in India.

    How are the households selected?

    • Selection of households where Bar-O-Meters are installed is a two-stage process.
    • The first step is the Establishment Survey, a large-scale face-to-face survey of a sample of approximately 3 lakh households from the target population. This is done annually.
    • Out of these, the households which will have Bar-O-Meters or what the BARC calls the Recruitment Sample are randomly selected. The fieldwork to recruit households is not done directly by BARC.
    • The BARC on its website has said that the viewing behaviour of panel homes is reported to BARC India daily. Coincidental checks either physically or telephonically are done regularly.

    Vigilance activities by BARC

    • Certain suspicious outliers are also checked directly by BARC India.
    • BARC India also involves a separate vigilance agency to check on outliers that it considers highly suspicious.
    • And as per the guidelines of the Ministry of Information and Broadcasting, these households rotate every year.
    • This rotation is in such a manner that older panel homes are removed first while maintaining the representativeness of the panel.
    • The Ministry guidelines further say that the secrecy and privacy of the panel homes must be maintained, and asked the BARC to follow a voluntary code of conduct.

    What are the loopholes in the process?

    • Several doubts have been raised on many previous occasions about the working of the TRP.
    • As per several reports, about 70% of the revenue for television channels comes from advertising and only 30% from subscriptions.
    • It is claimed that households were being paid to manipulate the TRP.

     

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  • Air Pollution

    National Ambient Air Quality Standards (NAAQS)

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Various air pollutants

    Mains level: NAAQ standards

    Delhi and most of the other non-attainment cities under the National Clean Air Programme (NCAP) have shown only a marginal improvement, said a new analysis released.

    About NCAP

    • The NCAP was implemented across India in 2019 to reduce particulate matter levels in 132 cities by 20-30% in 2024.
    • Cities are declared non-attainment if they consistently fail to meet the National Ambient Air Quality Standards (NAAQS) over a five-year period.

    What are NAAQ standards?

    • The mandate provided to the Central Pollution Control Board (CPCB) under the Air (Prevention and Control of Pollution) Act empowers it to set standards for the quality of air.
    • Hence the current National Ambient Air Quality Standards were notified in November 2009 by the CPCB.
    • Prior to this, India had set Air Quality standards in 1994, and this was later revised in 1998.
    • The 2009 standards further lowered the maximum permissible limits for pollutants and made the standards uniform across the nation.
    • Earlier, less stringent standards were prescribed for industrial zones as compared to residential areas.

    Pollutants covered:

    • Sulphur Dioxide (SO2)
    • Nitrogen Dioxide (NO2),
    • Particulate Matter (size less than 10 µm) or PM 10
    • Particulate Matter (size less than 2.5 µm) or PM2.5
    • Ozone (O3)
    • Carbon Monoxide (CO)
    • Ammonia (NH3)

    (Air Pollutants that most of us NEVER heard of:)

    • Lead
    • Benzene (C6H6)
    • Benzo(a)Pyrene (BaP)
    • Arsenic(As)
    • Nickel (Ni)

    Source: Arthpaedia

     

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  • Monsoon Updates

    What is Samba Cultivation?

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Samba Cultivation

    Mains level: NA

    Around four lakh more acres have been brought under the Crop Insurance Scheme for the Samba Cultivation season of 2021-22 in Tamil Nadu.

    What is Samba Cultivation?

    • It is a Tamil name for paddy cultivation season.
    • Other paddy seasons in Tamil Nadu include:
    1. Kuruvai: June-July
    2. Samba: August
    3. Late Samba / Thaladi: September- October
    4. Navarai: December- January

    Back2Basics: Major crop seasons

    (1) Kharif Crop

    • Kharif crops, monsoon crops, or autumn crops are cultivated and harvested in the monsoon season.
    • The farmers sow seeds at the beginning of the monsoon season and harvest them at the end of the season. i.e., between September and October.
    • Kharif crops need a lot of water and hot weather for proper growth.
    • Examples: Rice, Maize, Millet, Soybean, Arhar, Cotton. etc.

    (2) Rabi Crop

    • Rabi means spring in Arabic. Crops grown in the winter season [October to December] and harvested in the spring season [Aril-May] are called Rabi crops.
    • These crops require a warm climate for germination and maturation of seeds and need a cold environment for their growth.
    • Rain in winter spoils the Rabi crop but is good for the Kharif crop.
    • Examples: Wheat, Gram, Barley, Peas, Oats, Chickpea, Linseed, Mustard, etc.

    (3) Zaid Crop

    • Zaid crops are grown between Kharif and Rabi Seasons, i.e., between March to June.
    • They require warm, dry weather as a vital growth period and longer day length for flowering.
    • Zaid crop is significant for farmers as it gives fast cash to the farmers and is also known as gap-filler between two chief crops, Kharif and Rabi.
    • Examples: Cucumber, Pumpkin, Bitter gourd, Watermelon, Muskmelon, Sugarcane, Groundnut, Pulses, etc.

     

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  • Modern Indian History-Events and Personalities

    Veer Baal Diwas to be observed on December 26

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Veer Bal Divas

    Mains level: Not Much

    Prime Minister has declared that December 26 shall henceforth be marked as Veer Baal Diwas to pay homage to the courage of the Sahibzades, four sons of Guru Gobind Singh, the last Sikh guru.

    What is the legend of Sahibzades?

    • The word “Sahibzada” means “son” in Punjabi and is a term commonly used to refer to the 4 sons of Guru Gobind Singh, the tenth Sikh Guru.
    • The week of 21 to 27 December is celebrated as the Sacrificial Week in memory of the four Sahibzadas who made sacrifices for the protection of Sikhism and Hinduism.
    • Sahibzada Ajit Singh, Jujhar Singh, Zorawar Singh and Fateh Singh got martyrdom while saving their religious faiths against forceful conversion.

    Their martyrdom: A backgrounder story

    • After the establishment of the Khalsa Panth, Guru Gobind Singh left the fort of Sri Anandpur Sahib with his family on 20-21 December 1704 to fight the invasion by Aurgangzeb.
    • The elder sahibzade Ajit Singh, Jujhar Singh stayed with Guru ji, while the younger sons Zorawar Singh and Fateh Singh were with Mata Gujri ji.
    • Subedar Wazir Khan of Sirhind arrested the two Sahibzades subsequently and lured them for religious conversion.
    • In the end, it was announced to get them elected in the living walls.
    • The rest two sahibzades got assassinated in the battle of Chamkaur (1705).

    Implications of their martyrdom

    • When the news of this reached Guruji, he wrote a zafarnama (letter of victory) to Aurangzeb, in which he warned Aurangzeb that the Khalsa Panth was ready to destroy your empire.
    • Baba Banda Singh Bahadur took revenge for the martyrdom of Guruji’s Sahibzadas.
    • He punished Wazir Khan for his deeds in Sirhind and established Sikh hegemony over the entire area.
    • The result of this sacrifice was that later a large Sikh empire emerged under the leadership of Maharaja Ranjit Singh.

    A historic event in Indian History

    • This event is an important part of Indian history and the occasion of their martyrdom is remembered and commemorated both with great vigor and sorrow.
    • The names of Sahibzades are reverently preserved and are recalled every time Ardas (prayer) of supplication is recited at a congregation or privately by an individual.

     

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  • Innovations in Biotechnology and Medical Sciences

    Zebrafish study reveals how the brain makes its connections

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Synapses, Human Brain

    Mains level: NA

    Recent work by researchers at the National Centre of Biological Sciences, Bengaluru, has thrown light on what stimulates the synapses (connection of nerve cells) to form.

    What are Synapses?

    • Neurons, or nerve cells, in the brain connect by means of junctions known as synapses through which they transmit signals.
    • There are two types of synapses – chemical and electrical:

    (1) Chemical Synapse

    • In this, there is a space of about 20 nanometres between two neurons, and the way they communicate is this: One neuron converts electrical signal into chemical signals.
    • This chemical is released into the synaptic space and the receiving neuron converts the chemical signal back into an electrical signal.

    (2) Electrical synapse

    • In these synapses, the two neurons have a physical connection and the conversion of electrical to chemical need not occur, and they communicate directly.
    • Electrical synapses are like a physical wire, communication is faster but they are also fewer in number.

    Observing these synapses

    • Researchers from TIFR-National Centre of Biological Sciences, Bengaluru, have chosen Zebrafish as a model organism to study this process.
    • Zebrafish are transparent and neuron development in larval zebrafish can be observed from day to day by injecting a dye or by engineering the fish to express fluorescent proteins.
    • It was observed that electrical synapses are formed before chemical synapses, they are like a blueprint in which neurons make a handshake. This results in the making of chemical synapses.
    • Research on organisms such as leeches showed that if you remove electrical synapses, the chemical synapses do not form.
    • However, the mechanism of how it happens in higher organisms such as vertebrates was not known.

    What induces these synapses?

    • The group observed that knocking out a particular protein known as the gap junction delta 2b (gjd2b) in the cerebellum of zebrafish affected levels of the enzyme CaMKII.
    • Levels of CaMKII were seen to increase in the Purkinje neurons in the cerebellum.
    • These neurons and the cerebellum itself control coordination of movements in the organism.

    Why study this?

    • In humans for example, excess abuse of alcohol leads to damage of these cells, which results in lack of coordination in movement.
    • The cerebellum shows an evolutionary continuity in all vertebrates, so, too, the Purkinje neurons.
    • Even though fish and humans diverged from a common ancestor about 500 million years ago, the cerebellum has been evolutionarily conserved.
    • While zebrafish have about 300-400 Purkinje neurons, humans have thousands of these.

     

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  • Economic Indicators and Various Reports On It- GDP, FD, EODB, WIR etc

    What are the First Advance Estimates of GDP?

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: GDP computation and various terminologies

    Mains level: National Income Accounting

    The Ministry of Statistics and Programme Implementation (MoSPI) has released the First Advance Estimates (FAE) for the current financial year (2021-22 or FY22).

    Tap to read more about:

    National Income Determination, GDP, GNP, NDP, NNP, Personal Income

    What is GDP?

    • GDP measures the monetary value of all goods and services produced within the domestic boundaries of a country within a timeframe (generally, a year).
    • It is slightly different from the other commonly used statistic for national income — the GNP.
    • The Gross National Product (GNP) measures the monetary value of all goods and services by the people and companies of a country regardless of where this value was created.

    GDP estimates for FY22

    • According to MoSPI, India’s GDP will grow by 9.2 per cent in 2020-21.
    • Last financial year, FY21, the GDP had contracted by 7.3%.

    What are the First Advance Estimates of GDP?

    • The FAE, which were first introduced in 2016-17, are typically published at the end of the first week of January.
    • They are the “first” official estimates of how GDP is expected to grow in that financial year.
    • But they are also the “advance” estimates because they are published long before the financial year (April to March) is over.
    • It is important to note that even though the FAE are published soon after the end of the third quarter (October, November, December), they do not include the formal Q3 GDP data.
    • Q3 data is published at the end of February as part of the Second Advance Estimates (SAE).

    Significance of FAE

    • Budgetary calculations: Since the SAE will be published next month, the main significance of FAE lies in the fact that they are the GDP estimates that the Union Finance Ministry uses to decide the next financial year’s budget allocations.
    • Basis for nominal GDP: From the Budget-making perspective, it is important to note what has happened to nominal GDP — both absolute level and its growth rate. That’s because nominal GDP is the actual observed variable.

    Note: Real GDP, which is the GDP after taking away the effect of inflation, is a derived metric. All Budget calculations start with the nominal GDP.

    Real GDP = Nominal GDP — Inflation Rate

    The difference between the real and nominal GDP shows the levels of inflation in the year.

    How are the FAE arrived at before the end of the concerned financial year?

    Ans. Benchmark-Indicator method

    • The FAE are derived by extrapolating (uses ratio and proportion) the available data.
    • The approach for compiling the Advance Estimates is based on Benchmark-Indicator method.
    • In this, the estimates available for the previous year (2020-21 in this case) are extrapolated using relevant indicators reflecting the performance of sectors.”

    What are the main takeaways?

    #1 GDP Growth

    • At 9.2%, the real GDP growth rate for FY22 is slightly lower than most expectations, including RBI’s, which pegged it at 9.5%.
    • These estimates are based on data before the rise of the Omicron variant.

    #2 Role of high inflation

    • For FY22, while real GDP (with 2011-12 base prices) will grow by 9.2%, nominal GDP (calculated using current market prices) will grow by a whopping 17.6%.
    • The difference between the two growth rates — about 8.5 percentage points — is essentially a marker of inflation (or the rate at which average prices have increased in this financial year).

    #3 Private consumption continues to struggle

    • The FAE analyses the three main contributors to GDP — private consumption demand, investments in the economy, and government expenditures.
    • It shows that while the latter two are expected to claw back to the pre-Covid level, the first engine will continue to stay in a slump.

    #4 Average Indian is much worse off

    • For the bulk of the Indian population, thus, aggregate data recovering to pre-Covid levels are largely academic.
    • An average Indian has lost almost 2 years in terms of income levels and 3 years in terms of spending levels.

    Try this PYQ:

    Q. In the context of Indian economy, consider the following statements:

    1. The growth rate of GDP has steadily increased in the last five years.
    2. The growth rate in per capita income has steadily increased in the last five years.

    Which of the statements given above is/are correct?

    (a) 1 only

    (b) 2 only

    (c) Both 1 and 2

    (d) Neither 1 nor 2

     

    Note: There can be no absolute answers to such questions unless the year is mentioned. Still try to substantiate your answer with the FY21 context.

     

    Do post it here.

     

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  • Zoonotic Diseases: Medical Sciences Involved & Preventive Measures

    Omisure: India’s first RT-PCR kit to identify Omicron strain

    Note4Students

    From UPSC perspective, the following things are important:

    Prelims level: Gene sequencing, RTPCR

    Mains level: COVID diagnosis

    Omisure — India’s first home-grown testing kit has recently received approval from the Drugs Controller General of India.

    About Omisure

    • Omisure is an omicron detecting RT-PCR kit developed by the Mumbai-based Tata Medical and Diagnostics Ltd (TATA MD) in partnership with the Indian Council of Medical Research (ICMR).
    • It can differentiate the omicron strain of the novel coronavirus from the delta, alpha and the other variants in under four hours.
    • It can diagnose this variant in a single step

    How does it work?

    • This new kit can identify the Omicron variant by targeting two regions of the S or the spike gene.
    • This gene codes for the spike protein, which helps the novel coronavirus enter and infect human cells.
    • The S, the Enveloped (E), and Nucleocapsid (N) genes are some of the targets of conventional RT-PCR tests.
    • When it detects these genes, a patient sample is labelled positive. As omicron bears heavy mutations in the S gene, the RT-PCR can sometimes miss it.
    • The absence of S gene likely indicates omicron’s presence.
    • This is called S gene dropout or S gene target failure — and is one of the targets of Omisure.

    How does Omisure compare with gene sequencing?

    • Gene sequencing reads the order of nucleotides, which are the building blocks of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).
    • Despite being considered the gold standard, sequencing has a few limitations.
    • It is slow, expensive and complicated. It is a multi-step process.
    • It begins with extracting the virus’ RNA from patient samples, converting it into DNA, amplifying or multiplying it through RT-PCR before finally sending it for gene sequencing.
    • This entire process can take as many as three days.

    Back2Basics:

    PCR Test for Diagnosis of the COVID-19

     

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